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The map label for this gene is yjcS [H]

Identifier: 170680012

GI number: 170680012

Start: 4650220

End: 4652205

Strand: Reverse

Name: yjcS [H]

Synonym: EcSMS35_4549

Alternate gene names: 170680012

Gene position: 4652205-4650220 (Counterclockwise)

Preceding gene: 170680209

Following gene: 170680201

Centisome position: 91.79

GC content: 50.45

Gene sequence:

>1986_bases
ATGAATAACTCTCGGTTATTCCGTTTGAGCAGGATTGTTATTGCGTTAACTGCCGCCAGCGGCATGATGGTAAATACCGC
TAACGCAACAGATGAAGCGAAAGCCGCCACTCAATATACCCAACAGGTTAATCAGAATTACGCCAAATCATTACCGTTTA
GCGATCGTCAGGATTTTGACGATGCTCAGCGTGGATTTATCGCTCCGCTGCTGGATGAAGGTATTCTGCGCGATGCTAAT
GGCAAACCATATTATCGCGGAGAAGATTATAAATTTGATATCAATGCGCCCGCGCCCGAAACCGTTAACCCAAGCCTGTG
GCGTCAGTCGCAGATCAACGGCATTTCTGGCCTGTTTAAAGTCACCGACCGCATGTATCAGGTGCGCAGCCAGGATATCT
CGAACATCACCTTCATTGAAGGCGATACGGGCATCATCGTCATTGACCCGCTGGTGACGCCAAATGCAGCAAAAGCCAGC
CTTGATCTCTATTTCAAACACCGCCCACAAAAACCGATTGTGGCCGTTATCTACACCCACAGCCACACTGACCACTATGG
CGGCGTAAAAGGTATTGTCTCAGAAGCCGATGTAAAAGCAGGCAAAGTGCAGATCATCGCCCCGGCAGGCTTTATGGACG
AAGCCATCAGTGAAAACGTGCTGGCGGGTAATATCATGAGTCGCCGTGCATTTTACTCTTACGGCCTGCTACTCCCGCAT
AATGCACAGGGAGATATCGGCAACGGGCTGGGTGTTACGCTTACTACCGGCGGCCCGACAATTATCGCGCCGACGCGATC
TATCACCAAGACAGGAGAGAAACTCAATATCGACGGGCTGGATTTCGAATTCCTGATGGCTCCAGGCAGCGAAGCGCCGT
CTGAAATGCACCTCTATATTCCGGCGTTGAAAGCCCTGTGCACAGCGGAAAACAGCACCCATACCCTGCATAACTTCTAC
ACCCTGCGTGGCGCGAAAACCCGTGATACCGCGAAGTGGACCGATTACCTGAATGAAACGCTGGATAAGTGGGGATCACA
AGCAGAAGTGCTGTTTATGCCACATACCTGGCCAGTATGGGGTAATCAACATATCAATGATTATATTGGAAAATATCGCG
ACACCATTAAGTATATTCACGACCAGACCCTGCACCTGGCGAACCAGGGTTACACCATGAATGAAATCGGCAACATGATT
CATCTGCCGGAAACGCTGGATAAAAACTGGGCCAGCCGTGGCTATTATGGCTCCGTCAGTCATAACGCTCGCGCGGTATA
TAACTTTTACCTCGGCTACTACGACGGTAACCCAGCAAACCTGAATCCGTATGGCCAGGTCGATATGGGTAAACGTTATG
TCAAAGCGCTGGGAGGTTCCGCACATGCTATCAATCTGGCGCGTGAAGCCTATAACCAGGGCGACTACCGCTGGGCCTCT
GAACTGCTGAAACAGGTGATTGCTGCCAATCCGGGAGACCAGGTGGCGAAAAACCTACAGGCCGATACCTTCGAACAATT
GGGTTATCAGGCCGAATCAGCCACCTGGCGCGGCTTCTACCTGACGGGAGCGAAAGAACTGCGTGAGGGCGCGAAGAAAA
TCGAACACGCCAGCACCGCCTCTCCTGACACCATCAAGGGTATGACCGTCGAGATGCTGCTTGATTACATGGCTGTTCGT
CTGAACAGTGAGAAAGCCGCGGGCAAATCCATCAGCCTGAACTTCAATCTCTCTGACAACGATAACCTGAACCTCTCACT
CAACAATAGCGTATTGAACTACCGTAAAGTACTGCAACCGAAGGTAGACGCATCGTTTTACATGAGCCGCAGCGATCTGC
ACGACGTGCTGGTCGGACAAGCCAAAATGGCGGATCTGGTAAAGGCGAAGAAAGCCAAAATTATTGGCAATGGCGCAAAA
CTGGAAGAAATTATTGCCTGTCTGGATAATTTCGATTTGTGGGTGAATATCGTAACCCCAAATTAA

Upstream 100 bases:

>100_bases
TATTAAAATCGCAAATTCCCAATTATGATAACGCCAGCTTCAAATGACGTATTTTGCATGGATTACATATTTACGACATA
AATGATAAATGGAGATTTAT

Downstream 100 bases:

>100_bases
TGCCACTCGCTTTTGGGGGCGCTGAAGCCCCCAAAAGCATTTATTTTAAAAATATATACAGACAATTAATAAATAAAATA
TATAAGTTATGAATGCGGTG

Product: metallo-beta-lactamase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 661; Mature: 661

Protein sequence:

>661_residues
MNNSRLFRLSRIVIALTAASGMMVNTANATDEAKAATQYTQQVNQNYAKSLPFSDRQDFDDAQRGFIAPLLDEGILRDAN
GKPYYRGEDYKFDINAPAPETVNPSLWRQSQINGISGLFKVTDRMYQVRSQDISNITFIEGDTGIIVIDPLVTPNAAKAS
LDLYFKHRPQKPIVAVIYTHSHTDHYGGVKGIVSEADVKAGKVQIIAPAGFMDEAISENVLAGNIMSRRAFYSYGLLLPH
NAQGDIGNGLGVTLTTGGPTIIAPTRSITKTGEKLNIDGLDFEFLMAPGSEAPSEMHLYIPALKALCTAENSTHTLHNFY
TLRGAKTRDTAKWTDYLNETLDKWGSQAEVLFMPHTWPVWGNQHINDYIGKYRDTIKYIHDQTLHLANQGYTMNEIGNMI
HLPETLDKNWASRGYYGSVSHNARAVYNFYLGYYDGNPANLNPYGQVDMGKRYVKALGGSAHAINLAREAYNQGDYRWAS
ELLKQVIAANPGDQVAKNLQADTFEQLGYQAESATWRGFYLTGAKELREGAKKIEHASTASPDTIKGMTVEMLLDYMAVR
LNSEKAAGKSISLNFNLSDNDNLNLSLNNSVLNYRKVLQPKVDASFYMSRSDLHDVLVGQAKMADLVKAKKAKIIGNGAK
LEEIIACLDNFDLWVNIVTPN

Sequences:

>Translated_661_residues
MNNSRLFRLSRIVIALTAASGMMVNTANATDEAKAATQYTQQVNQNYAKSLPFSDRQDFDDAQRGFIAPLLDEGILRDAN
GKPYYRGEDYKFDINAPAPETVNPSLWRQSQINGISGLFKVTDRMYQVRSQDISNITFIEGDTGIIVIDPLVTPNAAKAS
LDLYFKHRPQKPIVAVIYTHSHTDHYGGVKGIVSEADVKAGKVQIIAPAGFMDEAISENVLAGNIMSRRAFYSYGLLLPH
NAQGDIGNGLGVTLTTGGPTIIAPTRSITKTGEKLNIDGLDFEFLMAPGSEAPSEMHLYIPALKALCTAENSTHTLHNFY
TLRGAKTRDTAKWTDYLNETLDKWGSQAEVLFMPHTWPVWGNQHINDYIGKYRDTIKYIHDQTLHLANQGYTMNEIGNMI
HLPETLDKNWASRGYYGSVSHNARAVYNFYLGYYDGNPANLNPYGQVDMGKRYVKALGGSAHAINLAREAYNQGDYRWAS
ELLKQVIAANPGDQVAKNLQADTFEQLGYQAESATWRGFYLTGAKELREGAKKIEHASTASPDTIKGMTVEMLLDYMAVR
LNSEKAAGKSISLNFNLSDNDNLNLSLNNSVLNYRKVLQPKVDASFYMSRSDLHDVLVGQAKMADLVKAKKAKIIGNGAK
LEEIIACLDNFDLWVNIVTPN
>Mature_661_residues
MNNSRLFRLSRIVIALTAASGMMVNTANATDEAKAATQYTQQVNQNYAKSLPFSDRQDFDDAQRGFIAPLLDEGILRDAN
GKPYYRGEDYKFDINAPAPETVNPSLWRQSQINGISGLFKVTDRMYQVRSQDISNITFIEGDTGIIVIDPLVTPNAAKAS
LDLYFKHRPQKPIVAVIYTHSHTDHYGGVKGIVSEADVKAGKVQIIAPAGFMDEAISENVLAGNIMSRRAFYSYGLLLPH
NAQGDIGNGLGVTLTTGGPTIIAPTRSITKTGEKLNIDGLDFEFLMAPGSEAPSEMHLYIPALKALCTAENSTHTLHNFY
TLRGAKTRDTAKWTDYLNETLDKWGSQAEVLFMPHTWPVWGNQHINDYIGKYRDTIKYIHDQTLHLANQGYTMNEIGNMI
HLPETLDKNWASRGYYGSVSHNARAVYNFYLGYYDGNPANLNPYGQVDMGKRYVKALGGSAHAINLAREAYNQGDYRWAS
ELLKQVIAANPGDQVAKNLQADTFEQLGYQAESATWRGFYLTGAKELREGAKKIEHASTASPDTIKGMTVEMLLDYMAVR
LNSEKAAGKSISLNFNLSDNDNLNLSLNNSVLNYRKVLQPKVDASFYMSRSDLHDVLVGQAKMADLVKAKKAKIIGNGAK
LEEIIACLDNFDLWVNIVTPN

Specific function: Unknown

COG id: COG2015

COG function: function code Q; Alkyl sulfatase and related hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI87082368, Length=661, Percent_Identity=87.1406959152799, Blast_Score=1205, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6324409, Length=637, Percent_Identity=45.6828885400314, Blast_Score=597, Evalue=1e-171,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR003033 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 73257; Mature: 73257

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNSRLFRLSRIVIALTAASGMMVNTANATDEAKAATQYTQQVNQNYAKSLPFSDRQDFD
CCCCCEEHHHEEEEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
DAQRGFIAPLLDEGILRDANGKPYYRGEDYKFDINAPAPETVNPSLWRQSQINGISGLFK
HHHCCCCCHHHHCCCEECCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHCCCHHHHHH
VTDRMYQVRSQDISNITFIEGDTGIIVIDPLVTPNAAKASLDLYFKHRPQKPIVAVIYTH
HHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCCCCCCEEEEEEECCCCCCEEEEEEEE
SHTDHYGGVKGIVSEADVKAGKVQIIAPAGFMDEAISENVLAGNIMSRRAFYSYGLLLPH
CCCCCCCCHHHHHCCCCCCCCEEEEEECCCHHHHHHHCCCCCCHHHHHHHHHHCCEEECC
NAQGDIGNGLGVTLTTGGPTIIAPTRSITKTGEKLNIDGLDFEFLMAPGSEAPSEMHLYI
CCCCCCCCCCEEEEECCCCEEEECCCHHHCCCCEEECCCCCEEEEECCCCCCCCCEEEEH
PALKALCTAENSTHTLHNFYTLRGAKTRDTAKWTDYLNETLDKWGSQAEVLFMPHTWPVW
HHHHHHHHCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCC
GNQHINDYIGKYRDTIKYIHDQTLHLANQGYTMNEIGNMIHLPETLDKNWASRGYYGSVS
CCCCHHHHHHHHHHHHHHHHHHHEEHHCCCEEHHHHCCEEECCHHHCCCHHCCCCCCCCC
HNARAVYNFYLGYYDGNPANLNPYGQVDMGKRYVKALGGSAHAINLAREAYNQGDYRWAS
CCCEEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHH
ELLKQVIAANPGDQVAKNLQADTFEQLGYQAESATWRGFYLTGAKELREGAKKIEHASTA
HHHHHHHCCCCHHHHHHHCCHHHHHHHCCCCCCCEEEEEEEECHHHHHHHHHHHHHCCCC
SPDTIKGMTVEMLLDYMAVRLNSEKAAGKSISLNFNLSDNDNLNLSLNNSVLNYRKVLQP
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCEEEEECCCHHHHHHHHCC
KVDASFYMSRSDLHDVLVGQAKMADLVKAKKAKIIGNGAKLEEIIACLDNFDLWVNIVTP
CCCHHHEECHHHHHHHHHCHHHHHHHHHHHHHEEECCCCHHHHHHHHHCCCEEEEEEECC
N
C
>Mature Secondary Structure
MNNSRLFRLSRIVIALTAASGMMVNTANATDEAKAATQYTQQVNQNYAKSLPFSDRQDFD
CCCCCEEHHHEEEEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
DAQRGFIAPLLDEGILRDANGKPYYRGEDYKFDINAPAPETVNPSLWRQSQINGISGLFK
HHHCCCCCHHHHCCCEECCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHCCCHHHHHH
VTDRMYQVRSQDISNITFIEGDTGIIVIDPLVTPNAAKASLDLYFKHRPQKPIVAVIYTH
HHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCCCCCCEEEEEEECCCCCCEEEEEEEE
SHTDHYGGVKGIVSEADVKAGKVQIIAPAGFMDEAISENVLAGNIMSRRAFYSYGLLLPH
CCCCCCCCHHHHHCCCCCCCCEEEEEECCCHHHHHHHCCCCCCHHHHHHHHHHCCEEECC
NAQGDIGNGLGVTLTTGGPTIIAPTRSITKTGEKLNIDGLDFEFLMAPGSEAPSEMHLYI
CCCCCCCCCCEEEEECCCCEEEECCCHHHCCCCEEECCCCCEEEEECCCCCCCCCEEEEH
PALKALCTAENSTHTLHNFYTLRGAKTRDTAKWTDYLNETLDKWGSQAEVLFMPHTWPVW
HHHHHHHHCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCC
GNQHINDYIGKYRDTIKYIHDQTLHLANQGYTMNEIGNMIHLPETLDKNWASRGYYGSVS
CCCCHHHHHHHHHHHHHHHHHHHEEHHCCCEEHHHHCCEEECCHHHCCCHHCCCCCCCCC
HNARAVYNFYLGYYDGNPANLNPYGQVDMGKRYVKALGGSAHAINLAREAYNQGDYRWAS
CCCEEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHH
ELLKQVIAANPGDQVAKNLQADTFEQLGYQAESATWRGFYLTGAKELREGAKKIEHASTA
HHHHHHHCCCCHHHHHHHCCHHHHHHHCCCCCCCEEEEEEEECHHHHHHHHHHHHHCCCC
SPDTIKGMTVEMLLDYMAVRLNSEKAAGKSISLNFNLSDNDNLNLSLNNSVLNYRKVLQP
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCEEEEECCCHHHHHHHHCC
KVDASFYMSRSDLHDVLVGQAKMADLVKAKKAKIIGNGAKLEEIIACLDNFDLWVNIVTP
CCCHHHEECHHHHHHHHHCHHHHHHHHHHHHHEEECCCCHHHHHHHHHCCCEEEEEEECC
N
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]