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The map label for this gene is cph1 [H]

Identifier: 170079421

GI number: 170079421

Start: 2958572

End: 2959690

Strand: Reverse

Name: cph1 [H]

Synonym: SYNPCC7002_A2835

Alternate gene names: 170079421

Gene position: 2959690-2958572 (Counterclockwise)

Preceding gene: 170079422

Following gene: 170079420

Centisome position: 98.39

GC content: 40.3

Gene sequence:

>1119_bases
ATGATTCAAGATTCTTATCTGCAGCACCGAGGCGATATTTTAATTGTTGATGATGTTCCTGAAAACCTACAACTTCTTTC
AGAAATTTTGGTTGAAAAGGGCCACGAAGTGCGACAGGTGATCAATGGTAAACAAGCCCTCAAAGCAGTGGCAGCGGATC
CCCCTGATTTGATCCTGCTGGATATTAAAATGCCCATCTTAGATGGTTATGGCGTTTGCCAACGGCTAAAGGCTAATCCA
GACACCGCCAAAATTCCCATTATTTTCATCAGTGCTTTAAATGATGTTTTCGATAAGGTGAAGGCTTTTTCCTTAGGGGG
CGTTGACTATATCAATAAGCCCTTTGATATGTATGAGGTGCTTGTGCGCGTTGAAAATCAACTTAAGATTTTGCGTAATG
CCCAGGAGCTTGAAGAAAAAAATAACCAGTTAGCCCAGATCAACCAAGATCTAAAATCCTTTAACTATATGGTTTCCCAT
GATTTACGGCGGCCATTAACGAAATTGTTAGGGTTTTGTGACTTGCTCTTAGGTGATGTTGATACCTTTGACGAAGAGAC
CTTAGAGACGTTAGAGATTATTGCGAATTCTGCTAAGGAAATGAATCATATCATCTCTGACTTGATGCGCCTTGCAGAAA
TTAAAGAAAAGCAATTAACCCTTGAGAGGATTAATTTAAGTGAAATTGCCACAGAAATTATTCAGGATCTCCAAGGTGAA
ACCCCTGACCGAGCCATAGAAATTAAAATCGAACCGGATGTGATTATCCTAGGCGATCGCCCGCTCCTTAAGATGGCCTT
TGAAAACCTATTTGAAAATGCCTGGAAATACACCAGCAAGGTCAAAAATCCTCAAATAAAATTTTATAAAATTGATTCTC
AAACCTACTGCCTAGAAGATAATGGTGTTGGTTTTACCGCAGAACATCTAGAAGAGATTTTTTTGCCATTTAAGCGACTC
CACACCCAATCTGAATTTGAAGGAACGGGAGTTGGTTTAGCAATTGTTAGGCGTATTATCGAAGTGCATCGGGGACAAAT
CTGGGCCGAAACACGGGTTAACCAAGGGGCTAAATTTTGCTTTACTTTTGGTTTTGATCTCCCCCCAACAAATACTTAG

Upstream 100 bases:

>100_bases
GGTTTAAGCTAAACCAATGTTTTAACGCGCGTAATTCTCATCATTTCAATGTCATCCTGTCAGGGGTAATTCCAAAGCCA
ATGTGGTGAACTTAAGCATT

Downstream 100 bases:

>100_bases
AAAATATTCTGTGAATCACAAAAAAGTGTTTAGAAAATTAGCTTATTAAAAATCAATAAATAACGTCGATTTTGCCTCAT
TAATTTAGTTAAAGCAGCCC

Product: histidine kinase response regulator hybrid protein

Products: NA

Alternate protein names: Bacteriophytochrome cph1; Light-regulated histidine kinase 1 [H]

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MIQDSYLQHRGDILIVDDVPENLQLLSEILVEKGHEVRQVINGKQALKAVAADPPDLILLDIKMPILDGYGVCQRLKANP
DTAKIPIIFISALNDVFDKVKAFSLGGVDYINKPFDMYEVLVRVENQLKILRNAQELEEKNNQLAQINQDLKSFNYMVSH
DLRRPLTKLLGFCDLLLGDVDTFDEETLETLEIIANSAKEMNHIISDLMRLAEIKEKQLTLERINLSEIATEIIQDLQGE
TPDRAIEIKIEPDVIILGDRPLLKMAFENLFENAWKYTSKVKNPQIKFYKIDSQTYCLEDNGVGFTAEHLEEIFLPFKRL
HTQSEFEGTGVGLAIVRRIIEVHRGQIWAETRVNQGAKFCFTFGFDLPPTNT

Sequences:

>Translated_372_residues
MIQDSYLQHRGDILIVDDVPENLQLLSEILVEKGHEVRQVINGKQALKAVAADPPDLILLDIKMPILDGYGVCQRLKANP
DTAKIPIIFISALNDVFDKVKAFSLGGVDYINKPFDMYEVLVRVENQLKILRNAQELEEKNNQLAQINQDLKSFNYMVSH
DLRRPLTKLLGFCDLLLGDVDTFDEETLETLEIIANSAKEMNHIISDLMRLAEIKEKQLTLERINLSEIATEIIQDLQGE
TPDRAIEIKIEPDVIILGDRPLLKMAFENLFENAWKYTSKVKNPQIKFYKIDSQTYCLEDNGVGFTAEHLEEIFLPFKRL
HTQSEFEGTGVGLAIVRRIIEVHRGQIWAETRVNQGAKFCFTFGFDLPPTNT
>Mature_372_residues
MIQDSYLQHRGDILIVDDVPENLQLLSEILVEKGHEVRQVINGKQALKAVAADPPDLILLDIKMPILDGYGVCQRLKANP
DTAKIPIIFISALNDVFDKVKAFSLGGVDYINKPFDMYEVLVRVENQLKILRNAQELEEKNNQLAQINQDLKSFNYMVSH
DLRRPLTKLLGFCDLLLGDVDTFDEETLETLEIIANSAKEMNHIISDLMRLAEIKEKQLTLERINLSEIATEIIQDLQGE
TPDRAIEIKIEPDVIILGDRPLLKMAFENLFENAWKYTSKVKNPQIKFYKIDSQTYCLEDNGVGFTAEHLEEIFLPFKRL
HTQSEFEGTGVGLAIVRRIIEVHRGQIWAETRVNQGAKFCFTFGFDLPPTNT

Specific function: Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. Has also a slight blue shift

COG id: COG4251

COG function: function code T; Bacteriophytochrome (light-regulated signal transduction histidine kinase)

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786783, Length=218, Percent_Identity=27.0642201834862, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1786912, Length=233, Percent_Identity=29.6137339055794, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI145693157, Length=250, Percent_Identity=28.8, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788394, Length=131, Percent_Identity=34.3511450381679, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789809, Length=137, Percent_Identity=33.5766423357664, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790346, Length=202, Percent_Identity=31.1881188118812, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI48994928, Length=243, Percent_Identity=24.6913580246914, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788550, Length=133, Percent_Identity=31.5789473684211, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790299, Length=133, Percent_Identity=31.5789473684211, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788393, Length=226, Percent_Identity=27.8761061946903, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789808, Length=200, Percent_Identity=30, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87082012, Length=117, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1786600, Length=231, Percent_Identity=23.8095238095238, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788549, Length=209, Percent_Identity=27.7511961722488, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789149, Length=227, Percent_Identity=26.8722466960352, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786784, Length=141, Percent_Identity=32.6241134751773, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790436, Length=210, Percent_Identity=24.2857142857143, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790551, Length=100, Percent_Identity=36, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1787894, Length=212, Percent_Identity=26.4150943396226, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790437, Length=118, Percent_Identity=33.8983050847458, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI87081816, Length=224, Percent_Identity=25.4464285714286, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1787229, Length=132, Percent_Identity=28.030303030303, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR000014
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 42439; Mature: 42439

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQDSYLQHRGDILIVDDVPENLQLLSEILVEKGHEVRQVINGKQALKAVAADPPDLILL
CCCCHHHHHCCCEEEECCCCHHHHHHHHHHHHCCHHHHHHHCHHHHHHHHHCCCCCEEEE
DIKMPILDGYGVCQRLKANPDTAKIPIIFISALNDVFDKVKAFSLGGVDYINKPFDMYEV
EEECCCCCCHHHHHHHCCCCCCCEEHEEHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHH
LVRVENQLKILRNAQELEEKNNQLAQINQDLKSFNYMVSHDLRRPLTKLLGFCDLLLGDV
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DTFDEETLETLEIIANSAKEMNHIISDLMRLAEIKEKQLTLERINLSEIATEIIQDLQGE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
TPDRAIEIKIEPDVIILGDRPLLKMAFENLFENAWKYTSKVKNPQIKFYKIDSQTYCLED
CCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEC
NGVGFTAEHLEEIFLPFKRLHTQSEFEGTGVGLAIVRRIIEVHRGQIWAETRVNQGAKFC
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCEEEHHHHCCCCCEE
FTFGFDLPPTNT
EEECCCCCCCCC
>Mature Secondary Structure
MIQDSYLQHRGDILIVDDVPENLQLLSEILVEKGHEVRQVINGKQALKAVAADPPDLILL
CCCCHHHHHCCCEEEECCCCHHHHHHHHHHHHCCHHHHHHHCHHHHHHHHHCCCCCEEEE
DIKMPILDGYGVCQRLKANPDTAKIPIIFISALNDVFDKVKAFSLGGVDYINKPFDMYEV
EEECCCCCCHHHHHHHCCCCCCCEEHEEHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHH
LVRVENQLKILRNAQELEEKNNQLAQINQDLKSFNYMVSHDLRRPLTKLLGFCDLLLGDV
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DTFDEETLETLEIIANSAKEMNHIISDLMRLAEIKEKQLTLERINLSEIATEIIQDLQGE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
TPDRAIEIKIEPDVIILGDRPLLKMAFENLFENAWKYTSKVKNPQIKFYKIDSQTYCLED
CCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEC
NGVGFTAEHLEEIFLPFKRLHTQSEFEGTGVGLAIVRRIIEVHRGQIWAETRVNQGAKFC
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCEEEHHHHCCCCCEE
FTFGFDLPPTNT
EEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9109482; 9278513; 10828948 [H]