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The map label for this gene is gltA [H]

Identifier: 170079217

GI number: 170079217

Start: 2751615

End: 2752757

Strand: Direct

Name: gltA [H]

Synonym: SYNPCC7002_A2623

Alternate gene names: 170079217

Gene position: 2751615-2752757 (Clockwise)

Preceding gene: 170079216

Following gene: 170079218

Centisome position: 91.48

GC content: 50.48

Gene sequence:

>1143_bases
ATGACGACTGGTTGCGAATTTAAACCCGGCTTAGAAGGAATTCCTGCAGCCCAATCCAGCATTAGCTTCGTCGATGGAAA
AAATGGCATCCTCGAATACCGGGGGATCCCGATTCAAGAATTGGCCGAAAAAAGTTCTTTCCTCGAAGTTGCCTACCTCC
TGATCTGGGGTGAACTGCCGACCTACCAGGAACTTGAAGATTTTAAAAACGATATTCTCTATCATCGTCGGATTAAATAC
CGCATCCGAGACATGATGAAATGTTTTCCGGAAACCGGTCACCCGATGGATTCTCTGCAAACGTCGGCGGCGGCCCTGGG
GCTATTTTATTCCCGGCGTGCCTTGGATGATCCAGAGTACATTCGCCACGCTGTTGTTCGTCTGTTAGCCAAAATCCCCA
CCATGGTTGCGGCGGCCAATTCGATGCGCAAAGGAAATGATCCGGTTCAGCCCAACGATAGCCTTGATTATGCGGCGAAT
TTTCTCTACATGATGACCGAGCGTCGCCCCTACGATCTCCAGGCGAAGATTTTTGATATTTGCTTGATGCTCCACGCCGA
ACACACGATCAATGCTTCCACTTTTTCGGCGATGGTGACGGCTTCTACCTTGACGGATCCCTACGCGGTGATTGCGTCTG
CCGTTGGCACCTTGGCCGGGCCGTTGCATGGAGGGGCGAACGAAGAAGTGCTTTTGATGCTCGAAGAAATTGGCTCCGTC
GAAAATGTTCGTGGGTATGTCGAGACCTGTGTCGCGAATAAACAAAAGATCATGGGCTTCGGCCACCGGGTTTATAAGGT
TAAAGATCCCCGGGCGGTGATCCTCCAGAGGTTAGCGGAGGAACTGTTCGAACTCGAAGGGGAAGACCCGTACTACAAGA
TTGCCCTGGAATTAGAAAAAATCGTTGAGGAAAAATACGGCCACAAGGGGATTTTCGCCAACGTTGATTTCTATTCGGGC
TTGGTTTACCGCAAGTTAGGGATTCCGAGCGATCTATTTACGCCCTTGTTTGCGATCGCCAGGGTTGCAGGTTGGCTCGC
CCACTGGAAAGAACAACTGGGTGTCAACCGGATTTTCCGACCGACCCAGGTCTATACCGGTGTGCATAATCAAATCTATA
TTCCAGTAGAAAAACGCGGCTAA

Upstream 100 bases:

>100_bases
AAATGGCTACTGCCATAATCCCCGTGATAGGCTAAGTTAGCCACGGGCATCAAGAAATTAGCCTCAATATTATTTTTAGG
ATCTAATCAAGGTACACAGT

Downstream 100 bases:

>100_bases
AGGGACAGTGTTCACGATGCAATTATGCCGATGGCGCAGCTTAGGACTGGGGGTATTGCTGCTCTTTCTGTGGGGCTGTG
GGGCAAATCCCCCTGGCCTG

Product: citrate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MTTGCEFKPGLEGIPAAQSSISFVDGKNGILEYRGIPIQELAEKSSFLEVAYLLIWGELPTYQELEDFKNDILYHRRIKY
RIRDMMKCFPETGHPMDSLQTSAAALGLFYSRRALDDPEYIRHAVVRLLAKIPTMVAAANSMRKGNDPVQPNDSLDYAAN
FLYMMTERRPYDLQAKIFDICLMLHAEHTINASTFSAMVTASTLTDPYAVIASAVGTLAGPLHGGANEEVLLMLEEIGSV
ENVRGYVETCVANKQKIMGFGHRVYKVKDPRAVILQRLAEELFELEGEDPYYKIALELEKIVEEKYGHKGIFANVDFYSG
LVYRKLGIPSDLFTPLFAIARVAGWLAHWKEQLGVNRIFRPTQVYTGVHNQIYIPVEKRG

Sequences:

>Translated_380_residues
MTTGCEFKPGLEGIPAAQSSISFVDGKNGILEYRGIPIQELAEKSSFLEVAYLLIWGELPTYQELEDFKNDILYHRRIKY
RIRDMMKCFPETGHPMDSLQTSAAALGLFYSRRALDDPEYIRHAVVRLLAKIPTMVAAANSMRKGNDPVQPNDSLDYAAN
FLYMMTERRPYDLQAKIFDICLMLHAEHTINASTFSAMVTASTLTDPYAVIASAVGTLAGPLHGGANEEVLLMLEEIGSV
ENVRGYVETCVANKQKIMGFGHRVYKVKDPRAVILQRLAEELFELEGEDPYYKIALELEKIVEEKYGHKGIFANVDFYSG
LVYRKLGIPSDLFTPLFAIARVAGWLAHWKEQLGVNRIFRPTQVYTGVHNQIYIPVEKRG
>Mature_379_residues
TTGCEFKPGLEGIPAAQSSISFVDGKNGILEYRGIPIQELAEKSSFLEVAYLLIWGELPTYQELEDFKNDILYHRRIKYR
IRDMMKCFPETGHPMDSLQTSAAALGLFYSRRALDDPEYIRHAVVRLLAKIPTMVAAANSMRKGNDPVQPNDSLDYAANF
LYMMTERRPYDLQAKIFDICLMLHAEHTINASTFSAMVTASTLTDPYAVIASAVGTLAGPLHGGANEEVLLMLEEIGSVE
NVRGYVETCVANKQKIMGFGHRVYKVKDPRAVILQRLAEELFELEGEDPYYKIALELEKIVEEKYGHKGIFANVDFYSGL
VYRKLGIPSDLFTPLFAIARVAGWLAHWKEQLGVNRIFRPTQVYTGVHNQIYIPVEKRG

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0372

COG function: function code C; Citrate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the citrate synthase family [H]

Homologues:

Organism=Homo sapiens, GI38327625, Length=393, Percent_Identity=28.498727735369, Blast_Score=120, Evalue=2e-27,
Organism=Escherichia coli, GI1786939, Length=385, Percent_Identity=39.4805194805195, Blast_Score=276, Evalue=2e-75,
Organism=Escherichia coli, GI1786527, Length=370, Percent_Identity=35.1351351351351, Blast_Score=230, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI17555174, Length=380, Percent_Identity=28.4210526315789, Blast_Score=112, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6319850, Length=410, Percent_Identity=27.3170731707317, Blast_Score=111, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6325257, Length=392, Percent_Identity=24.7448979591837, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6324328, Length=413, Percent_Identity=25.6658595641646, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24640126, Length=391, Percent_Identity=28.6445012787724, Blast_Score=128, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24640124, Length=391, Percent_Identity=28.6445012787724, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI21356863, Length=382, Percent_Identity=28.5340314136126, Blast_Score=119, Evalue=3e-27,

Paralogues:

None

Copy number: 624 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011278
- InterPro:   IPR016142
- InterPro:   IPR016143
- InterPro:   IPR002020
- InterPro:   IPR016141
- InterPro:   IPR019810 [H]

Pfam domain/function: PF00285 Citrate_synt [H]

EC number: =2.3.3.1 [H]

Molecular weight: Translated: 42842; Mature: 42711

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00480 CITRATE_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTGCEFKPGLEGIPAAQSSISFVDGKNGILEYRGIPIQELAEKSSFLEVAYLLIWGELP
CCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCC
TYQELEDFKNDILYHRRIKYRIRDMMKCFPETGHPMDSLQTSAAALGLFYSRRALDDPEY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHH
IRHAVVRLLAKIPTMVAAANSMRKGNDPVQPNDSLDYAANFLYMMTERRPYDLQAKIFDI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHH
CLMLHAEHTINASTFSAMVTASTLTDPYAVIASAVGTLAGPLHGGANEEVLLMLEEIGSV
HHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCH
ENVRGYVETCVANKQKIMGFGHRVYKVKDPRAVILQRLAEELFELEGEDPYYKIALELEK
HHHHHHHHHHHHCHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCEEHHHHHHH
IVEEKYGHKGIFANVDFYSGLVYRKLGIPSDLFTPLFAIARVAGWLAHWKEQLGVNRIFR
HHHHHCCCCCEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCC
PTQVYTGVHNQIYIPVEKRG
CHHHHCCCCCEEEEEEECCC
>Mature Secondary Structure 
TTGCEFKPGLEGIPAAQSSISFVDGKNGILEYRGIPIQELAEKSSFLEVAYLLIWGELP
CCCCCCCCCCCCCCCCCCCCEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCC
TYQELEDFKNDILYHRRIKYRIRDMMKCFPETGHPMDSLQTSAAALGLFYSRRALDDPEY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHH
IRHAVVRLLAKIPTMVAAANSMRKGNDPVQPNDSLDYAANFLYMMTERRPYDLQAKIFDI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHH
CLMLHAEHTINASTFSAMVTASTLTDPYAVIASAVGTLAGPLHGGANEEVLLMLEEIGSV
HHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCH
ENVRGYVETCVANKQKIMGFGHRVYKVKDPRAVILQRLAEELFELEGEDPYYKIALELEK
HHHHHHHHHHHHCHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCEEHHHHHHH
IVEEKYGHKGIFANVDFYSGLVYRKLGIPSDLFTPLFAIARVAGWLAHWKEQLGVNRIFR
HHHHHCCCCCEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCC
PTQVYTGVHNQIYIPVEKRG
CHHHHCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]