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The map label for this gene is sppA [C]

Identifier: 170079132

GI number: 170079132

Start: 2643247

End: 2644065

Strand: Reverse

Name: sppA [C]

Synonym: SYNPCC7002_A2538

Alternate gene names: 170079132

Gene position: 2644065-2643247 (Counterclockwise)

Preceding gene: 170079134

Following gene: 170079131

Centisome position: 87.9

GC content: 51.53

Gene sequence:

>819_bases
ATGGTGTGGCCGTTTCCTCCGAAAACCCGTAAACAAGTTGCGCGTATTGAAATCACCGGGGCGATCGCCGCTGATACCCG
AAAACGAGTCCTGAAAGCCCTCGAAGAAGTCGAAGAGAAAAAATATCCGGCCCTGCTGTTGCGGATCGATTCCCCTGGGG
GCACCGTGGGCGACTCCCAAGAAATTTATTACGCCCTCAAAAAACTCCAGGAAAAAACAAAGATTGTCGCCAGCTTTGGC
AATATTTCGGCTTCCGGGGGCGTTTACATCGGCATGGGAGCGCAGCATATCGTTGCAAATCCGGGGACAATTACAGGCAG
CATCGGCGTTATTTTGCGGGGCAATAACCTAGAGCGGCTCCTCGAAAAGGTTGGTGTCTCTTTTAAGGTGATTAAGTCTG
GCCCTTACAAGGATATTTTGTCCTTTGACCGGGAGTTGACCGAGGCGGAAGAAAATATTCTCCAGGAAATGATCGATGTC
AGCTACGGCCAGTTTGTCAAAACTGTCGCCGAAGCCCGCAATCTGGATGTGGAAACAGTGAAAACCTTTGCCGATGGTCG
CATTTTTACCGGAGAGCAAGCGCAGGAACTTGGTGTCGTTGATCGCCTCGGCACCGAAGAAGATGCACGCATTTGGGCCG
CAAAATTAGCGGGCTTAGATCCAGATAAGGCAGAATGTCGCACCATTGAGGAACCCAAACCCCTGATTACTCGCCTTTTG
AGTCGCAATCAACTGAGTTCGCCCGTGGGGAACGCCCTTAATTGGGTAGAATTTGAACTGGCAACGGCGGGACAACCCCT
GTGGCTCTATCGACCCTAA

Upstream 100 bases:

>100_bases
GGTAAGACCCAGCGGATCAGTTAGCATAGGGGATTAGTGCCCTCAACGTCTAATCTGCAGGGCCTGCTAACATTTCATTA
TTTATTTTTGACAAATCCCT

Downstream 100 bases:

>100_bases
TTTCGAAAATTTTTGATGCTTGAGGCGGAGGAAACCAACGTGGACTGGAAGGTGCGGGCTATTCGAGGCGCAATTACAGC
AACGGCCAATACCAAGGAGG

Product: signal peptide peptidase SppA, 36K type

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MVWPFPPKTRKQVARIEITGAIAADTRKRVLKALEEVEEKKYPALLLRIDSPGGTVGDSQEIYYALKKLQEKTKIVASFG
NISASGGVYIGMGAQHIVANPGTITGSIGVILRGNNLERLLEKVGVSFKVIKSGPYKDILSFDRELTEAEENILQEMIDV
SYGQFVKTVAEARNLDVETVKTFADGRIFTGEQAQELGVVDRLGTEEDARIWAAKLAGLDPDKAECRTIEEPKPLITRLL
SRNQLSSPVGNALNWVEFELATAGQPLWLYRP

Sequences:

>Translated_272_residues
MVWPFPPKTRKQVARIEITGAIAADTRKRVLKALEEVEEKKYPALLLRIDSPGGTVGDSQEIYYALKKLQEKTKIVASFG
NISASGGVYIGMGAQHIVANPGTITGSIGVILRGNNLERLLEKVGVSFKVIKSGPYKDILSFDRELTEAEENILQEMIDV
SYGQFVKTVAEARNLDVETVKTFADGRIFTGEQAQELGVVDRLGTEEDARIWAAKLAGLDPDKAECRTIEEPKPLITRLL
SRNQLSSPVGNALNWVEFELATAGQPLWLYRP
>Mature_272_residues
MVWPFPPKTRKQVARIEITGAIAADTRKRVLKALEEVEEKKYPALLLRIDSPGGTVGDSQEIYYALKKLQEKTKIVASFG
NISASGGVYIGMGAQHIVANPGTITGSIGVILRGNNLERLLEKVGVSFKVIKSGPYKDILSFDRELTEAEENILQEMIDV
SYGQFVKTVAEARNLDVETVKTFADGRIFTGEQAQELGVVDRLGTEEDARIWAAKLAGLDPDKAECRTIEEPKPLITRLL
SRNQLSSPVGNALNWVEFELATAGQPLWLYRP

Specific function: Digestion Of The Cleaved Signal Peptides. This Activity Is Necessary To Maintain Proper Secretion Of Mature Proteins Across The Membrane. [C]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1788064, Length=202, Percent_Identity=35.1485148514851, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1787527, Length=166, Percent_Identity=31.3253012048193, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004635
- InterPro:   IPR002142 [H]

Pfam domain/function: PF01343 Peptidase_S49 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 29999; Mature: 29999

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVWPFPPKTRKQVARIEITGAIAADTRKRVLKALEEVEEKKYPALLLRIDSPGGTVGDSQ
CCCCCCCHHHHHEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHH
EIYYALKKLQEKTKIVASFGNISASGGVYIGMGAQHIVANPGTITGSIGVILRGNNLERL
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEECCCEEEECEEEEEECCCHHHH
LEKVGVSFKVIKSGPYKDILSFDRELTEAEENILQEMIDVSYGQFVKTVAEARNLDVETV
HHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHH
KTFADGRIFTGEQAQELGVVDRLGTEEDARIWAAKLAGLDPDKAECRTIEEPKPLITRLL
HHHHCCCEECCCHHHHCCHHHHCCCCHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHH
SRNQLSSPVGNALNWVEFELATAGQPLWLYRP
HHHHCCCCHHHCCCCEEEEEECCCCCEEEECC
>Mature Secondary Structure
MVWPFPPKTRKQVARIEITGAIAADTRKRVLKALEEVEEKKYPALLLRIDSPGGTVGDSQ
CCCCCCCHHHHHEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHH
EIYYALKKLQEKTKIVASFGNISASGGVYIGMGAQHIVANPGTITGSIGVILRGNNLERL
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEECCCEEEECEEEEEECCCHHHH
LEKVGVSFKVIKSGPYKDILSFDRELTEAEENILQEMIDVSYGQFVKTVAEARNLDVETV
HHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHH
KTFADGRIFTGEQAQELGVVDRLGTEEDARIWAAKLAGLDPDKAECRTIEEPKPLITRLL
HHHHCCCEECCCHHHHCCHHHHCCCCHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHH
SRNQLSSPVGNALNWVEFELATAGQPLWLYRP
HHHHCCCCHHHCCCCEEEEEECCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]