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The map label for this gene is carA [H]

Identifier: 170079100

GI number: 170079100

Start: 2611109

End: 2612251

Strand: Direct

Name: carA [H]

Synonym: SYNPCC7002_A2505

Alternate gene names: 170079100

Gene position: 2611109-2612251 (Clockwise)

Preceding gene: 170079099

Following gene: 170079102

Centisome position: 86.8

GC content: 52.76

Gene sequence:

>1143_bases
ATGTCTCTTGTGAAAGCAAAACCCGCCCTCCTTGTTTTAGCCGATGGCACCACTTACCACGGACGGTCATTTGGCGCGAC
AGGTACCACCTTTGGGGAAGTCGTTTTTAATACAGGCATGACGGGCTACCAAGAAGTCCTCACCGATCCCAGTTACCGTG
GTCAGATTGTGACTTTTACCTATCCGGAGCTGGGCAATACTGGCGTAACTCCTGAAGACGAAGAATCCAGCCGTCCCCAA
GTAAAAGGGGCGATCGCCCGGAACATTGCTCCCCGACCGAGCAACTGGCGTTCTACCCAGGCCCTACCCGATTATCTCAA
AGAGCACCAAGTTGTGGGCATCTATGGCATTGATACGCGGGATCTAACCCGTCGCCTGCGGGTATCTGGGGCGATGAATG
GCGCGATCTCTACAGAAATCCTCGACCCCGAAGAACTTCTCCGCCAACTCCAAGACGTCCCCTCCATGGAAGGCCAAAAC
CTCGTCAAGGATGTCACCACCGCTAGCGTTTATGAATGGACGGAAATTACCGATCGCCATTGGGAATTTAGCAGTAGCGC
AACTGAAGCCCAGGAACTCACCGTCGTTGCCATTGACTTTGGTGTGAAACGCAATATTCTGCGCCGTTTGGCGAGTTATG
GCTGCCGGGTAATCGTTGTTCCCGCCGACACCCCCGCCGAAAAAATCCTTGCCTATAATCCCGATGGCATTTTCCTTTCC
AATGGCCCTGGGGATCCAGCCGCCGTCACCGAAGGCATCGCCACGGTTAAAGATATTCTTAAGGCTGAAAAACCCACCTT
CGGCATTTGCATGGGGCACCAAATTCTGGGGCTTTCATTGGGGGCTGAAACTTTTAAACTCAAATTTGGCCACCGGGGTC
TCAACCAACCCGCTGGTCTCAAGCAAAAGCAAATTGAAATTACCAGCCAAAACCATGGGTTTGCGATCGCCGAAGCCTCC
CTCGCCGAAGATGTTGCCATTACCCACCTCAACCTCAATGACCGCACTGTCGCTGGCTTAGAACATAAAACCTTGCCTTT
CTTCTCGGTGCAGTATCACCCTGAAGCGAGCCCCGGCCCCCACGATGCTGACTACCTCTTTGAAAAATTTGTGCGTTCCA
TGAAAGCCCACAAAAATGCCTAA

Upstream 100 bases:

>100_bases
AAAAATTAACGGCGATCGCCCCAAGGAGCGGTAGAGAAGGGAACGGATCAAGTAAGATTGAGCAGCAGAAGTTACGCATA
TATCAAAGGTCAATCCGCCC

Downstream 100 bases:

>100_bases
AGGCGACGGTACCGCATCCCTGGCAGTTGGGTAATGAATCCTTCGAGTTCCCATTGCAATAGGGTCGCCGAAACCTGATC
TGCCCCCATGCCAGACTGGA

Product: carbamoyl phosphate synthase small subunit

Products: NA

Alternate protein names: Carbamoyl-phosphate synthetase glutamine chain [H]

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MSLVKAKPALLVLADGTTYHGRSFGATGTTFGEVVFNTGMTGYQEVLTDPSYRGQIVTFTYPELGNTGVTPEDEESSRPQ
VKGAIARNIAPRPSNWRSTQALPDYLKEHQVVGIYGIDTRDLTRRLRVSGAMNGAISTEILDPEELLRQLQDVPSMEGQN
LVKDVTTASVYEWTEITDRHWEFSSSATEAQELTVVAIDFGVKRNILRRLASYGCRVIVVPADTPAEKILAYNPDGIFLS
NGPGDPAAVTEGIATVKDILKAEKPTFGICMGHQILGLSLGAETFKLKFGHRGLNQPAGLKQKQIEITSQNHGFAIAEAS
LAEDVAITHLNLNDRTVAGLEHKTLPFFSVQYHPEASPGPHDADYLFEKFVRSMKAHKNA

Sequences:

>Translated_380_residues
MSLVKAKPALLVLADGTTYHGRSFGATGTTFGEVVFNTGMTGYQEVLTDPSYRGQIVTFTYPELGNTGVTPEDEESSRPQ
VKGAIARNIAPRPSNWRSTQALPDYLKEHQVVGIYGIDTRDLTRRLRVSGAMNGAISTEILDPEELLRQLQDVPSMEGQN
LVKDVTTASVYEWTEITDRHWEFSSSATEAQELTVVAIDFGVKRNILRRLASYGCRVIVVPADTPAEKILAYNPDGIFLS
NGPGDPAAVTEGIATVKDILKAEKPTFGICMGHQILGLSLGAETFKLKFGHRGLNQPAGLKQKQIEITSQNHGFAIAEAS
LAEDVAITHLNLNDRTVAGLEHKTLPFFSVQYHPEASPGPHDADYLFEKFVRSMKAHKNA
>Mature_379_residues
SLVKAKPALLVLADGTTYHGRSFGATGTTFGEVVFNTGMTGYQEVLTDPSYRGQIVTFTYPELGNTGVTPEDEESSRPQV
KGAIARNIAPRPSNWRSTQALPDYLKEHQVVGIYGIDTRDLTRRLRVSGAMNGAISTEILDPEELLRQLQDVPSMEGQNL
VKDVTTASVYEWTEITDRHWEFSSSATEAQELTVVAIDFGVKRNILRRLASYGCRVIVVPADTPAEKILAYNPDGIFLSN
GPGDPAAVTEGIATVKDILKAEKPTFGICMGHQILGLSLGAETFKLKFGHRGLNQPAGLKQKQIEITSQNHGFAIAEASL
AEDVAITHLNLNDRTVAGLEHKTLPFFSVQYHPEASPGPHDADYLFEKFVRSMKAHKNA

Specific function: Arginine biosynthesis. Pyrimidine biosynthesis; first step. [C]

COG id: COG0505

COG function: function code EF; Carbamoylphosphate synthase small subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=381, Percent_Identity=39.6325459317585, Blast_Score=265, Evalue=4e-71,
Organism=Homo sapiens, GI21361331, Length=388, Percent_Identity=38.1443298969072, Blast_Score=243, Evalue=3e-64,
Organism=Homo sapiens, GI169790915, Length=388, Percent_Identity=38.1443298969072, Blast_Score=242, Evalue=4e-64,
Organism=Escherichia coli, GI1786215, Length=379, Percent_Identity=49.868073878628, Blast_Score=373, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI193204318, Length=387, Percent_Identity=38.7596899224806, Blast_Score=252, Evalue=2e-67,
Organism=Saccharomyces cerevisiae, GI6322331, Length=392, Percent_Identity=37.7551020408163, Blast_Score=250, Evalue=2e-67,
Organism=Saccharomyces cerevisiae, GI6324878, Length=389, Percent_Identity=37.5321336760925, Blast_Score=236, Evalue=5e-63,
Organism=Drosophila melanogaster, GI45555749, Length=385, Percent_Identity=36.3636363636364, Blast_Score=230, Evalue=2e-60,
Organism=Drosophila melanogaster, GI24642586, Length=385, Percent_Identity=36.3636363636364, Blast_Score=229, Evalue=2e-60,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2599 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR006274
- InterPro:   IPR002474
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991 [H]

Pfam domain/function: PF00988 CPSase_sm_chain; PF00117 GATase [H]

EC number: =6.3.5.5 [H]

Molecular weight: Translated: 41538; Mature: 41407

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLVKAKPALLVLADGTTYHGRSFGATGTTFGEVVFNTGMTGYQEVLTDPSYRGQIVTFT
CCCCCCCCEEEEEECCCEECCCCCCCCCCHHHHHHHHCCCCHHHHHHCCCCCCCEEEEEE
YPELGNTGVTPEDEESSRPQVKGAIARNIAPRPSNWRSTQALPDYLKEHQVVGIYGIDTR
CCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCEEEEEECCHH
DLTRRLRVSGAMNGAISTEILDPEELLRQLQDVPSMEGQNLVKDVTTASVYEWTEITDRH
HHHHHHHHHHCCCCCCEEECCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHEEHHHHCCCC
WEFSSSATEAQELTVVAIDFGVKRNILRRLASYGCRVIVVPADTPAEKILAYNPDGIFLS
EECCCCCCCCCEEEEEEEECCHHHHHHHHHHHCCCEEEEEECCCCHHHEEEECCCEEEEE
NGPGDPAAVTEGIATVKDILKAEKPTFGICMGHQILGLSLGAETFKLKFGHRGLNQPAGL
CCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEEECCCCEEEEEECCCCCCCCCCC
KQKQIEITSQNHGFAIAEASLAEDVAITHLNLNDRTVAGLEHKTLPFFSVQYHPEASPGP
CCEEEEEECCCCCEEEEEHHHCCCEEEEEECCCCCEEECCCCCCCCEEEEEECCCCCCCC
HDADYLFEKFVRSMKAHKNA
CCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLVKAKPALLVLADGTTYHGRSFGATGTTFGEVVFNTGMTGYQEVLTDPSYRGQIVTFT
CCCCCCCEEEEEECCCEECCCCCCCCCCHHHHHHHHCCCCHHHHHHCCCCCCCEEEEEE
YPELGNTGVTPEDEESSRPQVKGAIARNIAPRPSNWRSTQALPDYLKEHQVVGIYGIDTR
CCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCEEEEEECCHH
DLTRRLRVSGAMNGAISTEILDPEELLRQLQDVPSMEGQNLVKDVTTASVYEWTEITDRH
HHHHHHHHHHCCCCCCEEECCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHEEHHHHCCCC
WEFSSSATEAQELTVVAIDFGVKRNILRRLASYGCRVIVVPADTPAEKILAYNPDGIFLS
EECCCCCCCCCEEEEEEEECCHHHHHHHHHHHCCCEEEEEECCCCHHHEEEECCCEEEEE
NGPGDPAAVTEGIATVKDILKAEKPTFGICMGHQILGLSLGAETFKLKFGHRGLNQPAGL
CCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEEECCCCEEEEEECCCCCCCCCCC
KQKQIEITSQNHGFAIAEASLAEDVAITHLNLNDRTVAGLEHKTLPFFSVQYHPEASPGP
CCEEEEEECCCCCEEEEEHHHCCCEEEEEECCCCCEEECCCCCCCCEEEEEECCCCCCCC
HDADYLFEKFVRSMKAHKNA
CCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]