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The map label for this gene is apqZ [H]

Identifier: 170079023

GI number: 170079023

Start: 2522494

End: 2523249

Strand: Direct

Name: apqZ [H]

Synonym: SYNPCC7002_A2428

Alternate gene names: 170079023

Gene position: 2522494-2523249 (Clockwise)

Preceding gene: 170079022

Following gene: 170079025

Centisome position: 83.86

GC content: 50.93

Gene sequence:

>756_bases
ATGAAGAAATACATTGCAGAATTTCTAGGGACATTCTGGTTGGTTCTGGGGGGATGTGGCAGTGCTGTTTTTGCCGCCGT
CGTCGCCCTATCCGACGCTGACCTTTCCAACGGGTTAGGTCTGGGTTTTCTGGGGGTTTCCCTGGCCTTTGGTTTAACAG
TTGTGACTGGCGCCTATGCTTTCGGGCATATTTCTGGTGGCCATTTTAACCCGGCAGTTTCCTTTGGCCTATGGGCCGCC
AAACGCTTTCCTGGGCATGAATTACTTCCCTATATCGTGGCCCAGGTGTTGGGAGGAGCTTTAGCTGGCCTTGTCATTTT
GGTAGTCGGCAGTGGCAATGGCGCCTTAGACTTATCCGGCTCGAATCCCCTGGCTACCAACGGCTTTGGGAGTCATTCTC
CAGGTGGCTATGGCTTACTGGCGGCTTTGATTACCGAAATTGTCATGACCTTTATGTTTTTGATGATTATTTTGGGTTCC
ACAGATCGCCGTGCCCCCGCTGGTTTTGCCCCAGTTGCCATTGGTCTTGGTTTAACATTGATTCACCTGATCAGTATTCC
AATCACCAATACCTCGGTCAATCCGGCTCGGAGTACAGGCGTCGCTCTCTTTTGTGGCAACGTTGAATTAATCGGTCAGC
TATGGCTCTTTTGGGTAGCACCTATTTTTGGGGCGATCGCCGCAGGATATGCCTATAGTGCTTTCTTTAGCGAAACAAAA
GATACAACGGGTACTGGGGCGCCGACGATCGCTTAG

Upstream 100 bases:

>100_bases
ACGTAAATATCTTTAGTGAACTCTTATGACAAAAAAGCGCCTCTTCATTGGAGTTGAAAAGAAAATTGTGTATGTAGTCT
ATTTGTAATTGGCGACATAC

Downstream 100 bases:

>100_bases
GCCCATACCAGACATAATCTTTACCTGATATTTCCCCCATCGCTTGATTTTTCAAAACCTGGGGGATTTTTTATGGTCAA
TCTCTGGAATTAAGTCCGCT

Product: aquaporin Z

Products: H2O [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MKKYIAEFLGTFWLVLGGCGSAVFAAVVALSDADLSNGLGLGFLGVSLAFGLTVVTGAYAFGHISGGHFNPAVSFGLWAA
KRFPGHELLPYIVAQVLGGALAGLVILVVGSGNGALDLSGSNPLATNGFGSHSPGGYGLLAALITEIVMTFMFLMIILGS
TDRRAPAGFAPVAIGLGLTLIHLISIPITNTSVNPARSTGVALFCGNVELIGQLWLFWVAPIFGAIAAGYAYSAFFSETK
DTTGTGAPTIA

Sequences:

>Translated_251_residues
MKKYIAEFLGTFWLVLGGCGSAVFAAVVALSDADLSNGLGLGFLGVSLAFGLTVVTGAYAFGHISGGHFNPAVSFGLWAA
KRFPGHELLPYIVAQVLGGALAGLVILVVGSGNGALDLSGSNPLATNGFGSHSPGGYGLLAALITEIVMTFMFLMIILGS
TDRRAPAGFAPVAIGLGLTLIHLISIPITNTSVNPARSTGVALFCGNVELIGQLWLFWVAPIFGAIAAGYAYSAFFSETK
DTTGTGAPTIA
>Mature_251_residues
MKKYIAEFLGTFWLVLGGCGSAVFAAVVALSDADLSNGLGLGFLGVSLAFGLTVVTGAYAFGHISGGHFNPAVSFGLWAA
KRFPGHELLPYIVAQVLGGALAGLVILVVGSGNGALDLSGSNPLATNGFGSHSPGGYGLLAALITEIVMTFMFLMIILGS
TDRRAPAGFAPVAIGLGLTLIHLISIPITNTSVNPARSTGVALFCGNVELIGQLWLFWVAPIFGAIAAGYAYSAFFSETK
DTTGTGAPTIA

Specific function: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response

COG id: COG0580

COG function: function code G; Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MIP/aquaporin (TC 1.A.8) family [H]

Homologues:

Organism=Homo sapiens, GI37694062, Length=235, Percent_Identity=36.1702127659575, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI4755125, Length=243, Percent_Identity=33.7448559670782, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI4502181, Length=243, Percent_Identity=33.7448559670782, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4502183, Length=234, Percent_Identity=35.4700854700855, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI4502179, Length=234, Percent_Identity=32.0512820512821, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI6912506, Length=228, Percent_Identity=31.140350877193, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI157266307, Length=252, Percent_Identity=31.3492063492063, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI4826645, Length=252, Percent_Identity=32.5396825396825, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI45446752, Length=200, Percent_Identity=31, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI4502187, Length=258, Percent_Identity=28.6821705426357, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI86792455, Length=240, Percent_Identity=29.5833333333333, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1787101, Length=217, Percent_Identity=58.9861751152074, Blast_Score=240, Evalue=8e-65,
Organism=Escherichia coli, GI1790362, Length=281, Percent_Identity=29.8932384341637, Blast_Score=75, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71993722, Length=247, Percent_Identity=31.9838056680162, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17558372, Length=207, Percent_Identity=28.9855072463768, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71992966, Length=238, Percent_Identity=27.3109243697479, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17531429, Length=243, Percent_Identity=27.9835390946502, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17531431, Length=243, Percent_Identity=27.9835390946502, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI71994009, Length=262, Percent_Identity=27.4809160305344, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6321054, Length=103, Percent_Identity=37.8640776699029, Blast_Score=62, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24652747, Length=248, Percent_Identity=30.241935483871, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI45551084, Length=248, Percent_Identity=30.241935483871, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24652751, Length=235, Percent_Identity=30.6382978723404, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI19922038, Length=231, Percent_Identity=31.1688311688312, Blast_Score=78, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012269
- InterPro:   IPR000425
- InterPro:   IPR022357 [H]

Pfam domain/function: PF00230 MIP [H]

EC number: NA

Molecular weight: Translated: 25557; Mature: 25557

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00221 MIP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYIAEFLGTFWLVLGGCGSAVFAAVVALSDADLSNGLGLGFLGVSLAFGLTVVTGAYA
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
FGHISGGHFNPAVSFGLWAAKRFPGHELLPYIVAQVLGGALAGLVILVVGSGNGALDLSG
HHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEECC
SNPLATNGFGSHSPGGYGLLAALITEIVMTFMFLMIILGSTDRRAPAGFAPVAIGLGLTL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
IHLISIPITNTSVNPARSTGVALFCGNVELIGQLWLFWVAPIFGAIAAGYAYSAFFSETK
HHHHHCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DTTGTGAPTIA
CCCCCCCCCCC
>Mature Secondary Structure
MKKYIAEFLGTFWLVLGGCGSAVFAAVVALSDADLSNGLGLGFLGVSLAFGLTVVTGAYA
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
FGHISGGHFNPAVSFGLWAAKRFPGHELLPYIVAQVLGGALAGLVILVVGSGNGALDLSG
HHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEECC
SNPLATNGFGSHSPGGYGLLAALITEIVMTFMFLMIILGSTDRRAPAGFAPVAIGLGLTL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
IHLISIPITNTSVNPARSTGVALFCGNVELIGQLWLFWVAPIFGAIAAGYAYSAFFSETK
HHHHHCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DTTGTGAPTIA
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O [Periplasm] [C]

Specific reaction: H2O [Periplasm] = H2O [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]