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The map label for this gene is pheA [H]

Identifier: 170078999

GI number: 170078999

Start: 2487763

End: 2488641

Strand: Direct

Name: pheA [H]

Synonym: SYNPCC7002_A2404

Alternate gene names: 170078999

Gene position: 2487763-2488641 (Clockwise)

Preceding gene: 170078998

Following gene: 170079002

Centisome position: 82.7

GC content: 53.58

Gene sequence:

>879_bases
ATGACCATAAAAATTGCTCACCTTGGGCCAGCGGGCACCAACGCCGAAGCAGCGGCACAGACCTATCAAGGGTGGTTGCA
GCGGGAACAATCTCCGGCTGTTGATCTAGTTCCCTGCCAGAGCATTGCCCAGAGTTTGTATGCCCTAGCCCACGATGAGG
TGCAATTAGCGGTGATCCCGGTGGAAAATTCAATTCAAGGGTCGGTGGCGATCGCCTTAGATTTGGTCTGGGAATTGCAT
CCTTTATCCATCTGCCATCAAATTATTCTGCCCATCCACCATGCCCTAATTTCCTTTGCCTCAGACTTTAGCGACATCAA
AGAAGTCCGCTCCCACCCCCAGGCCTTGGCCCAATGTCAGCGGTGGCTGGAAAAACATCTCCCCCATGCGGCCCTGATTG
AAGCAAATTCCACAACTGCAGTCCTGGGTAGCCTCAAGGACAATCCTCACCTGGGGGCGATCGCCGCGCCCCGGGCAGCA
CATCTTTACCACTTACCCATCGTGGTGGATGCCATTGGTGATTTTCCGCAAAATTGCACCCGGTTTTGGGTTTTAGGGAA
GGACGTCCAGACGGCTGGGGATGTGATTTCCCTTGCCTTTACCCTGCCCGCAAAAATTCCTGGGGTTCTCGTGAGTGCCC
TAGAGGTCTTTGCCCGCCGCAAAATTAACCTCAGCCGCATTGAATCGCGCCCCACGAAACGCTCCCTGGGAGAATATTTA
TTTTTTGTCGATCTCGATGGTTGTCTCACAAATCCCGATGTTCAAGCAGCCCTGACGGAACTCCAGACCCACACAGAAAT
TTTGAAAATCCTCGGCAACTACCGCACGATTCCTTTAGTTTCCCTGGGGGCAACGCCCGCCTCTGATCTCCAGGTGTAG

Upstream 100 bases:

>100_bases
GGCCAGTGGGGCGATGATCTGGTGGACGACGCGACCACGGCAGCGGCAACGCCCTTAAAAATTGGTAGGATTGGAAACAT
TCGCCAATTAATCGTCGGGT

Downstream 100 bases:

>100_bases
GATGCTCGTTTTTTGTTTGAAAAATAGGTGAGTTACGGACAAACGACCCCTTAGCTAGCGATGGAGGGAGAATTCACCGG
AGCTTCGGAAGAGACAGTCG

Product: prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MTIKIAHLGPAGTNAEAAAQTYQGWLQREQSPAVDLVPCQSIAQSLYALAHDEVQLAVIPVENSIQGSVAIALDLVWELH
PLSICHQIILPIHHALISFASDFSDIKEVRSHPQALAQCQRWLEKHLPHAALIEANSTTAVLGSLKDNPHLGAIAAPRAA
HLYHLPIVVDAIGDFPQNCTRFWVLGKDVQTAGDVISLAFTLPAKIPGVLVSALEVFARRKINLSRIESRPTKRSLGEYL
FFVDLDGCLTNPDVQAALTELQTHTEILKILGNYRTIPLVSLGATPASDLQV

Sequences:

>Translated_292_residues
MTIKIAHLGPAGTNAEAAAQTYQGWLQREQSPAVDLVPCQSIAQSLYALAHDEVQLAVIPVENSIQGSVAIALDLVWELH
PLSICHQIILPIHHALISFASDFSDIKEVRSHPQALAQCQRWLEKHLPHAALIEANSTTAVLGSLKDNPHLGAIAAPRAA
HLYHLPIVVDAIGDFPQNCTRFWVLGKDVQTAGDVISLAFTLPAKIPGVLVSALEVFARRKINLSRIESRPTKRSLGEYL
FFVDLDGCLTNPDVQAALTELQTHTEILKILGNYRTIPLVSLGATPASDLQV
>Mature_291_residues
TIKIAHLGPAGTNAEAAAQTYQGWLQREQSPAVDLVPCQSIAQSLYALAHDEVQLAVIPVENSIQGSVAIALDLVWELHP
LSICHQIILPIHHALISFASDFSDIKEVRSHPQALAQCQRWLEKHLPHAALIEANSTTAVLGSLKDNPHLGAIAAPRAAH
LYHLPIVVDAIGDFPQNCTRFWVLGKDVQTAGDVISLAFTLPAKIPGVLVSALEVFARRKINLSRIESRPTKRSLGEYLF
FVDLDGCLTNPDVQAALTELQTHTEILKILGNYRTIPLVSLGATPASDLQV

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=277, Percent_Identity=30.6859205776173, Blast_Score=119, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 31700; Mature: 31569

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00857 PREPHENATE_DEHYDR_1 ; PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKIAHLGPAGTNAEAAAQTYQGWLQREQSPAVDLVPCQSIAQSLYALAHDEVQLAVIP
CEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHCCCEEEEEEE
VENSIQGSVAIALDLVWELHPLSICHQIILPIHHALISFASDFSDIKEVRSHPQALAQCQ
CCCCCCCHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
RWLEKHLPHAALIEANSTTAVLGSLKDNPHLGAIAAPRAAHLYHLPIVVDAIGDFPQNCT
HHHHHHCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCHHHEEEHHHHEEHHHCCCCCCC
RFWVLGKDVQTAGDVISLAFTLPAKIPGVLVSALEVFARRKINLSRIESRPTKRSLGEYL
EEEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHCCEE
FFVDLDGCLTNPDVQAALTELQTHTEILKILGNYRTIPLVSLGATPASDLQV
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCC
>Mature Secondary Structure 
TIKIAHLGPAGTNAEAAAQTYQGWLQREQSPAVDLVPCQSIAQSLYALAHDEVQLAVIP
EEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHCCCEEEEEEE
VENSIQGSVAIALDLVWELHPLSICHQIILPIHHALISFASDFSDIKEVRSHPQALAQCQ
CCCCCCCHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
RWLEKHLPHAALIEANSTTAVLGSLKDNPHLGAIAAPRAAHLYHLPIVVDAIGDFPQNCT
HHHHHHCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCHHHEEEHHHHEEHHHCCCCCCC
RFWVLGKDVQTAGDVISLAFTLPAKIPGVLVSALEVFARRKINLSRIESRPTKRSLGEYL
EEEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHCCEE
FFVDLDGCLTNPDVQAALTELQTHTEILKILGNYRTIPLVSLGATPASDLQV
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]