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The map label for this gene is mco [H]

Identifier: 170078914

GI number: 170078914

Start: 2397690

End: 2399129

Strand: Reverse

Name: mco [H]

Synonym: SYNPCC7002_A2319

Alternate gene names: 170078914

Gene position: 2399129-2397690 (Counterclockwise)

Preceding gene: 170078915

Following gene: 170078913

Centisome position: 79.76

GC content: 52.08

Gene sequence:

>1440_bases
ATGGGCATTAAGCGGCGTGAGTTTCTCGGTTTAACGGCCTTGGGCGCAACGGGAGCATTGCTTTGGCAGGGGCGCAATCT
CCTCCGAAGCCGAAACTCTAGTCCTTTAGCCGCCCCCATACCAGAGATTTATCGTAGTGAAGGGGGTTCCCTGGAAATTA
ACCTCGAAGCCCGCTATGAAGATGTAATCCTTGGGGGAGAACCCACGCGCAACATGATGACCTACAACGGTCAAATCCCT
GGCCCCCGCTTGGAAGTTCGACCGGGCGATCGCCTAATTATTCACTTTAAAAATAGCCTCGATCAACCGACAAATCTACA
CTTCCACGGACTGCATCTTTCCCCAGAGGGCAACCAGGATAATGTATTCCTCCACATCGAACCAGGGGAAACTTTTCACT
ACGAACTGGAAATTCATCCCCAACAGCGGGCTGGCACTTACTGGTACCACCCCCACCACCATGGTTTTGTCGCCGAACAG
TTATTTCAGGGGTTAGCTGGGCTGATCGTTGTGCGGGGGGACTTGGATGAACTGCCAGAAATCCGTGCCGCCCAAGAGGA
ATTTTTTGTTCTCCAGGATTTTAACCGTGATCGCCCACCCCAAGGAATGATGGGCTCCCACATGAATTTGATGGCGGGTC
GAGAAGGGAATCTAATTACGGTCAATGGTCTTTTTCACCCAGAAATCGCCGTGACCAAAGACCTGGTGCGGCTGCGGTTA
CTGAATGCGTCCCCCTCGCGGTTCTATCGTCTCCAACTCTATGGCCAAAAGTTAATGCAAATTGCCGGAGATGATGGTGC
TTTTTCTCAACCCCTGGAGCGGGATGAATTACTTTTAACCCCAGGTCAACGGGCGGAGGTGCTCATCAAAACCCAGGATC
TACCGAAAACGCCGATCCATTTACTCAACCTTCCTTATCAACGCGCCCAGATAGGGATAATGGGACAGCAATACAACAAT
GCCACCGTGGCGATCGCCGATTTTACCCCCAGTGCTCCAACCTTCGCCCCGGTGCAAATTCCCGCCCAATTAATTCCCGT
TGAACCTTTACCGGAGCCGAGCCGAACCCGTCGTTTTACCCTGAACCATGGCATGGTACCAGGACAGGGAATGGCTTTTT
TGATCAATGGGGAAGCCTACCGGGATCAACCCCAAACCACCGTCCGCTTGAACGATGTGGAGGATTGGGAAATTGTGAAT
ACGGGCACAATGGATCACCCCTTCCATGTCCATGTGAATGGTTTTCAGGTGGTGAGCCGCAACGGTGTACCGGAAGAAAA
TATTGCCTGGGCAGATACGGTACTGGTGCGGGTCGGGGAAACGGTCAAAATCAGAATCGCTTTCCGGGATTTTGCAGGGA
AGACGGTCTACCATTGTCACATTCTCGACCATGAAGACCTTGGCATGATGGGCCAACTGGAAATTCTACCCGCTTCATAA

Upstream 100 bases:

>100_bases
AGCGGGCGATCGCCAACAGCCCTACCAAGTTTTGGCACTCCATGAAGATGGCACGACTTCTGTCTTTCAGGAATATCCAG
GTAATTAAGGGTTACAGACA

Downstream 100 bases:

>100_bases
AACGTGAAATTGCGGCCTTGACTCTCCAGTGCACTAGAGCTTTTATCCTGGAGCCAGCACTTGAATCATCGAGGAAAGTT
CGCCATGGAAACCCGCCAGT

Product: Type 3 multicopper oxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 479; Mature: 478

Protein sequence:

>479_residues
MGIKRREFLGLTALGATGALLWQGRNLLRSRNSSPLAAPIPEIYRSEGGSLEINLEARYEDVILGGEPTRNMMTYNGQIP
GPRLEVRPGDRLIIHFKNSLDQPTNLHFHGLHLSPEGNQDNVFLHIEPGETFHYELEIHPQQRAGTYWYHPHHHGFVAEQ
LFQGLAGLIVVRGDLDELPEIRAAQEEFFVLQDFNRDRPPQGMMGSHMNLMAGREGNLITVNGLFHPEIAVTKDLVRLRL
LNASPSRFYRLQLYGQKLMQIAGDDGAFSQPLERDELLLTPGQRAEVLIKTQDLPKTPIHLLNLPYQRAQIGIMGQQYNN
ATVAIADFTPSAPTFAPVQIPAQLIPVEPLPEPSRTRRFTLNHGMVPGQGMAFLINGEAYRDQPQTTVRLNDVEDWEIVN
TGTMDHPFHVHVNGFQVVSRNGVPEENIAWADTVLVRVGETVKIRIAFRDFAGKTVYHCHILDHEDLGMMGQLEILPAS

Sequences:

>Translated_479_residues
MGIKRREFLGLTALGATGALLWQGRNLLRSRNSSPLAAPIPEIYRSEGGSLEINLEARYEDVILGGEPTRNMMTYNGQIP
GPRLEVRPGDRLIIHFKNSLDQPTNLHFHGLHLSPEGNQDNVFLHIEPGETFHYELEIHPQQRAGTYWYHPHHHGFVAEQ
LFQGLAGLIVVRGDLDELPEIRAAQEEFFVLQDFNRDRPPQGMMGSHMNLMAGREGNLITVNGLFHPEIAVTKDLVRLRL
LNASPSRFYRLQLYGQKLMQIAGDDGAFSQPLERDELLLTPGQRAEVLIKTQDLPKTPIHLLNLPYQRAQIGIMGQQYNN
ATVAIADFTPSAPTFAPVQIPAQLIPVEPLPEPSRTRRFTLNHGMVPGQGMAFLINGEAYRDQPQTTVRLNDVEDWEIVN
TGTMDHPFHVHVNGFQVVSRNGVPEENIAWADTVLVRVGETVKIRIAFRDFAGKTVYHCHILDHEDLGMMGQLEILPAS
>Mature_478_residues
GIKRREFLGLTALGATGALLWQGRNLLRSRNSSPLAAPIPEIYRSEGGSLEINLEARYEDVILGGEPTRNMMTYNGQIPG
PRLEVRPGDRLIIHFKNSLDQPTNLHFHGLHLSPEGNQDNVFLHIEPGETFHYELEIHPQQRAGTYWYHPHHHGFVAEQL
FQGLAGLIVVRGDLDELPEIRAAQEEFFVLQDFNRDRPPQGMMGSHMNLMAGREGNLITVNGLFHPEIAVTKDLVRLRLL
NASPSRFYRLQLYGQKLMQIAGDDGAFSQPLERDELLLTPGQRAEVLIKTQDLPKTPIHLLNLPYQRAQIGIMGQQYNNA
TVAIADFTPSAPTFAPVQIPAQLIPVEPLPEPSRTRRFTLNHGMVPGQGMAFLINGEAYRDQPQTTVRLNDVEDWEIVNT
GTMDHPFHVHVNGFQVVSRNGVPEENIAWADTVLVRVGETVKIRIAFRDFAGKTVYHCHILDHEDLGMMGQLEILPAS

Specific function: May be involved in copper homeostasis and oxidative stress response [H]

COG id: COG2132

COG function: function code Q; Putative multicopper oxidases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multicopper oxidase family [H]

Homologues:

Organism=Escherichia coli, GI1786314, Length=530, Percent_Identity=27.7358490566038, Blast_Score=152, Evalue=5e-38,
Organism=Escherichia coli, GI1789394, Length=499, Percent_Identity=26.4529058116232, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6323703, Length=468, Percent_Identity=24.7863247863248, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6321067, Length=259, Percent_Identity=25.8687258687259, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001117
- InterPro:   IPR011706
- InterPro:   IPR011707
- InterPro:   IPR002355
- InterPro:   IPR008972 [H]

Pfam domain/function: PF00394 Cu-oxidase; PF07731 Cu-oxidase_2; PF07732 Cu-oxidase_3 [H]

EC number: NA

Molecular weight: Translated: 53830; Mature: 53699

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS00080 MULTICOPPER_OXIDASE2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIKRREFLGLTALGATGALLWQGRNLLRSRNSSPLAAPIPEIYRSEGGSLEINLEARYE
CCCCCCCEEEEEECCCCCEEEECCCHHHHCCCCCCCCCCCHHHHHCCCCEEEEEEEECEE
DVILGGEPTRNMMTYNGQIPGPRLEVRPGDRLIIHFKNSLDQPTNLHFHGLHLSPEGNQD
EEEECCCCCCCEEEECCCCCCCEEEECCCCEEEEEECCCCCCCCCEEEEEEEECCCCCCC
NVFLHIEPGETFHYELEIHPQQRAGTYWYHPHHHGFVAEQLFQGLAGLIVVRGDLDELPE
CEEEEEECCCEEEEEEEECCHHHCCEEEECCCCCCHHHHHHHHCCEEEEEEECCHHHCCH
IRAAQEEFFVLQDFNRDRPPQGMMGSHMNLMAGREGNLITVNGLFHPEIAVTKDLVRLRL
HHHCHHHEEEEECCCCCCCCCCCCCCCCEEEECCCCCEEEEECEECCCHHHHHHEEEEEE
LNASPSRFYRLQLYGQKLMQIAGDDGAFSQPLERDELLLTPGQRAEVLIKTQDLPKTPIH
ECCCCCCEEEEEEHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCEEEEEEECCCCCCCCE
LLNLPYQRAQIGIMGQQYNNATVAIADFTPSAPTFAPVQIPAQLIPVEPLPEPSRTRRFT
EECCCHHHEEEEEEEEECCCEEEEEEECCCCCCCEEEEECCCEEECCCCCCCCCCCEEEE
LNHGMVPGQGMAFLINGEAYRDQPQTTVRLNDVEDWEIVNTGTMDHPFHVHVNGFQVVSR
ECCCCCCCCCEEEEECCCHHCCCCCEEEEECCCCCEEEEECCCCCCCEEEEECCEEEEEC
NGVPEENIAWADTVLVRVGETVKIRIAFRDFAGKTVYHCHILDHEDLGMMGQLEILPAS
CCCCCCCCEEHEEEEEEECCEEEEEEEEECCCCCEEEEEEEECCCCCCCCEEEEEEECC
>Mature Secondary Structure 
GIKRREFLGLTALGATGALLWQGRNLLRSRNSSPLAAPIPEIYRSEGGSLEINLEARYE
CCCCCCEEEEEECCCCCEEEECCCHHHHCCCCCCCCCCCHHHHHCCCCEEEEEEEECEE
DVILGGEPTRNMMTYNGQIPGPRLEVRPGDRLIIHFKNSLDQPTNLHFHGLHLSPEGNQD
EEEECCCCCCCEEEECCCCCCCEEEECCCCEEEEEECCCCCCCCCEEEEEEEECCCCCCC
NVFLHIEPGETFHYELEIHPQQRAGTYWYHPHHHGFVAEQLFQGLAGLIVVRGDLDELPE
CEEEEEECCCEEEEEEEECCHHHCCEEEECCCCCCHHHHHHHHCCEEEEEEECCHHHCCH
IRAAQEEFFVLQDFNRDRPPQGMMGSHMNLMAGREGNLITVNGLFHPEIAVTKDLVRLRL
HHHCHHHEEEEECCCCCCCCCCCCCCCCEEEECCCCCEEEEECEECCCHHHHHHEEEEEE
LNASPSRFYRLQLYGQKLMQIAGDDGAFSQPLERDELLLTPGQRAEVLIKTQDLPKTPIH
ECCCCCCEEEEEEHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCEEEEEEECCCCCCCCE
LLNLPYQRAQIGIMGQQYNNATVAIADFTPSAPTFAPVQIPAQLIPVEPLPEPSRTRRFT
EECCCHHHEEEEEEEEECCCEEEEEEECCCCCCCEEEEECCCEEECCCCCCCCCCCEEEE
LNHGMVPGQGMAFLINGEAYRDQPQTTVRLNDVEDWEIVNTGTMDHPFHVHVNGFQVVSR
ECCCCCCCCCEEEEECCCHHCCCCCEEEEECCCCCEEEEECCCCCCCEEEEECCEEEEEC
NGVPEENIAWADTVLVRVGETVKIRIAFRDFAGKTVYHCHILDHEDLGMMGQLEILPAS
CCCCCCCCEEHEEEEEEECCEEEEEEEEECCCCCEEEEEEEECCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12950922 [H]