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The map label for this gene is hhoB [H]

Identifier: 170078898

GI number: 170078898

Start: 2383011

End: 2384207

Strand: Reverse

Name: hhoB [H]

Synonym: SYNPCC7002_A2303

Alternate gene names: 170078898

Gene position: 2384207-2383011 (Counterclockwise)

Preceding gene: 170078899

Following gene: 170078897

Centisome position: 79.26

GC content: 53.3

Gene sequence:

>1197_bases
ATGCTAAATCAATCTTTTCGTCAGTGGAGCCTCTACACGACTTTCCTTATCCTCGGGGGAAGCCTGGGGTTTTTGGGCCA
TGCCTATTGGTTCCAAAGACAGCTAAATGCATCTTTGCAGGCCTATGGTGAGTTTCGTCAATATGAGCAATCCCTGGCTG
CGCTGGATCTCAACCAAGACTCGGTAAATTTTATTGCTGAAGCGGTCAAAACCGTTGGGCCGACCGTCGTGCGCATTGAT
GCCCTAGATCAGACGGAGGCATCGGCATCGCCCACACCGTTATTTAAGAAGTTTTTTCAATTAGAAGAGGGCTTTCCCAC
CTTTGACGGCGATCGCCAACCCCAGGGCACGGGCTCCGGTTTTATTCTCAGTAGTGATGGCCAACTGGTGACCAATGCCC
ATGTGGTGGGAAATAGCTCTAAGGTAAAGGTGACTCTCAAAGATGGCCAGGTCTTTGAAGGACAAGTGATGGGTGTTGAT
GAGCTAACGGATATTGCCGTGATTAAAATCGACGCCACGGGGTTACCTACCGCAACATTAGGAAATGCGGCGAGTCTGAC
CCCAGGGGAATGGGCGATCGCCATTGGTAATCCCCTCGGTTTTGACAACAGTGTCACCGTCGGCATTATCAGTGCCCTCG
ACCGTCCCAGTGCCCAGGTCGGCATTCCGGACAAACGGGTACGTTTTATCCAAACCGATGCCGCCATTAACCCTGGTAAT
TCCGGTGGCCCCCTCCTCAATGTGCGGGGGGAAGTGATTGGCTTAAATACAGCGATTCGCGCCGATGGCCAAGGTCTGGG
ATTTGCCATTCCCATCGAAACCGCCCAACGCATTGCCCAACAACTCTTTACGGAGGGGAAAGCGACCCACCCTTACCTGG
GGATTCGAATGCTGGCATTGGACGGAGAAGGGAAAAATCGATTGCGGGAAACCCTGCCTGCCATGGCCCAGACGCTTGAT
TTAAATCAGGAAACAGGGGTGTTGGTGATTGAGGTTGCCCCAGATTCTCCGGCGGCGATCGCCAATATCCAGGTGGGAGA
TATCCTCAAGCAGGTGGGGGATCAACCCGTCCTGACCGCCTTTGATGTCCAGGATGTCGTAGAACGGAGTAGCATCGGTG
CTGATTTACCCATTGATCTCAAGCGCCGGGGCAAAATGCGGCAGTTAACCGTCCAGCCCACGGAGTTTCCGAGTTAG

Upstream 100 bases:

>100_bases
GGTTTTCTGGGCTGGTTAAAGTAGGGAATCAAGCAAGATTTTTGCCATAATTTTAAGGCAAGCTTGCGTTTATCTTTGCG
CCTCCAGTCTCCTCACACCC

Downstream 100 bases:

>100_bases
GCCAGGGTTATGGATCAATGGTGGGCCTTAATGATTGGCAACTCCCGGCTCCATTGGGCGACATTTACGGGGGATACCTT
GCAAACGGTACACCACACAG

Product: putative serine proteinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MLNQSFRQWSLYTTFLILGGSLGFLGHAYWFQRQLNASLQAYGEFRQYEQSLAALDLNQDSVNFIAEAVKTVGPTVVRID
ALDQTEASASPTPLFKKFFQLEEGFPTFDGDRQPQGTGSGFILSSDGQLVTNAHVVGNSSKVKVTLKDGQVFEGQVMGVD
ELTDIAVIKIDATGLPTATLGNAASLTPGEWAIAIGNPLGFDNSVTVGIISALDRPSAQVGIPDKRVRFIQTDAAINPGN
SGGPLLNVRGEVIGLNTAIRADGQGLGFAIPIETAQRIAQQLFTEGKATHPYLGIRMLALDGEGKNRLRETLPAMAQTLD
LNQETGVLVIEVAPDSPAAIANIQVGDILKQVGDQPVLTAFDVQDVVERSSIGADLPIDLKRRGKMRQLTVQPTEFPS

Sequences:

>Translated_398_residues
MLNQSFRQWSLYTTFLILGGSLGFLGHAYWFQRQLNASLQAYGEFRQYEQSLAALDLNQDSVNFIAEAVKTVGPTVVRID
ALDQTEASASPTPLFKKFFQLEEGFPTFDGDRQPQGTGSGFILSSDGQLVTNAHVVGNSSKVKVTLKDGQVFEGQVMGVD
ELTDIAVIKIDATGLPTATLGNAASLTPGEWAIAIGNPLGFDNSVTVGIISALDRPSAQVGIPDKRVRFIQTDAAINPGN
SGGPLLNVRGEVIGLNTAIRADGQGLGFAIPIETAQRIAQQLFTEGKATHPYLGIRMLALDGEGKNRLRETLPAMAQTLD
LNQETGVLVIEVAPDSPAAIANIQVGDILKQVGDQPVLTAFDVQDVVERSSIGADLPIDLKRRGKMRQLTVQPTEFPS
>Mature_398_residues
MLNQSFRQWSLYTTFLILGGSLGFLGHAYWFQRQLNASLQAYGEFRQYEQSLAALDLNQDSVNFIAEAVKTVGPTVVRID
ALDQTEASASPTPLFKKFFQLEEGFPTFDGDRQPQGTGSGFILSSDGQLVTNAHVVGNSSKVKVTLKDGQVFEGQVMGVD
ELTDIAVIKIDATGLPTATLGNAASLTPGEWAIAIGNPLGFDNSVTVGIISALDRPSAQVGIPDKRVRFIQTDAAINPGN
SGGPLLNVRGEVIGLNTAIRADGQGLGFAIPIETAQRIAQQLFTEGKATHPYLGIRMLALDGEGKNRLRETLPAMAQTLD
LNQETGVLVIEVAPDSPAAIANIQVGDILKQVGDQPVLTAFDVQDVVERSSIGADLPIDLKRRGKMRQLTVQPTEFPS

Specific function: A putative protease, its function overlaps that of the related putative proteases HtrA and HhoA [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=341, Percent_Identity=38.1231671554252, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI22129776, Length=367, Percent_Identity=35.4223433242507, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI7019477, Length=344, Percent_Identity=34.3023255813954, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI24308541, Length=316, Percent_Identity=32.2784810126582, Blast_Score=158, Evalue=7e-39,
Organism=Escherichia coli, GI1789630, Length=289, Percent_Identity=39.4463667820069, Blast_Score=180, Evalue=1e-46,
Organism=Escherichia coli, GI1789629, Length=334, Percent_Identity=34.4311377245509, Blast_Score=164, Evalue=9e-42,
Organism=Escherichia coli, GI1786356, Length=353, Percent_Identity=33.1444759206799, Blast_Score=162, Evalue=5e-41,
Organism=Drosophila melanogaster, GI24646839, Length=344, Percent_Identity=33.4302325581395, Blast_Score=173, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 42630; Mature: 42630

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNQSFRQWSLYTTFLILGGSLGFLGHAYWFQRQLNASLQAYGEFRQYEQSLAALDLNQD
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCC
SVNFIAEAVKTVGPTVVRIDALDQTEASASPTPLFKKFFQLEEGFPTFDGDRQPQGTGSG
HHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCE
FILSSDGQLVTNAHVVGNSSKVKVTLKDGQVFEGQVMGVDELTDIAVIKIDATGLPTATL
EEEECCCCEEEEEEEECCCCEEEEEEECCCEECCEEECCCCCCCEEEEEEECCCCCCCCC
GNAASLTPGEWAIAIGNPLGFDNSVTVGIISALDRPSAQVGIPDKRVRFIQTDAAINPGN
CCCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCCCCCCCCCCHHHEEEEEECCCCCCCC
SGGPLLNVRGEVIGLNTAIRADGQGLGFAIPIETAQRIAQQLFTEGKATHPYLGIRMLAL
CCCCEEEECCEEEEECEEEEECCCCCEEEEEHHHHHHHHHHHHHCCCCCCCEEEEEEEEE
DGEGKNRLRETLPAMAQTLDLNQETGVLVIEVAPDSPAAIANIQVGDILKQVGDQPVLTA
CCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEECCHHHHHHHHCCCCCEEE
FDVQDVVERSSIGADLPIDLKRRGKMRQLTVQPTEFPS
ECHHHHHHHHHCCCCCCCCHHHCCCEEEEEECCCCCCC
>Mature Secondary Structure
MLNQSFRQWSLYTTFLILGGSLGFLGHAYWFQRQLNASLQAYGEFRQYEQSLAALDLNQD
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCC
SVNFIAEAVKTVGPTVVRIDALDQTEASASPTPLFKKFFQLEEGFPTFDGDRQPQGTGSG
HHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCE
FILSSDGQLVTNAHVVGNSSKVKVTLKDGQVFEGQVMGVDELTDIAVIKIDATGLPTATL
EEEECCCCEEEEEEEECCCCEEEEEEECCCEECCEEECCCCCCCEEEEEEECCCCCCCCC
GNAASLTPGEWAIAIGNPLGFDNSVTVGIISALDRPSAQVGIPDKRVRFIQTDAAINPGN
CCCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCCCCCCCCCCHHHEEEEEECCCCCCCC
SGGPLLNVRGEVIGLNTAIRADGQGLGFAIPIETAQRIAQQLFTEGKATHPYLGIRMLAL
CCCCEEEECCEEEEECEEEEECCCCCEEEEEHHHHHHHHHHHHHCCCCCCCEEEEEEEEE
DGEGKNRLRETLPAMAQTLDLNQETGVLVIEVAPDSPAAIANIQVGDILKQVGDQPVLTA
CCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEECCHHHHHHHHCCCCCEEE
FDVQDVVERSSIGADLPIDLKRRGKMRQLTVQPTEFPS
ECHHHHHHHHHCCCCCCCCHHHCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]