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The map label for this gene is speE [H]

Identifier: 170078879

GI number: 170078879

Start: 2365331

End: 2366275

Strand: Reverse

Name: speE [H]

Synonym: SYNPCC7002_A2283

Alternate gene names: 170078879

Gene position: 2366275-2365331 (Counterclockwise)

Preceding gene: 170078883

Following gene: 170078876

Centisome position: 78.66

GC content: 52.59

Gene sequence:

>945_bases
ATGGCAGGTAGCGAAGTCAAAGCCGACTATTGGATTAACGAGTACATTACGCCCTGGGACATTTATAGCCACGGGATTAC
CAAGATTTTGGCCTATAAACAAACCCAATTTCAGGAGATGGCGATCGTTGAAAGCGGTGCCTATGGTAAAGCCCTGGTGC
TGGATGGAAAATGGCAGTCCTGTACCGGCGATGAATTTCTCTACCACGAACCCCTTGTTCATCCGGCGATGATTGCCCAT
GGTGCCCCGAAAAAGGTGTTGATCCTCGGTGCTGGGGAAGGGGCAACCGTGCGGGAAGTGCTGCGTTGGCAGTCCGTCGA
AAAGGTGATGATGGTGGATATCGACGGCGAAGTGGTGGAAGCCTGTAAGGAATTCTTGCCGGAGATGCACCAGGGGGTCT
TTGATGATCCGCGCCTCGACCTACGCATTGAAGATGCCTTCAAAATTTTAGAAACCACCACCGAAAAGTGGGATGTAATC
ATCTCTGACTTGTCTGATCCCATCGAAGAAGGCCCTTCCTTTAAGCTCTTTACCAAGGAATATTTCACCCAACTAAAGGA
TGTGCTCGCGCCCGGTGGCGTTGTGGCGGTGCAGGCAGGCCCTACGGCTCCGGCAAATTTGCGGCTCCACGCGCGGTTGG
TGAATACTCTCAAGGCAGTTTATGCCAACGTTTCCTCCTATTCGACACCCATTTCGAGCTACGGCTCCCCTTGGGGGTTT
GCAATCTGTACCGATGGGGATTTGAATCTGCGCCCCGACCCGGAAGCCGTGGATCAACTTTTGGCTGAGCAAACCACGGG
TGGCTTCAAGATTATCGATGGCTTAACGCTGTTGGGAATGTTGCAAACTTTCCGCCATGTCCGCGAGGCGATCGCCACCC
ACACCGAAGTCTTTACCCTAGCAGAACCGCCGAAATTCTTTGGGAAAGGTCACAAAGCTCAGTAA

Upstream 100 bases:

>100_bases
TTTTAAAAAGCTTACCGGACAAGGTTTTGGGGGGCGATCGCTAAAAAAATGAAAAAGTCTGCGATACTGGTATCCGGTCA
ATTGTCAGAAGAGAAAAATT

Downstream 100 bases:

>100_bases
GGTACTTTCCTCTTGAAACTCCTCTAACTCCCCTCAAGGGGCCACCCCTCTAGCTCCCCTCTAGGGGAGAGGGTTTTTGG
GATTTTTGGGCGGCACGGGC

Product: spermidine synthase

Products: NA

Alternate protein names: Putrescine aminopropyltransferase; PAPT; SPDSY [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MAGSEVKADYWINEYITPWDIYSHGITKILAYKQTQFQEMAIVESGAYGKALVLDGKWQSCTGDEFLYHEPLVHPAMIAH
GAPKKVLILGAGEGATVREVLRWQSVEKVMMVDIDGEVVEACKEFLPEMHQGVFDDPRLDLRIEDAFKILETTTEKWDVI
ISDLSDPIEEGPSFKLFTKEYFTQLKDVLAPGGVVAVQAGPTAPANLRLHARLVNTLKAVYANVSSYSTPISSYGSPWGF
AICTDGDLNLRPDPEAVDQLLAEQTTGGFKIIDGLTLLGMLQTFRHVREAIATHTEVFTLAEPPKFFGKGHKAQ

Sequences:

>Translated_314_residues
MAGSEVKADYWINEYITPWDIYSHGITKILAYKQTQFQEMAIVESGAYGKALVLDGKWQSCTGDEFLYHEPLVHPAMIAH
GAPKKVLILGAGEGATVREVLRWQSVEKVMMVDIDGEVVEACKEFLPEMHQGVFDDPRLDLRIEDAFKILETTTEKWDVI
ISDLSDPIEEGPSFKLFTKEYFTQLKDVLAPGGVVAVQAGPTAPANLRLHARLVNTLKAVYANVSSYSTPISSYGSPWGF
AICTDGDLNLRPDPEAVDQLLAEQTTGGFKIIDGLTLLGMLQTFRHVREAIATHTEVFTLAEPPKFFGKGHKAQ
>Mature_313_residues
AGSEVKADYWINEYITPWDIYSHGITKILAYKQTQFQEMAIVESGAYGKALVLDGKWQSCTGDEFLYHEPLVHPAMIAHG
APKKVLILGAGEGATVREVLRWQSVEKVMMVDIDGEVVEACKEFLPEMHQGVFDDPRLDLRIEDAFKILETTTEKWDVII
SDLSDPIEEGPSFKLFTKEYFTQLKDVLAPGGVVAVQAGPTAPANLRLHARLVNTLKAVYANVSSYSTPISSYGSPWGFA
ICTDGDLNLRPDPEAVDQLLAEQTTGGFKIIDGLTLLGMLQTFRHVREAIATHTEVFTLAEPPKFFGKGHKAQ

Specific function: Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor [H]

COG id: COG0421

COG function: function code E; Spermidine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the spermidine/spermine synthase family [H]

Homologues:

Organism=Homo sapiens, GI63253298, Length=237, Percent_Identity=32.4894514767932, Blast_Score=134, Evalue=1e-31,
Organism=Escherichia coli, GI1786312, Length=227, Percent_Identity=37.8854625550661, Blast_Score=165, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI25154106, Length=227, Percent_Identity=40.0881057268723, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI212645616, Length=234, Percent_Identity=37.1794871794872, Blast_Score=142, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6323175, Length=241, Percent_Identity=40.2489626556017, Blast_Score=178, Evalue=8e-46,
Organism=Saccharomyces cerevisiae, GI6325326, Length=259, Percent_Identity=35.5212355212355, Blast_Score=144, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24645443, Length=250, Percent_Identity=36.4, Blast_Score=144, Evalue=7e-35,
Organism=Drosophila melanogaster, GI21355941, Length=177, Percent_Identity=37.8531073446328, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24663238, Length=247, Percent_Identity=25.9109311740891, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001045 [H]

Pfam domain/function: PF01564 Spermine_synth [H]

EC number: =2.5.1.16 [H]

Molecular weight: Translated: 34745; Mature: 34614

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS51006 SPERMIDINE_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGSEVKADYWINEYITPWDIYSHGITKILAYKQTQFQEMAIVESGAYGKALVLDGKWQS
CCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCC
CTGDEFLYHEPLVHPAMIAHGAPKKVLILGAGEGATVREVLRWQSVEKVMMVDIDGEVVE
CCCCCCCCCCCCCCHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCHHHH
ACKEFLPEMHQGVFDDPRLDLRIEDAFKILETTTEKWDVIISDLSDPIEEGPSFKLFTKE
HHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCEEEEHHH
YFTQLKDVLAPGGVVAVQAGPTAPANLRLHARLVNTLKAVYANVSSYSTPISSYGSPWGF
HHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCE
AICTDGDLNLRPDPEAVDQLLAEQTTGGFKIIDGLTLLGMLQTFRHVREAIATHTEVFTL
EEEECCCCCCCCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
AEPPKFFGKGHKAQ
CCCHHHHCCCCCCC
>Mature Secondary Structure 
AGSEVKADYWINEYITPWDIYSHGITKILAYKQTQFQEMAIVESGAYGKALVLDGKWQS
CCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCC
CTGDEFLYHEPLVHPAMIAHGAPKKVLILGAGEGATVREVLRWQSVEKVMMVDIDGEVVE
CCCCCCCCCCCCCCHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCHHHH
ACKEFLPEMHQGVFDDPRLDLRIEDAFKILETTTEKWDVIISDLSDPIEEGPSFKLFTKE
HHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCEEEEHHH
YFTQLKDVLAPGGVVAVQAGPTAPANLRLHARLVNTLKAVYANVSSYSTPISSYGSPWGF
HHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCE
AICTDGDLNLRPDPEAVDQLLAEQTTGGFKIIDGLTLLGMLQTFRHVREAIATHTEVFTL
EEEECCCCCCCCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
AEPPKFFGKGHKAQ
CCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA