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The map label for this gene is gcvT

Identifier: 170078310

GI number: 170078310

Start: 1786718

End: 1787809

Strand: Reverse

Name: gcvT

Synonym: SYNPCC7002_A1703

Alternate gene names: 170078310

Gene position: 1787809-1786718 (Counterclockwise)

Preceding gene: 170078311

Following gene: 170078301

Centisome position: 59.43

GC content: 52.75

Gene sequence:

>1092_bases
ATGACTTTACAGCGCACGCCCCTCCATGACCTCGCCATTGCAGCGGGTGCCAAATTTGTACCGTTTTCCGGTTGGGAGAT
GGCCGTGCAATACAAAGGCCTAAAGGTGGAGCATCAGGCGGTGCGCACAGAGGTGGGAATGTTTGATATTTCCCACATGG
GCAAGTTTCAGTTGGCTGGGGAAAACCTCATTGCAGCCATGCAAAAACTGGTGCCTTCAAATCTGGCACGACTTGCTCCC
GGTCAAGCGCAATACACAGTGCTACTCAATGACCACGGCGGCATCATCGATGATGTGATCTATTATCACCAGGGCGATCG
CCAGGGCTTTTTGATTGTGAATGCGGCCACCACCCAGAAGGATTGGGACTGGTTAACGCACCATTTGACAGCGCAGGGGA
TCACTTTAACCGATGTCTCCCAAGAAAATATCTTGCTGGCGATCCAAGGCCCCCAGGCGGAGAAAGCCTTGCAACCTGTT
GTGGAAAATTTAGATTTGGCGACCCTAAAGCTGTTTAACCACGGCCAAGGACAAATTTTCGGGGAAACGGCTTTTATTGC
CCGGACTGGCTACACTGGCGAAGATGGCTTTGAGGTGATGGTCGCGCCGACAGCAGGGAAAAAACTTTGGAGCGCTTTAA
TCGATGCGGGGGTGATGCCCTGTGGTTTGGGAGCACGGGATACGCTGCGACTGGAGGCCGGGTTACACCTCTATGGTCAG
GACATGGACGACGACACAACCCCTTTGGAAGCGGGTTTGGGGTGGCTGATCCACTGGCAAGAAAAAGATGCGTTTATCGC
TAAGGATATTTTGCAGACCCAAAAAGCAGCAGGTGTTCAACGGCGTTTGGTGGGCCTAGAGATGCAGGGGCGCGGTATCG
CCCGCCATGACTATTCTGTTCTCGTCAATGGTGAAGCAGTGGGCCTTGTGACCAGTGGTACGATGTCCCCCACCCTCGAA
AAGGCGATCGCCTTAGCTTATCTCCCGTTGGAATTTAGCAAAGTAGGTCAAGCTGTCACCGTAGAAATCCGCGGGAAACA
GTACCCAGCCCAGGTGGTGAAAAAACCTTTTTATCGTGCCAGCAAAAAATAG

Upstream 100 bases:

>100_bases
TTGTTCAAGGTCGTCCACCCGTGCCAGTGGCCCCAGACGATGAGATTCCGTTCTGAGAACCTCGTATCATTGATGGTGAT
GTCTCTTGGATGAAGCCCCT

Downstream 100 bases:

>100_bases
CTGATCAGTTAGCGATATTTTTTGAGCAGATTTTCAGAATCCTGGGGGTCAAGGCCATCACCAAGGGCAGTCATGGCCCA
GCCATTTTCCTCCCGACGTA

Product: glycine cleavage system aminomethyltransferase T

Products: NA

Alternate protein names: Glycine cleavage system T protein

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MTLQRTPLHDLAIAAGAKFVPFSGWEMAVQYKGLKVEHQAVRTEVGMFDISHMGKFQLAGENLIAAMQKLVPSNLARLAP
GQAQYTVLLNDHGGIIDDVIYYHQGDRQGFLIVNAATTQKDWDWLTHHLTAQGITLTDVSQENILLAIQGPQAEKALQPV
VENLDLATLKLFNHGQGQIFGETAFIARTGYTGEDGFEVMVAPTAGKKLWSALIDAGVMPCGLGARDTLRLEAGLHLYGQ
DMDDDTTPLEAGLGWLIHWQEKDAFIAKDILQTQKAAGVQRRLVGLEMQGRGIARHDYSVLVNGEAVGLVTSGTMSPTLE
KAIALAYLPLEFSKVGQAVTVEIRGKQYPAQVVKKPFYRASKK

Sequences:

>Translated_363_residues
MTLQRTPLHDLAIAAGAKFVPFSGWEMAVQYKGLKVEHQAVRTEVGMFDISHMGKFQLAGENLIAAMQKLVPSNLARLAP
GQAQYTVLLNDHGGIIDDVIYYHQGDRQGFLIVNAATTQKDWDWLTHHLTAQGITLTDVSQENILLAIQGPQAEKALQPV
VENLDLATLKLFNHGQGQIFGETAFIARTGYTGEDGFEVMVAPTAGKKLWSALIDAGVMPCGLGARDTLRLEAGLHLYGQ
DMDDDTTPLEAGLGWLIHWQEKDAFIAKDILQTQKAAGVQRRLVGLEMQGRGIARHDYSVLVNGEAVGLVTSGTMSPTLE
KAIALAYLPLEFSKVGQAVTVEIRGKQYPAQVVKKPFYRASKK
>Mature_362_residues
TLQRTPLHDLAIAAGAKFVPFSGWEMAVQYKGLKVEHQAVRTEVGMFDISHMGKFQLAGENLIAAMQKLVPSNLARLAPG
QAQYTVLLNDHGGIIDDVIYYHQGDRQGFLIVNAATTQKDWDWLTHHLTAQGITLTDVSQENILLAIQGPQAEKALQPVV
ENLDLATLKLFNHGQGQIFGETAFIARTGYTGEDGFEVMVAPTAGKKLWSALIDAGVMPCGLGARDTLRLEAGLHLYGQD
MDDDTTPLEAGLGWLIHWQEKDAFIAKDILQTQKAAGVQRRLVGLEMQGRGIARHDYSVLVNGEAVGLVTSGTMSPTLEK
AIALAYLPLEFSKVGQAVTVEIRGKQYPAQVVKKPFYRASKK

Specific function: The glycine cleavage system catalyzes the degradation of glycine

COG id: COG0404

COG function: function code E; Glycine cleavage system T protein (aminomethyltransferase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family

Homologues:

Organism=Homo sapiens, GI44662838, Length=363, Percent_Identity=37.1900826446281, Blast_Score=231, Evalue=9e-61,
Organism=Homo sapiens, GI257796258, Length=349, Percent_Identity=36.3896848137536, Blast_Score=218, Evalue=7e-57,
Organism=Homo sapiens, GI257796254, Length=360, Percent_Identity=35, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI257796256, Length=308, Percent_Identity=36.3636363636364, Blast_Score=184, Evalue=8e-47,
Organism=Homo sapiens, GI24797151, Length=329, Percent_Identity=30.0911854103343, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI197927446, Length=359, Percent_Identity=28.133704735376, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI21361378, Length=359, Percent_Identity=28.133704735376, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI194306651, Length=366, Percent_Identity=24.0437158469945, Blast_Score=89, Evalue=7e-18,
Organism=Escherichia coli, GI1789272, Length=375, Percent_Identity=40.5333333333333, Blast_Score=262, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI17560118, Length=357, Percent_Identity=35.0140056022409, Blast_Score=204, Evalue=6e-53,
Organism=Caenorhabditis elegans, GI71994045, Length=372, Percent_Identity=24.7311827956989, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI71994052, Length=372, Percent_Identity=24.7311827956989, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI32563613, Length=344, Percent_Identity=22.9651162790698, Blast_Score=88, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6320222, Length=379, Percent_Identity=36.6754617414248, Blast_Score=208, Evalue=1e-54,
Organism=Drosophila melanogaster, GI20129441, Length=376, Percent_Identity=35.3723404255319, Blast_Score=211, Evalue=7e-55,
Organism=Drosophila melanogaster, GI20130091, Length=349, Percent_Identity=28.9398280802292, Blast_Score=111, Evalue=8e-25,
Organism=Drosophila melanogaster, GI28571104, Length=326, Percent_Identity=23.9263803680982, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): GCST_SYNP2 (B1XP99)

Other databases:

- EMBL:   CP000951
- RefSeq:   YP_001734948.1
- ProteinModelPortal:   B1XP99
- SMR:   B1XP99
- GeneID:   6057059
- GenomeReviews:   CP000951_GR
- KEGG:   syp:SYNPCC7002_A1703
- HOGENOM:   HBG299834
- OMA:   KALYGGM
- ProtClustDB:   PRK00389
- GO:   GO:0005737
- HAMAP:   MF_00259
- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006223
- InterPro:   IPR022903
- PIRSF:   PIRSF006487
- TIGRFAMs:   TIGR00528

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C

EC number: =2.1.2.10

Molecular weight: Translated: 39644; Mature: 39513

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLQRTPLHDLAIAAGAKFVPFSGWEMAVQYKGLKVEHQAVRTEVGMFDISHMGKFQLAG
CCCCCCCCHHHHHHCCCEEECCCCCEEEEEECCCEEHHHHHHHHHCEEECCCCCEEEECC
ENLIAAMQKLVPSNLARLAPGQAQYTVLLNDHGGIIDDVIYYHQGDRQGFLIVNAATTQK
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHEEEEECCCCCEEEEEEECCCCC
DWDWLTHHLTAQGITLTDVSQENILLAIQGPQAEKALQPVVENLDLATLKLFNHGQGQIF
CHHHHHHHHEECCEEEEECCCCCEEEEEECCCHHHHHHHHHHCCCEEEEEEEECCCCEEE
GETAFIARTGYTGEDGFEVMVAPTAGKKLWSALIDAGVMPCGLGARDTLRLEAGLHLYGQ
ECEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEECC
DMDDDTTPLEAGLGWLIHWQEKDAFIAKDILQTQKAAGVQRRLVGLEMQGRGIARHDYSV
CCCCCCCCHHHCCEEEEEEECCCHHHHHHHHHHHHHHCHHHHHEEEEECCCCEEECCCEE
LVNGEAVGLVTSGTMSPTLEKAIALAYLPLEFSKVGQAVTVEIRGKQYPAQVVKKPFYRA
EECCCEEEEEECCCCCHHHHHHHEEEEECCCHHHCCCEEEEEECCCCCCHHHHHCHHHHC
SKK
CCC
>Mature Secondary Structure 
TLQRTPLHDLAIAAGAKFVPFSGWEMAVQYKGLKVEHQAVRTEVGMFDISHMGKFQLAG
CCCCCCCHHHHHHCCCEEECCCCCEEEEEECCCEEHHHHHHHHHCEEECCCCCEEEECC
ENLIAAMQKLVPSNLARLAPGQAQYTVLLNDHGGIIDDVIYYHQGDRQGFLIVNAATTQK
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHEEEEECCCCCEEEEEEECCCCC
DWDWLTHHLTAQGITLTDVSQENILLAIQGPQAEKALQPVVENLDLATLKLFNHGQGQIF
CHHHHHHHHEECCEEEEECCCCCEEEEEECCCHHHHHHHHHHCCCEEEEEEEECCCCEEE
GETAFIARTGYTGEDGFEVMVAPTAGKKLWSALIDAGVMPCGLGARDTLRLEAGLHLYGQ
ECEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEECC
DMDDDTTPLEAGLGWLIHWQEKDAFIAKDILQTQKAAGVQRRLVGLEMQGRGIARHDYSV
CCCCCCCCHHHCCEEEEEEECCCHHHHHHHHHHHHHHCHHHHHEEEEECCCCEEECCCEE
LVNGEAVGLVTSGTMSPTLEKAIALAYLPLEFSKVGQAVTVEIRGKQYPAQVVKKPFYRA
EECCCEEEEEECCCCCHHHHHHHEEEEECCCHHHCCCEEEEEECCCCCCHHHHHCHHHHC
SKK
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA