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The map label for this gene is purL [H]

Identifier: 170078274

GI number: 170078274

Start: 1748971

End: 1751262

Strand: Reverse

Name: purL [H]

Synonym: SYNPCC7002_A1667

Alternate gene names: 170078274

Gene position: 1751262-1748971 (Counterclockwise)

Preceding gene: 170078275

Following gene: 170078273

Centisome position: 58.22

GC content: 50.87

Gene sequence:

>2292_bases
ATGACCACTTGCCCCTTCACCCCCGAAGAAATTGCATCTGAAGGCATCAAACCCGAAGAATACGAAGAAATTGTGAGCCG
TCTCGGTCGCCATCCCAACAAGGCTGAACTGGGGATGTTTGGCGTGATGTGGTCGGAACATTGTTGTTATAAGAATTCCC
GCCCATTGCTGTCTGGTTTCCCCACGAAAGGCGATCGCGTCCTCGTCGGCCCCGGTGAAAATGCGGGCGTGGTCGATATG
GGGGATGGTCTGCACCTCGCCTTTAAGATCGAATCCCATAACCACCCATCGGCGATCGAACCCTTCCAAGGGGCAGCAAC
CGGGGTCGGTGGTATTCTCCGCGATATCTTTACGATGGGGGCGCGTCCCATTGCCTTGTTAAATTCTCTACGCTTCGGCA
CCCTCGATAATGCCCAAACTCGCCGCATTTTTCAGGGAGTTGTGGAAGGGATTAGCCATTATGGAAACTGTGTGGGTGTG
CCAACGGTGGGCGGTGAAGTCTATTTCGATAAAGCCTATGCCGGAAATCCCCTCGTCAATGCGATGGCGTTGGGCTTGAT
GGAAACCGAGGAAATTATTAAATCGGGAGCCTATGGCATTGGTAATCCCGTTCTCTATGTCGGCTCCACCACCGGACGGG
ATGGCATGGGGGGCGCAAGTTTTGCCAGTGCGGAATTGACCGATGAATCTATGGACGATCGCCCTGCGGTGCAAGTGGGT
GATCCCTTTACCGAAAAATCCCTGATTGAAGCCTGTCTCGAAGCCTTTAAAACGGGGGCAGTGGCAGCGGCGCAGGATAT
GGGGGCGGCGGGTTTAACCTGTTCGACAGCGGAAATGGCGGCTAAAGGTGGGGTCGGTGTGTTGCTCGATCTCGATAAAA
TTCCGGTGCGAGAAACGGGCATGGTTCCCTATGAATATTTACTCTCGGAATCCCAAGAACGGATGCTTTTTGTTGCCCAC
CAAGGACGGGAACAGGAGTTAATTGATATCTTCCATCGTTGGGGTTTACAGGCAGTTGTTGCGGGGGAAGTGATTGCGGA
ACCCATCGTGAAAATCATGTTTAAGGGTGAAGTAGCCGCAGAAGTTCAAGCAACTGCGCTATCAGATAATACGCCCATTT
ATCATCGGGAATTGATGGCAGAAGCTCCCAAATATGCACAAACGGCTTGGGCTTGGTCGGTGGATTCTTTGCCGAATTGT
GATGGGAATGGCATCGCTGAAAAATCTTGGAATGAGATTTTATTAACCCTGTTAGATGTGCCAACTATTGCGTCTAAAAA
ATGGATTTATCGCCAGTACGATCATCAAGTACAAAACAATACGGTGATCTTCCCCGGTGGCGCAGATGCCGCTGTGGTGC
GGGTTCGTCCGGTCAATGGTAAGCCCGATGCGTCAACAATTGGTGTGGCGGCTTGTACCGATTGTAATCCCCGTTATGTC
TATTTAAATCCGTTGGAAGGGGCAAAGGCGGCGGTCGCTGAAGCAGCGAGAAATTTAAGTTGTGTCGGTGCTGAACCCTT
GGCAATTACAAACAATTTAAACTTTGGTAGTCCTGAAAAACCTGTGGGTTATTGGCAGTTGGCAAATGCTTGCAAAGGGA
TTGCTGAAGCTTGCCGAGAATTGGACACTCCCGTTACTGGTGGTAATGTTTCCCTCTACAATGAAACCCTTGATAGTGAT
GGCAAACCGACCCCCATTTATCCGACTCCTGTGATCGGGATGGTGGGACGAGTTGAACATATTAATCAGGTCTGTGGTTT
AGCCTTCCAAAATGCTGGGGATAAGGTCTATCTCCTTGGTACTCAGGCAACAACAACCCTCGGCGGTTCGGAATATCTAA
ATACGATTCATAACACCGTCGCGGGTATTCCGCCCCAAGTGGATTTTGAGCTAGAGAAAGCCGTCCAGAAAACTGTACGG
GAGGCGATCGCCGCTGGCTTGTTAAACTCTGCCCATGACCTTGCGGAGGGTGGTTTAGCCGTTGCCCTTGCGGAATGTTG
TATCGGTGGGAAGCTCGGCGCAACCGTTGAAATTACTGGCACTGACCGTCTCGATGCCATCCTATTTGGCGAAACCTGCG
GCAAAATTATTGTCTCTGTTGCTCCCGACAAACAAGCTCAATTTGAAGCCCATCTGACGCAATCCTTGGCGGACAATTGG
CAGGTGATCGGCTCTGTGAGCAACACCAATCAGTTACAAATTACCGTCAACAATCAGGCTGTAATCGCGGTTTCTGTCGA
GGATATGACCACCAACTGGAGTGAGGCGATCGCCCGTCGTTTACATCCGTAA

Upstream 100 bases:

>100_bases
CAAGCACAGATTCCCGTAGAAGACTTCCTTAATCTTTAACTGCCGCTCGTCTCCTGAAGCCTTACAATAACGCTGTTACA
GAAAGAATCGACGTAAAACT

Downstream 100 bases:

>100_bases
TCTAATTAACTGATTACAATAGAAAGTACAAATCCAGTGGGTAAGGCTAATGACAACAATGACCCTTGCGCTAGAACCCG
TTTTCACCTTAAGCAATGAA

Product: phosphoribosylformylglycinamidine synthase II

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase II; FGAM synthase II [H]

Number of amino acids: Translated: 763; Mature: 762

Protein sequence:

>763_residues
MTTCPFTPEEIASEGIKPEEYEEIVSRLGRHPNKAELGMFGVMWSEHCCYKNSRPLLSGFPTKGDRVLVGPGENAGVVDM
GDGLHLAFKIESHNHPSAIEPFQGAATGVGGILRDIFTMGARPIALLNSLRFGTLDNAQTRRIFQGVVEGISHYGNCVGV
PTVGGEVYFDKAYAGNPLVNAMALGLMETEEIIKSGAYGIGNPVLYVGSTTGRDGMGGASFASAELTDESMDDRPAVQVG
DPFTEKSLIEACLEAFKTGAVAAAQDMGAAGLTCSTAEMAAKGGVGVLLDLDKIPVRETGMVPYEYLLSESQERMLFVAH
QGREQELIDIFHRWGLQAVVAGEVIAEPIVKIMFKGEVAAEVQATALSDNTPIYHRELMAEAPKYAQTAWAWSVDSLPNC
DGNGIAEKSWNEILLTLLDVPTIASKKWIYRQYDHQVQNNTVIFPGGADAAVVRVRPVNGKPDASTIGVAACTDCNPRYV
YLNPLEGAKAAVAEAARNLSCVGAEPLAITNNLNFGSPEKPVGYWQLANACKGIAEACRELDTPVTGGNVSLYNETLDSD
GKPTPIYPTPVIGMVGRVEHINQVCGLAFQNAGDKVYLLGTQATTTLGGSEYLNTIHNTVAGIPPQVDFELEKAVQKTVR
EAIAAGLLNSAHDLAEGGLAVALAECCIGGKLGATVEITGTDRLDAILFGETCGKIIVSVAPDKQAQFEAHLTQSLADNW
QVIGSVSNTNQLQITVNNQAVIAVSVEDMTTNWSEAIARRLHP

Sequences:

>Translated_763_residues
MTTCPFTPEEIASEGIKPEEYEEIVSRLGRHPNKAELGMFGVMWSEHCCYKNSRPLLSGFPTKGDRVLVGPGENAGVVDM
GDGLHLAFKIESHNHPSAIEPFQGAATGVGGILRDIFTMGARPIALLNSLRFGTLDNAQTRRIFQGVVEGISHYGNCVGV
PTVGGEVYFDKAYAGNPLVNAMALGLMETEEIIKSGAYGIGNPVLYVGSTTGRDGMGGASFASAELTDESMDDRPAVQVG
DPFTEKSLIEACLEAFKTGAVAAAQDMGAAGLTCSTAEMAAKGGVGVLLDLDKIPVRETGMVPYEYLLSESQERMLFVAH
QGREQELIDIFHRWGLQAVVAGEVIAEPIVKIMFKGEVAAEVQATALSDNTPIYHRELMAEAPKYAQTAWAWSVDSLPNC
DGNGIAEKSWNEILLTLLDVPTIASKKWIYRQYDHQVQNNTVIFPGGADAAVVRVRPVNGKPDASTIGVAACTDCNPRYV
YLNPLEGAKAAVAEAARNLSCVGAEPLAITNNLNFGSPEKPVGYWQLANACKGIAEACRELDTPVTGGNVSLYNETLDSD
GKPTPIYPTPVIGMVGRVEHINQVCGLAFQNAGDKVYLLGTQATTTLGGSEYLNTIHNTVAGIPPQVDFELEKAVQKTVR
EAIAAGLLNSAHDLAEGGLAVALAECCIGGKLGATVEITGTDRLDAILFGETCGKIIVSVAPDKQAQFEAHLTQSLADNW
QVIGSVSNTNQLQITVNNQAVIAVSVEDMTTNWSEAIARRLHP
>Mature_762_residues
TTCPFTPEEIASEGIKPEEYEEIVSRLGRHPNKAELGMFGVMWSEHCCYKNSRPLLSGFPTKGDRVLVGPGENAGVVDMG
DGLHLAFKIESHNHPSAIEPFQGAATGVGGILRDIFTMGARPIALLNSLRFGTLDNAQTRRIFQGVVEGISHYGNCVGVP
TVGGEVYFDKAYAGNPLVNAMALGLMETEEIIKSGAYGIGNPVLYVGSTTGRDGMGGASFASAELTDESMDDRPAVQVGD
PFTEKSLIEACLEAFKTGAVAAAQDMGAAGLTCSTAEMAAKGGVGVLLDLDKIPVRETGMVPYEYLLSESQERMLFVAHQ
GREQELIDIFHRWGLQAVVAGEVIAEPIVKIMFKGEVAAEVQATALSDNTPIYHRELMAEAPKYAQTAWAWSVDSLPNCD
GNGIAEKSWNEILLTLLDVPTIASKKWIYRQYDHQVQNNTVIFPGGADAAVVRVRPVNGKPDASTIGVAACTDCNPRYVY
LNPLEGAKAAVAEAARNLSCVGAEPLAITNNLNFGSPEKPVGYWQLANACKGIAEACRELDTPVTGGNVSLYNETLDSDG
KPTPIYPTPVIGMVGRVEHINQVCGLAFQNAGDKVYLLGTQATTTLGGSEYLNTIHNTVAGIPPQVDFELEKAVQKTVRE
AIAAGLLNSAHDLAEGGLAVALAECCIGGKLGATVEITGTDRLDAILFGETCGKIIVSVAPDKQAQFEAHLTQSLADNWQ
VIGSVSNTNQLQITVNNQAVIAVSVEDMTTNWSEAIARRLHP

Specific function: Unknown

COG id: COG0046

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGAMS family [H]

Homologues:

Organism=Homo sapiens, GI31657129, Length=751, Percent_Identity=23.0359520639148, Blast_Score=94, Evalue=6e-19,
Organism=Escherichia coli, GI48994899, Length=825, Percent_Identity=24.8484848484848, Blast_Score=148, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17553022, Length=768, Percent_Identity=24.0885416666667, Blast_Score=114, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6321498, Length=828, Percent_Identity=22.5845410628019, Blast_Score=114, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24582111, Length=689, Percent_Identity=23.6574746008708, Blast_Score=98, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24582109, Length=689, Percent_Identity=23.6574746008708, Blast_Score=98, Evalue=3e-20,
Organism=Drosophila melanogaster, GI17137292, Length=689, Percent_Identity=23.6574746008708, Blast_Score=98, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR010074
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 81238; Mature: 81107

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTCPFTPEEIASEGIKPEEYEEIVSRLGRHPNKAELGMFGVMWSEHCCYKNSRPLLSGF
CCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHCCCCCCCCCCCCC
PTKGDRVLVGPGENAGVVDMGDGLHLAFKIESHNHPSAIEPFQGAATGVGGILRDIFTMG
CCCCCEEEECCCCCCCEEECCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCC
ARPIALLNSLRFGTLDNAQTRRIFQGVVEGISHYGNCVGVPTVGGEVYFDKAYAGNPLVN
CCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEECCCCCCHHHH
AMALGLMETEEIIKSGAYGIGNPVLYVGSTTGRDGMGGASFASAELTDESMDDRPAVQVG
HHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEECC
DPFTEKSLIEACLEAFKTGAVAAAQDMGAAGLTCSTAEMAAKGGVGVLLDLDKIPVRETG
CCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCEECHHHHHHCCCCEEEEECCCCCCCCCC
MVPYEYLLSESQERMLFVAHQGREQELIDIFHRWGLQAVVAGEVIAEPIVKIMFKGEVAA
CCCHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHCCCCHHH
EVQATALSDNTPIYHRELMAEAPKYAQTAWAWSVDSLPNCDGNGIAEKSWNEILLTLLDV
EEEEEEECCCCCHHHHHHHHCCCHHHHHHEEEECCCCCCCCCCCCCCCHHHHHHHHHHCC
PTIASKKWIYRQYDHQVQNNTVIFPGGADAAVVRVRPVNGKPDASTIGVAACTDCNPRYV
CCCCCCHHHHHHHHHHHCCCEEEEECCCCEEEEEEEECCCCCCCCCEEEEEECCCCCCEE
YLNPLEGAKAAVAEAARNLSCVGAEPLAITNNLNFGSPEKPVGYWQLANACKGIAEACRE
EECCCCCHHHHHHHHHHCCEECCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LDTPVTGGNVSLYNETLDSDGKPTPIYPTPVIGMVGRVEHINQVCGLAFQNAGDKVYLLG
HCCCCCCCCEEEEEHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
TQATTTLGGSEYLNTIHNTVAGIPPQVDFELEKAVQKTVREAIAAGLLNSAHDLAEGGLA
CCCEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
VALAECCIGGKLGATVEITGTDRLDAILFGETCGKIIVSVAPDKQAQFEAHLTQSLADNW
HHHHHHHCCCCCCCEEEEECCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHCCE
QVIGSVSNTNQLQITVNNQAVIAVSVEDMTTNWSEAIARRLHP
EEEEECCCCCEEEEEECCCEEEEEEECCCCCCHHHHHHHHCCC
>Mature Secondary Structure 
TTCPFTPEEIASEGIKPEEYEEIVSRLGRHPNKAELGMFGVMWSEHCCYKNSRPLLSGF
CCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHCCCCCCCCCCCCC
PTKGDRVLVGPGENAGVVDMGDGLHLAFKIESHNHPSAIEPFQGAATGVGGILRDIFTMG
CCCCCEEEECCCCCCCEEECCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCC
ARPIALLNSLRFGTLDNAQTRRIFQGVVEGISHYGNCVGVPTVGGEVYFDKAYAGNPLVN
CCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEECCCCCCHHHH
AMALGLMETEEIIKSGAYGIGNPVLYVGSTTGRDGMGGASFASAELTDESMDDRPAVQVG
HHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEECC
DPFTEKSLIEACLEAFKTGAVAAAQDMGAAGLTCSTAEMAAKGGVGVLLDLDKIPVRETG
CCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCEECHHHHHHCCCCEEEEECCCCCCCCCC
MVPYEYLLSESQERMLFVAHQGREQELIDIFHRWGLQAVVAGEVIAEPIVKIMFKGEVAA
CCCHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHCCCCHHH
EVQATALSDNTPIYHRELMAEAPKYAQTAWAWSVDSLPNCDGNGIAEKSWNEILLTLLDV
EEEEEEECCCCCHHHHHHHHCCCHHHHHHEEEECCCCCCCCCCCCCCCHHHHHHHHHHCC
PTIASKKWIYRQYDHQVQNNTVIFPGGADAAVVRVRPVNGKPDASTIGVAACTDCNPRYV
CCCCCCHHHHHHHHHHHCCCEEEEECCCCEEEEEEEECCCCCCCCCEEEEEECCCCCCEE
YLNPLEGAKAAVAEAARNLSCVGAEPLAITNNLNFGSPEKPVGYWQLANACKGIAEACRE
EECCCCCHHHHHHHHHHCCEECCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LDTPVTGGNVSLYNETLDSDGKPTPIYPTPVIGMVGRVEHINQVCGLAFQNAGDKVYLLG
HCCCCCCCCEEEEEHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
TQATTTLGGSEYLNTIHNTVAGIPPQVDFELEKAVQKTVREAIAAGLLNSAHDLAEGGLA
CCCEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
VALAECCIGGKLGATVEITGTDRLDAILFGETCGKIIVSVAPDKQAQFEAHLTQSLADNW
HHHHHHHCCCCCCCEEEEECCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHCCE
QVIGSVSNTNQLQITVNNQAVIAVSVEDMTTNWSEAIARRLHP
EEEEECCCCCEEEEEECCCEEEEEEECCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]