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The map label for this gene is mrdA [H]

Identifier: 170078216

GI number: 170078216

Start: 1687524

End: 1689329

Strand: Direct

Name: mrdA [H]

Synonym: SYNPCC7002_A1608

Alternate gene names: 170078216

Gene position: 1687524-1689329 (Clockwise)

Preceding gene: 170078215

Following gene: 170078217

Centisome position: 56.1

GC content: 55.54

Gene sequence:

>1806_bases
ATGACCCTCATCTCTCCCCTTGCAAAAGCCTCACGCAAAGAATCGGGTCGCACCGTTGGCCGGGGTGTTCGTCCCTGGGG
AATTATGTTTGCCGTTAGCTTGGCACTCCTGGGCGGCATTGGTTCCCGCTTGGCTTTTTTGCAACTCGTTAAGGGAGATG
AACTGCGACAAACGGCCCGGAATAATAGCGTCCGCATTGCCCCCAAACCACCGATCCGGGGTAATATGTTTGACCGCCAT
GGCAAGGTGCTGGCCACCACAAAACTTGCCCATGCCGTCTATGTGTGGCCCGTAGCCCGCACGAGACCCGATTGGCCAAA
AACGAAACAATTGCTCTCCCAGTTGGTAGGCATCGCCCCCGCCGAAATTGAAAAGCGCCTAGAATCCCAAGATATCTACG
CCACTGAACCCTTGGCGATCGCCCGCAATTTGACCCTTGCCCAAGTCACCGCCATCGAAGAACATCACCAGACCCTCGCC
GGGGTAGAGGTGATCATCGAACCGGTGCGTTACTATCCCGAAGGAGATACGGCCTCCCATGTCCTCGGTTACACGAGAGA
ATTAACCCCCGAAGAATTTGAGACCCGCCAAGCAGAAGGCTATCGCCTCCAGGATTACATCGGTAAATTAGGTCTAGAAG
CGTCCCTAGAATCCCGTCTGCGTGGGGAATGGGGCGGCCAAGAAATTCAAGTGGACCGCGATGGCCGGTTTGTGAAAATC
CTGGGAGAAAAACCAGCCCAGGCCGGGGAAGACCTCCGTCTTACCCTAGACGCTGAACTTCAAAAGGTTGCCCAGAGGGT
TTTGGGACGACGCAAAGGGGCGATCGTCGCCCTCGATCCGCGCAATGGTGATGTCTTGGCGATGGCGAGTTACCCTAACT
TTGATCCGAATATTTTTTCTGATCGCATTTCCCCCGAAAAATGGGCCGCCGTCACTGCCCAGGGCGATCCCTTTATTAAC
CGTGCCATTCGTGGGTTTCCGCCAGCATCGACTTTTAAAGTTGTGACCGCCGCCGCCGGGATGGAATCCGGCAAATATCC
AGCCAACACAGTGTTGAGCACCAGTCCTTACCTCGCCGCTGCTGGGGTTCGTTTCTATGAGTGGAACCGGGCTGGTTTTG
GGGCCGCTGGCTACGTGAAAGCGATGGCCTGGAGTAGTAACACCTTTTTTGGCCAGGTGGGGCGGGGTGTTGGCGGTGAA
ACCCTGATTGATTGGTCGCGCCGCTTTGGCTTTGGTTCACCCACTGGCATTGAACTCAACGAAGAAACCAGCGGTCTAAT
TCCGGATGATGATTGGACCCAAGAGCGCCTCGAGCGCCCCTGGAATGTGGGAGACACTGTAAATATGTCCATCGGTCAAG
GCTTAACGTTGGCGACCCCCCTACAGGTGGCCCAGATGTTTGCGGTAACAGCGAATGGCGGCTATTTAGTGCAACCCCAC
CTCGTCCAAACCGATACTCCGGTGAAAACGTCCCTCAAAATGGCCCCCAGTACCCTAGAAACTATTCGTCAAGGCTTGCG
GGCCGTGGTCACTAACGGTACTGGTACAGTGCTCAATATTCCTGGGATTCCAACGGCAGCGGGAAAAAGTGGCACGGCTG
AAGCTCCCCCCCGGGAAAACCATGCTTGGTTCGGTGCCTTTGCTCCCTATGACGAGGCAGAGATCGTTGTCGTCGCCTTT
GCAGAACATTCTGGTGGTGGTGGTGGCTCTGTGGCTGGGCCGATGGTGCGCGATGTGATGGCGGCTTATTTTGAATTGAA
GGAAAAGGCCGAAAATCCTGAAGCCACAACCGCAACCCCAGAATAG

Upstream 100 bases:

>100_bases
TGATCAACCTGGGCTTAGTCCTACTCAGTTTTATCTTGACCTAAAAAGCCTAATGCGCACGCTAAAATTAGAATCAATTT
TCCTTTTTTCCTAGGCACCC

Downstream 100 bases:

>100_bases
GCAGCTTATCGCTTGGCTGCATTCAATAATCTCAGCAGAATATGGCACAATAGGCAGGTTTAAATTTCCACAATTGAGTT
AACAAAATCCCCTGTGAATA

Product: penicillin-binding protein 2

Products: NA

Alternate protein names: PBP-2 [H]

Number of amino acids: Translated: 601; Mature: 600

Protein sequence:

>601_residues
MTLISPLAKASRKESGRTVGRGVRPWGIMFAVSLALLGGIGSRLAFLQLVKGDELRQTARNNSVRIAPKPPIRGNMFDRH
GKVLATTKLAHAVYVWPVARTRPDWPKTKQLLSQLVGIAPAEIEKRLESQDIYATEPLAIARNLTLAQVTAIEEHHQTLA
GVEVIIEPVRYYPEGDTASHVLGYTRELTPEEFETRQAEGYRLQDYIGKLGLEASLESRLRGEWGGQEIQVDRDGRFVKI
LGEKPAQAGEDLRLTLDAELQKVAQRVLGRRKGAIVALDPRNGDVLAMASYPNFDPNIFSDRISPEKWAAVTAQGDPFIN
RAIRGFPPASTFKVVTAAAGMESGKYPANTVLSTSPYLAAAGVRFYEWNRAGFGAAGYVKAMAWSSNTFFGQVGRGVGGE
TLIDWSRRFGFGSPTGIELNEETSGLIPDDDWTQERLERPWNVGDTVNMSIGQGLTLATPLQVAQMFAVTANGGYLVQPH
LVQTDTPVKTSLKMAPSTLETIRQGLRAVVTNGTGTVLNIPGIPTAAGKSGTAEAPPRENHAWFGAFAPYDEAEIVVVAF
AEHSGGGGGSVAGPMVRDVMAAYFELKEKAENPEATTATPE

Sequences:

>Translated_601_residues
MTLISPLAKASRKESGRTVGRGVRPWGIMFAVSLALLGGIGSRLAFLQLVKGDELRQTARNNSVRIAPKPPIRGNMFDRH
GKVLATTKLAHAVYVWPVARTRPDWPKTKQLLSQLVGIAPAEIEKRLESQDIYATEPLAIARNLTLAQVTAIEEHHQTLA
GVEVIIEPVRYYPEGDTASHVLGYTRELTPEEFETRQAEGYRLQDYIGKLGLEASLESRLRGEWGGQEIQVDRDGRFVKI
LGEKPAQAGEDLRLTLDAELQKVAQRVLGRRKGAIVALDPRNGDVLAMASYPNFDPNIFSDRISPEKWAAVTAQGDPFIN
RAIRGFPPASTFKVVTAAAGMESGKYPANTVLSTSPYLAAAGVRFYEWNRAGFGAAGYVKAMAWSSNTFFGQVGRGVGGE
TLIDWSRRFGFGSPTGIELNEETSGLIPDDDWTQERLERPWNVGDTVNMSIGQGLTLATPLQVAQMFAVTANGGYLVQPH
LVQTDTPVKTSLKMAPSTLETIRQGLRAVVTNGTGTVLNIPGIPTAAGKSGTAEAPPRENHAWFGAFAPYDEAEIVVVAF
AEHSGGGGGSVAGPMVRDVMAAYFELKEKAENPEATTATPE
>Mature_600_residues
TLISPLAKASRKESGRTVGRGVRPWGIMFAVSLALLGGIGSRLAFLQLVKGDELRQTARNNSVRIAPKPPIRGNMFDRHG
KVLATTKLAHAVYVWPVARTRPDWPKTKQLLSQLVGIAPAEIEKRLESQDIYATEPLAIARNLTLAQVTAIEEHHQTLAG
VEVIIEPVRYYPEGDTASHVLGYTRELTPEEFETRQAEGYRLQDYIGKLGLEASLESRLRGEWGGQEIQVDRDGRFVKIL
GEKPAQAGEDLRLTLDAELQKVAQRVLGRRKGAIVALDPRNGDVLAMASYPNFDPNIFSDRISPEKWAAVTAQGDPFINR
AIRGFPPASTFKVVTAAAGMESGKYPANTVLSTSPYLAAAGVRFYEWNRAGFGAAGYVKAMAWSSNTFFGQVGRGVGGET
LIDWSRRFGFGSPTGIELNEETSGLIPDDDWTQERLERPWNVGDTVNMSIGQGLTLATPLQVAQMFAVTANGGYLVQPHL
VQTDTPVKTSLKMAPSTLETIRQGLRAVVTNGTGTVLNIPGIPTAAGKSGTAEAPPRENHAWFGAFAPYDEAEIVVVAFA
EHSGGGGGSVAGPMVRDVMAAYFELKEKAENPEATTATPE

Specific function: Cell wall formation; PBP-2 is responsible for the determination of the rod shape of the cell. Its synthesize cross- linked peptidoglycan from the lipid intermediates [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell inner membrane [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786854, Length=596, Percent_Identity=31.0402684563758, Blast_Score=277, Evalue=2e-75,
Organism=Escherichia coli, GI1786272, Length=602, Percent_Identity=24.9169435215947, Blast_Score=129, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR017790 [H]

Pfam domain/function: PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 65047; Mature: 64915

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLISPLAKASRKESGRTVGRGVRPWGIMFAVSLALLGGIGSRLAFLQLVKGDELRQTAR
CCCCHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHC
NNSVRIAPKPPIRGNMFDRHGKVLATTKLAHAVYVWPVARTRPDWPKTKQLLSQLVGIAP
CCCEEECCCCCCCCCCHHCCCCEEEEEHHEEEEEEEEECCCCCCCHHHHHHHHHHHCCCH
AEIEKRLESQDIYATEPLAIARNLTLAQVTAIEEHHQTLAGVEVIIEPVRYYPEGDTASH
HHHHHHHCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
VLGYTRELTPEEFETRQAEGYRLQDYIGKLGLEASLESRLRGEWGGQEIQVDRDGRFVKI
HHHHHHCCCHHHHHHHHCCCEEHHHHHHHHCCHHHHHHHHCCCCCCCEEEECCCCCEEEE
LGEKPAQAGEDLRLTLDAELQKVAQRVLGRRKGAIVALDPRNGDVLAMASYPNFDPNIFS
ECCCCCCCCCCEEEEECHHHHHHHHHHHCCCCCCEEEECCCCCCEEEEECCCCCCCCHHH
DRISPEKWAAVTAQGDPFINRAIRGFPPASTFKVVTAAAGMESGKYPANTVLSTSPYLAA
CCCCCCCEEEEEECCCHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCEECCCCCHHH
AGVRFYEWNRAGFGAAGYVKAMAWSSNTFFGQVGRGVGGETLIDWSRRFGFGSPTGIELN
CCEEEEEECCCCCCCHHHHEEEEECCCCCHHHHCCCCCCCHHHHHHHHCCCCCCCCEEEC
EETSGLIPDDDWTQERLERPWNVGDTVNMSIGQGLTLATPLQVAQMFAVTANGGYLVQPH
CCCCCCCCCCCHHHHHHCCCCCCCCEEEECCCCCCEEECHHHHHHEEEEECCCCEEECCE
LVQTDTPVKTSLKMAPSTLETIRQGLRAVVTNGTGTVLNIPGIPTAAGKSGTAEAPPREN
EEECCCCCHHHHHCCHHHHHHHHHHHHEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCC
HAWFGAFAPYDEAEIVVVAFAEHSGGGGGSVAGPMVRDVMAAYFELKEKAENPEATTATP
CCEEEECCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
E
C
>Mature Secondary Structure 
TLISPLAKASRKESGRTVGRGVRPWGIMFAVSLALLGGIGSRLAFLQLVKGDELRQTAR
CCCHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHC
NNSVRIAPKPPIRGNMFDRHGKVLATTKLAHAVYVWPVARTRPDWPKTKQLLSQLVGIAP
CCCEEECCCCCCCCCCHHCCCCEEEEEHHEEEEEEEEECCCCCCCHHHHHHHHHHHCCCH
AEIEKRLESQDIYATEPLAIARNLTLAQVTAIEEHHQTLAGVEVIIEPVRYYPEGDTASH
HHHHHHHCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
VLGYTRELTPEEFETRQAEGYRLQDYIGKLGLEASLESRLRGEWGGQEIQVDRDGRFVKI
HHHHHHCCCHHHHHHHHCCCEEHHHHHHHHCCHHHHHHHHCCCCCCCEEEECCCCCEEEE
LGEKPAQAGEDLRLTLDAELQKVAQRVLGRRKGAIVALDPRNGDVLAMASYPNFDPNIFS
ECCCCCCCCCCEEEEECHHHHHHHHHHHCCCCCCEEEECCCCCCEEEEECCCCCCCCHHH
DRISPEKWAAVTAQGDPFINRAIRGFPPASTFKVVTAAAGMESGKYPANTVLSTSPYLAA
CCCCCCCEEEEEECCCHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCEECCCCCHHH
AGVRFYEWNRAGFGAAGYVKAMAWSSNTFFGQVGRGVGGETLIDWSRRFGFGSPTGIELN
CCEEEEEECCCCCCCHHHHEEEEECCCCCHHHHCCCCCCCHHHHHHHHCCCCCCCCEEEC
EETSGLIPDDDWTQERLERPWNVGDTVNMSIGQGLTLATPLQVAQMFAVTANGGYLVQPH
CCCCCCCCCCCHHHHHHCCCCCCCCEEEECCCCCCEEECHHHHHHEEEEECCCCEEECCE
LVQTDTPVKTSLKMAPSTLETIRQGLRAVVTNGTGTVLNIPGIPTAAGKSGTAEAPPREN
EEECCCCCHHHHHCCHHHHHHHHHHHHEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCC
HAWFGAFAPYDEAEIVVVAFAEHSGGGGGSVAGPMVRDVMAAYFELKEKAENPEATTATP
CCEEEECCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
E
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]