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The map label for this gene is hemK [C]

Identifier: 170078207

GI number: 170078207

Start: 1677718

End: 1678593

Strand: Direct

Name: hemK [C]

Synonym: SYNPCC7002_A1599

Alternate gene names: 170078207

Gene position: 1677718-1678593 (Clockwise)

Preceding gene: 170078206

Following gene: 170078208

Centisome position: 55.77

GC content: 52.85

Gene sequence:

>876_bases
TTGAGTGAGATTATTGCGGCTCAGGATTTAGTACGGTGGCGACAGTGGGCCAAAACCCAGGCGATCGCCACCGATATTTC
TGTTGAGGAAGTGGATTGGTTTCTCCAGGGGCTGACCACTGTGGATCGGTTGAGTTTGTGGCTGGGGATTCGGGAAGCTG
TGCAGAGTCAGGTGTCTTTGGTTGAACTTTCACGACTCTGGGAACGGCGCTGCCAAGAGAAAATCCCGGTGCAATATCTC
GTCGGGAAAACGCCCTGGCGCAATTTTGAGCTAGTTGTTTCTCCTGCGGTCTTGATCCCTCGACCCGAAACGGAATATTT
AATTGATCTGGCCCAGGCGAGTCATCGTGATTTACACGCAGGTCATTGGATCGATCTAGGAACGGGCAGTGGGGCGATCG
CCTTGGGTTTGGCCGACAGTTTTCCCAACGGAAAGATTCATGCCGTTGATCAGAGTGCCGCCGCCCTTGAGGTCGCCCGA
AAAAATGCGATCGCCTACGGATCACAAGATCGAATTCAGTTTTACCATGGCAATTGGTGGGAACCGCTGCAACACCTACG
GGGACAGGTGACGGGTATGGTCTCGAATCCCCCCTATATTCCCGCTGCCCTGCTGCCGGATTTACAACCAGAGGTTTATC
GCCATGAACCCCATAGCGCCCTTGATGGGGGCATGGATGGGTTAGCGGACCTACGAATTTTGGTAAATGAAGCGCCGGAC
TATCTTATTTCTGGTGGCATTTGGCTCGTTGAACTGATGCGTGGCCAGGGGGAAACGGTGGCGCAATTACTCGCAGACAA
TGGTCATTACACTCAAATTCAGATCATTCATGACTTTGCTGGGGGCGATCGCTACGTATCTGCTCAGCGCAAGTAA

Upstream 100 bases:

>100_bases
GTCGATGACCCTAATTCCCTCGACGGAATCGGCCCAGTTGATCCAAGCTGTCATTGAGCAGCAACGGCAACAACAATAGG
GTATTGGGAACGGTTGATTC

Downstream 100 bases:

>100_bases
ATATTAGTTTCATCGTGATCAGAGTCACGATAGCTTGCTTTAGGAAAACTTAATTTTAATTTGGGCTAGATATTTACTCT
AGGACGGGAATACTCATTTT

Product: methyltransferase, methylase of peptide chain release factors

Products: NA

Alternate protein names: M.Ssp6803HemKP [H]

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MSEIIAAQDLVRWRQWAKTQAIATDISVEEVDWFLQGLTTVDRLSLWLGIREAVQSQVSLVELSRLWERRCQEKIPVQYL
VGKTPWRNFELVVSPAVLIPRPETEYLIDLAQASHRDLHAGHWIDLGTGSGAIALGLADSFPNGKIHAVDQSAAALEVAR
KNAIAYGSQDRIQFYHGNWWEPLQHLRGQVTGMVSNPPYIPAALLPDLQPEVYRHEPHSALDGGMDGLADLRILVNEAPD
YLISGGIWLVELMRGQGETVAQLLADNGHYTQIQIIHDFAGGDRYVSAQRK

Sequences:

>Translated_291_residues
MSEIIAAQDLVRWRQWAKTQAIATDISVEEVDWFLQGLTTVDRLSLWLGIREAVQSQVSLVELSRLWERRCQEKIPVQYL
VGKTPWRNFELVVSPAVLIPRPETEYLIDLAQASHRDLHAGHWIDLGTGSGAIALGLADSFPNGKIHAVDQSAAALEVAR
KNAIAYGSQDRIQFYHGNWWEPLQHLRGQVTGMVSNPPYIPAALLPDLQPEVYRHEPHSALDGGMDGLADLRILVNEAPD
YLISGGIWLVELMRGQGETVAQLLADNGHYTQIQIIHDFAGGDRYVSAQRK
>Mature_290_residues
SEIIAAQDLVRWRQWAKTQAIATDISVEEVDWFLQGLTTVDRLSLWLGIREAVQSQVSLVELSRLWERRCQEKIPVQYLV
GKTPWRNFELVVSPAVLIPRPETEYLIDLAQASHRDLHAGHWIDLGTGSGAIALGLADSFPNGKIHAVDQSAAALEVARK
NAIAYGSQDRIQFYHGNWWEPLQHLRGQVTGMVSNPPYIPAALLPDLQPEVYRHEPHSALDGGMDGLADLRILVNEAPDY
LISGGIWLVELMRGQGETVAQLLADNGHYTQIQIIHDFAGGDRYVSAQRK

Specific function: Probable protein methyltransferase. May methylate a Gln residue in target proteins [H]

COG id: COG2890

COG function: function code J; Methylase of polypeptide chain release factors

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hemK family [H]

Homologues:

Organism=Homo sapiens, GI7705409, Length=265, Percent_Identity=32.4528301886792, Blast_Score=97, Evalue=1e-20,
Organism=Escherichia coli, GI1787463, Length=273, Percent_Identity=33.3333333333333, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI87082085, Length=277, Percent_Identity=31.0469314079422, Blast_Score=106, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24582226, Length=196, Percent_Identity=33.6734693877551, Blast_Score=107, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR004556
- InterPro:   IPR019874
- InterPro:   IPR007848 [H]

Pfam domain/function: PF05175 MTS [H]

EC number: 2.1.1.-

Molecular weight: Translated: 32509; Mature: 32378

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEIIAAQDLVRWRQWAKTQAIATDISVEEVDWFLQGLTTVDRLSLWLGIREAVQSQVSL
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VELSRLWERRCQEKIPVQYLVGKTPWRNFELVVSPAVLIPRPETEYLIDLAQASHRDLHA
HHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECEEEECCCCHHHHHHHHHHCCCCCCC
GHWIDLGTGSGAIALGLADSFPNGKIHAVDQSAAALEVARKNAIAYGSQDRIQFYHGNWW
CCEEEECCCCCEEEEEECCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCEEEECCCHH
EPLQHLRGQVTGMVSNPPYIPAALLPDLQPEVYRHEPHSALDGGMDGLADLRILVNEAPD
HHHHHHHHHEEEEECCCCCCCHHHCCCCCCHHHCCCCCHHHCCCCCCHHHHHHHHHCCCC
YLISGGIWLVELMRGQGETVAQLLADNGHYTQIQIIHDFAGGDRYVSAQRK
EEEECCHHHHHHHHCCCHHHHHHHHCCCCEEEEEEEEECCCCCEEECCCCC
>Mature Secondary Structure 
SEIIAAQDLVRWRQWAKTQAIATDISVEEVDWFLQGLTTVDRLSLWLGIREAVQSQVSL
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VELSRLWERRCQEKIPVQYLVGKTPWRNFELVVSPAVLIPRPETEYLIDLAQASHRDLHA
HHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECEEEECCCCHHHHHHHHHHCCCCCCC
GHWIDLGTGSGAIALGLADSFPNGKIHAVDQSAAALEVARKNAIAYGSQDRIQFYHGNWW
CCEEEECCCCCEEEEEECCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCEEEECCCHH
EPLQHLRGQVTGMVSNPPYIPAALLPDLQPEVYRHEPHSALDGGMDGLADLRILVNEAPD
HHHHHHHHHEEEEECCCCCCCHHHCCCCCCHHHCCCCCHHHCCCCCCHHHHHHHHHCCCC
YLISGGIWLVELMRGQGETVAQLLADNGHYTQIQIIHDFAGGDRYVSAQRK
EEEECCHHHHHHHHCCCHHHHHHHHCCCCEEEEEEEEECCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]