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The map label for this gene is cysH

Identifier: 170078106

GI number: 170078106

Start: 1579516

End: 1580265

Strand: Direct

Name: cysH

Synonym: SYNPCC7002_A1497

Alternate gene names: 170078106

Gene position: 1579516-1580265 (Clockwise)

Preceding gene: 170078105

Following gene: 170078111

Centisome position: 52.51

GC content: 52.0

Gene sequence:

>750_bases
ATGGGTGGGATGATGCCAGATCTTGATTTAGCGACCGTTAACGAAAAACTCAGCGAAGCCAATGCCGTTGAAGTTGTCCA
GTGGGCGTCCCAGACCTTTCCTGAAGGGCTGATCATGAGTACCAGTTTCGGGATTCAGTCGGCGGTAATGCTCCACCTCG
TCACCCAGGTCATCCCGGATATTCCTGTCGTTTGGATTGACACCGGCTATCTCCCAGAAGCCACCTATCGCTTTGCTGAA
GAATTAGGCGATCGCCTCAATCTCAACCTTAAAGTCTATCAGTCCCCCCTCAGTCCCGCGCGCATGGAAGCCCTCTACGG
CAAACTGTGGGAACAGGACAACATCGAAGCCTTTAACCGCTACGATTACATCCGCAAAGTCGAACCCATGCAACGAGCCC
TCAAGGAGTTAAACGCTAAAGCCTGGCTTGCTGGACTCCGCAAAGGTCAAACCGACCACCGCAAGACCCTCGGTTACGTC
GCCAAACAAGGCAAGCAGTACAAAATTCACCCAATTTTGACCTGGACTTCTAAGGACGTTTATGAGTATCTAATGGCCCA
TGATCTTCCCTATCATCCCTATTTTGATAAAGGCTATGTCACCGTTGGGGATTGGCACTCTAGTCGGCCCTTGATGGCAG
GCGATGAAAGCGAACGGGATACCCGTTTCCGGGGCCTAAAACAAGAATGTGGCTTACACCTTCCCAGCACCTCCGAAGAA
GCCCAGAGTTTAGACTCCAGCGGCCTCTGA

Upstream 100 bases:

>100_bases
TACCCGTAAAAGTATGCCACAACTGCATCTTTCCCACCTCAACCCCCGCGCGCAAACCGCCAACCCCCAAGCACAATCAA
TGCCAATGGGAGATGTTCAA

Downstream 100 bases:

>100_bases
TCAAGTTGCGGTAGTCGAGTTTGCCAGTTTGCCATGGCAAGCCATAGACAACAGAGCAATTGTTCATCCCAGAGACTAAA
AAAAGGCGAATCAATGATGA

Product: phosphoadenosine phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MGGMMPDLDLATVNEKLSEANAVEVVQWASQTFPEGLIMSTSFGIQSAVMLHLVTQVIPDIPVVWIDTGYLPEATYRFAE
ELGDRLNLNLKVYQSPLSPARMEALYGKLWEQDNIEAFNRYDYIRKVEPMQRALKELNAKAWLAGLRKGQTDHRKTLGYV
AKQGKQYKIHPILTWTSKDVYEYLMAHDLPYHPYFDKGYVTVGDWHSSRPLMAGDESERDTRFRGLKQECGLHLPSTSEE
AQSLDSSGL

Sequences:

>Translated_249_residues
MGGMMPDLDLATVNEKLSEANAVEVVQWASQTFPEGLIMSTSFGIQSAVMLHLVTQVIPDIPVVWIDTGYLPEATYRFAE
ELGDRLNLNLKVYQSPLSPARMEALYGKLWEQDNIEAFNRYDYIRKVEPMQRALKELNAKAWLAGLRKGQTDHRKTLGYV
AKQGKQYKIHPILTWTSKDVYEYLMAHDLPYHPYFDKGYVTVGDWHSSRPLMAGDESERDTRFRGLKQECGLHLPSTSEE
AQSLDSSGL
>Mature_248_residues
GGMMPDLDLATVNEKLSEANAVEVVQWASQTFPEGLIMSTSFGIQSAVMLHLVTQVIPDIPVVWIDTGYLPEATYRFAEE
LGDRLNLNLKVYQSPLSPARMEALYGKLWEQDNIEAFNRYDYIRKVEPMQRALKELNAKAWLAGLRKGQTDHRKTLGYVA
KQGKQYKIHPILTWTSKDVYEYLMAHDLPYHPYFDKGYVTVGDWHSSRPLMAGDESERDTRFRGLKQECGLHLPSTSEEA
QSLDSSGL

Specific function: Reduction of activated sulfate into sulfite

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily

Homologues:

Organism=Escherichia coli, GI1789121, Length=226, Percent_Identity=51.7699115044248, Blast_Score=230, Evalue=7e-62,
Organism=Saccharomyces cerevisiae, GI6325425, Length=228, Percent_Identity=33.3333333333333, Blast_Score=113, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CYSH_SYNP2 (B1XN08)

Other databases:

- EMBL:   CP000951
- RefSeq:   YP_001734744.1
- ProteinModelPortal:   B1XN08
- SMR:   B1XN08
- GeneID:   6055169
- GenomeReviews:   CP000951_GR
- KEGG:   syp:SYNPCC7002_A1497
- HOGENOM:   HBG758022
- OMA:   AGDESER
- ProtClustDB:   PRK02090
- GO:   GO:0005737
- HAMAP:   MF_00063
- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR011800
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- TIGRFAMs:   TIGR00434
- TIGRFAMs:   TIGR02057

Pfam domain/function: PF01507 PAPS_reduct

EC number: =1.8.4.8

Molecular weight: Translated: 28333; Mature: 28201

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGMMPDLDLATVNEKLSEANAVEVVQWASQTFPEGLIMSTSFGIQSAVMLHLVTQVIPD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHCC
IPVVWIDTGYLPEATYRFAEELGDRLNLNLKVYQSPLSPARMEALYGKLWEQDNIEAFNR
CCEEEEECCCCCHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHH
YDYIRKVEPMQRALKELNAKAWLAGLRKGQTDHRKTLGYVAKQGKQYKIHPILTWTSKDV
HHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEEEECHHHH
YEYLMAHDLPYHPYFDKGYVTVGDWHSSRPLMAGDESERDTRFRGLKQECGLHLPSTSEE
HHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHCHHHHCCCCCCCCCHH
AQSLDSSGL
HHHHCCCCC
>Mature Secondary Structure 
GGMMPDLDLATVNEKLSEANAVEVVQWASQTFPEGLIMSTSFGIQSAVMLHLVTQVIPD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHCC
IPVVWIDTGYLPEATYRFAEELGDRLNLNLKVYQSPLSPARMEALYGKLWEQDNIEAFNR
CCEEEEECCCCCHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHH
YDYIRKVEPMQRALKELNAKAWLAGLRKGQTDHRKTLGYVAKQGKQYKIHPILTWTSKDV
HHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEEEECHHHH
YEYLMAHDLPYHPYFDKGYVTVGDWHSSRPLMAGDESERDTRFRGLKQECGLHLPSTSEE
HHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHCHHHHCCCCCCCCCHH
AQSLDSSGL
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA