BacMap

Definition	Synechococcus sp. PCC 7002 chromosome, complete genome.
Accession	NC_010475
Length	3,008,047

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The map label for this gene is yhdN [H]

Identifier: 170078083

GI number: 170078083

Start: 1550954

End: 1551916

Strand: Reverse

Name: yhdN [H]

Synonym: SYNPCC7002_A1474

Alternate gene names: 170078083

Gene position: 1551916-1550954 (Counterclockwise)

Preceding gene: 170078087

Following gene: 170078082

Centisome position: 51.59

GC content: 53.69

Gene sequence:

>963_bases
ATGAAAACAAGACAACTAGGCCAAAGTGCCGTCCAAATCACCCCGATTATTCTCGGTACTTGGCAAGCGGGCAAGCGCAA
TTGGGCGGATATTGACGACCAAGAAATTGTGGCCGGGATCCGTGCCGCCGTAGATGCAGGCATTACGACCATCGATACCG
CTGAAATTTATGGCGATGGGGATTCTGAACGTCGGGTCGCCGAGGCGATCGCCCCCCAACGGGATCAAGTGACCCTATTA
ACGAAAGTCTTTGCCAATCACCTCCACCACGACCAGGTGATCACCGCCTGCGAAAATTCCCTCAACAGACTCCAGACAGA
CTACATCGATCTGTACCAAATCCACTGGCCAGCGGGAACGTGGAATTCTGACCTGGTGCCCATCGCTGAAACCATGGCCG
CTCTGAATCAATTGAAAGAACAGGGCAAAATTCGCGCTATTGGTGTGTCTAATTTTTCCTTGGCGCAACTCCAGGAAGCG
ATGGAACACGGCCAAATCGATAGCATTCAACCGCCCTATTCTTTATTTTGGCGGGCCATTGAACGGGAAATTCAACCTTT
CTGTGCGGCCCAGCAGATTTCGATCCTCGCCTATTCTTCCTTGGCCCAGGGTCTACTGACGGGGAAATTTGGCCCCGATC
ACCAGTTTGCGGCGGGGGATCACCGCTCCCACAACCGTCTTTATGCTGACCCGGAAAATTACCAACGGGTACAAACGGCC
CTCGGACTCCTGAAACCGATCGCCACGACAAAGAATTGCACCTTGGCTCAACTGGCGATCGCCTGGCTGATTCGGCAGCC
CCAAACCAATGCCATCGTCGGCGCGCGCAATGCTCAACAGGCGATCGCCAATGCCCAGGCCATCGATGTCGAGTTAACGG
CTAAAGATCTCGAAGCCATTGACCATATCGGGCGGACAGTAACCGATCCTCTAGACGAAAATCCGCTCCTATGGAACTGG
TAA

Upstream 100 bases:

>100_bases
CAACCCTTGCTCCCCCAGCTTATCGAATCTGACGGAGTAGATTAATTCCCCAGCGGAACAAGCTACAGTGGAACCAATGA
CCCGCCAGAAAAACGAGCTT

Downstream 100 bases:

>100_bases
GCACCAGGAAATTCAAATTCCTTTGGCTATACTGAAGGCAAGTTTCAGCGCTCTGCATCAACCCAATGAAAGCTTTAATT
TTGGCCCTGGGGATTTCCTG

Product: aldo/keto reductase

Products: NA

Alternate protein names: GSP69; AKR11B [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MKTRQLGQSAVQITPIILGTWQAGKRNWADIDDQEIVAGIRAAVDAGITTIDTAEIYGDGDSERRVAEAIAPQRDQVTLL
TKVFANHLHHDQVITACENSLNRLQTDYIDLYQIHWPAGTWNSDLVPIAETMAALNQLKEQGKIRAIGVSNFSLAQLQEA
MEHGQIDSIQPPYSLFWRAIEREIQPFCAAQQISILAYSSLAQGLLTGKFGPDHQFAAGDHRSHNRLYADPENYQRVQTA
LGLLKPIATTKNCTLAQLAIAWLIRQPQTNAIVGARNAQQAIANAQAIDVELTAKDLEAIDHIGRTVTDPLDENPLLWNW

Sequences:

>Translated_320_residues
MKTRQLGQSAVQITPIILGTWQAGKRNWADIDDQEIVAGIRAAVDAGITTIDTAEIYGDGDSERRVAEAIAPQRDQVTLL
TKVFANHLHHDQVITACENSLNRLQTDYIDLYQIHWPAGTWNSDLVPIAETMAALNQLKEQGKIRAIGVSNFSLAQLQEA
MEHGQIDSIQPPYSLFWRAIEREIQPFCAAQQISILAYSSLAQGLLTGKFGPDHQFAAGDHRSHNRLYADPENYQRVQTA
LGLLKPIATTKNCTLAQLAIAWLIRQPQTNAIVGARNAQQAIANAQAIDVELTAKDLEAIDHIGRTVTDPLDENPLLWNW
>Mature_320_residues
MKTRQLGQSAVQITPIILGTWQAGKRNWADIDDQEIVAGIRAAVDAGITTIDTAEIYGDGDSERRVAEAIAPQRDQVTLL
TKVFANHLHHDQVITACENSLNRLQTDYIDLYQIHWPAGTWNSDLVPIAETMAALNQLKEQGKIRAIGVSNFSLAQLQEA
MEHGQIDSIQPPYSLFWRAIEREIQPFCAAQQISILAYSSLAQGLLTGKFGPDHQFAAGDHRSHNRLYADPENYQRVQTA
LGLLKPIATTKNCTLAQLAIAWLIRQPQTNAIVGARNAQQAIANAQAIDVELTAKDLEAIDHIGRTVTDPLDENPLLWNW

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=328, Percent_Identity=27.1341463414634, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI27436969, Length=328, Percent_Identity=28.3536585365854, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI27436962, Length=328, Percent_Identity=26.8292682926829, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI4504825, Length=325, Percent_Identity=28.3076923076923, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI27436966, Length=328, Percent_Identity=26.8292682926829, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI27436971, Length=327, Percent_Identity=26.2996941896024, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI223468663, Length=328, Percent_Identity=26.219512195122, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI223718702, Length=206, Percent_Identity=32.5242718446602, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI5453543, Length=309, Percent_Identity=25.8899676375405, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI45446745, Length=327, Percent_Identity=25.0764525993884, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI4503285, Length=327, Percent_Identity=25.0764525993884, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI310109920, Length=327, Percent_Identity=25.0764525993884, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI41152114, Length=206, Percent_Identity=31.0679611650485, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI310109922, Length=313, Percent_Identity=24.9201277955272, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI24497583, Length=295, Percent_Identity=26.1016949152542, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI24497585, Length=309, Percent_Identity=24.5954692556634, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI291291012, Length=303, Percent_Identity=23.7623762376238, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI41327764, Length=207, Percent_Identity=31.8840579710145, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI24497577, Length=317, Percent_Identity=23.0283911671924, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI5174391, Length=317, Percent_Identity=23.0283911671924, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4502049, Length=331, Percent_Identity=25.3776435045317, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI223718708, Length=149, Percent_Identity=32.2147651006711, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI5174695, Length=320, Percent_Identity=24.375, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1788070, Length=318, Percent_Identity=34.2767295597484, Blast_Score=158, Evalue=5e-40,
Organism=Escherichia coli, GI1788081, Length=308, Percent_Identity=34.4155844155844, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI87081735, Length=322, Percent_Identity=30.1242236024845, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI1789199, Length=352, Percent_Identity=29.5454545454545, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1789375, Length=329, Percent_Identity=27.355623100304, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786400, Length=180, Percent_Identity=32.7777777777778, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI87082198, Length=187, Percent_Identity=27.807486631016, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI48994888, Length=304, Percent_Identity=25.6578947368421, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17564128, Length=312, Percent_Identity=26.2820512820513, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17537075, Length=325, Percent_Identity=27.3846153846154, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17562292, Length=183, Percent_Identity=31.1475409836066, Blast_Score=81, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17561298, Length=317, Percent_Identity=25.5520504731861, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17566692, Length=206, Percent_Identity=30.5825242718447, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17550248, Length=203, Percent_Identity=26.1083743842365, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17561300, Length=206, Percent_Identity=31.0679611650485, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17537077, Length=319, Percent_Identity=26.6457680250784, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17552492, Length=198, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17537079, Length=339, Percent_Identity=24.188790560472, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI212645785, Length=329, Percent_Identity=25.2279635258359, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=346, Percent_Identity=29.4797687861272, Blast_Score=127, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6323998, Length=334, Percent_Identity=24.251497005988, Blast_Score=79, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6324694, Length=225, Percent_Identity=28, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6319958, Length=291, Percent_Identity=25.4295532646048, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320079, Length=312, Percent_Identity=23.7179487179487, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320576, Length=204, Percent_Identity=25.9803921568627, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24644950, Length=331, Percent_Identity=28.3987915407855, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24646155, Length=328, Percent_Identity=27.1341463414634, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24663317, Length=324, Percent_Identity=26.8518518518519, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24662789, Length=335, Percent_Identity=24.7761194029851, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24662781, Length=210, Percent_Identity=30.4761904761905, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24657054, Length=290, Percent_Identity=25.8620689655172, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI45553081, Length=209, Percent_Identity=29.1866028708134, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24646159, Length=225, Percent_Identity=28, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24662785, Length=209, Percent_Identity=29.6650717703349, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281366140, Length=176, Percent_Identity=30.1136363636364, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI20129731, Length=206, Percent_Identity=26.6990291262136, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21356425, Length=182, Percent_Identity=24.7252747252747, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR018170
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35425; Mature: 35425

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00062 ALDOKETO_REDUCTASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTRQLGQSAVQITPIILGTWQAGKRNWADIDDQEIVAGIRAAVDAGITTIDTAEIYGDG
CCCHHHCCHHEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEECHHEECCC
DSERRVAEAIAPQRDQVTLLTKVFANHLHHDQVITACENSLNRLQTDYIDLYQIHWPAGT
CHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCC
WNSDLVPIAETMAALNQLKEQGKIRAIGVSNFSLAQLQEAMEHGQIDSIQPPYSLFWRAI
CCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHH
EREIQPFCAAQQISILAYSSLAQGLLTGKFGPDHQFAAGDHRSHNRLYADPENYQRVQTA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
LGLLKPIATTKNCTLAQLAIAWLIRQPQTNAIVGARNAQQAIANAQAIDVELTAKDLEAI
HHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEECCHHHHHHHCCCEEEEEECHHHHHHH
DHIGRTVTDPLDENPLLWNW
HHHCHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MKTRQLGQSAVQITPIILGTWQAGKRNWADIDDQEIVAGIRAAVDAGITTIDTAEIYGDG
CCCHHHCCHHEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEECHHEECCC
DSERRVAEAIAPQRDQVTLLTKVFANHLHHDQVITACENSLNRLQTDYIDLYQIHWPAGT
CHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCC
WNSDLVPIAETMAALNQLKEQGKIRAIGVSNFSLAQLQEAMEHGQIDSIQPPYSLFWRAI
CCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHH
EREIQPFCAAQQISILAYSSLAQGLLTGKFGPDHQFAAGDHRSHNRLYADPENYQRVQTA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
LGLLKPIATTKNCTLAQLAIAWLIRQPQTNAIVGARNAQQAIANAQAIDVELTAKDLEAI
HHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEECCHHHHHHHCCCEEEEEECHHHHHHH
DHIGRTVTDPLDENPLLWNW
HHHCHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 9298659 [H]