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The map label for this gene is murQ

Identifier: 170078031

GI number: 170078031

Start: 1494459

End: 1495364

Strand: Direct

Name: murQ

Synonym: SYNPCC7002_A1422

Alternate gene names: 170078031

Gene position: 1494459-1495364 (Clockwise)

Preceding gene: 170078030

Following gene: 170078033

Centisome position: 49.68

GC content: 50.77

Gene sequence:

>906_bases
TTGAATTCCTACGAAAGTCGCGGCCATTTACTTACAGAACAGGTCAACCCCCAGAGTCAAAATTTAGATCAAATGTCGGC
TTTGGAATTGGTCGATCTCTTTAACCAAGAGGATCAAAAAACCCTGGAGGCGATCGCCAATGCCCGCGAAGCACTAGCCC
AGGCCATCGAAATCACCAGTGAAGCTCTGATGCATGGTGGGCGGTTATTTTATGTGGGGGCTGGAACCAGTGGCCGCCTC
GGCGTTTTAGACGCTGCGGAATGTCCGCCCACCTTTTGCACCCCCCCGGAACTGGTTCAAGGGATTATTGCCGGAGGGGC
CGGAGCTCTCGTGCGCAGTTCAGAAGATCTTGAAGACCGGGCCGAAGACGGAAAAAAGGCGATCGCCCAACGACAGATCA
CCGAATTAGATGTCGTTGTCGGTATTACTGCGGGGGGAACCACTCCCTATGTCCAAGGTGCCCTGATTGCCGCCCAACAG
CGCGGAGCGAAAACTATTTTCATTAGTTGCGTTCCGGCCGAACAAGTGCCCTTTGCTGCCGCTGTTGATATTCGTCTACT
GACTGGCCCCGAAATTCTGGCAGGCTCGACCCGTCTTAAGGCCGGAACTGTCACCAAAATGGCCTTAAATATTCTTTCGA
CTAGCGTCATGGTTAAGCTCGGTAAAGTTTACGGTAATCGCATGATTGATGTTGCCGTCACAAACCATAAACTCCATGAC
CGGGCACTGCGCATCCTCCAAGACCTAACAGATTTAAGCCGTGAGGAAGCGGCCATCCTTCTAGAAAAATCCCAGCGTCG
CGTCAAAATAGCATTATTAATGCATTGGAAAAATGTAGACGCCTCAGAAGCAGAGCATTTATTAAAAGTCCATCAAGGCA
GTCTCCGAACAGCGTTAAAGTCATAA

Upstream 100 bases:

>100_bases
GACATAAGAGCAAATGGACGAAAGTTCAGGTGGTTGATTTCTTCGGACAGTAGATGGTTAACTTTGTTTATTTATCATGC
GTTAGTGCGAGGGCAATTCC

Downstream 100 bases:

>100_bases
ACTTATTTTATAAGCGCTTATCTAACATGTCTGCCAGTAAAGAAAAAACCGCAAGTTGAGTTGCTGCAACAAAGAGAATC
AAAGTAGATTCTGTCAAGTC

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MNSYESRGHLLTEQVNPQSQNLDQMSALELVDLFNQEDQKTLEAIANAREALAQAIEITSEALMHGGRLFYVGAGTSGRL
GVLDAAECPPTFCTPPELVQGIIAGGAGALVRSSEDLEDRAEDGKKAIAQRQITELDVVVGITAGGTTPYVQGALIAAQQ
RGAKTIFISCVPAEQVPFAAAVDIRLLTGPEILAGSTRLKAGTVTKMALNILSTSVMVKLGKVYGNRMIDVAVTNHKLHD
RALRILQDLTDLSREEAAILLEKSQRRVKIALLMHWKNVDASEAEHLLKVHQGSLRTALKS

Sequences:

>Translated_301_residues
MNSYESRGHLLTEQVNPQSQNLDQMSALELVDLFNQEDQKTLEAIANAREALAQAIEITSEALMHGGRLFYVGAGTSGRL
GVLDAAECPPTFCTPPELVQGIIAGGAGALVRSSEDLEDRAEDGKKAIAQRQITELDVVVGITAGGTTPYVQGALIAAQQ
RGAKTIFISCVPAEQVPFAAAVDIRLLTGPEILAGSTRLKAGTVTKMALNILSTSVMVKLGKVYGNRMIDVAVTNHKLHD
RALRILQDLTDLSREEAAILLEKSQRRVKIALLMHWKNVDASEAEHLLKVHQGSLRTALKS
>Mature_301_residues
MNSYESRGHLLTEQVNPQSQNLDQMSALELVDLFNQEDQKTLEAIANAREALAQAIEITSEALMHGGRLFYVGAGTSGRL
GVLDAAECPPTFCTPPELVQGIIAGGAGALVRSSEDLEDRAEDGKKAIAQRQITELDVVVGITAGGTTPYVQGALIAAQQ
RGAKTIFISCVPAEQVPFAAAVDIRLLTGPEILAGSTRLKAGTVTKMALNILSTSVMVKLGKVYGNRMIDVAVTNHKLHD
RALRILQDLTDLSREEAAILLEKSQRRVKIALLMHWKNVDASEAEHLLKVHQGSLRTALKS

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain

Homologues:

Organism=Escherichia coli, GI1788768, Length=290, Percent_Identity=44.1379310344828, Blast_Score=239, Evalue=2e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURQ_SYNP2 (B1XMC7)

Other databases:

- EMBL:   CP000951
- RefSeq:   YP_001734669.1
- ProteinModelPortal:   B1XMC7
- SMR:   B1XMC7
- GeneID:   6055044
- GenomeReviews:   CP000951_GR
- KEGG:   syp:SYNPCC7002_A1422
- HOGENOM:   HBG703490
- OMA:   HLLTEQI
- ProtClustDB:   PRK05441
- HAMAP:   MF_00068
- InterPro:   IPR005486
- InterPro:   IPR005488
- TIGRFAMs:   TIGR00274

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 32381; Mature: 32381

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS01272 GCKR; PS51464 SIS

Important sites: ACT_SITE 87-87 ACT_SITE 118-118

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSYESRGHLLTEQVNPQSQNLDQMSALELVDLFNQEDQKTLEAIANAREALAQAIEITS
CCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
EALMHGGRLFYVGAGTSGRLGVLDAAECPPTFCTPPELVQGIIAGGAGALVRSSEDLEDR
HHHHCCCEEEEEECCCCCCEEECCCCCCCCCCCCCHHHHHHHHCCCCCHHHCCCCCHHHH
AEDGKKAIAQRQITELDVVVGITAGGTTPYVQGALIAAQQRGAKTIFISCVPAEQVPFAA
HHHHHHHHHHHHHHEEEEEEEEECCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCEE
AVDIRLLTGPEILAGSTRLKAGTVTKMALNILSTSVMVKLGKVYGNRMIDVAVTNHKLHD
EEEEEEECCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCHHHH
RALRILQDLTDLSREEAAILLEKSQRRVKIALLMHWKNVDASEAEHLLKVHQGSLRTALK
HHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEEEEEECCCCHHHHHHHHHHHCCHHHHHHC
S
C
>Mature Secondary Structure
MNSYESRGHLLTEQVNPQSQNLDQMSALELVDLFNQEDQKTLEAIANAREALAQAIEITS
CCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
EALMHGGRLFYVGAGTSGRLGVLDAAECPPTFCTPPELVQGIIAGGAGALVRSSEDLEDR
HHHHCCCEEEEEECCCCCCEEECCCCCCCCCCCCCHHHHHHHHCCCCCHHHCCCCCHHHH
AEDGKKAIAQRQITELDVVVGITAGGTTPYVQGALIAAQQRGAKTIFISCVPAEQVPFAA
HHHHHHHHHHHHHHEEEEEEEEECCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCEE
AVDIRLLTGPEILAGSTRLKAGTVTKMALNILSTSVMVKLGKVYGNRMIDVAVTNHKLHD
EEEEEEECCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCHHHH
RALRILQDLTDLSREEAAILLEKSQRRVKIALLMHWKNVDASEAEHLLKVHQGSLRTALK
HHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEEEEEECCCCHHHHHHHHHHHCCHHHHHHC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA