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The map label for this gene is pyrG

Identifier: 170078029

GI number: 170078029

Start: 1492392

End: 1494050

Strand: Direct

Name: pyrG

Synonym: SYNPCC7002_A1420

Alternate gene names: 170078029

Gene position: 1492392-1494050 (Clockwise)

Preceding gene: 170078028

Following gene: 170078030

Centisome position: 49.61

GC content: 50.87

Gene sequence:

>1659_bases
ATGGCTAAATTTATCTTTGTCACCGGTGGTGTGGTCTCCAGCATCGGGAAAGGCATTGTGGCAGCAAGTTTGGGGCGTTT
ACTCAAGTCCCGTGACTATTCGGTGTCGATCCTGAAGCTCGATCCCTACATTAACGTCGATCCTGGCACCATGAGCCCGT
TCCAACATGGGGAAGTTTTTGTCACCGAGGATGGTGCAGAAACAGACCTCGACCTCGGCCACTACGAACGATTTACCGAT
ACCTCCATGTCTCGCCTTAATAGTGTGACCACCGGTTCCATTTATCAAGCGGTGATTAATAAGGAGCGACGGGGCGATTA
TCAAGGGGGGACGGTTCAAGTCATTCCCCACATTACCAACGAGATTAAAGAACGAATTTTTCGCGTGGCGGAGAATACGA
ATCCTGATTTTGTGATCACAGAAATTGGCGGTACCGTCGGCGATATTGAATCTTTACCGTTCCTAGAAGCGATTCGTCAG
TTCCGCAAAGAGGCTGGCCGGGACAATGTTTTGTATATGCACGTAACCTTGATCCCCTGGATTTCGTCGGCGGGGGAAAT
GAAAACGAAGCCCACCCAACATTCTGTAAAAGAATTGCGCTCTATTGGGATTCAGCCGGATGTGCTGGTGTGTCGTTGCG
ATCGCCCCCTACCCCAAGGCCAACGGGAAAAAATTTCGGAGTTCTGTAATGTCCCAGAAGAACAGGTGATCACCTCCCAG
GATGCCAGCAGCATTTACGAAGTACCCCTGATGCTGGAACGGGAAGGCTTGGCAGAACAAACCCTCAAGCTGCTGCGAAT
GGAACCCCGGCAACCAAATTTAGAGCAGTGGCAAAACCTCGTCGAACGGATGAAGCGCCCGAACCGCCATATGGATATCG
CCATTGTCGGCAAATATGTCCAGCTCAATGATGCCTATTTATCCGTGGTGGAATCCCTCGGCCATGCGGCGATCGCCAAT
GACATGGACATCAAACTCCATTGGGTCAACGCTGAGGATATCGAAAAACACGGCGCGTCCATGTATCTTGCGGATATGGC
GGGGATCGTCGTTCCCGGAGGATTTGGTTTACGGGGCGTTGATGGAAAAGTAGCGGCCATTGAATATGCCCGGCTCAATC
AAATCCCGTTCCTGGGCCTTTGTCTTGGGATGCAATCTTCAGTGATTGAATGGGCCCGTAACGTTGCCAAATTAGAGGAT
GCCCACAGCGCCGAATTCAACCCCGAAGCGAAAAACCCCGTGATTAATCTTTTGCCAGAACAGCGGGATGTGGTGGATCT
TGGTGGCACCATGCGCCTGGGTTTATATCCCTGTCGGCTCACCCCTGACACCCTGACCTATCAACTCTATGGCCAAGAGG
TGATCTACGAACGTCACCGTCACCGCTACGAATTTAACAATGCCTACCGGAGTTTGTTCTTAGAAACGGGCTATCAAGTG
AGTGGAACTTCCCCCGATGGTCGCTTGGTAGAAATTATTGAATATGCTGACCATCCGTTCTTTATTGCGACCCAGTTCCA
CCCCGAATTTCAATCTCGTCCGAACCATCCCCACCCCCTCTTTTTCGGGTTTATTCAAGCGGCGGGAAACCACAAGTCCC
AACCGATTTCTGATGAGCTAGATAACCAGAGTACGGAGATGTCTATTTCTCTGTCCTAG

Upstream 100 bases:

>100_bases
CATGGGTTCAGCCTTTGCCAGTAAATTTTCTCTGTCTATCGAAAGGAGTATGGCAAAATGAACAGGTTAAAAACATTGTG
AACGGAACGGGTATCGGTTA

Downstream 100 bases:

>100_bases
GGCGAAGAACCTGTAATGAATTAACTTGATCACAACGATAAAAACCATGGCAAATTCCGTACATCATATTGTTCTGTTTG
AATTGGCAGCAGCAACTGGG

Product: CTP synthetase

Products: NA

Alternate protein names: CTP synthetase; UTP--ammonia ligase

Number of amino acids: Translated: 552; Mature: 551

Protein sequence:

>552_residues
MAKFIFVTGGVVSSIGKGIVAASLGRLLKSRDYSVSILKLDPYINVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFTD
TSMSRLNSVTTGSIYQAVINKERRGDYQGGTVQVIPHITNEIKERIFRVAENTNPDFVITEIGGTVGDIESLPFLEAIRQ
FRKEAGRDNVLYMHVTLIPWISSAGEMKTKPTQHSVKELRSIGIQPDVLVCRCDRPLPQGQREKISEFCNVPEEQVITSQ
DASSIYEVPLMLEREGLAEQTLKLLRMEPRQPNLEQWQNLVERMKRPNRHMDIAIVGKYVQLNDAYLSVVESLGHAAIAN
DMDIKLHWVNAEDIEKHGASMYLADMAGIVVPGGFGLRGVDGKVAAIEYARLNQIPFLGLCLGMQSSVIEWARNVAKLED
AHSAEFNPEAKNPVINLLPEQRDVVDLGGTMRLGLYPCRLTPDTLTYQLYGQEVIYERHRHRYEFNNAYRSLFLETGYQV
SGTSPDGRLVEIIEYADHPFFIATQFHPEFQSRPNHPHPLFFGFIQAAGNHKSQPISDELDNQSTEMSISLS

Sequences:

>Translated_552_residues
MAKFIFVTGGVVSSIGKGIVAASLGRLLKSRDYSVSILKLDPYINVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFTD
TSMSRLNSVTTGSIYQAVINKERRGDYQGGTVQVIPHITNEIKERIFRVAENTNPDFVITEIGGTVGDIESLPFLEAIRQ
FRKEAGRDNVLYMHVTLIPWISSAGEMKTKPTQHSVKELRSIGIQPDVLVCRCDRPLPQGQREKISEFCNVPEEQVITSQ
DASSIYEVPLMLEREGLAEQTLKLLRMEPRQPNLEQWQNLVERMKRPNRHMDIAIVGKYVQLNDAYLSVVESLGHAAIAN
DMDIKLHWVNAEDIEKHGASMYLADMAGIVVPGGFGLRGVDGKVAAIEYARLNQIPFLGLCLGMQSSVIEWARNVAKLED
AHSAEFNPEAKNPVINLLPEQRDVVDLGGTMRLGLYPCRLTPDTLTYQLYGQEVIYERHRHRYEFNNAYRSLFLETGYQV
SGTSPDGRLVEIIEYADHPFFIATQFHPEFQSRPNHPHPLFFGFIQAAGNHKSQPISDELDNQSTEMSISLS
>Mature_551_residues
AKFIFVTGGVVSSIGKGIVAASLGRLLKSRDYSVSILKLDPYINVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFTDT
SMSRLNSVTTGSIYQAVINKERRGDYQGGTVQVIPHITNEIKERIFRVAENTNPDFVITEIGGTVGDIESLPFLEAIRQF
RKEAGRDNVLYMHVTLIPWISSAGEMKTKPTQHSVKELRSIGIQPDVLVCRCDRPLPQGQREKISEFCNVPEEQVITSQD
ASSIYEVPLMLEREGLAEQTLKLLRMEPRQPNLEQWQNLVERMKRPNRHMDIAIVGKYVQLNDAYLSVVESLGHAAIAND
MDIKLHWVNAEDIEKHGASMYLADMAGIVVPGGFGLRGVDGKVAAIEYARLNQIPFLGLCLGMQSSVIEWARNVAKLEDA
HSAEFNPEAKNPVINLLPEQRDVVDLGGTMRLGLYPCRLTPDTLTYQLYGQEVIYERHRHRYEFNNAYRSLFLETGYQVS
GTSPDGRLVEIIEYADHPFFIATQFHPEFQSRPNHPHPLFFGFIQAAGNHKSQPISDELDNQSTEMSISLS

Specific function: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen

COG id: COG0504

COG function: function code F; CTP synthase (UTP-ammonia lyase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain

Homologues:

Organism=Homo sapiens, GI148491070, Length=547, Percent_Identity=47.5319926873857, Blast_Score=523, Evalue=1e-148,
Organism=Homo sapiens, GI28559085, Length=547, Percent_Identity=47.3491773308958, Blast_Score=508, Evalue=1e-144,
Organism=Homo sapiens, GI28559083, Length=547, Percent_Identity=47.3491773308958, Blast_Score=508, Evalue=1e-144,
Organism=Homo sapiens, GI221316689, Length=547, Percent_Identity=47.3491773308958, Blast_Score=508, Evalue=1e-144,
Organism=Escherichia coli, GI1789142, Length=535, Percent_Identity=55.1401869158878, Blast_Score=595, Evalue=1e-171,
Organism=Caenorhabditis elegans, GI25148299, Length=602, Percent_Identity=40.6976744186046, Blast_Score=440, Evalue=1e-123,
Organism=Saccharomyces cerevisiae, GI6319432, Length=576, Percent_Identity=42.8819444444444, Blast_Score=463, Evalue=1e-131,
Organism=Saccharomyces cerevisiae, GI6322563, Length=563, Percent_Identity=43.3392539964476, Blast_Score=461, Evalue=1e-130,
Organism=Drosophila melanogaster, GI24664469, Length=558, Percent_Identity=47.1326164874552, Blast_Score=509, Evalue=1e-144,
Organism=Drosophila melanogaster, GI21357815, Length=503, Percent_Identity=45.9244532803181, Blast_Score=436, Evalue=1e-122,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): PYRG_SYNP2 (B1XMC5)

Other databases:

- EMBL:   CP000951
- RefSeq:   YP_001734667.1
- ProteinModelPortal:   B1XMC5
- SMR:   B1XMC5
- GeneID:   6055043
- GenomeReviews:   CP000951_GR
- KEGG:   syp:SYNPCC7002_A1420
- HOGENOM:   HBG597806
- OMA:   RVTMQKL
- ProtClustDB:   PRK05380
- HAMAP:   MF_01227
- InterPro:   IPR004468
- InterPro:   IPR017456
- InterPro:   IPR017926
- InterPro:   IPR000991
- TIGRFAMs:   TIGR00337

Pfam domain/function: PF06418 CTP_synth_N; PF00117 GATase

EC number: =6.3.4.2

Molecular weight: Translated: 61993; Mature: 61862

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS51273 GATASE_TYPE_1

Important sites: ACT_SITE 381-381 ACT_SITE 507-507 ACT_SITE 509-509

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKFIFVTGGVVSSIGKGIVAASLGRLLKSRDYSVSILKLDPYINVDPGTMSPFQHGEVF
CCEEEEEECHHHHHHCCHHHHHHHHHHHHCCCCEEEEEEECCEEECCCCCCCCCCCCEEE
VTEDGAETDLDLGHYERFTDTSMSRLNSVTTGSIYQAVINKERRGDYQGGTVQVIPHITN
EECCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCEEEEEHHHHH
EIKERIFRVAENTNPDFVITEIGGTVGDIESLPFLEAIRQFRKEAGRDNVLYMHVTLIPW
HHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEEHH
ISSAGEMKTKPTQHSVKELRSIGIQPDVLVCRCDRPLPQGQREKISEFCNVPEEQVITSQ
HCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCHHHHCCCC
DASSIYEVPLMLEREGLAEQTLKLLRMEPRQPNLEQWQNLVERMKRPNRHMDIAIVGKYV
CCHHHHHCCEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEEE
QLNDAYLSVVESLGHAAIANDMDIKLHWVNAEDIEKHGASMYLADMAGIVVPGGFGLRGV
EECHHHHHHHHHHCCHHCCCCCEEEEEEECHHHHHHCCCEEEEEHHCCEEECCCCCCCCC
DGKVAAIEYARLNQIPFLGLCLGMQSSVIEWARNVAKLEDAHSAEFNPEAKNPVINLLPE
CCCEEEEEHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCC
QRDVVDLGGTMRLGLYPCRLTPDTLTYQLYGQEVIYERHRHRYEFNNAYRSLFLETGYQV
CCCEEECCCEEEEEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
SGTSPDGRLVEIIEYADHPFFIATQFHPEFQSRPNHPHPLFFGFIQAAGNHKSQPISDEL
ECCCCCCCEEEEEECCCCCEEEEEEECCHHHCCCCCCCHHHHHHHHHCCCCCCCCCCHHH
DNQSTEMSISLS
CCCCCEEEEEEC
>Mature Secondary Structure 
AKFIFVTGGVVSSIGKGIVAASLGRLLKSRDYSVSILKLDPYINVDPGTMSPFQHGEVF
CEEEEEECHHHHHHCCHHHHHHHHHHHHCCCCEEEEEEECCEEECCCCCCCCCCCCEEE
VTEDGAETDLDLGHYERFTDTSMSRLNSVTTGSIYQAVINKERRGDYQGGTVQVIPHITN
EECCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCEEEEEHHHHH
EIKERIFRVAENTNPDFVITEIGGTVGDIESLPFLEAIRQFRKEAGRDNVLYMHVTLIPW
HHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEEHH
ISSAGEMKTKPTQHSVKELRSIGIQPDVLVCRCDRPLPQGQREKISEFCNVPEEQVITSQ
HCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCHHHHCCCC
DASSIYEVPLMLEREGLAEQTLKLLRMEPRQPNLEQWQNLVERMKRPNRHMDIAIVGKYV
CCHHHHHCCEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEEE
QLNDAYLSVVESLGHAAIANDMDIKLHWVNAEDIEKHGASMYLADMAGIVVPGGFGLRGV
EECHHHHHHHHHHCCHHCCCCCEEEEEEECHHHHHHCCCEEEEEHHCCEEECCCCCCCCC
DGKVAAIEYARLNQIPFLGLCLGMQSSVIEWARNVAKLEDAHSAEFNPEAKNPVINLLPE
CCCEEEEEHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCC
QRDVVDLGGTMRLGLYPCRLTPDTLTYQLYGQEVIYERHRHRYEFNNAYRSLFLETGYQV
CCCEEECCCEEEEEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
SGTSPDGRLVEIIEYADHPFFIATQFHPEFQSRPNHPHPLFFGFIQAAGNHKSQPISDEL
ECCCCCCCEEEEEECCCCCEEEEEEECCHHHCCCCCCCHHHHHHHHHCCCCCCCCCCHHH
DNQSTEMSISLS
CCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA