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The map label for this gene is dnaE-C [H]

Identifier: 170078017

GI number: 170078017

Start: 1476004

End: 1478652

Strand: Reverse

Name: dnaE-C [H]

Synonym: SYNPCC7002_A1408

Alternate gene names: 170078017

Gene position: 1478652-1476004 (Counterclockwise)

Preceding gene: 170078018

Following gene: 170078015

Centisome position: 49.16

GC content: 51.04

Gene sequence:

>2649_bases
ATGTCTTTTGTCGGTCTCCACATCCACAGTGATTACAGTTTGCTCGATGGCGCGTCCCAGATTAAGCCCCTCATTAAGCG
GGCTGAAGAACTGAAAATGCCGGCGATCGCCTTAACGGATCATGGGGTGATGTACGGGGCGATCGAACTGCTCAAAACCT
GTCGCAATAAACGGATCAAGCCGATCATTGGCAACGAAATGTACGTGATCAACGGCGACATCGAAGACAAAACCCAACGG
TTTAAGAAGTACCATCAGGTCGTTCTGGCGAAAAATACCCAGGGCTACAAAAACCTGGTGAAATTGACCACTATTTCGCA
CCTCAAGGGCTTTCAAGGCAAAGGGATTTTCGCCCGCCCCTGCATTAACAAAGAACTCATTGAGCAACACCACGAAGGGC
TGATTATGACCAGTGCCTGTCTCGGTGGGGAAGTGCCCCAATGTATCCTCAAGGGCGAATATCAGCGGGCGCGGGAAGTG
GCGAAGTGGTACAAAAATATTTTTGGCGATGACTATTACCTCGAAATCCAAGACCATGGCTCCCAGGAAGACCGCATCGT
CAATGTGGAGATCGTCAAAATTGCCCAGGAACTCGACATTAAAATCATCGCCACCAACGACTCCCACTTCATTTCTTGCT
ACGACGTGGAGGCCCACGATGCCCTCCTGTGTATTCAAACCGCAAAATTAATCACCGAAGATAAGCGCCTCCGCTACAGC
GGCACCGAATATCTCAAATCCGCCGATGAGATGCGTAAACTCTTTCGAGATCACCTCGACCCAGGGATTATTGACCAGGC
GATCGCCAATACCCTCGAAGTTGCCGCCAAGGTCGAACCTTACAAAATCCTGGGGGAACCCCGCATTCCCGATTACCCCG
TCCCCGAGGGCCACACCGCTGACAGTTACCTCGAAGCAGTCACCTGGGACGGACTCCTCAAACGCCTCAAATGCAAAACC
CAGGCCGAAGTCGATCCCACCTACAAAGAACGCCTCGAATACGAACTGCAAATGATGCAGCAGATGGGCTTTTCCACGTA
CTTCCTCGTGGTATGGGATTACGTAAAATACGCCAGGGACAATGATATTCCCGTCGGGCCAGGGCGCGGTTCTGCGGCGG
GTTCCCTCGTGGCCTATTCCCTGGGCATTACGAATATTGACCCCATTCACCACAGTCTGCTGTTCGAGCGGTTCCTCAAC
CCCGAACGAAAATCCATGCCGGACGTTGATACGGATTTTTGTATCGAGCGGCGGGACGAAATGATCAAGTATGTCACCGA
AAAATATGGTGAAGACCGGGTCGCACAAATTATTACTTTTAACCGCATGACCTCCAAGGCCGTGCTCAAAGATGTGGCGC
GGGTGCTGGATATTCCCTACGGAGAAGCGGACATGATGGCAAAAATGATCCCCGTGGCCCGGGGCAAACCGGCAAAGCTG
AAGGTGATGATTTCCGACGATACGCCAGAACCAGAATTTAAACGTCGCTACGAAACCGATCCCCAAGTACGCCGCTGGGT
CGATATGGCGATCCGCATCGAAGGAACAAACAAAACCTTTGGGGTTCATGCCGCCGGGGTGGTGATTTCTTCAACGCCCT
TAGATGAAGCGGTACCGCTCCAGCGTAACAATGAAGGGGCGGTGATCACCCAATATTACATGGAAGATGTGGAGGCGATG
GGGCTGCTGAAAATGGATTTTCTCGGCCTAAAAAATCTCACTACCATCAAAAAAGCGGCGGATTTGATCAAAGAATATCG
CCACGTAGAACTGGATCTCGATCAGTTACCCCTCGATGAACGCAAGGCCCTAGAAATCATCAGTAAAGGCCATGCGAAAA
AGTTACCGGGTGATATTGATAAAACCCATGATCTGTTTGGTCGGGGAGATCTAGAGGGGATTTTCCAGCTTGAATCTGAC
GGCATGAAAAAAATTGTCCAGGATTTGCGCCCTTCCGGCATTGAGGACATTTCCTCTGTCCTTGCCCTTTACCGACCTGG
CCCCTTGGATGCGGGCTTAATTCCGATTTTTATCAACCGCAAACATGGCGTCGAAAAGATTGAATATCAGCACGAGCTTT
TGCAGTCGATTTTGAATGAAACCTATGGGGTCTTGGTTTACCAAGAACAGATTATGAAAATGGCCCAGGATTTGGCGGGC
TATTCCCTCGGGGAAGCGGATCTGCTGCGGCGGGCGATGGGGAAAAAGAAAATTGATGAAATGAAAAAACACGAGGCCAA
GTTCGTGGAGGGGGCGGCGACCAATGGGGTTTCGGAGGCGATCGCCAGGGATTTGTTCGACCAGATGGTGAAATTTGCGG
AATATTGCCTCGCCGGGGGCACACCTGTCGTCACCGTTGAATATGGGGTGCTGCCGATCCAAACTATCGTGGAACAGGAA
TTGCTCTGCCATGTGTACAGTGTTGATGCGCAAGGCTTGATTTATGCTCAACTCATTGAACAGTGGCACCAACGGGGCGA
TCGCCTTTTGTATGAATATGAACTGGAAAATGGCCAAATGATTCGGGCGACCCCAGACCATAGATTCCTGACCACCACCG
GGGAACTGCTACCCATTGACGAGATTTTCACCCAAAATTTAGACCTAGCCGCCTGGGCAGTACCAGATTCCCTGCCTAGA
ACTGCTTAG

Upstream 100 bases:

>100_bases
GTGATGTTCCCCTAGAATAATCCCGGCATTTCCCCCGTCATAGTGAAAGGCGATCGCCTAAAATGAGGGTCTACTTCCCC
TACTAGAGTTCCCCCTCGCC

Downstream 100 bases:

>100_bases
GTTTACGGGTTTGGCGATATTCAAACAACAGTAAAGCGGCAACGGCGATCGCAAAAGGCAATAAATAGTACAGACCCCGA
AAAACAATTAAGGTGGCTAA

Product: DNA polymerase III subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 882; Mature: 881

Protein sequence:

>882_residues
MSFVGLHIHSDYSLLDGASQIKPLIKRAEELKMPAIALTDHGVMYGAIELLKTCRNKRIKPIIGNEMYVINGDIEDKTQR
FKKYHQVVLAKNTQGYKNLVKLTTISHLKGFQGKGIFARPCINKELIEQHHEGLIMTSACLGGEVPQCILKGEYQRAREV
AKWYKNIFGDDYYLEIQDHGSQEDRIVNVEIVKIAQELDIKIIATNDSHFISCYDVEAHDALLCIQTAKLITEDKRLRYS
GTEYLKSADEMRKLFRDHLDPGIIDQAIANTLEVAAKVEPYKILGEPRIPDYPVPEGHTADSYLEAVTWDGLLKRLKCKT
QAEVDPTYKERLEYELQMMQQMGFSTYFLVVWDYVKYARDNDIPVGPGRGSAAGSLVAYSLGITNIDPIHHSLLFERFLN
PERKSMPDVDTDFCIERRDEMIKYVTEKYGEDRVAQIITFNRMTSKAVLKDVARVLDIPYGEADMMAKMIPVARGKPAKL
KVMISDDTPEPEFKRRYETDPQVRRWVDMAIRIEGTNKTFGVHAAGVVISSTPLDEAVPLQRNNEGAVITQYYMEDVEAM
GLLKMDFLGLKNLTTIKKAADLIKEYRHVELDLDQLPLDERKALEIISKGHAKKLPGDIDKTHDLFGRGDLEGIFQLESD
GMKKIVQDLRPSGIEDISSVLALYRPGPLDAGLIPIFINRKHGVEKIEYQHELLQSILNETYGVLVYQEQIMKMAQDLAG
YSLGEADLLRRAMGKKKIDEMKKHEAKFVEGAATNGVSEAIARDLFDQMVKFAEYCLAGGTPVVTVEYGVLPIQTIVEQE
LLCHVYSVDAQGLIYAQLIEQWHQRGDRLLYEYELENGQMIRATPDHRFLTTTGELLPIDEIFTQNLDLAAWAVPDSLPR
TA

Sequences:

>Translated_882_residues
MSFVGLHIHSDYSLLDGASQIKPLIKRAEELKMPAIALTDHGVMYGAIELLKTCRNKRIKPIIGNEMYVINGDIEDKTQR
FKKYHQVVLAKNTQGYKNLVKLTTISHLKGFQGKGIFARPCINKELIEQHHEGLIMTSACLGGEVPQCILKGEYQRAREV
AKWYKNIFGDDYYLEIQDHGSQEDRIVNVEIVKIAQELDIKIIATNDSHFISCYDVEAHDALLCIQTAKLITEDKRLRYS
GTEYLKSADEMRKLFRDHLDPGIIDQAIANTLEVAAKVEPYKILGEPRIPDYPVPEGHTADSYLEAVTWDGLLKRLKCKT
QAEVDPTYKERLEYELQMMQQMGFSTYFLVVWDYVKYARDNDIPVGPGRGSAAGSLVAYSLGITNIDPIHHSLLFERFLN
PERKSMPDVDTDFCIERRDEMIKYVTEKYGEDRVAQIITFNRMTSKAVLKDVARVLDIPYGEADMMAKMIPVARGKPAKL
KVMISDDTPEPEFKRRYETDPQVRRWVDMAIRIEGTNKTFGVHAAGVVISSTPLDEAVPLQRNNEGAVITQYYMEDVEAM
GLLKMDFLGLKNLTTIKKAADLIKEYRHVELDLDQLPLDERKALEIISKGHAKKLPGDIDKTHDLFGRGDLEGIFQLESD
GMKKIVQDLRPSGIEDISSVLALYRPGPLDAGLIPIFINRKHGVEKIEYQHELLQSILNETYGVLVYQEQIMKMAQDLAG
YSLGEADLLRRAMGKKKIDEMKKHEAKFVEGAATNGVSEAIARDLFDQMVKFAEYCLAGGTPVVTVEYGVLPIQTIVEQE
LLCHVYSVDAQGLIYAQLIEQWHQRGDRLLYEYELENGQMIRATPDHRFLTTTGELLPIDEIFTQNLDLAAWAVPDSLPR
TA
>Mature_881_residues
SFVGLHIHSDYSLLDGASQIKPLIKRAEELKMPAIALTDHGVMYGAIELLKTCRNKRIKPIIGNEMYVINGDIEDKTQRF
KKYHQVVLAKNTQGYKNLVKLTTISHLKGFQGKGIFARPCINKELIEQHHEGLIMTSACLGGEVPQCILKGEYQRAREVA
KWYKNIFGDDYYLEIQDHGSQEDRIVNVEIVKIAQELDIKIIATNDSHFISCYDVEAHDALLCIQTAKLITEDKRLRYSG
TEYLKSADEMRKLFRDHLDPGIIDQAIANTLEVAAKVEPYKILGEPRIPDYPVPEGHTADSYLEAVTWDGLLKRLKCKTQ
AEVDPTYKERLEYELQMMQQMGFSTYFLVVWDYVKYARDNDIPVGPGRGSAAGSLVAYSLGITNIDPIHHSLLFERFLNP
ERKSMPDVDTDFCIERRDEMIKYVTEKYGEDRVAQIITFNRMTSKAVLKDVARVLDIPYGEADMMAKMIPVARGKPAKLK
VMISDDTPEPEFKRRYETDPQVRRWVDMAIRIEGTNKTFGVHAAGVVISSTPLDEAVPLQRNNEGAVITQYYMEDVEAMG
LLKMDFLGLKNLTTIKKAADLIKEYRHVELDLDQLPLDERKALEIISKGHAKKLPGDIDKTHDLFGRGDLEGIFQLESDG
MKKIVQDLRPSGIEDISSVLALYRPGPLDAGLIPIFINRKHGVEKIEYQHELLQSILNETYGVLVYQEQIMKMAQDLAGY
SLGEADLLRRAMGKKKIDEMKKHEAKFVEGAATNGVSEAIARDLFDQMVKFAEYCLAGGTPVVTVEYGVLPIQTIVEQEL
LCHVYSVDAQGLIYAQLIEQWHQRGDRLLYEYELENGQMIRATPDHRFLTTTGELLPIDEIFTQNLDLAAWAVPDSLPRT
A

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase [H]

COG id: COG0587

COG function: function code L; DNA polymerase III, alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA polymerase type-C family. DnaE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786381, Length=825, Percent_Identity=39.5151515151515, Blast_Score=575, Evalue=1e-165,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011708
- InterPro:   IPR003587
- InterPro:   IPR006141
- InterPro:   IPR004365
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR016195
- InterPro:   IPR004805 [H]

Pfam domain/function: PF07733 DNA_pol3_alpha; PF02811 PHP; PF01336 tRNA_anti [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 100012; Mature: 99881

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS50817 INTEIN_N_TER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFVGLHIHSDYSLLDGASQIKPLIKRAEELKMPAIALTDHGVMYGAIELLKTCRNKRIK
CCEEEEEEECCCHHHCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCC
PIIGNEMYVINGDIEDKTQRFKKYHQVVLAKNTQGYKNLVKLTTISHLKGFQGKGIFARP
EEECCEEEEEECCCCHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHCCCCCCCEEECC
CINKELIEQHHEGLIMTSACLGGEVPQCILKGEYQRAREVAKWYKNIFGDDYYLEIQDHG
CCCHHHHHHHCCCEEEEHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEECCC
SQEDRIVNVEIVKIAQELDIKIIATNDSHFISCYDVEAHDALLCIQTAKLITEDKRLRYS
CCCCEEEEHHHEEEHHHCCEEEEEECCCCEEEEEECCCCCCEEHHHHHHHHHHCCHHCCC
GTEYLKSADEMRKLFRDHLDPGIIDQAIANTLEVAAKVEPYKILGEPRIPDYPVPEGHTA
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCH
DSYLEAVTWDGLLKRLKCKTQAEVDPTYKERLEYELQMMQQMGFSTYFLVVWDYVKYARD
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
NDIPVGPGRGSAAGSLVAYSLGITNIDPIHHSLLFERFLNPERKSMPDVDTDFCIERRDE
CCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHH
MIKYVTEKYGEDRVAQIITFNRMTSKAVLKDVARVLDIPYGEADMMAKMIPVARGKPAKL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEE
KVMISDDTPEPEFKRRYETDPQVRRWVDMAIRIEGTNKTFGVHAAGVVISSTPLDEAVPL
EEEECCCCCCHHHHHHCCCCHHHHHHEEEEEEEECCCCEEEEEECCEEEECCCCCCCCCC
QRNNEGAVITQYYMEDVEAMGLLKMDFLGLKNLTTIKKAADLIKEYRHVELDLDQLPLDE
CCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCH
RKALEIISKGHAKKLPGDIDKTHDLFGRGDLEGIFQLESDGMKKIVQDLRPSGIEDISSV
HHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCEEEECCCHHHHHHHHCCCCCHHHHHHH
LALYRPGPLDAGLIPIFINRKHGVEKIEYQHELLQSILNETYGVLVYQEQIMKMAQDLAG
HHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCEEEEHHHHHHHHHHHCC
YSLGEADLLRRAMGKKKIDEMKKHEAKFVEGAATNGVSEAIARDLFDQMVKFAEYCLAGG
CCCCHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
TPVVTVEYGVLPIQTIVEQELLCHVYSVDAQGLIYAQLIEQWHQRGDRLLYEYELENGQM
CEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCEE
IRATPDHRFLTTTGELLPIDEIFTQNLDLAAWAVPDSLPRTA
EEECCCCCEEECCCCCCCHHHHHHCCCCEEEEECCCCCCCCC
>Mature Secondary Structure 
SFVGLHIHSDYSLLDGASQIKPLIKRAEELKMPAIALTDHGVMYGAIELLKTCRNKRIK
CEEEEEEECCCHHHCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCC
PIIGNEMYVINGDIEDKTQRFKKYHQVVLAKNTQGYKNLVKLTTISHLKGFQGKGIFARP
EEECCEEEEEECCCCHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHCCCCCCCEEECC
CINKELIEQHHEGLIMTSACLGGEVPQCILKGEYQRAREVAKWYKNIFGDDYYLEIQDHG
CCCHHHHHHHCCCEEEEHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEECCC
SQEDRIVNVEIVKIAQELDIKIIATNDSHFISCYDVEAHDALLCIQTAKLITEDKRLRYS
CCCCEEEEHHHEEEHHHCCEEEEEECCCCEEEEEECCCCCCEEHHHHHHHHHHCCHHCCC
GTEYLKSADEMRKLFRDHLDPGIIDQAIANTLEVAAKVEPYKILGEPRIPDYPVPEGHTA
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCH
DSYLEAVTWDGLLKRLKCKTQAEVDPTYKERLEYELQMMQQMGFSTYFLVVWDYVKYARD
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
NDIPVGPGRGSAAGSLVAYSLGITNIDPIHHSLLFERFLNPERKSMPDVDTDFCIERRDE
CCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHH
MIKYVTEKYGEDRVAQIITFNRMTSKAVLKDVARVLDIPYGEADMMAKMIPVARGKPAKL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEE
KVMISDDTPEPEFKRRYETDPQVRRWVDMAIRIEGTNKTFGVHAAGVVISSTPLDEAVPL
EEEECCCCCCHHHHHHCCCCHHHHHHEEEEEEEECCCCEEEEEECCEEEECCCCCCCCCC
QRNNEGAVITQYYMEDVEAMGLLKMDFLGLKNLTTIKKAADLIKEYRHVELDLDQLPLDE
CCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCH
RKALEIISKGHAKKLPGDIDKTHDLFGRGDLEGIFQLESDGMKKIVQDLRPSGIEDISSV
HHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCEEEECCCHHHHHHHHCCCCCHHHHHHH
LALYRPGPLDAGLIPIFINRKHGVEKIEYQHELLQSILNETYGVLVYQEQIMKMAQDLAG
HHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCEEEEHHHHHHHHHHHCC
YSLGEADLLRRAMGKKKIDEMKKHEAKFVEGAATNGVSEAIARDLFDQMVKFAEYCLAGG
CCCCHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
TPVVTVEYGVLPIQTIVEQELLCHVYSVDAQGLIYAQLIEQWHQRGDRLLYEYELENGQM
CEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCEE
IRATPDHRFLTTTGELLPIDEIFTQNLDLAAWAVPDSLPRTA
EEECCCCCEEECCCCCCCHHHHHHCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231; 9689062; 10734038; 11170467 [H]