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The map label for this gene is ppx [H]

Identifier: 170078010

GI number: 170078010

Start: 1467488

End: 1469128

Strand: Direct

Name: ppx [H]

Synonym: SYNPCC7002_A1401

Alternate gene names: 170078010

Gene position: 1467488-1469128 (Clockwise)

Preceding gene: 170078008

Following gene: 170078011

Centisome position: 48.79

GC content: 49.73

Gene sequence:

>1641_bases
ATGGCTACTTCCGTCTATCAGCTTAAAACGAATTCCACTCAATTTGCGAATGTCACCCAAGGGGAGGACTGTACCCTAGC
AGCGATTGATATCGGCACCAACTCAATTCACATGGTGATTGTCAAAATTCAACCCAGCCTGCCCGCATTTACAATTGTGG
CCCGGGAAAAAGATACGGTGCGCCTCGGTCATCGCGATCGCCTCACAGGAAACCTGACGGAAGCCGCCATGGATCGTTCT
TTAAATGCCCTCCGTCGTTGTCAGGATCTAGCGACGAGTTTTCAGGTGGATTCTTTAGTAGCAGTGGCAACCAGTGCCGT
GCGAGAAGCCCCCAACGGTCGAGAATTTTTACAACGGATTGAAGCAGAATTAGGGTTAGAAGTTGATCTAATCTCCGGCC
AAGAAGAAGCGCGCCGTATCTACCTCGGTGTTTTATCAGCCGTTGACTTTAACCAACAACCCCATGTTTTGATTGATATT
GGGGGCGGTTCGACAGAAATTAGCTTGGTGGAAAGCCATGAAGCACGCTTTCTTAGCAGCACAAAGGTGGGAGCGGTGCG
GTTAACCCAGGACTTTGTGAATACTGATCCGATTAGTAACCGAGAATTTGCGGCCCTACAAGCTTATATTCGGGGGATGT
TAGAGCGTCCCATTGAAGAACTACAAGAGCATCTTTTCCCGGAAGAACAGGTACAAATGATCGGGACCTCTGGCACCATT
GAAACCTTGGCAGCAATGCACGCGATGGCCAATTTAGGAAATGTGCCGAGTCCCCTCCATGGCTATACGTTTTCGCGTCA
GGATTTGAGCAAACTGATTCAACAGATGCGGGAGCTTAATTGTCGGGAGCGCTCAAATTTACCAGGAATGTCCGATAAGC
GCGCAGAAATTATTCTGGCAGGGGCAATCATCCTCCAAGAAGCGATGGATCTATTGCAGCTGAAAAAAATTACCCTCTGT
GAACGGGCGTTGCGGGAAGGGGTGATCGTCGACTGGATGCTTTCCCATGGTTTGATTGAAAGTCGCCTGCAATACCAAAG
TTCGATTCGGGAACGGAGTGTGATGGCGATCGCCAAAAAATATCGCGTTGATTTGGTCGCCAGTAAACGCACTGCCGTAT
TTTCCCTGAGTCTCTTTGATCAGCTCCAGGGGGGGCTGCACCAATGGGACACCGAAGCGAGGGAGATGCTCTGGGCGGCG
GCGATTCTCCATAACTGTGGCCTTTACATTAGCCATGCGGCTCACCATAAACATTCCTACTATCTGATTCGTAATGCAGA
GCTCCTCGGCTTTAATGAAACCCAATTAGAAATCGTCGCGAACCTCGCCCGCTACCACCGCAAAAGCAAGCCGAAGAAAA
AACACGAAAATTATCAAAATCTCATCCACAAAGAACACCGACAGATGGTGAGTGAGTTGAGTGCGATCATGCGGCTTGCG
GTGGCCCTTGACCGACGCCAGGTAGGGGCGATCGCCGAAATTCAGTGTGACTTTGATGCGAAACAACGCCTACTCACCCT
CAAGCTAATCCCAACCCATAGGGATGATGCCTGCGAACTAGAGCTCTGGAGTTTAAACTATAACAAGGAGATCTTTGAAG
AAGAATTTGCAGTGACCGTGGCCGCCCATCTATGCCCCTAA

Upstream 100 bases:

>100_bases
GAAACCATAGATGTTCAACGAAGAGATGTCATAAAAAATCAGTAAATCGGAGGTAATCCTTAATAATAGAGAAGTCAGCA
AAGATGACAGACATAAATCT

Downstream 100 bases:

>100_bases
ACTCTTAGAATAGTTAATCCACGTTAATCTTTTCTTAAAATCCCTGTACCAATGCGGCGGCGATCGCCCCTGTGACTAGC
CCAGATAGCCCCTTACTGCT

Product: exopolyphosphatase

Products: NA

Alternate protein names: ExopolyPase; Metaphosphatase [H]

Number of amino acids: Translated: 546; Mature: 545

Protein sequence:

>546_residues
MATSVYQLKTNSTQFANVTQGEDCTLAAIDIGTNSIHMVIVKIQPSLPAFTIVAREKDTVRLGHRDRLTGNLTEAAMDRS
LNALRRCQDLATSFQVDSLVAVATSAVREAPNGREFLQRIEAELGLEVDLISGQEEARRIYLGVLSAVDFNQQPHVLIDI
GGGSTEISLVESHEARFLSSTKVGAVRLTQDFVNTDPISNREFAALQAYIRGMLERPIEELQEHLFPEEQVQMIGTSGTI
ETLAAMHAMANLGNVPSPLHGYTFSRQDLSKLIQQMRELNCRERSNLPGMSDKRAEIILAGAIILQEAMDLLQLKKITLC
ERALREGVIVDWMLSHGLIESRLQYQSSIRERSVMAIAKKYRVDLVASKRTAVFSLSLFDQLQGGLHQWDTEAREMLWAA
AILHNCGLYISHAAHHKHSYYLIRNAELLGFNETQLEIVANLARYHRKSKPKKKHENYQNLIHKEHRQMVSELSAIMRLA
VALDRRQVGAIAEIQCDFDAKQRLLTLKLIPTHRDDACELELWSLNYNKEIFEEEFAVTVAAHLCP

Sequences:

>Translated_546_residues
MATSVYQLKTNSTQFANVTQGEDCTLAAIDIGTNSIHMVIVKIQPSLPAFTIVAREKDTVRLGHRDRLTGNLTEAAMDRS
LNALRRCQDLATSFQVDSLVAVATSAVREAPNGREFLQRIEAELGLEVDLISGQEEARRIYLGVLSAVDFNQQPHVLIDI
GGGSTEISLVESHEARFLSSTKVGAVRLTQDFVNTDPISNREFAALQAYIRGMLERPIEELQEHLFPEEQVQMIGTSGTI
ETLAAMHAMANLGNVPSPLHGYTFSRQDLSKLIQQMRELNCRERSNLPGMSDKRAEIILAGAIILQEAMDLLQLKKITLC
ERALREGVIVDWMLSHGLIESRLQYQSSIRERSVMAIAKKYRVDLVASKRTAVFSLSLFDQLQGGLHQWDTEAREMLWAA
AILHNCGLYISHAAHHKHSYYLIRNAELLGFNETQLEIVANLARYHRKSKPKKKHENYQNLIHKEHRQMVSELSAIMRLA
VALDRRQVGAIAEIQCDFDAKQRLLTLKLIPTHRDDACELELWSLNYNKEIFEEEFAVTVAAHLCP
>Mature_545_residues
ATSVYQLKTNSTQFANVTQGEDCTLAAIDIGTNSIHMVIVKIQPSLPAFTIVAREKDTVRLGHRDRLTGNLTEAAMDRSL
NALRRCQDLATSFQVDSLVAVATSAVREAPNGREFLQRIEAELGLEVDLISGQEEARRIYLGVLSAVDFNQQPHVLIDIG
GGSTEISLVESHEARFLSSTKVGAVRLTQDFVNTDPISNREFAALQAYIRGMLERPIEELQEHLFPEEQVQMIGTSGTIE
TLAAMHAMANLGNVPSPLHGYTFSRQDLSKLIQQMRELNCRERSNLPGMSDKRAEIILAGAIILQEAMDLLQLKKITLCE
RALREGVIVDWMLSHGLIESRLQYQSSIRERSVMAIAKKYRVDLVASKRTAVFSLSLFDQLQGGLHQWDTEAREMLWAAA
ILHNCGLYISHAAHHKHSYYLIRNAELLGFNETQLEIVANLARYHRKSKPKKKHENYQNLIHKEHRQMVSELSAIMRLAV
ALDRRQVGAIAEIQCDFDAKQRLLTLKLIPTHRDDACELELWSLNYNKEIFEEEFAVTVAAHLCP

Specific function: Degradation of inorganic polyphosphates. Orthophosphate is released progressively from the ends of polyphosphate [H]

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI1788848, Length=432, Percent_Identity=31.9444444444444, Blast_Score=185, Evalue=8e-48,
Organism=Escherichia coli, GI48994966, Length=494, Percent_Identity=28.7449392712551, Blast_Score=150, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022371
- InterPro:   IPR003695 [H]

Pfam domain/function: PF02541 Ppx-GppA [H]

EC number: =3.6.1.11 [H]

Molecular weight: Translated: 61483; Mature: 61352

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00435 PEROXIDASE_1 ; PS00329 HSP70_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATSVYQLKTNSTQFANVTQGEDCTLAAIDIGTNSIHMVIVKIQPSLPAFTIVAREKDTV
CCCCEEEEECCCCEECCCCCCCCCEEEEEEECCCCEEEEEEEECCCCCEEEEEECCCCCE
RLGHRDRLTGNLTEAAMDRSLNALRRCQDLATSFQVDSLVAVATSAVREAPNGREFLQRI
ECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
EAELGLEVDLISGQEEARRIYLGVLSAVDFNQQPHVLIDIGGGSTEISLVESHEARFLSS
HHHHCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEECCHHHHHHC
TKVGAVRLTQDFVNTDPISNREFAALQAYIRGMLERPIEELQEHLFPEEQVQMIGTSGTI
CCCCEEEEEHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHH
ETLAAMHAMANLGNVPSPLHGYTFSRQDLSKLIQQMRELNCRERSNLPGMSDKRAEIILA
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHEEEH
GAIILQEAMDLLQLKKITLCERALREGVIVDWMLSHGLIESRLQYQSSIRERSVMAIAKK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRVDLVASKRTAVFSLSLFDQLQGGLHQWDTEAREMLWAAAILHNCGLYISHAAHHKHSY
HHHEEEECCCHHEEEHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEHHHCCCCCE
YLIRNAELLGFNETQLEIVANLARYHRKSKPKKKHENYQNLIHKEHRQMVSELSAIMRLA
EEEECCEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VALDRRQVGAIAEIQCDFDAKQRLLTLKLIPTHRDDACELELWSLNYNKEIFEEEFAVTV
HHHHHHHCCCEEEEEECCCCCCCEEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHH
AAHLCP
HHHCCC
>Mature Secondary Structure 
ATSVYQLKTNSTQFANVTQGEDCTLAAIDIGTNSIHMVIVKIQPSLPAFTIVAREKDTV
CCCEEEEECCCCEECCCCCCCCCEEEEEEECCCCEEEEEEEECCCCCEEEEEECCCCCE
RLGHRDRLTGNLTEAAMDRSLNALRRCQDLATSFQVDSLVAVATSAVREAPNGREFLQRI
ECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
EAELGLEVDLISGQEEARRIYLGVLSAVDFNQQPHVLIDIGGGSTEISLVESHEARFLSS
HHHHCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEECCHHHHHHC
TKVGAVRLTQDFVNTDPISNREFAALQAYIRGMLERPIEELQEHLFPEEQVQMIGTSGTI
CCCCEEEEEHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHH
ETLAAMHAMANLGNVPSPLHGYTFSRQDLSKLIQQMRELNCRERSNLPGMSDKRAEIILA
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHEEEH
GAIILQEAMDLLQLKKITLCERALREGVIVDWMLSHGLIESRLQYQSSIRERSVMAIAKK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRVDLVASKRTAVFSLSLFDQLQGGLHQWDTEAREMLWAAAILHNCGLYISHAAHHKHSY
HHHEEEECCCHHEEEHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEHHHCCCCCE
YLIRNAELLGFNETQLEIVANLARYHRKSKPKKKHENYQNLIHKEHRQMVSELSAIMRLA
EEEECCEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VALDRRQVGAIAEIQCDFDAKQRLLTLKLIPTHRDDACELELWSLNYNKEIFEEEFAVTV
HHHHHHHCCCEEEEEECCCCCCCEEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHH
AAHLCP
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]