Click here to switch to the map view.

The map label for this gene is map [C]

Identifier: 170077892

GI number: 170077892

Start: 1324633

End: 1325358

Strand: Reverse

Name: map [C]

Synonym: SYNPCC7002_A1277

Alternate gene names: 170077892

Gene position: 1325358-1324633 (Counterclockwise)

Preceding gene: 170077894

Following gene: 170077890

Centisome position: 44.06

GC content: 50.14

Gene sequence:

>726_bases
ATGCGCAATGCGGGACGGCTAGCGGCGCAACTCCTTGATTACCTAGAGCCTCTGGTTAAACCGGGAGTGACGACCCTCGA
ATTGAACGATGCAGCGGAGGAATGGACCCAAAAACACGGTGCAAAAAGCGCCCCCCTCGGTTATGGCAAGAGTAACCCTT
ACCCAAAATCTATTTGTACCAGTGTCAATGAAGTAATTTGTCACGGCATTCCCAGTAAGAAAAAAGTCCTCAAAGACGGC
GACATCATCAATATCGATGTGACCCCCATTCTCGATGGCTACCATGGTGATACGTCTCGGACTTTTTTTGTGGGCACCCC
AGCACCCAGGGTTAAAAAATTAGTCGAAGTAACGGAAAAATGTCTGTACATCGGCATTGAAGCAGCTCAACCCAACGGTC
GCATCGGTGATATTGGGGCGGCGATCCAAGAATATGCCGAATCCCAAGGCTATTCAGTCGTGCGTGATTTTGTCGGTCAT
GGCATTAGTAATGTCTTCCACACAGAGCCCCAGGTTCCCCACTACGGTAAACGCGGTAAGGGTACCAAAATTCGTCCGGG
GATGGTTTTTACCATTGAACCAATGATCAATGAAGGCACCTATGAGAGCCAGCTACTCGGTGATGGTTGGACGGCGGTGA
CCAAGGACGGTAAGCTCTCGGCCCAGTTTGAACATACGATTGCGATCACCCCAGAAGGGCCAGAAATTTTAACCCTGTCG
GCATAA

Upstream 100 bases:

>100_bases
GGCTGTTACAATAAACCTCTGATAATTCTGTTGGTCTTACAAGCAATAAACTCCCATGGGTAAAGGCATCGTTCTGCTAT
CAAAACGAGAAATTGAAAAA

Downstream 100 bases:

>100_bases
AGGGTGTGATGGGATAGCTTGAAAACCTGAGATACCAACAAAAAAGACCCCAAGTGGGGTCTTTTCGCAATTAGTTTTAG
AGTTTAAACATAAGCGTCTA

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MRNAGRLAAQLLDYLEPLVKPGVTTLELNDAAEEWTQKHGAKSAPLGYGKSNPYPKSICTSVNEVICHGIPSKKKVLKDG
DIINIDVTPILDGYHGDTSRTFFVGTPAPRVKKLVEVTEKCLYIGIEAAQPNGRIGDIGAAIQEYAESQGYSVVRDFVGH
GISNVFHTEPQVPHYGKRGKGTKIRPGMVFTIEPMINEGTYESQLLGDGWTAVTKDGKLSAQFEHTIAITPEGPEILTLS
A

Sequences:

>Translated_241_residues
MRNAGRLAAQLLDYLEPLVKPGVTTLELNDAAEEWTQKHGAKSAPLGYGKSNPYPKSICTSVNEVICHGIPSKKKVLKDG
DIINIDVTPILDGYHGDTSRTFFVGTPAPRVKKLVEVTEKCLYIGIEAAQPNGRIGDIGAAIQEYAESQGYSVVRDFVGH
GISNVFHTEPQVPHYGKRGKGTKIRPGMVFTIEPMINEGTYESQLLGDGWTAVTKDGKLSAQFEHTIAITPEGPEILTLS
A
>Mature_241_residues
MRNAGRLAAQLLDYLEPLVKPGVTTLELNDAAEEWTQKHGAKSAPLGYGKSNPYPKSICTSVNEVICHGIPSKKKVLKDG
DIINIDVTPILDGYHGDTSRTFFVGTPAPRVKKLVEVTEKCLYIGIEAAQPNGRIGDIGAAIQEYAESQGYSVVRDFVGH
GISNVFHTEPQVPHYGKRGKGTKIRPGMVFTIEPMINEGTYESQLLGDGWTAVTKDGKLSAQFEHTIAITPEGPEILTLS
A

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=238, Percent_Identity=49.1596638655462, Blast_Score=234, Evalue=7e-62,
Organism=Homo sapiens, GI40385867, Length=238, Percent_Identity=44.1176470588235, Blast_Score=190, Evalue=1e-48,
Organism=Escherichia coli, GI1786364, Length=240, Percent_Identity=52.9166666666667, Blast_Score=263, Evalue=6e-72,
Organism=Caenorhabditis elegans, GI71996291, Length=239, Percent_Identity=46.0251046025105, Blast_Score=208, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6323273, Length=239, Percent_Identity=45.6066945606695, Blast_Score=218, Evalue=9e-58,
Organism=Drosophila melanogaster, GI21355531, Length=238, Percent_Identity=48.7394957983193, Blast_Score=216, Evalue=1e-56,
Organism=Drosophila melanogaster, GI24583427, Length=238, Percent_Identity=46.6386554621849, Blast_Score=200, Evalue=6e-52,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 26102; Mature: 26102

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNAGRLAAQLLDYLEPLVKPGVTTLELNDAAEEWTQKHGAKSAPLGYGKSNPYPKSICT
CCCHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHH
SVNEVICHGIPSKKKVLKDGDIINIDVTPILDGYHGDTSRTFFVGTPAPRVKKLVEVTEK
HHHHHHHCCCCCHHHHHCCCCEEEEEECEEECCCCCCCCCEEEEECCCHHHHHHHHHHHH
CLYIGIEAAQPNGRIGDIGAAIQEYAESQGYSVVRDFVGHGISNVFHTEPQVPHYGKRGK
HEEEEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHCCCCCCCCCCCCCC
GTKIRPGMVFTIEPMINEGTYESQLLGDGWTAVTKDGKLSAQFEHTIAITPEGPEILTLS
CCEECCCEEEEEECCCCCCCCHHHHCCCCCEEEECCCCEEEEEEEEEEECCCCCCEEEEC
A
C
>Mature Secondary Structure
MRNAGRLAAQLLDYLEPLVKPGVTTLELNDAAEEWTQKHGAKSAPLGYGKSNPYPKSICT
CCCHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHH
SVNEVICHGIPSKKKVLKDGDIINIDVTPILDGYHGDTSRTFFVGTPAPRVKKLVEVTEK
HHHHHHHCCCCCHHHHHCCCCEEEEEECEEECCCCCCCCCEEEEECCCHHHHHHHHHHHH
CLYIGIEAAQPNGRIGDIGAAIQEYAESQGYSVVRDFVGHGISNVFHTEPQVPHYGKRGK
HEEEEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHCCCCCCCCCCCCCC
GTKIRPGMVFTIEPMINEGTYESQLLGDGWTAVTKDGKLSAQFEHTIAITPEGPEILTLS
CCEECCCEEEEEECCCCCCCCHHHHCCCCCEEEECCCCEEEEEEEEEEECCCCCCEEEEC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]