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The map label for this gene is thiL [H]

Identifier: 170077870

GI number: 170077870

Start: 1296283

End: 1297275

Strand: Direct

Name: thiL [H]

Synonym: SYNPCC7002_A1254

Alternate gene names: 170077870

Gene position: 1296283-1297275 (Clockwise)

Preceding gene: 170077868

Following gene: 170077871

Centisome position: 43.09

GC content: 55.59

Gene sequence:

>993_bases
ATGACGGCAGGAAAATGTCTCAAGGATTTTGGGGAAGCGGAGATTCTCCAGCGGCTGCAGCGGTTTTGTCCAGCAGAAAT
TATCGGCGATGATGGGGCAGTTTTAACGTTCCCCCCTGGCCAGAATTTAGTCGTGACGACGGATGTGCTGGTGGATGGCG
TCCATTTTGGCGATCGCACGATGCCCCCAGAGAAAGTAGGCTGGCGAGCAGTGGCGGCAAATTTATCGGATTTAGCAGCG
ATGGGGGCCACACCAATCGGCATTACCGTGGGTTTATCTCTGCCTCCTGAAACACCGATTTTGTGGCTCGATCAGCTTTA
TCAAGGGTTAGCTGCCTGTTTAGGTCGTTATGGTACGCCTTTAGTCGGTGGGGATCTAACGCGATCGCCGGTGAAAACCA
TCGGCATTACGGCCTTTGGGGTGGTGTCACCGCACCGTGCGATTCAGCGCAGTAGCGCGAAAGTGGGCGATGTGATTCTC
GTTACGGGTTGCCATGGGGATTCCCGTGCGGGCCTGGAATTGCTGCTCCATACCAATGCTCGCTCTCAAACTTTATCGAT
AGGCGATCGCCAAGCCTTGATCCGCGCCCACCAAACGCCCCAACCCCGCCTGGATGTGCTGCCGCATTTAAACTCCTCAG
ATTCGCCCCCAGCAGGGATGGATAGTAGCGATGGTTTGGCCGATGCCGTGCTGCAAATTTGTCAACGCAGTGGTGTCGGT
GCCGTAGTGGAAGCAGAGAAAATCCCCTTGTCCCCGGCCCTTCGGCGTTATCAAGATCCAGAAACGGCTTTGCGGTGGGC
TTTGTACGGTGGCGAAGATTTTGAACTGGTGCTTTGTCTCCCCCCGATGGCGGCGGAACGGCTCCTGGCCAAGCTTCCAG
GTCAAGGGGCGATTATCGGCCAGATTACCGCCGAGCAAACGGTGGCGATCGCCAATGGTGCAGGCCAAACCATGCCCTTA
AGCCAAACTCAAACTTTTCAACACTTTGCCTAA

Upstream 100 bases:

>100_bases
ACTATTTCCTCGATTTTACAAAAAAAGTAATGGATTTAGTCAATTACTATACTTTTTCAGAGCATAAACAATTCATCATG
GAGGGCTTGGCGAGAAAACG

Downstream 100 bases:

>100_bases
CGTTTTCCTTGCCGAGATCCCCAGCCGAATGTGACAAAATAAGGCTGCAATCTTCTCCATGTCGGCCCTCCATGAATCGC
CTGAAAACCGCTGCCACTTA

Product: thiamine monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MTAGKCLKDFGEAEILQRLQRFCPAEIIGDDGAVLTFPPGQNLVVTTDVLVDGVHFGDRTMPPEKVGWRAVAANLSDLAA
MGATPIGITVGLSLPPETPILWLDQLYQGLAACLGRYGTPLVGGDLTRSPVKTIGITAFGVVSPHRAIQRSSAKVGDVIL
VTGCHGDSRAGLELLLHTNARSQTLSIGDRQALIRAHQTPQPRLDVLPHLNSSDSPPAGMDSSDGLADAVLQICQRSGVG
AVVEAEKIPLSPALRRYQDPETALRWALYGGEDFELVLCLPPMAAERLLAKLPGQGAIIGQITAEQTVAIANGAGQTMPL
SQTQTFQHFA

Sequences:

>Translated_330_residues
MTAGKCLKDFGEAEILQRLQRFCPAEIIGDDGAVLTFPPGQNLVVTTDVLVDGVHFGDRTMPPEKVGWRAVAANLSDLAA
MGATPIGITVGLSLPPETPILWLDQLYQGLAACLGRYGTPLVGGDLTRSPVKTIGITAFGVVSPHRAIQRSSAKVGDVIL
VTGCHGDSRAGLELLLHTNARSQTLSIGDRQALIRAHQTPQPRLDVLPHLNSSDSPPAGMDSSDGLADAVLQICQRSGVG
AVVEAEKIPLSPALRRYQDPETALRWALYGGEDFELVLCLPPMAAERLLAKLPGQGAIIGQITAEQTVAIANGAGQTMPL
SQTQTFQHFA
>Mature_329_residues
TAGKCLKDFGEAEILQRLQRFCPAEIIGDDGAVLTFPPGQNLVVTTDVLVDGVHFGDRTMPPEKVGWRAVAANLSDLAAM
GATPIGITVGLSLPPETPILWLDQLYQGLAACLGRYGTPLVGGDLTRSPVKTIGITAFGVVSPHRAIQRSSAKVGDVILV
TGCHGDSRAGLELLLHTNARSQTLSIGDRQALIRAHQTPQPRLDVLPHLNSSDSPPAGMDSSDGLADAVLQICQRSGVGA
VVEAEKIPLSPALRRYQDPETALRWALYGGEDFELVLCLPPMAAERLLAKLPGQGAIIGQITAEQTVAIANGAGQTMPLS
QTQTFQHFA

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=309, Percent_Identity=40.453074433657, Blast_Score=174, Evalue=9e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 34857; Mature: 34726

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAGKCLKDFGEAEILQRLQRFCPAEIIGDDGAVLTFPPGQNLVVTTDVLVDGVHFGDRT
CCHHHHHHHCCHHHHHHHHHHHCCCEEECCCCCEEEECCCCCEEEEHHHEEECEECCCCC
MPPEKVGWRAVAANLSDLAAMGATPIGITVGLSLPPETPILWLDQLYQGLAACLGRYGTP
CCHHHHCHHHHHHCHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCC
LVGGDLTRSPVKTIGITAFGVVSPHRAIQRSSAKVGDVILVTGCHGDSRAGLELLLHTNA
CCCCCCCCCCHHHHCEEEEECCCHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEECCC
RSQTLSIGDRQALIRAHQTPQPRLDVLPHLNSSDSPPAGMDSSDGLADAVLQICQRSGVG
CCCEEECCHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCC
AVVEAEKIPLSPALRRYQDPETALRWALYGGEDFELVLCLPPMAAERLLAKLPGQGAIIG
EEEECCCCCCCHHHHHCCCHHHHHEEEEECCCCCEEEEECCCHHHHHHHHHCCCCCEEEE
QITAEQTVAIANGAGQTMPLSQTQTFQHFA
EECCCCEEEEECCCCCCCCCCCCCHHHHCC
>Mature Secondary Structure 
TAGKCLKDFGEAEILQRLQRFCPAEIIGDDGAVLTFPPGQNLVVTTDVLVDGVHFGDRT
CHHHHHHHCCHHHHHHHHHHHCCCEEECCCCCEEEECCCCCEEEEHHHEEECEECCCCC
MPPEKVGWRAVAANLSDLAAMGATPIGITVGLSLPPETPILWLDQLYQGLAACLGRYGTP
CCHHHHCHHHHHHCHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCC
LVGGDLTRSPVKTIGITAFGVVSPHRAIQRSSAKVGDVILVTGCHGDSRAGLELLLHTNA
CCCCCCCCCCHHHHCEEEEECCCHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEECCC
RSQTLSIGDRQALIRAHQTPQPRLDVLPHLNSSDSPPAGMDSSDGLADAVLQICQRSGVG
CCCEEECCHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCC
AVVEAEKIPLSPALRRYQDPETALRWALYGGEDFELVLCLPPMAAERLLAKLPGQGAIIG
EEEECCCCCCCHHHHHCCCHHHHHEEEEECCCCCEEEEECCCHHHHHHHHHCCCCCEEEE
QITAEQTVAIANGAGQTMPLSQTQTFQHFA
EECCCCEEEEECCCCCCCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA