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The map label for this gene is clpP [H]

Identifier: 170077811

GI number: 170077811

Start: 1238840

End: 1239439

Strand: Direct

Name: clpP [H]

Synonym: SYNPCC7002_A1194

Alternate gene names: 170077811

Gene position: 1238840-1239439 (Clockwise)

Preceding gene: 170077810

Following gene: 170077815

Centisome position: 41.18

GC content: 49.33

Gene sequence:

>600_bases
ATGCCCATCGGTGTACCCAAAGTTCCCTATCAAATGCCCGGTCAGCCCTATTCTGACTGGATCAATATCTATGACCGTTT
GTACCGTGAACGGATTATTTTCCTCGGTCGGGGTGTCAATGATGCTTTGGCAAACCAGATTATTGCCATCATGCTTTACC
TCGATTCTGAAGATCCCAGCAAGCCGATCTATCTCTACATCAACTCCCCCGGTGGCTCAGTGACAGCGGGTCTGGCGATT
TACGACACGATGAAACACATCAAGTCGGAAGTAGTCACCATTTGTGTGGGCTTAGCGGCTTCTATGGGGGCGTTTTTGTT
GTCTGCGGGCACGAAAGGGAAGCGTCTGGCCCTGCCCCACTCCCGGATTATGATCCACCAACCCCTCGGTGGGATCCAAG
GTCGTCGTCAAGCGACAGATATTGACATTGAAGCCAAGGAAATTATCCGCATTAAGCATCAACTCAATGAATTGATGGCG
GCCCACACGGGTCAATCCATCGAAAAAATTGAGAAGGATACGGATCGGGATTACTTTATGTCAGCCCAGGAAGCGTTGGA
ATATGGCCTGATCGATAAGGTAATTGAAGAACGTCCTTAA

Upstream 100 bases:

>100_bases
TCGAAGGACTTGCCGTCCCCCGTACCGGCTCTGTAGTCTTCGTGATTGCTTAAAATCACCCCATTTTTTCCCGTTGTTCA
GATCAAGGTAAACAAAATCC

Downstream 100 bases:

>100_bases
TGTTTGTCTGATTTTTCAACCTTAAATTCGTTGAAGCATTCTTTCTCGCGAAAGGGTGCTTTTTTATGTGGAAAATCTTT
CAAATCTCTATTGTTGAGTA

Product: ATP-dependent Clp protease proteolytic subunit

Products: NA

Alternate protein names: Endopeptidase Clp 2 [H]

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MPIGVPKVPYQMPGQPYSDWINIYDRLYRERIIFLGRGVNDALANQIIAIMLYLDSEDPSKPIYLYINSPGGSVTAGLAI
YDTMKHIKSEVVTICVGLAASMGAFLLSAGTKGKRLALPHSRIMIHQPLGGIQGRRQATDIDIEAKEIIRIKHQLNELMA
AHTGQSIEKIEKDTDRDYFMSAQEALEYGLIDKVIEERP

Sequences:

>Translated_199_residues
MPIGVPKVPYQMPGQPYSDWINIYDRLYRERIIFLGRGVNDALANQIIAIMLYLDSEDPSKPIYLYINSPGGSVTAGLAI
YDTMKHIKSEVVTICVGLAASMGAFLLSAGTKGKRLALPHSRIMIHQPLGGIQGRRQATDIDIEAKEIIRIKHQLNELMA
AHTGQSIEKIEKDTDRDYFMSAQEALEYGLIDKVIEERP
>Mature_198_residues
PIGVPKVPYQMPGQPYSDWINIYDRLYRERIIFLGRGVNDALANQIIAIMLYLDSEDPSKPIYLYINSPGGSVTAGLAIY
DTMKHIKSEVVTICVGLAASMGAFLLSAGTKGKRLALPHSRIMIHQPLGGIQGRRQATDIDIEAKEIIRIKHQLNELMAA
HTGQSIEKIEKDTDRDYFMSAQEALEYGLIDKVIEERP

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

Organism=Homo sapiens, GI5174419, Length=178, Percent_Identity=55.0561797752809, Blast_Score=196, Evalue=1e-50,
Organism=Escherichia coli, GI1786641, Length=178, Percent_Identity=63.4831460674157, Blast_Score=241, Evalue=3e-65,
Organism=Caenorhabditis elegans, GI17538017, Length=173, Percent_Identity=56.6473988439306, Blast_Score=194, Evalue=2e-50,
Organism=Drosophila melanogaster, GI20129427, Length=178, Percent_Identity=51.685393258427, Blast_Score=186, Evalue=7e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907
- InterPro:   IPR018215 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 22228; Mature: 22097

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00381 CLP_PROTEASE_SER ; PS00382 CLP_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIGVPKVPYQMPGQPYSDWINIYDRLYRERIIFLGRGVNDALANQIIAIMLYLDSEDPS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEEECCCCCC
KPIYLYINSPGGSVTAGLAIYDTMKHIKSEVVTICVGLAASMGAFLLSAGTKGKRLALPH
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCC
SRIMIHQPLGGIQGRRQATDIDIEAKEIIRIKHQLNELMAAHTGQSIEKIEKDTDRDYFM
CEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHH
SAQEALEYGLIDKVIEERP
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PIGVPKVPYQMPGQPYSDWINIYDRLYRERIIFLGRGVNDALANQIIAIMLYLDSEDPS
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEEECCCCCC
KPIYLYINSPGGSVTAGLAIYDTMKHIKSEVVTICVGLAASMGAFLLSAGTKGKRLALPH
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCC
SRIMIHQPLGGIQGRRQATDIDIEAKEIIRIKHQLNELMAAHTGQSIEKIEKDTDRDYFM
CEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHH
SAQEALEYGLIDKVIEERP
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA