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The map label for this gene is menF [H]

Identifier: 170077620

GI number: 170077620

Start: 1027828

End: 1029198

Strand: Direct

Name: menF [H]

Synonym: SYNPCC7002_A0999

Alternate gene names: 170077620

Gene position: 1027828-1029198 (Clockwise)

Preceding gene: 170077619

Following gene: 170077621

Centisome position: 34.17

GC content: 53.98

Gene sequence:

>1371_bases
ATGGGAGCTTCCTGCCAACGGCGTCAACTGTCCCCATCAACCTGGCAACAATGGCTCACCCAAAGAACCCCCGCACCATC
TGGGGAAATTGTCAGCGAAATCACTAAAATTCCAGCGGTGGATAGTCTAGTGGTGCTCCGGGCCATTGAACAAATTCTGC
CCAGTCCCCTCAATCACTTCTATTGGGAAAATCGCCAACAGCAACGGGCAATCCTCAATTTTGGCACCCTAAGCGAATTA
GTTCCCCAGGGAGAGGATCGTTTTCGCCAAGCCCAGCAATTTATTACCCATTGGCAACCGAGAATTCAGCGCAATATCAA
CGTTCCGATTCCCTACTTTTCCTGTGGGTTCACTTTTTTTAGTGCCCAAACCCCCGAAGCGCCTTTTCCGGCTGGCTTGG
TCACCATTCCTAGACTGCAACTGGTGCAACACCAACGGGATTATTTTTTAGTGCTCAATGGCGATCGCCAACAGCGCACC
CTCTTACGCCAAATCGCTCAGCAATTGCGCCAGTTTCTCGCGACTCTGCCCCAGGAACTTGTCCCTTCCCTAGGGATTCG
GGGCACTGTCTGCACCGCCTCAACGGGATTTACCCAGGCTGTCCGGCGAGCCCTCCGACTCATTGACCAAGGCAAACTCA
GTAAAATCGTTCTGGCCCATGCCCTCGATGTCACGGCCAATCAAGCCTTTGATGTGGTGCATGCCCTGGATAATCTGCGC
GATCGCCACCCGGACTGTTGTGTTTTTTCCCTCCGTAATCAGCGGGGTGACACATTTATCGGCGCAAGTCCAGAACGGTT
GTTAGCGGTACAACAGGGACAATTGGTGACCGATGCCCTCGCCGGATCTGCCCCCCGGGGGGAATCTTTGCTCACAGATC
AGCGTCTCGCCAAAAGCCTACTCCACAGTGAAAAGGAACAACGGGAACACCAGGCCGTGGCAGATTTTCTACTAGGACAA
CTCCAGAGCCTTGGTCTCGATCCCCAGGCGGCTCCCCGTAAGCTCCTTAAACTTTCTAATATTCAGCACCTCTGGACACC
GATTCATGCAATCCTACCGCCGCAAATTCATCCCCTAGAGGTAGTAGCCCACTTACATCCAACACCAGCAGTGGCCGGTG
TCCCCAGGGCGATCGCCTGTGCGGAAATTCGCCAAGCAGAAACCTTTGACCGTACCCTTTATGCCGCTCCTATCGGTTGG
CTCGATAGTCAGGGCAATAGTGAATTTATCGTGGCGATTCGGTCGGCCTTAATTCGGGGTAACCATGCGCGACTCTACGG
TGGGGCCGGAATTGTCGCCGGTTCCCAGCCGGAACGGGAATATGCCGAAGTCCAGTTAAAATTGACCTCCCTTTTGGAAG
CCCTGACCTGA

Upstream 100 bases:

>100_bases
CGTTGTCCATCGTCCTAGAGGGATCTGAATTGTGGGAAAAACGCTTTGGCGCGATCGCCTAGAGCCGGATCAAAGTCACG
GTTCGGCATTGGGGGAGGGA

Downstream 100 bases:

>100_bases
ACTTTCCCCCAGGAAAAGTTGCTAAGATCGCAGTGTAACGGAAAGTAAAGGCCGCTCCCATGAAGCGCATTGTGATCATC
ACCGGGTTTGAAGCGTTTAA

Product: isochorismate synthase

Products: NA

Alternate protein names: Isochorismate mutase [H]

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MGASCQRRQLSPSTWQQWLTQRTPAPSGEIVSEITKIPAVDSLVVLRAIEQILPSPLNHFYWENRQQQRAILNFGTLSEL
VPQGEDRFRQAQQFITHWQPRIQRNINVPIPYFSCGFTFFSAQTPEAPFPAGLVTIPRLQLVQHQRDYFLVLNGDRQQRT
LLRQIAQQLRQFLATLPQELVPSLGIRGTVCTASTGFTQAVRRALRLIDQGKLSKIVLAHALDVTANQAFDVVHALDNLR
DRHPDCCVFSLRNQRGDTFIGASPERLLAVQQGQLVTDALAGSAPRGESLLTDQRLAKSLLHSEKEQREHQAVADFLLGQ
LQSLGLDPQAAPRKLLKLSNIQHLWTPIHAILPPQIHPLEVVAHLHPTPAVAGVPRAIACAEIRQAETFDRTLYAAPIGW
LDSQGNSEFIVAIRSALIRGNHARLYGGAGIVAGSQPEREYAEVQLKLTSLLEALT

Sequences:

>Translated_456_residues
MGASCQRRQLSPSTWQQWLTQRTPAPSGEIVSEITKIPAVDSLVVLRAIEQILPSPLNHFYWENRQQQRAILNFGTLSEL
VPQGEDRFRQAQQFITHWQPRIQRNINVPIPYFSCGFTFFSAQTPEAPFPAGLVTIPRLQLVQHQRDYFLVLNGDRQQRT
LLRQIAQQLRQFLATLPQELVPSLGIRGTVCTASTGFTQAVRRALRLIDQGKLSKIVLAHALDVTANQAFDVVHALDNLR
DRHPDCCVFSLRNQRGDTFIGASPERLLAVQQGQLVTDALAGSAPRGESLLTDQRLAKSLLHSEKEQREHQAVADFLLGQ
LQSLGLDPQAAPRKLLKLSNIQHLWTPIHAILPPQIHPLEVVAHLHPTPAVAGVPRAIACAEIRQAETFDRTLYAAPIGW
LDSQGNSEFIVAIRSALIRGNHARLYGGAGIVAGSQPEREYAEVQLKLTSLLEALT
>Mature_455_residues
GASCQRRQLSPSTWQQWLTQRTPAPSGEIVSEITKIPAVDSLVVLRAIEQILPSPLNHFYWENRQQQRAILNFGTLSELV
PQGEDRFRQAQQFITHWQPRIQRNINVPIPYFSCGFTFFSAQTPEAPFPAGLVTIPRLQLVQHQRDYFLVLNGDRQQRTL
LRQIAQQLRQFLATLPQELVPSLGIRGTVCTASTGFTQAVRRALRLIDQGKLSKIVLAHALDVTANQAFDVVHALDNLRD
RHPDCCVFSLRNQRGDTFIGASPERLLAVQQGQLVTDALAGSAPRGESLLTDQRLAKSLLHSEKEQREHQAVADFLLGQL
QSLGLDPQAAPRKLLKLSNIQHLWTPIHAILPPQIHPLEVVAHLHPTPAVAGVPRAIACAEIRQAETFDRTLYAAPIGWL
DSQGNSEFIVAIRSALIRGNHARLYGGAGIVAGSQPEREYAEVQLKLTSLLEALT

Specific function: Siderophore biosynthesis; enterobactin biosynthesis. [C]

COG id: COG1169

COG function: function code HQ; Isochorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isochorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786809, Length=263, Percent_Identity=35.7414448669202, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI87082077, Length=448, Percent_Identity=30.3571428571429, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1788114, Length=208, Percent_Identity=26.4423076923077, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787518, Length=451, Percent_Identity=22.1729490022173, Blast_Score=69, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6320935, Length=212, Percent_Identity=28.7735849056604, Blast_Score=80, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR015890
- InterPro:   IPR004561 [H]

Pfam domain/function: PF00425 Chorismate_bind [H]

EC number: =5.4.4.2 [H]

Molecular weight: Translated: 50752; Mature: 50621

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGASCQRRQLSPSTWQQWLTQRTPAPSGEIVSEITKIPAVDSLVVLRAIEQILPSPLNHF
CCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHH
YWENRQQQRAILNFGTLSELVPQGEDRFRQAQQFITHWQPRIQRNINVPIPYFSCGFTFF
HHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCEEE
SAQTPEAPFPAGLVTIPRLQLVQHQRDYFLVLNGDRQQRTLLRQIAQQLRQFLATLPQEL
ECCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCHHHH
VPSLGIRGTVCTASTGFTQAVRRALRLIDQGKLSKIVLAHALDVTANQAFDVVHALDNLR
HHCCCCCCEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRHPDCCVFSLRNQRGDTFIGASPERLLAVQQGQLVTDALAGSAPRGESLLTDQRLAKSL
HCCCCEEEEEECCCCCCEEECCCHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHHHH
LHSEKEQREHQAVADFLLGQLQSLGLDPQAAPRKLLKLSNIQHLWTPIHAILPPQIHPLE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHH
VVAHLHPTPAVAGVPRAIACAEIRQAETFDRTLYAAPIGWLDSQGNSEFIVAIRSALIRG
HHHHCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCC
NHARLYGGAGIVAGSQPEREYAEVQLKLTSLLEALT
CCEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
GASCQRRQLSPSTWQQWLTQRTPAPSGEIVSEITKIPAVDSLVVLRAIEQILPSPLNHF
CCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHH
YWENRQQQRAILNFGTLSELVPQGEDRFRQAQQFITHWQPRIQRNINVPIPYFSCGFTFF
HHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCEEE
SAQTPEAPFPAGLVTIPRLQLVQHQRDYFLVLNGDRQQRTLLRQIAQQLRQFLATLPQEL
ECCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCHHHH
VPSLGIRGTVCTASTGFTQAVRRALRLIDQGKLSKIVLAHALDVTANQAFDVVHALDNLR
HHCCCCCCEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRHPDCCVFSLRNQRGDTFIGASPERLLAVQQGQLVTDALAGSAPRGESLLTDQRLAKSL
HCCCCEEEEEECCCCCCEEECCCHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHHHH
LHSEKEQREHQAVADFLLGQLQSLGLDPQAAPRKLLKLSNIQHLWTPIHAILPPQIHPLE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHH
VVAHLHPTPAVAGVPRAIACAEIRQAETFDRTLYAAPIGWLDSQGNSEFIVAIRSALIRG
HHHHCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCC
NHARLYGGAGIVAGSQPEREYAEVQLKLTSLLEALT
CCEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1629163; 8566759; 9387221; 9384377; 3131310 [H]