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The map label for this gene is relA [H]

Identifier: 170077344

GI number: 170077344

Start: 751864

End: 752406

Strand: Direct

Name: relA [H]

Synonym: SYNPCC7002_A0721

Alternate gene names: 170077344

Gene position: 751864-752406 (Clockwise)

Preceding gene: 170077339

Following gene: 170077345

Centisome position: 25.0

GC content: 39.04

Gene sequence:

>543_bases
ATGAAAATTTGGGATCAAGATAAATATCAAAAAGCATGGAATTTCGCTTCAAATGCACACAACGGTCAGAAATTACCAGG
CAGTGATATTCCTTACATCAATCATCTTGGGCTGGTTGCCATGGAAGCAACAGCAACGGTGGCCCATGAGAGAATTGACA
ATCCAAACATTCTTGTTTTGTGTGCATTATTGCATGATGTCATTGAAGATACTTCTACTACATTTGAGGATGTAAAACGT
GATTTTGGGATTGAAATCGCCGATGGGGTTTTAGCACTGACTAAAAATACAGAACTGCCTTCAAAATTTGAGCAAATGAA
AGACAGTATCAACAGAATTCAATTGCAACCTAAGGAAGTGTGGATGGTTAAATTATGCGATCGCATTACTAACTTACAAC
CACCGCCAATGCATTGGGATAAAGTCAAAATAGCTACATACCAGAGTGAAGCACAGTTTATCTTAGAACAACTCGGTGAG
GCCAGTCCGTTTCTTGCACAGCGATTGATCGTCAAAATATCCGATTACGACCAATATCTATAG

Upstream 100 bases:

>100_bases
TGTTAGTTTAGTCTAAATCGCTTCATAAAATTCTATGGGAAAGTAACAAAAAGAATGTTATGGGAAAAGTATTCGTATAA
TAGTTAAAAAAAGGTAATCA

Downstream 100 bases:

>100_bases
GAAATATGCCTCAATTATTAATTGACGGAAACTTTGAGATTTTTAGCGATTTTTAGCGATCGCCAACCGGGAAGGTTAGC
CTGGAGGAGTCTAGTCGTAA

Product: HD domain-containing protein

Products: NA

Alternate protein names: (p)ppGpp synthase; ATP:GTP 3'-pyrophosphotransferase; ppGpp synthase I [H]

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MKIWDQDKYQKAWNFASNAHNGQKLPGSDIPYINHLGLVAMEATATVAHERIDNPNILVLCALLHDVIEDTSTTFEDVKR
DFGIEIADGVLALTKNTELPSKFEQMKDSINRIQLQPKEVWMVKLCDRITNLQPPPMHWDKVKIATYQSEAQFILEQLGE
ASPFLAQRLIVKISDYDQYL

Sequences:

>Translated_180_residues
MKIWDQDKYQKAWNFASNAHNGQKLPGSDIPYINHLGLVAMEATATVAHERIDNPNILVLCALLHDVIEDTSTTFEDVKR
DFGIEIADGVLALTKNTELPSKFEQMKDSINRIQLQPKEVWMVKLCDRITNLQPPPMHWDKVKIATYQSEAQFILEQLGE
ASPFLAQRLIVKISDYDQYL
>Mature_180_residues
MKIWDQDKYQKAWNFASNAHNGQKLPGSDIPYINHLGLVAMEATATVAHERIDNPNILVLCALLHDVIEDTSTTFEDVKR
DFGIEIADGVLALTKNTELPSKFEQMKDSINRIQLQPKEVWMVKLCDRITNLQPPPMHWDKVKIATYQSEAQFILEQLGE
ASPFLAQRLIVKISDYDQYL

Specific function: In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which i

COG id: COG0317

COG function: function code TK; Guanosine polyphosphate pyrophosphohydrolases/synthetases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HD domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI25143118, Length=142, Percent_Identity=31.6901408450704, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR012675
- InterPro:   IPR003607
- InterPro:   IPR007685
- InterPro:   IPR004811
- InterPro:   IPR004095
- InterPro:   IPR012676 [H]

Pfam domain/function: PF01842 ACT; PF04607 RelA_SpoT; PF02824 TGS [H]

EC number: =2.7.6.5 [H]

Molecular weight: Translated: 20597; Mature: 20597

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIWDQDKYQKAWNFASNAHNGQKLPGSDIPYINHLGLVAMEATATVAHERIDNPNILVL
CCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
CALLHDVIEDTSTTFEDVKRDFGIEIADGVLALTKNTELPSKFEQMKDSINRIQLQPKEV
HHHHHHHHHCCCHHHHHHHHHCCCEECCCEEEEECCCCCHHHHHHHHHHHHHEECCHHHH
WMVKLCDRITNLQPPPMHWDKVKIATYQSEAQFILEQLGEASPFLAQRLIVKISDYDQYL
HHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKIWDQDKYQKAWNFASNAHNGQKLPGSDIPYINHLGLVAMEATATVAHERIDNPNILVL
CCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
CALLHDVIEDTSTTFEDVKRDFGIEIADGVLALTKNTELPSKFEQMKDSINRIQLQPKEV
HHHHHHHHHCCCHHHHHHHHHCCCEECCCEEEEECCCCCHHHHHHHHHHHHHEECCHHHH
WMVKLCDRITNLQPPPMHWDKVKIATYQSEAQFILEQLGEASPFLAQRLIVKISDYDQYL
HHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11418146 [H]