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The map label for this gene is thrS [H]

Identifier: 170077251

GI number: 170077251

Start: 657566

End: 659380

Strand: Reverse

Name: thrS [H]

Synonym: SYNPCC7002_A0628

Alternate gene names: 170077251

Gene position: 659380-657566 (Counterclockwise)

Preceding gene: 170077252

Following gene: 170077250

Centisome position: 21.92

GC content: 51.74

Gene sequence:

>1815_bases
ATGGATCAGGTGAATGGTGAACAACTCGAACCGATGAAACTTCCCAAAACCAGTGAATCAGACACCCTCAAGCGGATTCG
TCACACCACCTCCCACGTCATGGCGATGGCAGTGCAAAAGCTATTTCCCGACGCCCAGGTCACCATTGGTCCTTGGACAG
AGAATGGGTTTTACTACGATTTTGATAAGCCAGAACCCTTCACCGAAGCGGATCTCAAGGCAATCAAAAAAGAGATGGTA
AAAATCGTCAAGAAAAAATTGCCTGTCGTTCGTGAAGAAATTTCCCGCGCCGAAGCCGAAAAACGGATCAAGGAAATTAA
CGAACCCTACAAACTCGAAATCCTCGCAGGAATTCACGACCCCATCACCCTCTACTACCTCGGCGATCAATGGTGGGATC
TTTGTGCTGGCCCCCACGTGGAAAATACCGGTGATATTAACCCCAAGGCGATCGCCCTCGAATCGGTCGCCGGAGCCTAC
TGGCGGGGTGACGAAAATAACCAGCAACTCCAGCGTATTTACGGCACCGCTTGGGAAACCCCCGAACAGCTCAAAGAATA
CCAACGCCGCAAAGAGGAAGCCCTCAAACGCGACCACCGCAAACTCGGCAGAGAACTGGGTTTGTTTATGTTCTCCGATC
AAGTCGGCCCCGGCTTACCCCTCTGGACGCCGAAGGGAACTTTGATCCGTTCCACCCTCGAAAATTTCCTCAAGGCAGAG
CAAACTAAACGCGGCTACCAAGGTGTCGTGACTCCCCACATCGCCCGCGTGGATCTCTTTAAAGTATCCGGTCACTGGCA
GAATTACCGCGAGGATATGTTCCCGATGATGGCGGATGGCGACGCAGAACGGGCGGCGGAACAGGGTTTTGTGATGAAGC
CGATGAACTGCCCCTTTCACATCCAAATTTATAAGGATCAACTGCGTTCCTATCGGGAATTGCCGATCCGTTTGGCAGAA
TTTGGCACGGTTTATCGTTACGAGCAATCCGGTGAATTGGGTGGTTTAACGCGAGTGCGGGGCTTTACCGTGGACGATTC
TCACCTTTTCGTTACGCCAGATCAACTGGAAGCAGAATTCTTTAACGTGGTTGATTTAATTTTGACCGTCTTTAAGAGTT
TGCAACTGAAAAATTTCAAGGCGCGACTAAGCTTCCGTGACCCCAACTCCGATAAATATATTGGCTCCGATGAGGTCTGG
GAAAAGGCGCAAAACGCAATCCGTAAAGCCGTCACCAAGCTCGACATGGACTATTTTGAAGCCGAAGGGGAAGCGGCGTT
CTACGGCCCGAAACTGGACTTTATTTTCCAAGATGTCCTCGAACGGGAATGGCAATTGGGCACGGTACAGGTGGATTACA
ATCTCCCCGAACGGTTTGAATTGGAATATGTTACTGAGCATGGCGATCGCCAACGGCCGATCATGATCCACCGCGCGCCC
TTCGGCTCCTTGGAGCGATTGATCGGCATTCTGATCGAAGAATATGCGGGTGATTTTCCTCTATGGCTCGCCCCCGAACA
GGTCAGAATTCTTCCCGTCAGTGATGAATTTTACGATTACGCCAAGGAACAAGCCGCGAAACTGCAAGCTATGGGGATTC
GGGCCGTGGCTGATGCCTCTGGGGAACGTCTGGGCAAATTGATCCGCAACGCCGAAAAACAGAAAATCCCCGTCATGGCG
ATCGCCGGGGCGAAGGAAGTCGAAGCCAATAGCCTCAGTATCCGCACCCGTGCCTCTGGGGAACTCGGTGCGATTCCGAT
GGAGGAAGTGATTTCCCGCCTCATCGAAGCCAACACGAACCACACCAATTTCTAA

Upstream 100 bases:

>100_bases
TCGGTAAAGGAAAAGTCCCCAGTCCAGCAGGGACAACGGATAATATAGAATGGCGACCTGCTAAACTTTTTGGAGCAATT
TTAAGGAGCATATTTCAACC

Downstream 100 bases:

>100_bases
TATCCGTAGGGGTTTACCACGGTAAACCCTTTTTCGCTTCATTGCGAGGGCTAAATTATGACCCAGGCAAAATCAAAAAT
CCTCTATGATCAAGACTTTT

Product: threonyl-tRNA synthetase

Products: NA

Alternate protein names: Threonine--tRNA ligase; ThrRS [H]

Number of amino acids: Translated: 604; Mature: 604

Protein sequence:

>604_residues
MDQVNGEQLEPMKLPKTSESDTLKRIRHTTSHVMAMAVQKLFPDAQVTIGPWTENGFYYDFDKPEPFTEADLKAIKKEMV
KIVKKKLPVVREEISRAEAEKRIKEINEPYKLEILAGIHDPITLYYLGDQWWDLCAGPHVENTGDINPKAIALESVAGAY
WRGDENNQQLQRIYGTAWETPEQLKEYQRRKEEALKRDHRKLGRELGLFMFSDQVGPGLPLWTPKGTLIRSTLENFLKAE
QTKRGYQGVVTPHIARVDLFKVSGHWQNYREDMFPMMADGDAERAAEQGFVMKPMNCPFHIQIYKDQLRSYRELPIRLAE
FGTVYRYEQSGELGGLTRVRGFTVDDSHLFVTPDQLEAEFFNVVDLILTVFKSLQLKNFKARLSFRDPNSDKYIGSDEVW
EKAQNAIRKAVTKLDMDYFEAEGEAAFYGPKLDFIFQDVLEREWQLGTVQVDYNLPERFELEYVTEHGDRQRPIMIHRAP
FGSLERLIGILIEEYAGDFPLWLAPEQVRILPVSDEFYDYAKEQAAKLQAMGIRAVADASGERLGKLIRNAEKQKIPVMA
IAGAKEVEANSLSIRTRASGELGAIPMEEVISRLIEANTNHTNF

Sequences:

>Translated_604_residues
MDQVNGEQLEPMKLPKTSESDTLKRIRHTTSHVMAMAVQKLFPDAQVTIGPWTENGFYYDFDKPEPFTEADLKAIKKEMV
KIVKKKLPVVREEISRAEAEKRIKEINEPYKLEILAGIHDPITLYYLGDQWWDLCAGPHVENTGDINPKAIALESVAGAY
WRGDENNQQLQRIYGTAWETPEQLKEYQRRKEEALKRDHRKLGRELGLFMFSDQVGPGLPLWTPKGTLIRSTLENFLKAE
QTKRGYQGVVTPHIARVDLFKVSGHWQNYREDMFPMMADGDAERAAEQGFVMKPMNCPFHIQIYKDQLRSYRELPIRLAE
FGTVYRYEQSGELGGLTRVRGFTVDDSHLFVTPDQLEAEFFNVVDLILTVFKSLQLKNFKARLSFRDPNSDKYIGSDEVW
EKAQNAIRKAVTKLDMDYFEAEGEAAFYGPKLDFIFQDVLEREWQLGTVQVDYNLPERFELEYVTEHGDRQRPIMIHRAP
FGSLERLIGILIEEYAGDFPLWLAPEQVRILPVSDEFYDYAKEQAAKLQAMGIRAVADASGERLGKLIRNAEKQKIPVMA
IAGAKEVEANSLSIRTRASGELGAIPMEEVISRLIEANTNHTNF
>Mature_604_residues
MDQVNGEQLEPMKLPKTSESDTLKRIRHTTSHVMAMAVQKLFPDAQVTIGPWTENGFYYDFDKPEPFTEADLKAIKKEMV
KIVKKKLPVVREEISRAEAEKRIKEINEPYKLEILAGIHDPITLYYLGDQWWDLCAGPHVENTGDINPKAIALESVAGAY
WRGDENNQQLQRIYGTAWETPEQLKEYQRRKEEALKRDHRKLGRELGLFMFSDQVGPGLPLWTPKGTLIRSTLENFLKAE
QTKRGYQGVVTPHIARVDLFKVSGHWQNYREDMFPMMADGDAERAAEQGFVMKPMNCPFHIQIYKDQLRSYRELPIRLAE
FGTVYRYEQSGELGGLTRVRGFTVDDSHLFVTPDQLEAEFFNVVDLILTVFKSLQLKNFKARLSFRDPNSDKYIGSDEVW
EKAQNAIRKAVTKLDMDYFEAEGEAAFYGPKLDFIFQDVLEREWQLGTVQVDYNLPERFELEYVTEHGDRQRPIMIHRAP
FGSLERLIGILIEEYAGDFPLWLAPEQVRILPVSDEFYDYAKEQAAKLQAMGIRAVADASGERLGKLIRNAEKQKIPVMA
IAGAKEVEANSLSIRTRASGELGAIPMEEVISRLIEANTNHTNF

Specific function: Thrs Is Also A Translational Repressor Protein, It Controls The Translation Of Its Own Gene By Binding To Its mRNA. [C]

COG id: COG0441

COG function: function code J; Threonyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI38202255, Length=573, Percent_Identity=37.696335078534, Blast_Score=384, Evalue=1e-106,
Organism=Homo sapiens, GI20070344, Length=628, Percent_Identity=35.9872611464968, Blast_Score=376, Evalue=1e-104,
Organism=Homo sapiens, GI38570111, Length=571, Percent_Identity=35.9019264448336, Blast_Score=370, Evalue=1e-102,
Organism=Escherichia coli, GI1788013, Length=603, Percent_Identity=39.6351575456053, Blast_Score=467, Evalue=1e-132,
Organism=Caenorhabditis elegans, GI71984184, Length=586, Percent_Identity=35.6655290102389, Blast_Score=390, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI71984192, Length=586, Percent_Identity=35.6655290102389, Blast_Score=390, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6322112, Length=610, Percent_Identity=36.0655737704918, Blast_Score=380, Evalue=1e-106,
Organism=Saccharomyces cerevisiae, GI6322654, Length=422, Percent_Identity=35.0710900473934, Blast_Score=244, Evalue=3e-65,
Organism=Drosophila melanogaster, GI24583842, Length=571, Percent_Identity=38.7040280210158, Blast_Score=416, Evalue=1e-116,
Organism=Drosophila melanogaster, GI28574141, Length=571, Percent_Identity=38.7040280210158, Blast_Score=416, Evalue=1e-116,
Organism=Drosophila melanogaster, GI24583839, Length=571, Percent_Identity=38.7040280210158, Blast_Score=416, Evalue=1e-116,

Paralogues:

None

Copy number: 700 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR002320
- InterPro:   IPR018163
- InterPro:   IPR012947 [H]

Pfam domain/function: PF03129 HGTP_anticodon; PF00587 tRNA-synt_2b; PF07973 tRNA_SAD [H]

EC number: =6.1.1.3 [H]

Molecular weight: Translated: 69352; Mature: 69352

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00018 EF_HAND_1 ; PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQVNGEQLEPMKLPKTSESDTLKRIRHTTSHVMAMAVQKLFPDAQVTIGPWTENGFYYD
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEE
FDKPEPFTEADLKAIKKEMVKIVKKKLPVVREEISRAEAEKRIKEINEPYKLEILAGIHD
CCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCC
PITLYYLGDQWWDLCAGPHVENTGDINPKAIALESVAGAYWRGDENNQQLQRIYGTAWET
CEEEEEECCHHHHHHCCCCCCCCCCCCCHHEEHHHHCCHHCCCCCCHHHHHHHHCCCCCC
PEQLKEYQRRKEEALKRDHRKLGRELGLFMFSDQVGPGLPLWTPKGTLIRSTLENFLKAE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
QTKRGYQGVVTPHIARVDLFKVSGHWQNYREDMFPMMADGDAERAAEQGFVMKPMNCPFH
HHHCCCCCCCCCCEEEEEEEEECCCHHHHHHHCCCCCCCCCHHHHHHCCCEECCCCCCEE
IQIYKDQLRSYRELPIRLAEFGTVYRYEQSGELGGLTRVRGFTVDDSHLFVTPDQLEAEF
EEEHHHHHHHHHHCCHHHHHCCCEEEECCCCCCCCCCEEEEEEECCCEEEECCHHHHHHH
FNVVDLILTVFKSLQLKNFKARLSFRDPNSDKYIGSDEVWEKAQNAIRKAVTKLDMDYFE
HHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AEGEAAFYGPKLDFIFQDVLEREWQLGTVQVDYNLPERFELEYVTEHGDRQRPIMIHRAP
CCCCEEEECCCHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEEHHCCCCCCCCEEEEECC
FGSLERLIGILIEEYAGDFPLWLAPEQVRILPVSDEFYDYAKEQAAKLQAMGIRAVADAS
CHHHHHHHHHHHHHHCCCCCEEECCCCEEEEECCHHHHHHHHHHHHHHHHHCCHHHHCCC
GERLGKLIRNAEKQKIPVMAIAGAKEVEANSLSIRTRASGELGAIPMEEVISRLIEANTN
HHHHHHHHHCCHHHCCCEEEECCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCC
HTNF
CCCC
>Mature Secondary Structure
MDQVNGEQLEPMKLPKTSESDTLKRIRHTTSHVMAMAVQKLFPDAQVTIGPWTENGFYYD
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEE
FDKPEPFTEADLKAIKKEMVKIVKKKLPVVREEISRAEAEKRIKEINEPYKLEILAGIHD
CCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCC
PITLYYLGDQWWDLCAGPHVENTGDINPKAIALESVAGAYWRGDENNQQLQRIYGTAWET
CEEEEEECCHHHHHHCCCCCCCCCCCCCHHEEHHHHCCHHCCCCCCHHHHHHHHCCCCCC
PEQLKEYQRRKEEALKRDHRKLGRELGLFMFSDQVGPGLPLWTPKGTLIRSTLENFLKAE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
QTKRGYQGVVTPHIARVDLFKVSGHWQNYREDMFPMMADGDAERAAEQGFVMKPMNCPFH
HHHCCCCCCCCCCEEEEEEEEECCCHHHHHHHCCCCCCCCCHHHHHHCCCEECCCCCCEE
IQIYKDQLRSYRELPIRLAEFGTVYRYEQSGELGGLTRVRGFTVDDSHLFVTPDQLEAEF
EEEHHHHHHHHHHCCHHHHHCCCEEEECCCCCCCCCCEEEEEEECCCEEEECCHHHHHHH
FNVVDLILTVFKSLQLKNFKARLSFRDPNSDKYIGSDEVWEKAQNAIRKAVTKLDMDYFE
HHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AEGEAAFYGPKLDFIFQDVLEREWQLGTVQVDYNLPERFELEYVTEHGDRQRPIMIHRAP
CCCCEEEECCCHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEEHHCCCCCCCCEEEEECC
FGSLERLIGILIEEYAGDFPLWLAPEQVRILPVSDEFYDYAKEQAAKLQAMGIRAVADAS
CHHHHHHHHHHHHHHCCCCCEEECCCCEEEEECCHHHHHHHHHHHHHHHHHCCHHHHCCC
GERLGKLIRNAEKQKIPVMAIAGAKEVEANSLSIRTRASGELGAIPMEEVISRLIEANTN
HHHHHHHHHCCHHHCCCEEEECCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCC
HTNF
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]