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The map label for this gene is minD [H]

Identifier: 170077139

GI number: 170077139

Start: 544694

End: 545494

Strand: Direct

Name: minD [H]

Synonym: SYNPCC7002_A0514

Alternate gene names: 170077139

Gene position: 544694-545494 (Clockwise)

Preceding gene: 170077138

Following gene: 170077140

Centisome position: 18.11

GC content: 51.69

Gene sequence:

>801_bases
ATGAGTCGCGTTATCGTTGTGACCTCCGGAAAAGGAGGCGTCGGCAAAAGCACCTGTACCGCCAACCTCGGTTCGGCCTT
GGTCAAGCTCGGCAAAAAAGTGGCCCTGGTCGATGCGGACTTTGGTCTGCGAAACCTGGATTTGCTTTTGGGTTTAGAAA
ATCGCGTTGTCTATACGGCCATTGAAGCGATCGCCGGAGAATGTCGCCTCGAACAAGCCCTTGTGAAGGACAAACGGCAG
AATGGTCTCGTCCTCCTGCCAGCAGCCCAAAACCGGAATAAAGAATCCGTCACTCCCACCCAGATGAAACAGCTCATTAT
GCGGCTGAATAAAGCTTTTGATTATATTTTGGTGGACAGTCCGGCGGGCATCGAGATGGGTTTTCGGAATGCGATCGCCG
CCGCGAGGGAAGCACTGATTGTCACAACCCCCGAAGTGGCTGCTGTGCGTGATGCAGACCGGGTTGTGGGTCTTTTAGAA
GCCTATGGCATTAAACGGACGCGCCTTATTGTGAATCGTCTCAAACCAGAAATGGTCAAGCAAAATGAAATGATGAGCGT
CGAGGATGTCCTCGAAATTCTCGCCATTCCGCTCCTGGGGATTATTCCCGACGATAAACAAGTGATTGTTTCCAGTAACC
GGGGCGAACCGTTGGTGCTAGGAGACAAACAAAATGACCTCCCTGCCACCGCGTTTATGAATATTGCCCGCCGTCTAGAG
GGGGAAAAAGTGCCCCTGTTAAACCTAATGGCCAACCAAGAGGGATTCCTTGCCAAAATTCGCCGGATCTTTGCCAGTTA
A

Upstream 100 bases:

>100_bases
GAAACATCTGATCCCCTCTTACCTGTAATATCGTAGCTAAGCTGCCGCAACCAGTGGCTATGTCGTAAGCTTATTGAATT
ATTTATCCACCCAGAAGTCT

Downstream 100 bases:

>100_bases
CTGCTGTCTCTGATGCGGAATATCGCCCTCATTCCCCTCTATGCTGAAATCTAATTAATGTTTCCCTTTGTAATGAGTCA
TGATCCAGGAATTACTTGAA

Product: septum site-determining protein, MinD

Products: NA

Alternate protein names: Cell division inhibitor minD [H]

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MSRVIVVTSGKGGVGKSTCTANLGSALVKLGKKVALVDADFGLRNLDLLLGLENRVVYTAIEAIAGECRLEQALVKDKRQ
NGLVLLPAAQNRNKESVTPTQMKQLIMRLNKAFDYILVDSPAGIEMGFRNAIAAAREALIVTTPEVAAVRDADRVVGLLE
AYGIKRTRLIVNRLKPEMVKQNEMMSVEDVLEILAIPLLGIIPDDKQVIVSSNRGEPLVLGDKQNDLPATAFMNIARRLE
GEKVPLLNLMANQEGFLAKIRRIFAS

Sequences:

>Translated_266_residues
MSRVIVVTSGKGGVGKSTCTANLGSALVKLGKKVALVDADFGLRNLDLLLGLENRVVYTAIEAIAGECRLEQALVKDKRQ
NGLVLLPAAQNRNKESVTPTQMKQLIMRLNKAFDYILVDSPAGIEMGFRNAIAAAREALIVTTPEVAAVRDADRVVGLLE
AYGIKRTRLIVNRLKPEMVKQNEMMSVEDVLEILAIPLLGIIPDDKQVIVSSNRGEPLVLGDKQNDLPATAFMNIARRLE
GEKVPLLNLMANQEGFLAKIRRIFAS
>Mature_265_residues
SRVIVVTSGKGGVGKSTCTANLGSALVKLGKKVALVDADFGLRNLDLLLGLENRVVYTAIEAIAGECRLEQALVKDKRQN
GLVLLPAAQNRNKESVTPTQMKQLIMRLNKAFDYILVDSPAGIEMGFRNAIAAAREALIVTTPEVAAVRDADRVVGLLEA
YGIKRTRLIVNRLKPEMVKQNEMMSVEDVLEILAIPLLGIIPDDKQVIVSSNRGEPLVLGDKQNDLPATAFMNIARRLEG
EKVPLLNLMANQEGFLAKIRRIFAS

Specific function: ATPase required for the correct placement of the division site. Cell division inhibitors minC and minD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to desta

COG id: COG2894

COG function: function code D; Septum formation inhibitor-activating ATPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the parA family. MinD subfamily [H]

Homologues:

Organism=Homo sapiens, GI6912540, Length=237, Percent_Identity=27.4261603375527, Blast_Score=74, Evalue=9e-14,
Organism=Escherichia coli, GI1787423, Length=274, Percent_Identity=43.0656934306569, Blast_Score=219, Evalue=2e-58,
Organism=Drosophila melanogaster, GI24667611, Length=225, Percent_Identity=27.5555555555556, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR010223 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: NA

Molecular weight: Translated: 28983; Mature: 28851

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRVIVVTSGKGGVGKSTCTANLGSALVKLGKKVALVDADFGLRNLDLLLGLENRVVYTA
CCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEECCCCHHHHH
IEAIAGECRLEQALVKDKRQNGLVLLPAAQNRNKESVTPTQMKQLIMRLNKAFDYILVDS
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEC
PAGIEMGFRNAIAAAREALIVTTPEVAAVRDADRVVGLLEAYGIKRTRLIVNRLKPEMVK
CCCCCHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHH
QNEMMSVEDVLEILAIPLLGIIPDDKQVIVSSNRGEPLVLGDKQNDLPATAFMNIARRLE
HCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHC
GEKVPLLNLMANQEGFLAKIRRIFAS
CCCCCEEHHHCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SRVIVVTSGKGGVGKSTCTANLGSALVKLGKKVALVDADFGLRNLDLLLGLENRVVYTA
CEEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEECCCCHHHHH
IEAIAGECRLEQALVKDKRQNGLVLLPAAQNRNKESVTPTQMKQLIMRLNKAFDYILVDS
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEC
PAGIEMGFRNAIAAAREALIVTTPEVAAVRDADRVVGLLEAYGIKRTRLIVNRLKPEMVK
CCCCCHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHH
QNEMMSVEDVLEILAIPLLGIIPDDKQVIVSSNRGEPLVLGDKQNDLPATAFMNIARRLE
HCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHC
GEKVPLLNLMANQEGFLAKIRRIFAS
CCCCCEEHHHCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]