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The map label for this gene is pheS [H]

Identifier: 170077118

GI number: 170077118

Start: 523297

End: 524304

Strand: Direct

Name: pheS [H]

Synonym: SYNPCC7002_A0493

Alternate gene names: 170077118

Gene position: 523297-524304 (Clockwise)

Preceding gene: 170077116

Following gene: 170077119

Centisome position: 17.4

GC content: 53.67

Gene sequence:

>1008_bases
ATGACCACTTCTACTTTGACCCAAATCGAATCTGATTTGCAAACGCTCCAACAGGAAGCCACCGACGCGATCGCCACGGC
GACAGATCTCGACGCCCTCGAAAAATTGCGGGTCAACTACCTCGGCAAGAAGGGTCAACTGTCCCAAATCCTCCGGGGCA
TGGGCAAACTCTCCGCTGAAGAACGGCCAAAAATCGGGGCGATCGCCAACCAAGTTAAAGAAGTCCTCCAGGGGGCTCTT
GATACCAAGCTTGAAACTCTCCAGAAAGCGAAGATCGAAGCCCAACTCAAGGCCGAAACTCTCGATGTCACCATGCCCGG
TGTGGGGCGTCCCCTGGGGAAAATGCACCCGCTCCAGAGCACCATTGATCGGGTTTTAGATATTTTTGTGGGCCTGGGCT
ACACCGTCGCTGAAGGCCCCCAAATTGAGACAGACTATTACAACTTTGAGGCACTCAATACCCCTGCTGACCACCCAGCG
CGGGATATGCAGGATACATTTTATCTGCCGGGCGATCGCCTATTGCGCACCCATACTTCCTCAGTGCAGATTCGCCACAT
GGAGCAAAACGAACCCCCTTTAAGGATCGTTGCCCCGGGCCGGGTTTACCGTCGCGATACCGTCGATGCGACCCACTCCG
CCGTGTTCCATCAGATTGAACTCCTGGCAATTGATAAAAATTTGAAATTCACCGACCTAAAAGGCACCCTCAAGGAATTT
TTGCGGCAGATGTTCGGCGAAGACCTAGAGGTGACCTTCCGGGCCAGCTACTTCCCCTTCACTGAACCTTCCGCCGAAGT
GGATGTGAAATGGCAGGGTAAATGGCTGGAGGTGATGGGTTGTGGCATGGTGGACCCCAATGTCCTCAAAGCTGTCGGCT
ACGACCCAGAAGTTTATACGGGCTTCGCCGCTGGGCTAGGGGTAGAACGCTTTGCCATGGTTCTACACAAGCTGGACGAT
ATTCGCCGTTTGTATAACAGTGATCTGCGCTTTTTGCGTCAGTTCTAG

Upstream 100 bases:

>100_bases
TGGGTTCCTGGTGAAAAATTGACGTTTTTTTATGATCAAGGACGGTTTAAACTGTTAGGGTCTTCACCATCGAAACAAGT
TTAGTCGCACTCTTTTTGGC

Downstream 100 bases:

>100_bases
GCCGTTTTCGACTAGGGTTTCTACAATAGTGGGGAAAGGCGATCGCCTGGTTGATTGCCAATGTCCGCTTAGTATGACCA
AGAACCCTGCATGAGACAGA

Product: phenylalanyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MTTSTLTQIESDLQTLQQEATDAIATATDLDALEKLRVNYLGKKGQLSQILRGMGKLSAEERPKIGAIANQVKEVLQGAL
DTKLETLQKAKIEAQLKAETLDVTMPGVGRPLGKMHPLQSTIDRVLDIFVGLGYTVAEGPQIETDYYNFEALNTPADHPA
RDMQDTFYLPGDRLLRTHTSSVQIRHMEQNEPPLRIVAPGRVYRRDTVDATHSAVFHQIELLAIDKNLKFTDLKGTLKEF
LRQMFGEDLEVTFRASYFPFTEPSAEVDVKWQGKWLEVMGCGMVDPNVLKAVGYDPEVYTGFAAGLGVERFAMVLHKLDD
IRRLYNSDLRFLRQF

Sequences:

>Translated_335_residues
MTTSTLTQIESDLQTLQQEATDAIATATDLDALEKLRVNYLGKKGQLSQILRGMGKLSAEERPKIGAIANQVKEVLQGAL
DTKLETLQKAKIEAQLKAETLDVTMPGVGRPLGKMHPLQSTIDRVLDIFVGLGYTVAEGPQIETDYYNFEALNTPADHPA
RDMQDTFYLPGDRLLRTHTSSVQIRHMEQNEPPLRIVAPGRVYRRDTVDATHSAVFHQIELLAIDKNLKFTDLKGTLKEF
LRQMFGEDLEVTFRASYFPFTEPSAEVDVKWQGKWLEVMGCGMVDPNVLKAVGYDPEVYTGFAAGLGVERFAMVLHKLDD
IRRLYNSDLRFLRQF
>Mature_334_residues
TTSTLTQIESDLQTLQQEATDAIATATDLDALEKLRVNYLGKKGQLSQILRGMGKLSAEERPKIGAIANQVKEVLQGALD
TKLETLQKAKIEAQLKAETLDVTMPGVGRPLGKMHPLQSTIDRVLDIFVGLGYTVAEGPQIETDYYNFEALNTPADHPAR
DMQDTFYLPGDRLLRTHTSSVQIRHMEQNEPPLRIVAPGRVYRRDTVDATHSAVFHQIELLAIDKNLKFTDLKGTLKEFL
RQMFGEDLEVTFRASYFPFTEPSAEVDVKWQGKWLEVMGCGMVDPNVLKAVGYDPEVYTGFAAGLGVERFAMVLHKLDDI
RRLYNSDLRFLRQF

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI5729820, Length=342, Percent_Identity=32.1637426900585, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI4758340, Length=261, Percent_Identity=34.8659003831418, Blast_Score=128, Evalue=7e-30,
Organism=Escherichia coli, GI1788007, Length=326, Percent_Identity=54.601226993865, Blast_Score=365, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI32566635, Length=244, Percent_Identity=34.8360655737705, Blast_Score=143, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17508957, Length=269, Percent_Identity=31.2267657992565, Blast_Score=131, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI32563657, Length=269, Percent_Identity=31.5985130111524, Blast_Score=131, Evalue=6e-31,
Organism=Saccharomyces cerevisiae, GI6321087, Length=294, Percent_Identity=31.6326530612245, Blast_Score=136, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6325304, Length=89, Percent_Identity=48.314606741573, Blast_Score=100, Evalue=4e-22,
Organism=Drosophila melanogaster, GI17137424, Length=287, Percent_Identity=29.9651567944251, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI18858079, Length=296, Percent_Identity=31.7567567567568, Blast_Score=123, Evalue=2e-28,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR004188
- InterPro:   IPR022911
- InterPro:   IPR002319
- InterPro:   IPR010978 [H]

Pfam domain/function: PF02912 Phe_tRNA-synt_N; PF01409 tRNA-synt_2d [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 37691; Mature: 37559

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSTLTQIESDLQTLQQEATDAIATATDLDALEKLRVNYLGKKGQLSQILRGMGKLSAE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCC
ERPKIGAIANQVKEVLQGALDTKLETLQKAKIEAQLKAETLDVTMPGVGRPLGKMHPLQS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHCCHHHH
TIDRVLDIFVGLGYTVAEGPQIETDYYNFEALNTPADHPARDMQDTFYLPGDRLLRTHTS
HHHHHHHHHHCCCCEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCEECCCHHHHHHCCC
SVQIRHMEQNEPPLRIVAPGRVYRRDTVDATHSAVFHQIELLAIDKNLKFTDLKGTLKEF
CEEEEEECCCCCCEEEECCCCEEECCCCHHHHHHHHHHEEEEEECCCCCEECHHHHHHHH
LRQMFGEDLEVTFRASYFPFTEPSAEVDVKWQGKWLEVMGCGMVDPNVLKAVGYDPEVYT
HHHHCCCCEEEEEEECCCCCCCCCCCEEEEECCCEEEEEECCCCCHHHHHHCCCCCHHHH
GFAAGLGVERFAMVLHKLDDIRRLYNSDLRFLRQF
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTSTLTQIESDLQTLQQEATDAIATATDLDALEKLRVNYLGKKGQLSQILRGMGKLSAE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCC
ERPKIGAIANQVKEVLQGALDTKLETLQKAKIEAQLKAETLDVTMPGVGRPLGKMHPLQS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHCCHHHH
TIDRVLDIFVGLGYTVAEGPQIETDYYNFEALNTPADHPARDMQDTFYLPGDRLLRTHTS
HHHHHHHHHHCCCCEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCEECCCHHHHHHCCC
SVQIRHMEQNEPPLRIVAPGRVYRRDTVDATHSAVFHQIELLAIDKNLKFTDLKGTLKEF
CEEEEEECCCCCCEEEECCCCEEECCCCHHHHHHHHHHEEEEEECCCCCEECHHHHHHHH
LRQMFGEDLEVTFRASYFPFTEPSAEVDVKWQGKWLEVMGCGMVDPNVLKAVGYDPEVYT
HHHHCCCCEEEEEEECCCCCCCCCCCEEEEECCCEEEEEECCCCCHHHHHHCCCCCHHHH
GFAAGLGVERFAMVLHKLDDIRRLYNSDLRFLRQF
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]