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The map label for this gene is groEL-II [H]

Identifier: 170076779

GI number: 170076779

Start: 148056

End: 149723

Strand: Direct

Name: groEL-II [H]

Synonym: SYNPCC7002_A0147

Alternate gene names: 170076779

Gene position: 148056-149723 (Clockwise)

Preceding gene: 170076778

Following gene: 170076784

Centisome position: 4.92

GC content: 55.34

Gene sequence:

>1668_bases
ATGGCTAAGATTGTCTCTTTCAAGGATGACTCTAGACGCTCCCTCGAAGCAGGGATTAATGCCCTTGCCGATGCGGTAAA
AATCACCCTCGGCCCCAAGGGTCGGAATGTACTCCTCGAAAAGCAGTATGGTGCGCCCCAAATTGTGAATGATGGGATCA
CCGTTGCAAAGGATATTGAACTTAGTGATCCGCTCCAAAATACGGGGGCGCGGTTAATCCGGGAAGTGGCAGCGAAAACC
AATGACAGTGCTGGGGATGGCACGACCACTGCTACCGTTATGGCCCAAGCGTTGATCCGCGAAGGTTTGAAAAATGTGAC
GGCTGGGGCAAATCCCGTGGCCCTGCGCCGGGGTATTGATGCGGCAGTGAAGTTCCTCGTGAAGGAAGTTGCCGCGATCG
CCAAGCCCGTTGAAGGAGAGGCGATCGCCCAGGTGGCCGCTGTGTCTGCTGGGAATGACGAAGAAGTAGGCCGGATGATC
TCCGAAGCCATGGCCAAAGTCACCAAAGATGGCGTGATCACCGTTGAAGAGTCCAAGTCCCTCGCCACCGAACTGGATGT
AGTCGAAGGAATGCAACTGGATCGCGGTTATATCTCCCCCTATTTCGTCACCGACCAGGAACGGCAAATCGTTGAATTTG
AAAATCCCTACATCCTGATCACCGACAAGAAAATTTCGGCGATCGCCGACCTCGTGCCCGCCCTCGAACAGGTAGCCCGT
TCTGGTCGTCCTTTGCTGATTGTTGCCGAAGACATTGAAGGGGAAGCCCTGGCGACCCTCGTTGTGAACAAAGCCCGTGG
TGTCCTCAATGCCGCCGCGATCAAGGCTCCCAGTTTTGGCGATCGCCGTAAGCAAATGCTCCAGGACATCGCTGTCCTCA
CCGGCGGTCGGGTCATTTCCGAAGAAGTGGGCCTCAGCCTCGAAGCCATTGACCTTGATATGCTCGGTAACGCCGAAAAA
ATCACCATCAGTAAGGAAGAAACTACCATCGTTTCCGGCGGCGGTAGCAAAGCTGACATTGACGCCCGCGTTAGCCAAAT
CCGTAAGCAACTGGCTGAAACCGACTCCGAATATGACATGGAGAAACTCCAGGAGCGGATCGCCAAGCTTGCTGGTGGTG
TCGCTGTGATCAAAGTTGGTGCAGCCACCGAAACTGAACTCAAAGACCGCAAGCTCCGCATCGAAGATGCCCTCAATGCC
ACCAAAGCCGCTGTCGATGAAGGCATTGTTCCTGGTGGTGGCACGACCCTAATTCACCTCGCTGAAAAGGTCGCTGAAGT
AAAGGCAAGCCTCAGTAGCGACGAAGAGAAGCTCGGTGTCGATATCGTTTCCCGCGCCCTAGAAGCGCCCCTCCGCCAAT
TGGCTGATAACGCGGGTGCCGAAGGTTCTGTGGTTGTAGAACGGGTTCGTACCAGTGACTTCAACGTTGGCTACAACGCG
GCCACTGGCGAATATGTCGATATGATTGCCGCTGGCATCATTGACCCGGCGAAGGTTGTCCGTTCTGTTCTGCAAAATGC
AGCCTCCATCGCTGGAATGGTGATCACAACCGAAGCCCTCGTCGTTGAGAAGCCCGAACCCGAAGCGCCCGCCCCTGACA
TGGGTGGTGGTATGCCCGGTATGGGTGGCATGGGCGGCATGGGAATGCCTGGCATGGGAATGATGTAA

Upstream 100 bases:

>100_bases
TTTTGGCCCGTTTGCATCGCCGAAACCAGAAAACATTAGCAGTCGCCCCCTAGGAGTGCTAAATTTGCTAGTGACGTAAA
ACTTTATAACGCAAACTCCT

Downstream 100 bases:

>100_bases
TTTTTCCTGAACCCTTTTAAAGATTCATTATCTGCATTGGGCACCCTCCGGGGTGCTTTTTTTGTTTTCTGGGCGCAAAA
TCTTGGGTTAAGTTAGCCCA

Product: chaperonin GroEL-II (Cpn 60)

Products: NA

Alternate protein names: GroEL protein 1; Protein Cpn60 1 [H]

Number of amino acids: Translated: 555; Mature: 554

Protein sequence:

>555_residues
MAKIVSFKDDSRRSLEAGINALADAVKITLGPKGRNVLLEKQYGAPQIVNDGITVAKDIELSDPLQNTGARLIREVAAKT
NDSAGDGTTTATVMAQALIREGLKNVTAGANPVALRRGIDAAVKFLVKEVAAIAKPVEGEAIAQVAAVSAGNDEEVGRMI
SEAMAKVTKDGVITVEESKSLATELDVVEGMQLDRGYISPYFVTDQERQIVEFENPYILITDKKISAIADLVPALEQVAR
SGRPLLIVAEDIEGEALATLVVNKARGVLNAAAIKAPSFGDRRKQMLQDIAVLTGGRVISEEVGLSLEAIDLDMLGNAEK
ITISKEETTIVSGGGSKADIDARVSQIRKQLAETDSEYDMEKLQERIAKLAGGVAVIKVGAATETELKDRKLRIEDALNA
TKAAVDEGIVPGGGTTLIHLAEKVAEVKASLSSDEEKLGVDIVSRALEAPLRQLADNAGAEGSVVVERVRTSDFNVGYNA
ATGEYVDMIAAGIIDPAKVVRSVLQNAASIAGMVITTEALVVEKPEPEAPAPDMGGGMPGMGGMGGMGMPGMGMM

Sequences:

>Translated_555_residues
MAKIVSFKDDSRRSLEAGINALADAVKITLGPKGRNVLLEKQYGAPQIVNDGITVAKDIELSDPLQNTGARLIREVAAKT
NDSAGDGTTTATVMAQALIREGLKNVTAGANPVALRRGIDAAVKFLVKEVAAIAKPVEGEAIAQVAAVSAGNDEEVGRMI
SEAMAKVTKDGVITVEESKSLATELDVVEGMQLDRGYISPYFVTDQERQIVEFENPYILITDKKISAIADLVPALEQVAR
SGRPLLIVAEDIEGEALATLVVNKARGVLNAAAIKAPSFGDRRKQMLQDIAVLTGGRVISEEVGLSLEAIDLDMLGNAEK
ITISKEETTIVSGGGSKADIDARVSQIRKQLAETDSEYDMEKLQERIAKLAGGVAVIKVGAATETELKDRKLRIEDALNA
TKAAVDEGIVPGGGTTLIHLAEKVAEVKASLSSDEEKLGVDIVSRALEAPLRQLADNAGAEGSVVVERVRTSDFNVGYNA
ATGEYVDMIAAGIIDPAKVVRSVLQNAASIAGMVITTEALVVEKPEPEAPAPDMGGGMPGMGGMGGMGMPGMGMM
>Mature_554_residues
AKIVSFKDDSRRSLEAGINALADAVKITLGPKGRNVLLEKQYGAPQIVNDGITVAKDIELSDPLQNTGARLIREVAAKTN
DSAGDGTTTATVMAQALIREGLKNVTAGANPVALRRGIDAAVKFLVKEVAAIAKPVEGEAIAQVAAVSAGNDEEVGRMIS
EAMAKVTKDGVITVEESKSLATELDVVEGMQLDRGYISPYFVTDQERQIVEFENPYILITDKKISAIADLVPALEQVARS
GRPLLIVAEDIEGEALATLVVNKARGVLNAAAIKAPSFGDRRKQMLQDIAVLTGGRVISEEVGLSLEAIDLDMLGNAEKI
TISKEETTIVSGGGSKADIDARVSQIRKQLAETDSEYDMEKLQERIAKLAGGVAVIKVGAATETELKDRKLRIEDALNAT
KAAVDEGIVPGGGTTLIHLAEKVAEVKASLSSDEEKLGVDIVSRALEAPLRQLADNAGAEGSVVVERVRTSDFNVGYNAA
TGEYVDMIAAGIIDPAKVVRSVLQNAASIAGMVITTEALVVEKPEPEAPAPDMGGGMPGMGGMGGMGMPGMGMM

Specific function: Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions [H]

COG id: COG0459

COG function: function code O; Chaperonin GroEL (HSP60 family)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chaperonin (HSP60) family [H]

Homologues:

Organism=Homo sapiens, GI41399285, Length=529, Percent_Identity=46.8809073724008, Blast_Score=490, Evalue=1e-138,
Organism=Homo sapiens, GI31542947, Length=529, Percent_Identity=46.8809073724008, Blast_Score=490, Evalue=1e-138,
Organism=Homo sapiens, GI5453607, Length=555, Percent_Identity=21.6216216216216, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI58331173, Length=547, Percent_Identity=22.3034734917733, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1790586, Length=529, Percent_Identity=58.6011342155009, Blast_Score=613, Evalue=1e-176,
Organism=Caenorhabditis elegans, GI17555558, Length=532, Percent_Identity=46.6165413533835, Blast_Score=480, Evalue=1e-136,
Organism=Caenorhabditis elegans, GI193210679, Length=213, Percent_Identity=43.1924882629108, Blast_Score=181, Evalue=9e-46,
Organism=Caenorhabditis elegans, GI17564182, Length=561, Percent_Identity=21.5686274509804, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI25144674, Length=175, Percent_Identity=30.8571428571429, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323288, Length=526, Percent_Identity=50.3802281368821, Blast_Score=511, Evalue=1e-145,
Organism=Saccharomyces cerevisiae, GI6322350, Length=563, Percent_Identity=22.202486678508, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322524, Length=134, Percent_Identity=32.8358208955224, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24641193, Length=529, Percent_Identity=48.2041587901701, Blast_Score=502, Evalue=1e-142,
Organism=Drosophila melanogaster, GI24641191, Length=529, Percent_Identity=48.2041587901701, Blast_Score=502, Evalue=1e-142,
Organism=Drosophila melanogaster, GI45550936, Length=529, Percent_Identity=46.3137996219282, Blast_Score=485, Evalue=1e-137,
Organism=Drosophila melanogaster, GI45550132, Length=529, Percent_Identity=46.3137996219282, Blast_Score=485, Evalue=1e-137,
Organism=Drosophila melanogaster, GI45550935, Length=529, Percent_Identity=46.3137996219282, Blast_Score=485, Evalue=1e-137,
Organism=Drosophila melanogaster, GI17864606, Length=553, Percent_Identity=41.7721518987342, Blast_Score=421, Evalue=1e-118,
Organism=Drosophila melanogaster, GI24584129, Length=550, Percent_Identity=34.3636363636364, Blast_Score=298, Evalue=1e-80,
Organism=Drosophila melanogaster, GI19921262, Length=550, Percent_Identity=34.3636363636364, Blast_Score=298, Evalue=1e-80,
Organism=Drosophila melanogaster, GI28571140, Length=575, Percent_Identity=23.304347826087, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI18858175, Length=575, Percent_Identity=23.304347826087, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: 2180 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 480 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 15012 Molecules/Cell In: Growth Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018370
- InterPro:   IPR001844
- InterPro:   IPR002423 [H]

Pfam domain/function: PF00118 Cpn60_TCP1 [H]

EC number: NA

Molecular weight: Translated: 58176; Mature: 58045

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS00296 CHAPERONINS_CPN60

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKIVSFKDDSRRSLEAGINALADAVKITLGPKGRNVLLEKQYGAPQIVNDGITVAKDIE
CCCEECCCCCHHHHHHHHHHHHHHHHEEEECCCCCCEEEEECCCCCCEECCCCEEEECCC
LSDPLQNTGARLIREVAAKTNDSAGDGTTTATVMAQALIREGLKNVTAGANPVALRRGID
CCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
AAVKFLVKEVAAIAKPVEGEAIAQVAAVSAGNDEEVGRMISEAMAKVTKDGVITVEESKS
HHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEECCHH
LATELDVVEGMQLDRGYISPYFVTDQERQIVEFENPYILITDKKISAIADLVPALEQVAR
HHHHHHHHHCCCCCCCCCCCEEECCCCCCEEEECCCEEEEECCHHHHHHHHHHHHHHHHH
SGRPLLIVAEDIEGEALATLVVNKARGVLNAAAIKAPSFGDRRKQMLQDIAVLTGGRVIS
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEH
EEVGLSLEAIDLDMLGNAEKITISKEETTIVSGGGSKADIDARVSQIRKQLAETDSEYDM
HHHCCEEEEEEHHHCCCCCEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCH
EKLQERIAKLAGGVAVIKVGAATETELKDRKLRIEDALNATKAAVDEGIVPGGGTTLIHL
HHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
AEKVAEVKASLSSDEEKLGVDIVSRALEAPLRQLADNAGAEGSVVVERVRTSDFNVGYNA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCC
ATGEYVDMIAAGIIDPAKVVRSVLQNAASIAGMVITTEALVVEKPEPEAPAPDMGGGMPG
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCCCCCCC
MGGMGGMGMPGMGMM
CCCCCCCCCCCCCCC
>Mature Secondary Structure 
AKIVSFKDDSRRSLEAGINALADAVKITLGPKGRNVLLEKQYGAPQIVNDGITVAKDIE
CCEECCCCCHHHHHHHHHHHHHHHHEEEECCCCCCEEEEECCCCCCEECCCCEEEECCC
LSDPLQNTGARLIREVAAKTNDSAGDGTTTATVMAQALIREGLKNVTAGANPVALRRGID
CCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
AAVKFLVKEVAAIAKPVEGEAIAQVAAVSAGNDEEVGRMISEAMAKVTKDGVITVEESKS
HHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEECCHH
LATELDVVEGMQLDRGYISPYFVTDQERQIVEFENPYILITDKKISAIADLVPALEQVAR
HHHHHHHHHCCCCCCCCCCCEEECCCCCCEEEECCCEEEEECCHHHHHHHHHHHHHHHHH
SGRPLLIVAEDIEGEALATLVVNKARGVLNAAAIKAPSFGDRRKQMLQDIAVLTGGRVIS
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEH
EEVGLSLEAIDLDMLGNAEKITISKEETTIVSGGGSKADIDARVSQIRKQLAETDSEYDM
HHHCCEEEEEEHHHCCCCCEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCH
EKLQERIAKLAGGVAVIKVGAATETELKDRKLRIEDALNATKAAVDEGIVPGGGTTLIHL
HHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
AEKVAEVKASLSSDEEKLGVDIVSRALEAPLRQLADNAGAEGSVVVERVRTSDFNVGYNA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCC
ATGEYVDMIAAGIIDPAKVVRSVLQNAASIAGMVITTEALVVEKPEPEAPAPDMGGGMPG
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCCCCCCC
MGGMGGMGMPGMGMM
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA