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The map label for this gene is mutT [H]

Identifier: 170076695

GI number: 170076695

Start: 65831

End: 66229

Strand: Direct

Name: mutT [H]

Synonym: SYNPCC7002_A0060

Alternate gene names: 170076695

Gene position: 65831-66229 (Clockwise)

Preceding gene: 170076684

Following gene: 170076697

Centisome position: 2.19

GC content: 48.87

Gene sequence:

>399_bases
ATGTCGTCTTTGCCCCATAAGCAGATCGGTGTCGCCGTTATTCGCGATCGCCAAGGAAAAATTTTAATTGATCGCCGTTT
AGACCAAGGGGAAATGGCGGGCCTGTGGGAGTTTCCTGGGGGGAAGATCGAACCAGGGGAAACAGTAGAAGCCTGTATTG
CGCGAGAAATCCAAGAAGAAATTAATCTCCAGGTAGAGGTGGGCGATCGCCTTATGCTAATTGAACATGATTACCCGAAA
TTCAAAGTTTCACTCCATGTGCATTGGTGCAGTGTCCTGGCCGGAGAGGCCAAACCCCTTGAATGTGCAGAGATTTTGTG
GGTCAATCCCGGCGAATTGGGGCAATACCAGTTTCCAGAAGCCAATCAAGCGATCATCGAGGCAATTCAAGAAAGCTAA

Upstream 100 bases:

>100_bases
AAATGGTTTATTTCAACAAAAACCTCAATTGATCTGGGCAAATGCGGCGGGAGCCATCTCCTATAATGATCGGGTTTATC
TTGTGTGCGGAGTTAAAAAA

Downstream 100 bases:

>100_bases
ATGGAACCCTAAATCTGGGCCAATCGTCTAAGAATTTTAGTTTGGGTGTGAGGACAATAGAAGGGCGTCGGGGGATCGTA
ACTCAGGCCAGATCTCCGGG

Product: mutator MutT protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 132; Mature: 131

Protein sequence:

>132_residues
MSSLPHKQIGVAVIRDRQGKILIDRRLDQGEMAGLWEFPGGKIEPGETVEACIAREIQEEINLQVEVGDRLMLIEHDYPK
FKVSLHVHWCSVLAGEAKPLECAEILWVNPGELGQYQFPEANQAIIEAIQES

Sequences:

>Translated_132_residues
MSSLPHKQIGVAVIRDRQGKILIDRRLDQGEMAGLWEFPGGKIEPGETVEACIAREIQEEINLQVEVGDRLMLIEHDYPK
FKVSLHVHWCSVLAGEAKPLECAEILWVNPGELGQYQFPEANQAIIEAIQES
>Mature_131_residues
SSLPHKQIGVAVIRDRQGKILIDRRLDQGEMAGLWEFPGGKIEPGETVEACIAREIQEEINLQVEVGDRLMLIEHDYPKF
KVSLHVHWCSVLAGEAKPLECAEILWVNPGELGQYQFPEANQAIIEAIQES

Specific function: Specific for pyrimidine substrates. Acts on 5-methyl- dCTP, CTP and dCTP in decreasing order [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1788056, Length=119, Percent_Identity=33.6134453781513, Blast_Score=73, Evalue=8e-15,
Organism=Escherichia coli, GI1786288, Length=123, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.2.2.-

Molecular weight: Translated: 14844; Mature: 14713

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLPHKQIGVAVIRDRQGKILIDRRLDQGEMAGLWEFPGGKIEPGETVEACIAREIQEE
CCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHH
INLQVEVGDRLMLIEHDYPKFKVSLHVHWCSVLAGEAKPLECAEILWVNPGELGQYQFPE
CCEEEEECCEEEEEECCCCEEEEEEEEEEEEEECCCCCCCCEEEEEEECCCCCCCEECCC
ANQAIIEAIQES
CCHHHHHHHHCC
>Mature Secondary Structure 
SSLPHKQIGVAVIRDRQGKILIDRRLDQGEMAGLWEFPGGKIEPGETVEACIAREIQEE
CCCCCCCCCEEEEECCCCCEEEEECCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHH
INLQVEVGDRLMLIEHDYPKFKVSLHVHWCSVLAGEAKPLECAEILWVNPGELGQYQFPE
CCEEEEECCEEEEEECCCCEEEEEEEEEEEEEECCCCCCCCEEEEEEECCCCCCCEECCC
ANQAIIEAIQES
CCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 11053429 [H]