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The map label for this gene is sugE [H]

Identifier: 170026031

GI number: 170026031

Start: 4207672

End: 4208133

Strand: Reverse

Name: sugE [H]

Synonym: YPK_3817

Alternate gene names: 170026031

Gene position: 4208133-4207672 (Counterclockwise)

Preceding gene: 170026032

Following gene: 170026026

Centisome position: 89.74

GC content: 51.52

Gene sequence:

>462_bases
ATGGCGGTTTTCTGCTATCTGGGGCTAGCAATATTGCCGCTAATTATTGAGCATGATAATGTATCGCGCTTATCTCTCTG
CTGGCTGGGACGACCCAGTTACGCATCTGTTTTTCGGGGACGGCCCCGCCTGAGCGAGGTGGTTACCATGGCTTGGATTA
TTCTGGTTATTGCAGGTTTATTAGAGGTTATTTGGGCTATTGGCCTGAAGTATTCTCATGGTTTTTCGCGGCTGACGCCG
AGCATTATTACCCTCGTCGCAATGGCTGCCAGTGTTTTTCTATTGGCCTATGCGATGAAAAGTTTGCCAGCAGGCACGGC
TTACGCGGTCTGGACCGGCATTGGTGCGGTAGGTACGGCCATTTTAGGCATTGTGCTACTGGGGGAATCGGCCAGTCTGG
CGCGGATACTAAGCTTGGGGCTGATTCTGGCAGGGATTATCGGCTTGAAGTTGGCGTCATAA

Upstream 100 bases:

>100_bases
AGCCGTGATAGCTAGGTTTGTAATAGCCAGTTTGTCATGGCGAGGTTCGTCAGAACTACGTCGTAATCAATCGCGCTAAG
AACGAAAGGAAACCGCTTAA

Downstream 100 bases:

>100_bases
CGCTTGAGTTATAACGTTATGTGCCATAAGGGGGCTGCGCCCTTCGCCGGTTGGCCTACGGAGGTCAAATGAGTCGTAAA
ATTTTGGCAACCGAACTGAG

Product: small multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 152

Protein sequence:

>153_residues
MAVFCYLGLAILPLIIEHDNVSRLSLCWLGRPSYASVFRGRPRLSEVVTMAWIILVIAGLLEVIWAIGLKYSHGFSRLTP
SIITLVAMAASVFLLAYAMKSLPAGTAYAVWTGIGAVGTAILGIVLLGESASLARILSLGLILAGIIGLKLAS

Sequences:

>Translated_153_residues
MAVFCYLGLAILPLIIEHDNVSRLSLCWLGRPSYASVFRGRPRLSEVVTMAWIILVIAGLLEVIWAIGLKYSHGFSRLTP
SIITLVAMAASVFLLAYAMKSLPAGTAYAVWTGIGAVGTAILGIVLLGESASLARILSLGLILAGIIGLKLAS
>Mature_152_residues
AVFCYLGLAILPLIIEHDNVSRLSLCWLGRPSYASVFRGRPRLSEVVTMAWIILVIAGLLEVIWAIGLKYSHGFSRLTPS
IITLVAMAASVFLLAYAMKSLPAGTAYAVWTGIGAVGTAILGIVLLGESASLARILSLGLILAGIIGLKLAS

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=104, Percent_Identity=75.9615384615385, Blast_Score=149, Evalue=6e-38,
Organism=Escherichia coli, GI1786755, Length=94, Percent_Identity=39.3617021276596, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 16154; Mature: 16023

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVFCYLGLAILPLIIEHDNVSRLSLCWLGRPSYASVFRGRPRLSEVVTMAWIILVIAGL
CHHHHHHHHHHHHHHHCCCCCCHHHEEECCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHH
LEVIWAIGLKYSHGFSRLTPSIITLVAMAASVFLLAYAMKSLPAGTAYAVWTGIGAVGTA
HHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ILGIVLLGESASLARILSLGLILAGIIGLKLAS
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AVFCYLGLAILPLIIEHDNVSRLSLCWLGRPSYASVFRGRPRLSEVVTMAWIILVIAGL
HHHHHHHHHHHHHHHCCCCCCHHHEEECCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHH
LEVIWAIGLKYSHGFSRLTPSIITLVAMAASVFLLAYAMKSLPAGTAYAVWTGIGAVGTA
HHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ILGIVLLGESASLARILSLGLILAGIIGLKLAS
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]