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The map label for this gene is nlpI [H]

Identifier: 170025940

GI number: 170025940

Start: 4115248

End: 4116132

Strand: Reverse

Name: nlpI [H]

Synonym: YPK_3725

Alternate gene names: 170025940

Gene position: 4116132-4115248 (Counterclockwise)

Preceding gene: 170025941

Following gene: 170025939

Centisome position: 87.77

GC content: 47.57

Gene sequence:

>885_bases
ATGAAGCCTTTCTTGCGCTGGTGTTACGTTGCGACAGCACTCATGCTGGCAGGATGCAGCAACCATGATTGGCGTAAAGA
CGAGGTTTTGGCAATCCCGTTGCAACCAACGTTACAGCAGGAAGTGATTCTGGCACGCATGGAACAAATCCTTGCAAGTC
GGGCACTTACGGATGATGAGCGCGCGCAGCTTTTATATGAGCGCGGAGTGCTGTATGATAGCCTCGGGCTACGGGCACTA
GCGCGAAATGATTTTTCGCAAGCGTTAGCTATTCGTCCTGATATGCCAGAGGTTTTTAACTATCTTGGCATATATTTAAC
GCAGGCAGGCAATTTTGATGCTGCCTATGAAGCGTTTGATTCTGTACTAGAGCTTGATCCAACTTACAATTACGCGCGTT
TAAACCGGGGTATCGCCTTGTATTATGGCGGTCGATTCCCGTTGGCGCAGGATGATCTGCAGGCGTTTTATCAAGACGAT
CCAAATGATCCCTTCCGTTCATTATGGCTGTATCTGGTGGAAAGAGAAATCGATCCTAAAGCAGCTGTAGTAGCGTTACA
ACAACGCTATGAAAAATCGGACAGAGGGCAATGGGGATGGAATATTGTCGAATTCTACCTGGGCAAGATCAGCGAAAAAT
CGCTGATGGAAAGGCTCAAGGCAGATGCAACGGATAACACTTCGCTCGCTGAGCATCTCAGTGAAACTGACTTCTATTTA
GGTAAACATTACCTAAGTCTGGGGGACAAGAACACCGCTTCGGTGCTGTTCAAACTGACGGTAGCTAACAACGTTCATAA
CTTTGTTGAGCACCGCTATGCATTGTTGGAATTGGCACTTTTGGGCCAAGAACAAGACGACCTATCGGAATCGGACCAGC
AATAG

Upstream 100 bases:

>100_bases
TCATCGGTAAGGGGCTGTGTTATCTCAGGGGCGGGATGCTCTTGTGTTAAACAAATGGATGAAAGGATGTTTATCCAATG
TTTGTCTTCGGGAGTAGGAA

Downstream 100 bases:

>100_bases
CTGACGAACAACTATCAGCCTGATATACCTTGGTTTTTACCAAAGTTAATCACCCTAACAGGTGATGGCCTTTTTGTTCG
TTTTATAATCTAATTTGAGC

Product: lipoprotein NlpI

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MKPFLRWCYVATALMLAGCSNHDWRKDEVLAIPLQPTLQQEVILARMEQILASRALTDDERAQLLYERGVLYDSLGLRAL
ARNDFSQALAIRPDMPEVFNYLGIYLTQAGNFDAAYEAFDSVLELDPTYNYARLNRGIALYYGGRFPLAQDDLQAFYQDD
PNDPFRSLWLYLVEREIDPKAAVVALQQRYEKSDRGQWGWNIVEFYLGKISEKSLMERLKADATDNTSLAEHLSETDFYL
GKHYLSLGDKNTASVLFKLTVANNVHNFVEHRYALLELALLGQEQDDLSESDQQ

Sequences:

>Translated_294_residues
MKPFLRWCYVATALMLAGCSNHDWRKDEVLAIPLQPTLQQEVILARMEQILASRALTDDERAQLLYERGVLYDSLGLRAL
ARNDFSQALAIRPDMPEVFNYLGIYLTQAGNFDAAYEAFDSVLELDPTYNYARLNRGIALYYGGRFPLAQDDLQAFYQDD
PNDPFRSLWLYLVEREIDPKAAVVALQQRYEKSDRGQWGWNIVEFYLGKISEKSLMERLKADATDNTSLAEHLSETDFYL
GKHYLSLGDKNTASVLFKLTVANNVHNFVEHRYALLELALLGQEQDDLSESDQQ
>Mature_294_residues
MKPFLRWCYVATALMLAGCSNHDWRKDEVLAIPLQPTLQQEVILARMEQILASRALTDDERAQLLYERGVLYDSLGLRAL
ARNDFSQALAIRPDMPEVFNYLGIYLTQAGNFDAAYEAFDSVLELDPTYNYARLNRGIALYYGGRFPLAQDDLQAFYQDD
PNDPFRSLWLYLVEREIDPKAAVVALQQRYEKSDRGQWGWNIVEFYLGKISEKSLMERLKADATDNTSLAEHLSETDFYL
GKHYLSLGDKNTASVLFKLTVANNVHNFVEHRYALLELALLGQEQDDLSESDQQ

Specific function: May be involved in cell division. Overexpression of nlpI results in the loss of the rod morphology and the formation of single prolate ellipsoids and pairs of prolate ellipsoids joined by partial constrictions [H]

COG id: COG4785

COG function: function code R; Lipoprotein NlpI, contains TPR repeats

Gene ontology:

Cell location: Cell membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 TPR repeats [H]

Homologues:

Organism=Escherichia coli, GI1789554, Length=294, Percent_Identity=87.0748299319728, Blast_Score=528, Evalue=1e-151,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 33741; Mature: 33741

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPFLRWCYVATALMLAGCSNHDWRKDEVLAIPLQPTLQQEVILARMEQILASRALTDDE
CCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHH
RAQLLYERGVLYDSLGLRALARNDFSQALAIRPDMPEVFNYLGIYLTQAGNFDAAYEAFD
HHHHHHHHCCHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHH
SVLELDPTYNYARLNRGIALYYGGRFPLAQDDLQAFYQDDPNDPFRSLWLYLVEREIDPK
HHHHCCCCCCHHHHCCCEEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHH
AAVVALQQRYEKSDRGQWGWNIVEFYLGKISEKSLMERLKADATDNTSLAEHLSETDFYL
HHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
GKHYLSLGDKNTASVLFKLTVANNVHNFVEHRYALLELALLGQEQDDLSESDQQ
HHHHHHCCCCCCHHEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCC
>Mature Secondary Structure
MKPFLRWCYVATALMLAGCSNHDWRKDEVLAIPLQPTLQQEVILARMEQILASRALTDDE
CCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHH
RAQLLYERGVLYDSLGLRALARNDFSQALAIRPDMPEVFNYLGIYLTQAGNFDAAYEAFD
HHHHHHHHCCHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHH
SVLELDPTYNYARLNRGIALYYGGRFPLAQDDLQAFYQDDPNDPFRSLWLYLVEREIDPK
HHHHCCCCCCHHHHCCCEEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHH
AAVVALQQRYEKSDRGQWGWNIVEFYLGKISEKSLMERLKADATDNTSLAEHLSETDFYL
HHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
GKHYLSLGDKNTASVLFKLTVANNVHNFVEHRYALLELALLGQEQDDLSESDQQ
HHHHHHCCCCCCHHEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]