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The map label for this gene is yeiJ [C]

Identifier: 170025843

GI number: 170025843

Start: 4004158

End: 4005429

Strand: Reverse

Name: yeiJ [C]

Synonym: YPK_3628

Alternate gene names: 170025843

Gene position: 4005429-4004158 (Counterclockwise)

Preceding gene: 170025844

Following gene: 170025842

Centisome position: 85.41

GC content: 51.18

Gene sequence:

>1272_bases
ATGCTCATGAGTTTGGTCGGGATGGCAGTACTGATATTAATCGCCGTACTGCTTTCAAGTAATGCCAGGGCGATTAATCT
TCGCACTGTCATCGGTGCATTTATTATCCAAGTGGTGATTGGTGCGCTGGTGCTATATGTACCGGTTGGCCGCCGTATTC
TAGGGGGGATGTCGGAAGGGGTGGCTAACGTTATTGCTTATGGTAATGAGGGGATCTCATTTATTTTTGGCGGATTGGTT
TCCGACAAAATGTTTGAAGTCTTTGGCAGTGGGGGTTTTGTATTCGCCTTACGTGTATTACCGGTAATTGTATTCTTCTC
TTCATTGATTGCGGTGTTGTATTACCTCGGCGTCATGCAAATCGTTATTAAAGTATTGGGCGGTGGTTTACAAAAACTGC
TGGGCACCTCGCGGACGGAGTCTCTTTCTGCCACAGCCAATATTTTCGTTGGGCAGACAGAAGCGCCGTTAGTTGTTCGC
CCCTATATTGCGACCATGACCCAGTCAGAACTGTTTGCGGTCATGTGTGGTGGCCTGGCCTCGGTTGCAGGCTCGGTATT
GGCCGGGTATGCGCAAATGGGCGTACCGTTGGAATATTTGATTGCCGCCTCCTTTATGGCAGCACCGGGCGGGTTACTGT
TCGCCAAATTAATGGTGCCTGAAACCGAGCAAACCCACGATAAAGTTGATGCTATCGCACTGATCGCGGAAGAGGACCGC
CCAGCTAACGTTATTGATGCCGCAGCTTCTGGGGCAGCCTCTGGTATGCAACTGGCGCTGAATGTCGGGGCGATGCTATT
GGCTTTTATCGCATTGATTGCATTGCTTAATGGCATTCTGGGGGGGATTGGCGGCTGGTTCGATTATCCGCAACTCTCGC
TGGAATTGATTCTGGGCTGGGTGTTCTCGCCCATCGCTTATCTGATCGGCGTGCCATGGAGCGAAGCAATGGTGGCGGGC
TCCTTTATCGGCCAAAAGATTATCGTTAACGAGTTCGTGGCCTTTATGAACTTTGGTCAGTATTTGCAGGCGGACGAGTT
AGTGAAAGCGGCGGGTTTACAGGTGCTCTCTGAACACACCAAAGCGATCATCTCTTTTGCCCTGTGTGGGTTCGCTAACT
TGTCTTCGGTAGCTATTCTACTGGGTGGGCTGGGTAGCATGGCACCAAATCGTCGTCATGATATTGCGCGCTTTGGCCTG
AAAGCCGTGGCCGCAGGGACGTTGTCGAATTTGATGAGTGCGACGATCGCCGGCTTCTTCCTGGCACTGTGA

Upstream 100 bases:

>100_bases
TATTTGTGACGGAGATTACTTGATGGCGAGGTGATGACGTTATAATTGCCGACATCATTTCAATGTGACTAATAGCCTTA
TTATTAATAGGAATATCGAC

Downstream 100 bases:

>100_bases
TGTATAAGGTGCCGTTTTGTAGAACGGCACGTTTCCCCTTCATTCGACTTGGTTAGTCGTCTGAGGTGCCGTTTTTGTCA
AACGGCACCGGCTATCAGGC

Product: nucleoside transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MLMSLVGMAVLILIAVLLSSNARAINLRTVIGAFIIQVVIGALVLYVPVGRRILGGMSEGVANVIAYGNEGISFIFGGLV
SDKMFEVFGSGGFVFALRVLPVIVFFSSLIAVLYYLGVMQIVIKVLGGGLQKLLGTSRTESLSATANIFVGQTEAPLVVR
PYIATMTQSELFAVMCGGLASVAGSVLAGYAQMGVPLEYLIAASFMAAPGGLLFAKLMVPETEQTHDKVDAIALIAEEDR
PANVIDAAASGAASGMQLALNVGAMLLAFIALIALLNGILGGIGGWFDYPQLSLELILGWVFSPIAYLIGVPWSEAMVAG
SFIGQKIIVNEFVAFMNFGQYLQADELVKAAGLQVLSEHTKAIISFALCGFANLSSVAILLGGLGSMAPNRRHDIARFGL
KAVAAGTLSNLMSATIAGFFLAL

Sequences:

>Translated_423_residues
MLMSLVGMAVLILIAVLLSSNARAINLRTVIGAFIIQVVIGALVLYVPVGRRILGGMSEGVANVIAYGNEGISFIFGGLV
SDKMFEVFGSGGFVFALRVLPVIVFFSSLIAVLYYLGVMQIVIKVLGGGLQKLLGTSRTESLSATANIFVGQTEAPLVVR
PYIATMTQSELFAVMCGGLASVAGSVLAGYAQMGVPLEYLIAASFMAAPGGLLFAKLMVPETEQTHDKVDAIALIAEEDR
PANVIDAAASGAASGMQLALNVGAMLLAFIALIALLNGILGGIGGWFDYPQLSLELILGWVFSPIAYLIGVPWSEAMVAG
SFIGQKIIVNEFVAFMNFGQYLQADELVKAAGLQVLSEHTKAIISFALCGFANLSSVAILLGGLGSMAPNRRHDIARFGL
KAVAAGTLSNLMSATIAGFFLAL
>Mature_423_residues
MLMSLVGMAVLILIAVLLSSNARAINLRTVIGAFIIQVVIGALVLYVPVGRRILGGMSEGVANVIAYGNEGISFIFGGLV
SDKMFEVFGSGGFVFALRVLPVIVFFSSLIAVLYYLGVMQIVIKVLGGGLQKLLGTSRTESLSATANIFVGQTEAPLVVR
PYIATMTQSELFAVMCGGLASVAGSVLAGYAQMGVPLEYLIAASFMAAPGGLLFAKLMVPETEQTHDKVDAIALIAEEDR
PANVIDAAASGAASGMQLALNVGAMLLAFIALIALLNGILGGIGGWFDYPQLSLELILGWVFSPIAYLIGVPWSEAMVAG
SFIGQKIIVNEFVAFMNFGQYLQADELVKAAGLQVLSEHTKAIISFALCGFANLSSVAILLGGLGSMAPNRRHDIARFGL
KAVAAGTLSNLMSATIAGFFLAL

Specific function: Unknown

COG id: COG1972

COG function: function code F; Nucleoside permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family [H]

Homologues:

Organism=Homo sapiens, GI11545853, Length=424, Percent_Identity=38.6792452830189, Blast_Score=286, Evalue=3e-77,
Organism=Homo sapiens, GI42542381, Length=423, Percent_Identity=39.0070921985816, Blast_Score=280, Evalue=1e-75,
Organism=Homo sapiens, GI227116277, Length=424, Percent_Identity=37.5, Blast_Score=276, Evalue=3e-74,
Organism=Escherichia coli, GI1788485, Length=423, Percent_Identity=49.8817966903073, Blast_Score=390, Evalue=1e-110,
Organism=Escherichia coli, GI1788488, Length=423, Percent_Identity=48.936170212766, Blast_Score=370, Evalue=1e-103,
Organism=Escherichia coli, GI1788737, Length=424, Percent_Identity=31.8396226415094, Blast_Score=188, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI17560276, Length=402, Percent_Identity=31.8407960199005, Blast_Score=216, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI71991794, Length=409, Percent_Identity=30.5623471882641, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI25146537, Length=206, Percent_Identity=31.5533980582524, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI45552517, Length=422, Percent_Identity=38.8625592417062, Blast_Score=286, Evalue=2e-77,
Organism=Drosophila melanogaster, GI19921868, Length=422, Percent_Identity=38.8625592417062, Blast_Score=286, Evalue=2e-77,
Organism=Drosophila melanogaster, GI45552519, Length=422, Percent_Identity=38.8625592417062, Blast_Score=286, Evalue=3e-77,
Organism=Drosophila melanogaster, GI281360430, Length=414, Percent_Identity=37.43961352657, Blast_Score=250, Evalue=2e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008276
- InterPro:   IPR018270
- InterPro:   IPR011642
- InterPro:   IPR011657
- InterPro:   IPR002668 [H]

Pfam domain/function: PF07670 Gate; PF07662 Nucleos_tra2_C; PF01773 Nucleos_tra2_N [H]

EC number: NA

Molecular weight: Translated: 44139; Mature: 44139

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMSLVGMAVLILIAVLLSSNARAINLRTVIGAFIIQVVIGALVLYVPVGRRILGGMSEG
CHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
VANVIAYGNEGISFIFGGLVSDKMFEVFGSGGFVFALRVLPVIVFFSSLIAVLYYLGVMQ
HHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVIKVLGGGLQKLLGTSRTESLSATANIFVGQTEAPLVVRPYIATMTQSELFAVMCGGLA
HHHHHHCCHHHHHHCCCCCCHHHHHHEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHH
SVAGSVLAGYAQMGVPLEYLIAASFMAAPGGLLFAKLMVPETEQTHDKVDAIALIAEEDR
HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHEEEECCCC
PANVIDAAASGAASGMQLALNVGAMLLAFIALIALLNGILGGIGGWFDYPQLSLELILGW
CCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
VFSPIAYLIGVPWSEAMVAGSFIGQKIIVNEFVAFMNFGQYLQADELVKAAGLQVLSEHT
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAIISFALCGFANLSSVAILLGGLGSMAPNRRHDIARFGLKAVAAGTLSNLMSATIAGFF
HHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAL
HCC
>Mature Secondary Structure
MLMSLVGMAVLILIAVLLSSNARAINLRTVIGAFIIQVVIGALVLYVPVGRRILGGMSEG
CHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
VANVIAYGNEGISFIFGGLVSDKMFEVFGSGGFVFALRVLPVIVFFSSLIAVLYYLGVMQ
HHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVIKVLGGGLQKLLGTSRTESLSATANIFVGQTEAPLVVRPYIATMTQSELFAVMCGGLA
HHHHHHCCHHHHHHCCCCCCHHHHHHEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHH
SVAGSVLAGYAQMGVPLEYLIAASFMAAPGGLLFAKLMVPETEQTHDKVDAIALIAEEDR
HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHEEEECCCC
PANVIDAAASGAASGMQLALNVGAMLLAFIALIALLNGILGGIGGWFDYPQLSLELILGW
CCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
VFSPIAYLIGVPWSEAMVAGSFIGQKIIVNEFVAFMNFGQYLQADELVKAAGLQVLSEHT
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAIISFALCGFANLSSVAILLGGLGSMAPNRRHDIARFGLKAVAAGTLSNLMSATIAGFF
HHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAL
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]