| Definition | Yersinia pseudotuberculosis YPIII chromosome, complete genome. |
|---|---|
| Accession | NC_010465 |
| Length | 4,689,441 |
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The map label for this gene is ftsI [H]
Identifier: 170025739
GI number: 170025739
Start: 3871713
End: 3873476
Strand: Reverse
Name: ftsI [H]
Synonym: YPK_3524
Alternate gene names: 170025739
Gene position: 3873476-3871713 (Counterclockwise)
Preceding gene: 170025740
Following gene: 170025738
Centisome position: 82.6
GC content: 52.95
Gene sequence:
>1764_bases ATGAAGACAGCGCGCCCCGGGAAGTTAAAGCGTCAGGAAGAACAAGCCAGCTTTATTAGCTGGCGTTTTGCGTTGCTGTG CGGTTGTATTTTACTGGCATTGGTTGGGCTGATTATGCGTACCGCATACCTGCAAGTGATCAACCCCGATAAGCTGGTGC GCGAGGGGGATATGCGCTCGCTGCGAGTACAAGAGGTGCCGACGGCGCGTGGCATGATAAGCGATCGCTCTGGCCGCCCT TTGGCGGTCAGTGTACCCGTCAATGCGGTTTGGGCCGATCCAAAAGAACTGATTGAACAGGGGGGGATCTCTCTGGATAC CCGCTGGAAAGCCCTGTCGGATGCATTAGAAATCCCTTTAGATCAACTTGCCACGCGCATTAATGCCAATCCAAAAGGCC GCTTTGTCTATCTGGCCCGTCAGGTGAACCCCGCGATTGGCGACTACATCCGCAAGCTGAAATTACCCGGTATCCATCTA CGTCAGGAATCCCGTCGCTACTATCCGGCAGGTCAGGTGATGGCTCACATTATTGGTGTGACCAATATCGATGGGCAAGG GATTGAAGGTGTTGAGAAAAGTTTTGATCGTTGGCTCACCGGCCAACCGGGCGAGCGAACGGTGCGCAAAGACCGTTATG GCCGTGTTATTGAAGATATCTCCTCTGTTGACAGCCAGGCGGCGCATAACCTGGTGCTGAGTGTGGACGAGCGTTTGCAG GCGTTGGTGTACCGCGAGCTCAATAATGCGGTGGCGTTTAACAAAGCAGAATCGGGCACGGCGGTATTAGTCGATGTGAA CACCGGTGAAGTCTTGGCGATGGCGAACAGCCCGTCTTACAACCCGAATAACCTAACCGGTACGCCGAAAGACGCGATGC GTAACCGGGCAATAACCGATATTTTTGAACCCGGCTCGACAGTCAAGCCAATGGTAGTGATGACGGCCTTACAGCATGGT GTTGTGAAAGAGAACAGTGTGCTGAATACCTTGCCGTACTTTGTTAACGGTCACCAGATTAAAGATGTGGCCCGTTACGC TGAGCTATCCGTCACTGGGATCTTACAGAAGTCGAGTAACGTCGGTGTTTCTAAACTGGCGTTAGCGATGCCATCCTCAG CGTTAGTAGATACTTACTCACGGTTTGGGTTTGGGAAAGCGACCAATTTGGGGTTGGTCGGAGAAAGCAGTGGCTTATAT CCTAAAAAACAACGGTGGTCTGACATAGAGAGGGCCACCTTCTCTTTCGGCTACGGGCTAATGGTAACACCGTTACAACT AGCGCGAGTCTATGCAACCATCGGCAGCATGGGGGTCTATCGCCCGCTGTCGATAACCCGAGTTGACCCACCTGTCGCCG GTGAACGCATCTTCCCTGAACCCCTGGTACGCACCGTGGTTCATATGATGGAAAGCGTGGCACTGCCTGGCGGTGGTGGT ACCAAAGCGGCGATCAAAGGTTACCGTATCGCGATTAAAACCGGTACGGCCAAAAAAGTCGGTCCCGATGGCAAGTATAT GGATCGATACCTCGCTTACACCGCTGGCGTTGCGCCCGCGAGTAACCCTCGATTTGCTCTGGTTGTGGTGATCAATGACC CACAGGCAGGGAAATATTACGGTGGTGCGGTTTCTGCACCGGTATTCGGTGCCATCATGGGCGGCGTTTTGCGTACCATG AACATTGAGCCAGATGCATTACCCACCGGTGATAAAAGCGAATTAGTGATTAATACAAAAGAGGGTTCAGGTGGCAGATC GTAA
Upstream 100 bases:
>100_bases TCGATCCATCACAAGAAAACATTGTGATTAAATAATAGGTTGTTTTTTAACCAATACAGGAATCAGTGACCATCATGACT CGCAGTCGCCAAGGTAATAC
Downstream 100 bases:
>100_bases TTTGCGCGACTTATTCGCTCCTTGGGGGCTAGACGTCCCGGAGCGGGCGCTACGGGAAATGACATTAGACAGCCGTATTG CAGCTGCCGGCGATTTATTT
Product: peptidoglycan glycosyltransferase
Products: NA
Alternate protein names: Penicillin-binding protein 3; PBP-3; Peptidoglycan glycosyltransferase 3 [H]
Number of amino acids: Translated: 587; Mature: 587
Protein sequence:
>587_residues MKTARPGKLKRQEEQASFISWRFALLCGCILLALVGLIMRTAYLQVINPDKLVREGDMRSLRVQEVPTARGMISDRSGRP LAVSVPVNAVWADPKELIEQGGISLDTRWKALSDALEIPLDQLATRINANPKGRFVYLARQVNPAIGDYIRKLKLPGIHL RQESRRYYPAGQVMAHIIGVTNIDGQGIEGVEKSFDRWLTGQPGERTVRKDRYGRVIEDISSVDSQAAHNLVLSVDERLQ ALVYRELNNAVAFNKAESGTAVLVDVNTGEVLAMANSPSYNPNNLTGTPKDAMRNRAITDIFEPGSTVKPMVVMTALQHG VVKENSVLNTLPYFVNGHQIKDVARYAELSVTGILQKSSNVGVSKLALAMPSSALVDTYSRFGFGKATNLGLVGESSGLY PKKQRWSDIERATFSFGYGLMVTPLQLARVYATIGSMGVYRPLSITRVDPPVAGERIFPEPLVRTVVHMMESVALPGGGG TKAAIKGYRIAIKTGTAKKVGPDGKYMDRYLAYTAGVAPASNPRFALVVVINDPQAGKYYGGAVSAPVFGAIMGGVLRTM NIEPDALPTGDKSELVINTKEGSGGRS
Sequences:
>Translated_587_residues MKTARPGKLKRQEEQASFISWRFALLCGCILLALVGLIMRTAYLQVINPDKLVREGDMRSLRVQEVPTARGMISDRSGRP LAVSVPVNAVWADPKELIEQGGISLDTRWKALSDALEIPLDQLATRINANPKGRFVYLARQVNPAIGDYIRKLKLPGIHL RQESRRYYPAGQVMAHIIGVTNIDGQGIEGVEKSFDRWLTGQPGERTVRKDRYGRVIEDISSVDSQAAHNLVLSVDERLQ ALVYRELNNAVAFNKAESGTAVLVDVNTGEVLAMANSPSYNPNNLTGTPKDAMRNRAITDIFEPGSTVKPMVVMTALQHG VVKENSVLNTLPYFVNGHQIKDVARYAELSVTGILQKSSNVGVSKLALAMPSSALVDTYSRFGFGKATNLGLVGESSGLY PKKQRWSDIERATFSFGYGLMVTPLQLARVYATIGSMGVYRPLSITRVDPPVAGERIFPEPLVRTVVHMMESVALPGGGG TKAAIKGYRIAIKTGTAKKVGPDGKYMDRYLAYTAGVAPASNPRFALVVVINDPQAGKYYGGAVSAPVFGAIMGGVLRTM NIEPDALPTGDKSELVINTKEGSGGRS >Mature_587_residues MKTARPGKLKRQEEQASFISWRFALLCGCILLALVGLIMRTAYLQVINPDKLVREGDMRSLRVQEVPTARGMISDRSGRP LAVSVPVNAVWADPKELIEQGGISLDTRWKALSDALEIPLDQLATRINANPKGRFVYLARQVNPAIGDYIRKLKLPGIHL RQESRRYYPAGQVMAHIIGVTNIDGQGIEGVEKSFDRWLTGQPGERTVRKDRYGRVIEDISSVDSQAAHNLVLSVDERLQ ALVYRELNNAVAFNKAESGTAVLVDVNTGEVLAMANSPSYNPNNLTGTPKDAMRNRAITDIFEPGSTVKPMVVMTALQHG VVKENSVLNTLPYFVNGHQIKDVARYAELSVTGILQKSSNVGVSKLALAMPSSALVDTYSRFGFGKATNLGLVGESSGLY PKKQRWSDIERATFSFGYGLMVTPLQLARVYATIGSMGVYRPLSITRVDPPVAGERIFPEPLVRTVVHMMESVALPGGGG TKAAIKGYRIAIKTGTAKKVGPDGKYMDRYLAYTAGVAPASNPRFALVVVINDPQAGKYYGGAVSAPVFGAIMGGVLRTM NIEPDALPTGDKSELVINTKEGSGGRS
Specific function: Cell wall formation. Essential for the formation of a septum of the murein sacculus. Synthesis of cross-linked peptidoglycan from the lipid intermediates [H]
COG id: COG0768
COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2
Gene ontology:
Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side. Note=The bulk of the molecule, except for the N-terminal membrane anchor region, protrudes into the periplasmic space, where it acts on murein (By similarity) [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI1786272, Length=584, Percent_Identity=84.7602739726027, Blast_Score=1038, Evalue=0.0, Organism=Escherichia coli, GI1786854, Length=621, Percent_Identity=24.9597423510467, Blast_Score=142, Evalue=6e-35,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR005311 - InterPro: IPR001460 [H]
Pfam domain/function: PF03717 PBP_dimer; PF00905 Transpeptidase [H]
EC number: =2.4.1.129 [H]
Molecular weight: Translated: 63659; Mature: 63659
Theoretical pI: Translated: 10.07; Mature: 10.07
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 2.9 %Met (Translated Protein) 3.2 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 2.9 %Met (Mature Protein) 3.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKTARPGKLKRQEEQASFISWRFALLCGCILLALVGLIMRTAYLQVINPDKLVREGDMRS CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHCCCCCC LRVQEVPTARGMISDRSGRPLAVSVPVNAVWADPKELIEQGGISLDTRWKALSDALEIPL EEEECCCCCCCCCCCCCCCCEEEECCCCEEECCHHHHHHHCCCCCCHHHHHHHHHHHCCH DQLATRINANPKGRFVYLARQVNPAIGDYIRKLKLPGIHLRQESRRYYPAGQVMAHIIGV HHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCEECHHCCCCCCHHHHHHHHHHC TNIDGQGIEGVEKSFDRWLTGQPGERTVRKDRYGRVIEDISSVDSQAAHNLVLSVDERLQ CCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHH ALVYRELNNAVAFNKAESGTAVLVDVNTGEVLAMANSPSYNPNNLTGTPKDAMRNRAITD HHHHHHHHCCEEECCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCHHHHHCCCHHH IFEPGSTVKPMVVMTALQHGVVKENSVLNTLPYFVNGHQIKDVARYAELSVTGILQKSSN HHCCCCCCCHHHHHHHHHHCCCCCCCHHHHCCHHCCCHHHHHHHHHHHHHHEEEEECCCC VGVSKLALAMPSSALVDTYSRFGFGKATNLGLVGESSGLYPKKQRWSDIERATFSFGYGL CCHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCCH MVTPLQLARVYATIGSMGVYRPLSITRVDPPVAGERIFPEPLVRTVVHMMESVALPGGGG HHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC TKAAIKGYRIAIKTGTAKKVGPDGKYMDRYLAYTAGVAPASNPRFALVVVINDPQAGKYY CHHEECEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCC GGAVSAPVFGAIMGGVLRTMNIEPDALPTGDKSELVINTKEGSGGRS CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCC >Mature Secondary Structure MKTARPGKLKRQEEQASFISWRFALLCGCILLALVGLIMRTAYLQVINPDKLVREGDMRS CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHCCCCCC LRVQEVPTARGMISDRSGRPLAVSVPVNAVWADPKELIEQGGISLDTRWKALSDALEIPL EEEECCCCCCCCCCCCCCCCEEEECCCCEEECCHHHHHHHCCCCCCHHHHHHHHHHHCCH DQLATRINANPKGRFVYLARQVNPAIGDYIRKLKLPGIHLRQESRRYYPAGQVMAHIIGV HHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCEECHHCCCCCCHHHHHHHHHHC TNIDGQGIEGVEKSFDRWLTGQPGERTVRKDRYGRVIEDISSVDSQAAHNLVLSVDERLQ CCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHH ALVYRELNNAVAFNKAESGTAVLVDVNTGEVLAMANSPSYNPNNLTGTPKDAMRNRAITD HHHHHHHHCCEEECCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCHHHHHCCCHHH IFEPGSTVKPMVVMTALQHGVVKENSVLNTLPYFVNGHQIKDVARYAELSVTGILQKSSN HHCCCCCCCHHHHHHHHHHCCCCCCCHHHHCCHHCCCHHHHHHHHHHHHHHEEEEECCCC VGVSKLALAMPSSALVDTYSRFGFGKATNLGLVGESSGLYPKKQRWSDIERATFSFGYGL CCHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCCH MVTPLQLARVYATIGSMGVYRPLSITRVDPPVAGERIFPEPLVRTVVHMMESVALPGGGG HHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC TKAAIKGYRIAIKTGTAKKVGPDGKYMDRYLAYTAGVAPASNPRFALVVVINDPQAGKYY CHHEECEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCC GGAVSAPVFGAIMGGVLRTMNIEPDALPTGDKSELVINTKEGSGGRS CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]