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The map label for this gene is lsrR [H]

Identifier: 170025632

GI number: 170025632

Start: 3749742

End: 3750713

Strand: Direct

Name: lsrR [H]

Synonym: YPK_3417

Alternate gene names: 170025632

Gene position: 3749742-3750713 (Clockwise)

Preceding gene: 170025631

Following gene: 170025637

Centisome position: 79.96

GC content: 49.79

Gene sequence:

>972_bases
ATGGAAAAGCAGATGATCCCACAAGACAATGAGTTGTTAACTGAAATTGCTGTTTCGTATTATCAGGATGAAATGACTCA
GGAAGAAATCGCCCATAAATTTGGCATTTCAAGGATCAAAGTCGGTCGCTTGCTGAAACGCGCGAAAACAGAGGGCATCG
TTGAGATTAACGTTCGTTATCATCCGGTATTCAGTACCCGCCTTGAGCAACAGTTAATCGAGCATTTTGGGTTGAAACGG
GCGCTGATAGCCCTTGATTACCAAGATGAGGATGAACAACGCCGCCAGGTCGCCGCGTTGGTTTCAGCCTACTTAGCCAC
AAACTTAAAAGACAACACGGTGTTGGCCGTTGGCCAGGGGCGTAATGTTGCGGCTATCGCAGACCACGTCAGCGTCGTGC
CAGAAAGGCACTGTAAGTTTATCTGTGGCATCGGTGGAACACACCGCCCAGGTGATGCGATTAATGCCGATCACATCAGT
CGCCGCTTAGCCAAAAAATTTGGCGGAACGAGTGAAACCCTGTACGCACCCGCGTATGTGGAAAACCGGGCGCTAAAAGA
AGCCTTTATGCAAAACGGTACCATTAAAGAGACTCTGGATCGCGCCCGTAAGGCTGATATGGCTCTGGTTGGCATCGGTG
ATATGAACGAAAACAGCTATATGGTAGAGCTGGGCTGGTTCACTCCTCAGGAGATCGTCGACGCCAGTCTGCATCAAGGT
GTGACAGGCGAAATTGCGGGATATGATTTTTTTGATGCGCAAGGCCAACCCGCGAATACGGTGATGAATGATCGGGTTAT
TGGTATCAGCACCCAAGAGCTTCGCCAGATCCCCTGCGTTATCGCTATCGCCGCTGAAAACACCAAAGCATTAGCGCTGC
TGGGTGCCTTGCGTACCGGTGCGATCGATATTCTTGCGACCAGTGCATCCAATGCCCGGACTATTTTGAAGATGATTCAA
CATCAGTCGTAA

Upstream 100 bases:

>100_bases
TACTATACAAATGCTCTACTATTCATTCCTGTTTAAAACAATAACCCTTCACCTTATGTGATACGTTCCGAGTGTGATAA
GTGGCCGAGGGCAGCTCTCT

Downstream 100 bases:

>100_bases
TATTACAGACAGATAAAAGAGAGATAAAAAGACCAATAGCGATTGGGGCAGTCTCGTGACTGAGTGCCCACATCGCTTCT
TCACCTGAATACCACGGTCA

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MEKQMIPQDNELLTEIAVSYYQDEMTQEEIAHKFGISRIKVGRLLKRAKTEGIVEINVRYHPVFSTRLEQQLIEHFGLKR
ALIALDYQDEDEQRRQVAALVSAYLATNLKDNTVLAVGQGRNVAAIADHVSVVPERHCKFICGIGGTHRPGDAINADHIS
RRLAKKFGGTSETLYAPAYVENRALKEAFMQNGTIKETLDRARKADMALVGIGDMNENSYMVELGWFTPQEIVDASLHQG
VTGEIAGYDFFDAQGQPANTVMNDRVIGISTQELRQIPCVIAIAAENTKALALLGALRTGAIDILATSASNARTILKMIQ
HQS

Sequences:

>Translated_323_residues
MEKQMIPQDNELLTEIAVSYYQDEMTQEEIAHKFGISRIKVGRLLKRAKTEGIVEINVRYHPVFSTRLEQQLIEHFGLKR
ALIALDYQDEDEQRRQVAALVSAYLATNLKDNTVLAVGQGRNVAAIADHVSVVPERHCKFICGIGGTHRPGDAINADHIS
RRLAKKFGGTSETLYAPAYVENRALKEAFMQNGTIKETLDRARKADMALVGIGDMNENSYMVELGWFTPQEIVDASLHQG
VTGEIAGYDFFDAQGQPANTVMNDRVIGISTQELRQIPCVIAIAAENTKALALLGALRTGAIDILATSASNARTILKMIQ
HQS
>Mature_323_residues
MEKQMIPQDNELLTEIAVSYYQDEMTQEEIAHKFGISRIKVGRLLKRAKTEGIVEINVRYHPVFSTRLEQQLIEHFGLKR
ALIALDYQDEDEQRRQVAALVSAYLATNLKDNTVLAVGQGRNVAAIADHVSVVPERHCKFICGIGGTHRPGDAINADHIS
RRLAKKFGGTSETLYAPAYVENRALKEAFMQNGTIKETLDRARKADMALVGIGDMNENSYMVELGWFTPQEIVDASLHQG
VTGEIAGYDFFDAQGQPANTVMNDRVIGISTQELRQIPCVIAIAAENTKALALLGALRTGAIDILATSASNARTILKMIQ
HQS

Specific function: Regulates transcription of many different genes. In the absence of autoinducer 2 (AI-2), represses transcription of the lsrACDBFG operon and its own transcription. In the presence of AI- 2, lsrR is inactivated by binding phospho-AI-2, leading to the trans

COG id: COG2390

COG function: function code K; Transcriptional regulator, contains sigma factor-related N-terminal domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sorC transcriptional regulatory family [H]

Homologues:

Organism=Escherichia coli, GI1787791, Length=318, Percent_Identity=26.7295597484277, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI87082414, Length=303, Percent_Identity=25.4125412541254, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04198 Sugar-bind [H]

EC number: NA

Molecular weight: Translated: 35691; Mature: 35691

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKQMIPQDNELLTEIAVSYYQDEMTQEEIAHKFGISRIKVGRLLKRAKTEGIVEINVRY
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEEEE
HPVFSTRLEQQLIEHFGLKRALIALDYQDEDEQRRQVAALVSAYLATNLKDNTVLAVGQG
ECHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
RNVAAIADHVSVVPERHCKFICGIGGTHRPGDAINADHISRRLAKKFGGTSETLYAPAYV
CCEEHHHHHHHHCCHHHCEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCHHH
ENRALKEAFMQNGTIKETLDRARKADMALVGIGDMNENSYMVELGWFTPQEIVDASLHQG
HHHHHHHHHHCCCCHHHHHHHHHHCCEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHCC
VTGEIAGYDFFDAQGQPANTVMNDRVIGISTQELRQIPCVIAIAAENTKALALLGALRTG
CCCCCCCCEEECCCCCCCCHHHCCEEEECCHHHHHHCCEEEEEECCCCHHHHHHHHHHHC
AIDILATSASNARTILKMIQHQS
CEEEEEECCCHHHHHHHHHHCCC
>Mature Secondary Structure
MEKQMIPQDNELLTEIAVSYYQDEMTQEEIAHKFGISRIKVGRLLKRAKTEGIVEINVRY
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEEEE
HPVFSTRLEQQLIEHFGLKRALIALDYQDEDEQRRQVAALVSAYLATNLKDNTVLAVGQG
ECHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
RNVAAIADHVSVVPERHCKFICGIGGTHRPGDAINADHISRRLAKKFGGTSETLYAPAYV
CCEEHHHHHHHHCCHHHCEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCHHH
ENRALKEAFMQNGTIKETLDRARKADMALVGIGDMNENSYMVELGWFTPQEIVDASLHQG
HHHHHHHHHHCCCCHHHHHHHHHHCCEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHCC
VTGEIAGYDFFDAQGQPANTVMNDRVIGISTQELRQIPCVIAIAAENTKALALLGALRTG
CCCCCCCCEEECCCCCCCCHHHCCEEEECCHHHHHHCCEEEEEECCCCHHHHHHHHHHHC
AIDILATSASNARTILKMIQHQS
CEEEEEECCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]