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The map label for this gene is idhA [H]

Identifier: 170025267

GI number: 170025267

Start: 3348038

End: 3349024

Strand: Reverse

Name: idhA [H]

Synonym: YPK_3046

Alternate gene names: 170025267

Gene position: 3349024-3348038 (Counterclockwise)

Preceding gene: 170025268

Following gene: 170025266

Centisome position: 71.42

GC content: 55.62

Gene sequence:

>987_bases
ATGTTTAACATTGCCTTACTGGGCGCAGGCCGCATCGGCCAGGTTCACGCCGCCAATATTGCCGCCCACCCAGAGACCAC
CCTCTGGTCTGTGGTGGATCCCAATCAGGAAAACGCGGCTCGCCTCGTATCACAGTATCGGACCCGTCAGCAGAGTGTGA
ATGAGGCCATGGCAGATCTGAACGTCCACGCGGTGTTGATCGCTTCCGCCACCGATACTCATGCTGATTTGATTGAGCTG
GCAGCAAAACACGGCAAAACCATTTTCTGCGAAAAACCGGTCCATCTCGATCTTGCCCGTGTGCGGGATTGCCTAAAAGT
CGTGAAAGAGTATGGGGTGCCGCTGTTTATCGGTTTTAACCGCCGCTTCGATCCACAGTTTCGGCACCTCAAAAACGAGG
TGTTGGCAGGGCGCATTGGTAAACCGGAATCGTTACTGATTATCTCCCGCGACCCGTCGCCCCCCCCGGTGGAGTATGTG
CGCGTTTCCGGCGGTATGTTCCGTGATATGACCATCCACGACTTTGACATGGCGCGTTTCATCATGGGCGAAGAACCGGT
TGCCGTATTTGCTCAGGGTAGCAATTTAGTGGATCCCGCCATTGGTGCGGCTGGCGATATCGACACCGCGTTTGTGGTGC
TGAAATACGCCTCTGGCGCGATGGCGACCATCGTCAACAGCCGCCGCTCGGCTTATGGTTACGACCAGCGGTTAGAACTG
CATGGATCGCAGGGGTTGCTGTGCGTGGGCAATATTCTGGAAAACCAGGTACAGCACTTTGGCCAAAAGGGGGGTACCCG
TGCGTTACCGGAGCATTTCTTCCTGCAACGTTATCAAGCCGCCTATGCTGCGGAATGGGAACACTTTGTCGCTATTTTAC
GCGGCGATGTGCAACCGGAATGCGGTGGTGAAGAGGGTGAGCGGGCGTTGTATTTGGCCGACAAAGCGCTGGAATCGTTG
CACAGCCAGCGTGAAATCTCCCTGTAA

Upstream 100 bases:

>100_bases
GCAAAGGTTATACCGCAGTATTGCTTTCGCGGTGTACCCCAGTTTTTAGGGGGGATTACCAGACCACCGAGATATCGCTA
GATCAGGAGCAGGAGCCGCT

Downstream 100 bases:

>100_bases
ATTTTGACCGACCTTACAGCATCTATCGATCTTACAACATCTATCGATTCTACAACCCTCTAGACCTTACAACCGTACCG
ACCCTACAACGATAAAGAGA

Product: inositol 2-dehydrogenase

Products: NA

Alternate protein names: Myo-inositol 2-dehydrogenase; MI-dehydrogenase [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MFNIALLGAGRIGQVHAANIAAHPETTLWSVVDPNQENAARLVSQYRTRQQSVNEAMADLNVHAVLIASATDTHADLIEL
AAKHGKTIFCEKPVHLDLARVRDCLKVVKEYGVPLFIGFNRRFDPQFRHLKNEVLAGRIGKPESLLIISRDPSPPPVEYV
RVSGGMFRDMTIHDFDMARFIMGEEPVAVFAQGSNLVDPAIGAAGDIDTAFVVLKYASGAMATIVNSRRSAYGYDQRLEL
HGSQGLLCVGNILENQVQHFGQKGGTRALPEHFFLQRYQAAYAAEWEHFVAILRGDVQPECGGEEGERALYLADKALESL
HSQREISL

Sequences:

>Translated_328_residues
MFNIALLGAGRIGQVHAANIAAHPETTLWSVVDPNQENAARLVSQYRTRQQSVNEAMADLNVHAVLIASATDTHADLIEL
AAKHGKTIFCEKPVHLDLARVRDCLKVVKEYGVPLFIGFNRRFDPQFRHLKNEVLAGRIGKPESLLIISRDPSPPPVEYV
RVSGGMFRDMTIHDFDMARFIMGEEPVAVFAQGSNLVDPAIGAAGDIDTAFVVLKYASGAMATIVNSRRSAYGYDQRLEL
HGSQGLLCVGNILENQVQHFGQKGGTRALPEHFFLQRYQAAYAAEWEHFVAILRGDVQPECGGEEGERALYLADKALESL
HSQREISL
>Mature_328_residues
MFNIALLGAGRIGQVHAANIAAHPETTLWSVVDPNQENAARLVSQYRTRQQSVNEAMADLNVHAVLIASATDTHADLIEL
AAKHGKTIFCEKPVHLDLARVRDCLKVVKEYGVPLFIGFNRRFDPQFRHLKNEVLAGRIGKPESLLIISRDPSPPPVEYV
RVSGGMFRDMTIHDFDMARFIMGEEPVAVFAQGSNLVDPAIGAAGDIDTAFVVLKYASGAMATIVNSRRSAYGYDQRLEL
HGSQGLLCVGNILENQVQHFGQKGGTRALPEHFFLQRYQAAYAAEWEHFVAILRGDVQPECGGEEGERALYLADKALESL
HSQREISL

Specific function: Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) [H]

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI87082405, Length=254, Percent_Identity=25.9842519685039, Blast_Score=78, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: =1.1.1.18 [H]

Molecular weight: Translated: 36186; Mature: 36186

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNIALLGAGRIGQVHAANIAAHPETTLWSVVDPNQENAARLVSQYRTRQQSVNEAMADL
CEEEEEECCCCCCCEEECEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCC
NVHAVLIASATDTHADLIELAAKHGKTIFCEKPVHLDLARVRDCLKVVKEYGVPLFIGFN
CEEEEEEEECCCCHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEECC
RRFDPQFRHLKNEVLAGRIGKPESLLIISRDPSPPPVEYVRVSGGMFRDMTIHDFDMARF
CCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEECCCEEECCEECHHHHHHH
IMGEEPVAVFAQGSNLVDPAIGAAGDIDTAFVVLKYASGAMATIVNSRRSAYGYDQRLEL
HCCCCCEEEEECCCCCCCCCCCCCCCCHHHEEEEECCCCHHHHHHHHHHHHCCCCCEEEE
HGSQGLLCVGNILENQVQHFGQKGGTRALPEHFFLQRYQAAYAAEWEHFVAILRGDVQPE
CCCCCEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
CGGEEGERALYLADKALESLHSQREISL
CCCCCCCEEEEEHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFNIALLGAGRIGQVHAANIAAHPETTLWSVVDPNQENAARLVSQYRTRQQSVNEAMADL
CEEEEEECCCCCCCEEECEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCC
NVHAVLIASATDTHADLIELAAKHGKTIFCEKPVHLDLARVRDCLKVVKEYGVPLFIGFN
CEEEEEEEECCCCHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEECC
RRFDPQFRHLKNEVLAGRIGKPESLLIISRDPSPPPVEYVRVSGGMFRDMTIHDFDMARF
CCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEECCCEEECCEECHHHHHHH
IMGEEPVAVFAQGSNLVDPAIGAAGDIDTAFVVLKYASGAMATIVNSRRSAYGYDQRLEL
HCCCCCEEEEECCCCCCCCCCCCCCCCHHHEEEEECCCCHHHHHHHHHHHHCCCCCEEEE
HGSQGLLCVGNILENQVQHFGQKGGTRALPEHFFLQRYQAAYAAEWEHFVAILRGDVQPE
CCCCCEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
CGGEEGERALYLADKALESLHSQREISL
CCCCCCCEEEEEHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9802033; 11481431 [H]