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The map label for this gene is iolB [H]

Identifier: 170025260

GI number: 170025260

Start: 3339237

End: 3340052

Strand: Reverse

Name: iolB [H]

Synonym: YPK_3039

Alternate gene names: 170025260

Gene position: 3340052-3339237 (Counterclockwise)

Preceding gene: 170025261

Following gene: 170025259

Centisome position: 71.22

GC content: 53.19

Gene sequence:

>816_bases
ATGTCACGTTTATTATCACGCAGGCAGGCACCGGATGAGCGGGGCCTGACGCAGCGAATCACTCCAGCGCAGGCGGGCTG
GGGGTATGTGGGGTTTGAGGTGTATGAACTGAATGAAGGGCAGCCACTGACGCTCACCGCGGTTCCCGATGAGCGTTGCT
TGGTTTTGATCGCTGGGCGCGCCAGTATCAGTACGCCCAGCGCACAATTCCCTAACATAGGTGATCGCATGAGCCCGTTT
GAGCGCCATAAACCTTGGGCGGTGTATGTCACTCCGGGCGAAGCGGTACAGGTGCAGGCCATTACCCCGCTTGAACTGGC
GGTTTGTTCCGCCCCCGGTAAAGGCACTTACCCAACCCGGCTGATTTCGCCAGAGGATATCGGCGCAGAAGCGCGCGGTA
AGGGTCATAACCAGCGCTATGTACACAACATTTTGCCAGAAGATCACCCCGCCGATAGCCTGCTGGTGGTGGAGGTTTAT
ACCAACGAAGGGGCGAGCAGTTCATACCCGAGCCACAAACATGACACTGACAACCCACCACACGAAACTTATCTGGAAGA
GACCTATTATCACCGCCTTAATCCAGAGCAGGGCTTCTGTATGCAGCGTGTTTATACTGATGACCGCTCACTTGATGAAT
GTATGGCGGTTTACAACCGCGAGGTGGTCATGGTGCCAAAAGGTTATCACCCAGTAGCGACGATGGCAGGCTATGACAGC
TATTATCTGAATGTAATGGCTGGTCCGGTACGTAAATGGATATTTAGCTGGGAAAGCGAGCATGTTTGGATAAATCATAA
TTATCCTATTACATAA

Upstream 100 bases:

>100_bases
GCAAGATCCTAATGTCGCCCACCCAATGACCTATGCGCGCATGGGCTACCACAATTTAAGCCGTCTGGCACATAACGCTG
GGCTGATTTAAGGGGGTCAT

Downstream 100 bases:

>100_bases
ATTGTTTATTATGTAATAGGTTGCTTGTTAATTAGTCAACAAGAAAAGGATTAAAGTTTTATTGTGAATAACCAAATCGC
TTTGTTTTTATTCGTTTGAG

Product: myo-inositol catabolism IolB domain-containing protein

Products: NA

Alternate protein names: 5DG isomerase [H]

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MSRLLSRRQAPDERGLTQRITPAQAGWGYVGFEVYELNEGQPLTLTAVPDERCLVLIAGRASISTPSAQFPNIGDRMSPF
ERHKPWAVYVTPGEAVQVQAITPLELAVCSAPGKGTYPTRLISPEDIGAEARGKGHNQRYVHNILPEDHPADSLLVVEVY
TNEGASSSYPSHKHDTDNPPHETYLEETYYHRLNPEQGFCMQRVYTDDRSLDECMAVYNREVVMVPKGYHPVATMAGYDS
YYLNVMAGPVRKWIFSWESEHVWINHNYPIT

Sequences:

>Translated_271_residues
MSRLLSRRQAPDERGLTQRITPAQAGWGYVGFEVYELNEGQPLTLTAVPDERCLVLIAGRASISTPSAQFPNIGDRMSPF
ERHKPWAVYVTPGEAVQVQAITPLELAVCSAPGKGTYPTRLISPEDIGAEARGKGHNQRYVHNILPEDHPADSLLVVEVY
TNEGASSSYPSHKHDTDNPPHETYLEETYYHRLNPEQGFCMQRVYTDDRSLDECMAVYNREVVMVPKGYHPVATMAGYDS
YYLNVMAGPVRKWIFSWESEHVWINHNYPIT
>Mature_270_residues
SRLLSRRQAPDERGLTQRITPAQAGWGYVGFEVYELNEGQPLTLTAVPDERCLVLIAGRASISTPSAQFPNIGDRMSPFE
RHKPWAVYVTPGEAVQVQAITPLELAVCSAPGKGTYPTRLISPEDIGAEARGKGHNQRYVHNILPEDHPADSLLVVEVYT
NEGASSSYPSHKHDTDNPPHETYLEETYYHRLNPEQGFCMQRVYTDDRSLDECMAVYNREVVMVPKGYHPVATMAGYDSY
YLNVMAGPVRKWIFSWESEHVWINHNYPIT

Specific function: Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate) [H]

COG id: COG3718

COG function: function code G; Uncharacterized enzyme involved in inositol metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isomerase iolB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR021120
- InterPro:   IPR014710 [H]

Pfam domain/function: PF04962 KduI [H]

EC number: NA

Molecular weight: Translated: 30595; Mature: 30463

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLLSRRQAPDERGLTQRITPAQAGWGYVGFEVYELNEGQPLTLTAVPDERCLVLIAGR
CCHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEEECCCCCEEEEEECC
ASISTPSAQFPNIGDRMSPFERHKPWAVYVTPGEAVQVQAITPLELAVCSAPGKGTYPTR
CCCCCCCCCCCCCCCCCCHHHHCCCEEEEECCCCEEEEEEECCEEEEEECCCCCCCCCEE
LISPEDIGAEARGKGHNQRYVHNILPEDHPADSLLVVEVYTNEGASSSYPSHKHDTDNPP
EECHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCC
HETYLEETYYHRLNPEQGFCMQRVYTDDRSLDECMAVYNREVVMVPKGYHPVATMAGYDS
HHHHHHHHHHHCCCCCCCCEEHHHHCCCCCHHHHHHHHCCCEEEECCCCCCHHHHCCCCE
YYLNVMAGPVRKWIFSWESEHVWINHNYPIT
EEEEEEHHHHHHHHCCCCCCEEEEECCCCCC
>Mature Secondary Structure 
SRLLSRRQAPDERGLTQRITPAQAGWGYVGFEVYELNEGQPLTLTAVPDERCLVLIAGR
CHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEEECCCCCEEEEEECC
ASISTPSAQFPNIGDRMSPFERHKPWAVYVTPGEAVQVQAITPLELAVCSAPGKGTYPTR
CCCCCCCCCCCCCCCCCCHHHHCCCEEEEECCCCEEEEEEECCEEEEEECCCCCCCCCEE
LISPEDIGAEARGKGHNQRYVHNILPEDHPADSLLVVEVYTNEGASSSYPSHKHDTDNPP
EECHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCC
HETYLEETYYHRLNPEQGFCMQRVYTDDRSLDECMAVYNREVVMVPKGYHPVATMAGYDS
HHHHHHHHHHHCCCCCCCCEEHHHHCCCCCHHHHHHHHCCCEEEECCCCCCHHHHCCCCE
YYLNVMAGPVRKWIFSWESEHVWINHNYPIT
EEEEEEHHHHHHHHCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA