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The map label for this gene is sulA

Identifier: 170024854

GI number: 170024854

Start: 2884883

End: 2885389

Strand: Direct

Name: sulA

Synonym: YPK_2629

Alternate gene names: 170024854

Gene position: 2884883-2885389 (Clockwise)

Preceding gene: 170024852

Following gene: 170024855

Centisome position: 61.52

GC content: 40.24

Gene sequence:

>507_bases
ATGCGTACTCAATCACTTAAACCTTATCATGCTAATTATCATTCTCTTACTACCAACGATTCTCCAGCAAGAGTTGATGC
TCCAACCGATAGCGGCCTTATCAGTGAATTTGTTTACAGTGAAAATCAACCCGTAGTAACGCAATTATTACTTCCTTTAT
TACAGCAGCTTAGTAAACAATCTCGTTGGCTTTTATGGCTCACCCCACAACAGAAATTAAGCCGTTCATGGTTAAAGCAA
TCAGGGCTGCCAATCAATAAAGTTGTGCAACTCAGGCAAATCAATCCATTATCGACCGTTGAGGCCATGGAAAAAGCATT
ATTAACCGGTAATTACAGTGTTGTTCTGGGCTGGTTACCCGAATTGACGGAAGATGATCGTATCAGATTACGTTTAGCCG
CGAAGTTAGGAAATGCTTATGGGTTTGTTATGCGCCCATTGAATGACACAAAAGTGGGTTCAGGACAGTGCGCCACGTTA
AAAATTCATTCTTATTTGTATCATTAA

Upstream 100 bases:

>100_bases
TTGCATCACAATTATGCGAAGCGTCTTATAAAATTTAGTTGATCTTCGATTAAACAGTGACTACTGTATATACATACAGC
ACACTACAGGCGGGTTCATA

Downstream 100 bases:

>100_bases
GTGAATTTAGGATTTATCCCATGAATAATCACAATATTCAGAATTTAGCCCTAAAGAAGTGGCGAAAATCGAGTCAGAAT
GCGGCTTGACGAATAAAATA

Product: SOS cell division inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 168; Mature: 168

Protein sequence:

>168_residues
MRTQSLKPYHANYHSLTTNDSPARVDAPTDSGLISEFVYSENQPVVTQLLLPLLQQLSKQSRWLLWLTPQQKLSRSWLKQ
SGLPINKVVQLRQINPLSTVEAMEKALLTGNYSVVLGWLPELTEDDRIRLRLAAKLGNAYGFVMRPLNDTKVGSGQCATL
KIHSYLYH

Sequences:

>Translated_168_residues
MRTQSLKPYHANYHSLTTNDSPARVDAPTDSGLISEFVYSENQPVVTQLLLPLLQQLSKQSRWLLWLTPQQKLSRSWLKQ
SGLPINKVVQLRQINPLSTVEAMEKALLTGNYSVVLGWLPELTEDDRIRLRLAAKLGNAYGFVMRPLNDTKVGSGQCATL
KIHSYLYH
>Mature_168_residues
MRTQSLKPYHANYHSLTTNDSPARVDAPTDSGLISEFVYSENQPVVTQLLLPLLQQLSKQSRWLLWLTPQQKLSRSWLKQ
SGLPINKVVQLRQINPLSTVEAMEKALLTGNYSVVLGWLPELTEDDRIRLRLAAKLGNAYGFVMRPLNDTKVGSGQCATL
KIHSYLYH

Specific function: Component of the SOS system and an inhibitor of cell division. Accumulation of sulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of ftsZ in a 1:1 r

COG id: COG5404

COG function: function code D; SOS-response cell division inhibitor, blocks FtsZ ring formation

Gene ontology:

Cell location: Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulA family

Homologues:

Organism=Escherichia coli, GI1787192, Length=149, Percent_Identity=57.0469798657718, Blast_Score=147, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SULA_YERP3 (A7FJS7)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001401505.1
- ProteinModelPortal:   A7FJS7
- SMR:   A7FJS7
- STRING:   A7FJS7
- GeneID:   5386241
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_2540
- eggNOG:   COG5404
- HOGENOM:   HBG416377
- OMA:   EWVQSAG
- ProtClustDB:   PRK10595
- BioCyc:   YPSE349747:YPSIP31758_2540-MONOMER
- HAMAP:   MF_01179
- InterPro:   IPR004596
- PIRSF:   PIRSF003093

Pfam domain/function: PF03846 SulA

EC number: NA

Molecular weight: Translated: 19030; Mature: 19030

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTQSLKPYHANYHSLTTNDSPARVDAPTDSGLISEFVYSENQPVVTQLLLPLLQQLSKQ
CCCCCCCCCCCCCCEECCCCCCCEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHC
SRWLLWLTPQQKLSRSWLKQSGLPINKVVQLRQINPLSTVEAMEKALLTGNYSVVLGWLP
CCEEEEECCHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCC
ELTEDDRIRLRLAAKLGNAYGFVMRPLNDTKVGSGQCATLKIHSYLYH
CCCCCCCEEEEEEEHHCCCCEEEEECCCCCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MRTQSLKPYHANYHSLTTNDSPARVDAPTDSGLISEFVYSENQPVVTQLLLPLLQQLSKQ
CCCCCCCCCCCCCCEECCCCCCCEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHC
SRWLLWLTPQQKLSRSWLKQSGLPINKVVQLRQINPLSTVEAMEKALLTGNYSVVLGWLP
CCEEEEECCHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCC
ELTEDDRIRLRLAAKLGNAYGFVMRPLNDTKVGSGQCATLKIHSYLYH
CCCCCCCEEEEEEEHHCCCCEEEEECCCCCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA