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The map label for this gene is fimB [H]

Identifier: 170024501

GI number: 170024501

Start: 2529944

End: 2530684

Strand: Direct

Name: fimB [H]

Synonym: YPK_2276

Alternate gene names: 170024501

Gene position: 2529944-2530684 (Clockwise)

Preceding gene: 170024500

Following gene: 170024508

Centisome position: 53.95

GC content: 43.72

Gene sequence:

>741_bases
ATGAGATTACTGAGCCTGTTTTTACTGTTATTCACGATCAGCTACGATGCACTGGCCGGTTTGATCGCCGGATCTACCCG
CATTATTTATCAGCCTGAGTTACGTGAGCGCACGCTTATGCTGGCTAATACTAATGATTATCCCGTCGTCGTGCAGACTT
GGATTGATAACGGCGATGTGGACAGTACGCCGGATCAGGCTAAGGCCCCTTTTATGGTATTGCCTGCCGTGTTTAAAATG
CAGGCAGGATCGGTTCAGGCACTACGCATCATCAATAAAGGTGAAAACCTTCCCAGTGACCGAGAGTCTGTCTATTGGTT
GAATTTGTATGAAATACCGCCCAGAGAACGGAGTAACATTGATGTTCATGCACAAGTTGCCATGGCAATGAATACACAAA
TGAAGATTTTTTATCGACCAAACGGATTAGCCCCGCCCCCCATCGATGCCATGGGTAAGATAAAATTTTCACTTAAAAAT
ATTGATAATCAATACGTTATAATCGCGAATAATCCCACGCCTTATTTTGTCTCTTTTGGCCAGATTCAGTTACAGAGCCA
ACAAAAAAACTACCTGATTGCACAGTCGATGGATATGATGACCGGCCCATTCTCCACACGACCCTATTATTTTGAACAGC
CTCCCACCTCACTTAAAGGCAAGTTTACCGTCAGTTATATTTATTTTGATGATGCGGGTAACCAAGTTAAAAACAGCCAG
TCAGTGACGGTAACGCTATAA

Upstream 100 bases:

>100_bases
ATTATGTCCATCACTTCACCGCCACCTTAAAAAAACTGCCTAATGGTCACCCTACTGCGGGGAAGATCGACGCCACAGCT
TACGTTCTGGTGAAAATACA

Downstream 100 bases:

>100_bases
CAGATTTTTATTTTTCGCCCTTCCCCCGTTATGTATTCAATAACGACAGTACTGCCTTACCCTAATCCTCGCCACTCGCC
CCAACAAATATGAACGTATC

Product: pili assembly chaperone

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MRLLSLFLLLFTISYDALAGLIAGSTRIIYQPELRERTLMLANTNDYPVVVQTWIDNGDVDSTPDQAKAPFMVLPAVFKM
QAGSVQALRIINKGENLPSDRESVYWLNLYEIPPRERSNIDVHAQVAMAMNTQMKIFYRPNGLAPPPIDAMGKIKFSLKN
IDNQYVIIANNPTPYFVSFGQIQLQSQQKNYLIAQSMDMMTGPFSTRPYYFEQPPTSLKGKFTVSYIYFDDAGNQVKNSQ
SVTVTL

Sequences:

>Translated_246_residues
MRLLSLFLLLFTISYDALAGLIAGSTRIIYQPELRERTLMLANTNDYPVVVQTWIDNGDVDSTPDQAKAPFMVLPAVFKM
QAGSVQALRIINKGENLPSDRESVYWLNLYEIPPRERSNIDVHAQVAMAMNTQMKIFYRPNGLAPPPIDAMGKIKFSLKN
IDNQYVIIANNPTPYFVSFGQIQLQSQQKNYLIAQSMDMMTGPFSTRPYYFEQPPTSLKGKFTVSYIYFDDAGNQVKNSQ
SVTVTL
>Mature_246_residues
MRLLSLFLLLFTISYDALAGLIAGSTRIIYQPELRERTLMLANTNDYPVVVQTWIDNGDVDSTPDQAKAPFMVLPAVFKM
QAGSVQALRIINKGENLPSDRESVYWLNLYEIPPRERSNIDVHAQVAMAMNTQMKIFYRPNGLAPPPIDAMGKIKFSLKN
IDNQYVIIANNPTPYFVSFGQIQLQSQQKNYLIAQSMDMMTGPFSTRPYYFEQPPTSLKGKFTVSYIYFDDAGNQVKNSQ
SVTVTL

Specific function: Required for the biogenesis of the filamentous hemagglutinin and the fimbria [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Ig-like (immunoglobulin-like) domain [H]

Homologues:

Organism=Escherichia coli, GI1786333, Length=202, Percent_Identity=31.1881188118812, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1789532, Length=180, Percent_Identity=33.3333333333333, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788428, Length=140, Percent_Identity=37.8571428571429, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1790771, Length=179, Percent_Identity=30.1675977653631, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1786743, Length=187, Percent_Identity=30.4812834224599, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787171, Length=198, Percent_Identity=27.7777777777778, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1786936, Length=202, Percent_Identity=25.2475247524752, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87082203, Length=228, Percent_Identity=26.3157894736842, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788677, Length=171, Percent_Identity=32.1637426900585, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87081806, Length=195, Percent_Identity=23.5897435897436, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008962
- InterPro:   IPR001829
- InterPro:   IPR016148
- InterPro:   IPR018046
- InterPro:   IPR016147 [H]

Pfam domain/function: PF02753 Pili_assembly_C; PF00345 Pili_assembly_N [H]

EC number: NA

Molecular weight: Translated: 27826; Mature: 27826

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS00635 PILI_CHAPERONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLSLFLLLFTISYDALAGLIAGSTRIIYQPELRERTLMLANTNDYPVVVQTWIDNGDV
CHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEECCCCCCEEEEEEECCCCC
DSTPDQAKAPFMVLPAVFKMQAGSVQALRIINKGENLPSDRESVYWLNLYEIPPRERSNI
CCCCCHHCCCEEEECHHEEECCCCEEEEEEEECCCCCCCCCCEEEEEEEEECCCCCCCCC
DVHAQVAMAMNTQMKIFYRPNGLAPPPIDAMGKIKFSLKNIDNQYVIIANNPTPYFVSFG
EEEEEEEEEECCEEEEEECCCCCCCCCCCCCEEEEEEEECCCCCEEEEECCCCCEEEEEC
QIQLQSQQKNYLIAQSMDMMTGPFSTRPYYFEQPPTSLKGKFTVSYIYFDDAGNQVKNSQ
EEEEECCCCCEEEEECCHHHCCCCCCCCEEECCCCCCCCCEEEEEEEEECCCCCCCCCCC
SVTVTL
EEEEEC
>Mature Secondary Structure
MRLLSLFLLLFTISYDALAGLIAGSTRIIYQPELRERTLMLANTNDYPVVVQTWIDNGDV
CHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEECCCCCCEEEEEEECCCCC
DSTPDQAKAPFMVLPAVFKMQAGSVQALRIINKGENLPSDRESVYWLNLYEIPPRERSNI
CCCCCHHCCCEEEECHHEEECCCCEEEEEEEECCCCCCCCCCEEEEEEEEECCCCCCCCC
DVHAQVAMAMNTQMKIFYRPNGLAPPPIDAMGKIKFSLKNIDNQYVIIANNPTPYFVSFG
EEEEEEEEEECCEEEEEECCCCCCCCCCCCCEEEEEEEECCCCCEEEEECCCCCEEEEEC
QIQLQSQQKNYLIAQSMDMMTGPFSTRPYYFEQPPTSLKGKFTVSYIYFDDAGNQVKNSQ
EEEEECCCCCEEEEECCHHHCCCCCCCCEEECCCCCCCCCEEEEEEEEECCCCCCCCCCC
SVTVTL
EEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1360139; 1354611; 12910271 [H]