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The map label for this gene is cat2 [H]

Identifier: 170024495

GI number: 170024495

Start: 2517451

End: 2518773

Strand: Direct

Name: cat2 [H]

Synonym: YPK_2268

Alternate gene names: 170024495

Gene position: 2517451-2518773 (Clockwise)

Preceding gene: 170024494

Following gene: 170024496

Centisome position: 53.68

GC content: 50.19

Gene sequence:

>1323_bases
ATGGATATACGTGCATTGTATGACGAGAAACTCACCACGCCTGAGGAGGCCGTTTCCTCTATTGCATCCGGCAGTCATCT
CTCTATGGGGATGTTTGCGGCTGAACCACCCGCGCTGCTGAAGGCGCTGGCAGATAGGGCGACAAGGGGGGATATTGGCG
ATCTACGCGTTTACTATTTTGAAACGGCCAAAATTGCCGGTGATACTATTCTGCGCTATGAGCTAAATAATCGCATCAAG
CCCTATAGCATGTTCGTCACTGCCGTGGAGCGGGCGCTCATTCGCCGAGGTATAGAGGATGGTGGGCGTAAAGTTGTCAA
TTATGTCCCATCCAATTTTCATCAAGCACCACGTCTTCTGGCCGAAGAAATTGGTATTGATACGTTCATGCACACCGTTT
CTCCGATGGATTGCCATGGCTACTTTAGCCTCGGTGTTGGAAATGACTATTCATCCCGAATTGCACGTTCAGCCAGACGA
TTCATCGTTGAGGTGAATCGGTATATGCCGCGCGTTCAGGGGGAAGCGGCGGCGATTCACATCTCTGAAGTTGATGCCAT
TGTCGAAAATCATGTCCCTTTGATTGAGATGCCAGTACGTTCAGCAATACCCGAATATACATCTATTAGCCACATCATTG
CTGACCTCGTACCTGATGGTGCCTGCTTACAAATGGGGGTGGGCGCACTACCAAACCTCGTTTGTGGAGTGCTAAAAGAG
CGCAATGACCTAGGGATCCATACTGAAGTGTTGAACCCCGGACTGGTCGATTTAATCCGAAGGGGGGTAGTGACGAACCA
GCGAAAAACACTGGATAGGGGCAGGTCTGTTTTCACTTTTGCCATGGGGCAACAAGAAATGTACGAATACCTTAACGATC
ACCCAGCGATTTTCAGCCGGCCGGTCGATTATGTTAACGATCCCCACATCATTGCGCAAAATGACAACGTGGTATCCATT
AATGCGACCCTGCAAATTGACCTGACGGGTGCCTGCAATTCTGAACATATGCTTGGACACCAATACAGCGCTTCGGGGGG
GCAGTTGGACTTTGTCAGGGGGGCATACGCCTCTAAAGGTGGGCGCTCCATCATCGCCACGCCTTCAACTGCGGCGAAAG
GTACTGTTTCACGTATTATTCCCCGCATTGACGGACCGGTAACCACACCCCGTATCGATACCCACTATATCGTTACCGAG
TTTGGTGCTGTTAACCTCAAAGGACTTTCTTCAACTGAACGGGCGCTGAGAATCATTGAGCTGGCACATCCTGATTTCCG
GGATGAGCTAACGCAGGCTGCCAAAAAAATGCATCTAATCTGA

Upstream 100 bases:

>100_bases
ATAGAGGTGATGAGCTTCGAACGCACGATGCTGGTTTATCGCCGCGGTCACTCACCAGAAGAAATGGCAGGATACTGAGA
AAAACAGCGAGGGTTATATC

Downstream 100 bases:

>100_bases
GATAACCACCCTGTCAACACTCTGCCAAACAGTATTTTTCGCTCTCCGGCATGGGGAGCGCTATACGGTGTTTCCCCCTG
ACGGTCATGCAGGCGGGTGA

Product: acetyl-CoA hydrolase/transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MDIRALYDEKLTTPEEAVSSIASGSHLSMGMFAAEPPALLKALADRATRGDIGDLRVYYFETAKIAGDTILRYELNNRIK
PYSMFVTAVERALIRRGIEDGGRKVVNYVPSNFHQAPRLLAEEIGIDTFMHTVSPMDCHGYFSLGVGNDYSSRIARSARR
FIVEVNRYMPRVQGEAAAIHISEVDAIVENHVPLIEMPVRSAIPEYTSISHIIADLVPDGACLQMGVGALPNLVCGVLKE
RNDLGIHTEVLNPGLVDLIRRGVVTNQRKTLDRGRSVFTFAMGQQEMYEYLNDHPAIFSRPVDYVNDPHIIAQNDNVVSI
NATLQIDLTGACNSEHMLGHQYSASGGQLDFVRGAYASKGGRSIIATPSTAAKGTVSRIIPRIDGPVTTPRIDTHYIVTE
FGAVNLKGLSSTERALRIIELAHPDFRDELTQAAKKMHLI

Sequences:

>Translated_440_residues
MDIRALYDEKLTTPEEAVSSIASGSHLSMGMFAAEPPALLKALADRATRGDIGDLRVYYFETAKIAGDTILRYELNNRIK
PYSMFVTAVERALIRRGIEDGGRKVVNYVPSNFHQAPRLLAEEIGIDTFMHTVSPMDCHGYFSLGVGNDYSSRIARSARR
FIVEVNRYMPRVQGEAAAIHISEVDAIVENHVPLIEMPVRSAIPEYTSISHIIADLVPDGACLQMGVGALPNLVCGVLKE
RNDLGIHTEVLNPGLVDLIRRGVVTNQRKTLDRGRSVFTFAMGQQEMYEYLNDHPAIFSRPVDYVNDPHIIAQNDNVVSI
NATLQIDLTGACNSEHMLGHQYSASGGQLDFVRGAYASKGGRSIIATPSTAAKGTVSRIIPRIDGPVTTPRIDTHYIVTE
FGAVNLKGLSSTERALRIIELAHPDFRDELTQAAKKMHLI
>Mature_440_residues
MDIRALYDEKLTTPEEAVSSIASGSHLSMGMFAAEPPALLKALADRATRGDIGDLRVYYFETAKIAGDTILRYELNNRIK
PYSMFVTAVERALIRRGIEDGGRKVVNYVPSNFHQAPRLLAEEIGIDTFMHTVSPMDCHGYFSLGVGNDYSSRIARSARR
FIVEVNRYMPRVQGEAAAIHISEVDAIVENHVPLIEMPVRSAIPEYTSISHIIADLVPDGACLQMGVGALPNLVCGVLKE
RNDLGIHTEVLNPGLVDLIRRGVVTNQRKTLDRGRSVFTFAMGQQEMYEYLNDHPAIFSRPVDYVNDPHIIAQNDNVVSI
NATLQIDLTGACNSEHMLGHQYSASGGQLDFVRGAYASKGGRSIIATPSTAAKGTVSRIIPRIDGPVTTPRIDTHYIVTE
FGAVNLKGLSSTERALRIIELAHPDFRDELTQAAKKMHLI

Specific function: Unknown

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=288, Percent_Identity=28.4722222222222, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI32563853, Length=434, Percent_Identity=34.7926267281106, Blast_Score=236, Evalue=3e-62,
Organism=Caenorhabditis elegans, GI17538151, Length=437, Percent_Identity=33.8672768878719, Blast_Score=224, Evalue=7e-59,
Organism=Drosophila melanogaster, GI21358615, Length=431, Percent_Identity=34.338747099768, Blast_Score=223, Evalue=2e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro [H]

EC number: NA

Molecular weight: Translated: 48410; Mature: 48410

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIRALYDEKLTTPEEAVSSIASGSHLSMGMFAAEPPALLKALADRATRGDIGDLRVYYF
CCCHHHHHCCCCCHHHHHHHHHCCCCCEECEECCCCHHHHHHHHHHCCCCCCCCEEEEEE
ETAKIAGDTILRYELNNRIKPYSMFVTAVERALIRRGIEDGGRKVVNYVPSNFHQAPRLL
EEEHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHH
AEEIGIDTFMHTVSPMDCHGYFSLGVGNDYSSRIARSARRFIVEVNRYMPRVQGEAAAIH
HHHHCHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
ISEVDAIVENHVPLIEMPVRSAIPEYTSISHIIADLVPDGACLQMGVGALPNLVCGVLKE
HHHHHHHHHCCCCEEEECHHHCCCCHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHC
RNDLGIHTEVLNPGLVDLIRRGVVTNQRKTLDRGRSVFTFAMGQQEMYEYLNDHPAIFSR
CCCCCCCHHHCCCCHHHHHHHCCCCCHHHHHHCCCCEEEEECCHHHHHHHHCCCCCHHCC
PVDYVNDPHIIAQNDNVVSINATLQIDLTGACNSEHMLGHQYSASGGQLDFVRGAYASKG
CCCCCCCCEEEECCCCEEEEEEEEEEEEECCCCCCCCCCCEECCCCCCEEEHHCHHHCCC
GRSIIATPSTAAKGTVSRIIPRIDGPVTTPRIDTHYIVTEFGAVNLKGLSSTERALRIIE
CCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCEEECCCCHHHHHHHHHH
LAHPDFRDELTQAAKKMHLI
HCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDIRALYDEKLTTPEEAVSSIASGSHLSMGMFAAEPPALLKALADRATRGDIGDLRVYYF
CCCHHHHHCCCCCHHHHHHHHHCCCCCEECEECCCCHHHHHHHHHHCCCCCCCCEEEEEE
ETAKIAGDTILRYELNNRIKPYSMFVTAVERALIRRGIEDGGRKVVNYVPSNFHQAPRLL
EEEHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHH
AEEIGIDTFMHTVSPMDCHGYFSLGVGNDYSSRIARSARRFIVEVNRYMPRVQGEAAAIH
HHHHCHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
ISEVDAIVENHVPLIEMPVRSAIPEYTSISHIIADLVPDGACLQMGVGALPNLVCGVLKE
HHHHHHHHHCCCCEEEECHHHCCCCHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHC
RNDLGIHTEVLNPGLVDLIRRGVVTNQRKTLDRGRSVFTFAMGQQEMYEYLNDHPAIFSR
CCCCCCCHHHCCCCHHHHHHHCCCCCHHHHHHCCCCEEEEECCHHHHHHHHCCCCCHHCC
PVDYVNDPHIIAQNDNVVSINATLQIDLTGACNSEHMLGHQYSASGGQLDFVRGAYASKG
CCCCCCCCEEEECCCCEEEEEEEEEEEEECCCCCCCCCCCEECCCCCCEEEHHCHHHCCC
GRSIIATPSTAAKGTVSRIIPRIDGPVTTPRIDTHYIVTEFGAVNLKGLSSTERALRIIE
CCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCEEECCCCHHHHHHHHHH
LAHPDFRDELTQAAKKMHLI
HCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]