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The map label for this gene is ansP [H]

Identifier: 170024485

GI number: 170024485

Start: 2506283

End: 2507812

Strand: Direct

Name: ansP [H]

Synonym: YPK_2256

Alternate gene names: 170024485

Gene position: 2506283-2507812 (Clockwise)

Preceding gene: 170024484

Following gene: 170024487

Centisome position: 53.45

GC content: 48.04

Gene sequence:

>1530_bases
ATGATGTCAGGAAAACACTCTGCGGAGACCCATCACGCCGCGAAAAAACGCTGGTTAGATTCTCATGATACGGGTTACCA
CAAAAGTATGGGCCTACGTCATATACAAATGATAGCCATTGGCGGATCCATCGGAACAGGACTGTTTTTAGGTACAGGTG
CCCGCTTACAAATGGCTGGGCCAGCATTAGCACTGGTTTATCTGGTTTGTGGAATTTTTTCATTTTTCATTCTCCGGGCC
TTGGGGGAACTGGTCTTACATCGCCCTACCAGCGGCAGCTTTGTTTCTTACGCCCGTGAATTTCTCGGAGAAAAAGCATC
CTATGTCGCGGGCTGGATGTACTTCCTTAACTGGGCGATGACAGGCATCGTCGATATCACCGCAGTGGCGCTTTATATGC
ATTATTGGGGGACATTTTCTGATGTTCCGCAATGGCTGTTTGCCCTAGGCGCACTCTCGATTGTCGCTACCATGAATATG
ATTGGAGTAAGATGGTTCGCCGAAATGGAGTTTTGGTTTGCACTGATTAAAGTCGCCGCTATTGCCCTGTTTTTGATTGT
CGGTGTGATCTTCCTCGGTACGGGTCAAAGCGTCGCGGGTCATACAACTGGTATTCATTTGATTACCGACAACGGCGGTT
TCTTTCCTCACGGCCTCTTACCTGCCCTGATAATGGTACAAGGCGTTATATTCGCCTTCGCCGGTATTGAATTAATTGGC
ACTGCGGCTGGTGAATGTAAAGACCCCGAAAAAATGCTGCCAAAAGCCATTAATAGCGTGATATGGCGTATAGGTTTGTT
TTACGTTGGCTCCGTCGTCCTACTGGTCTGCTTGCTACCCTGGCATGCTTATCAAGCGGGTCAAAGCCCATTCGTGACAT
TCTTCAGTAACTTGGGGGTCCCTTACATTGGCACTATTATGAATATAGTGGTGCTATCCGCCGCACTCTCCAGTTTGAAC
TCCGGGCTTTACTCGACCGGGCGAATCCTCCGTTCACTGTCAATGGGGGGATCGGCACCTAAATTTATGTCCAAGATGAG
CCCGCAATCCGTGCCCTATGCAGGGATTTTGGTCACTGTGGGCATTTATGTCTTGGGGGTACTACTCAACTACCTCGTTC
CCTCTCAAGTTTTTGAAATTGTCCTGAATATAGCCTCCTTGGGGATCATTAGTTCATGGGCATTTATTATCATTTGTCAG
ATGAAATTACGTCAGGCAATAAAAAGAGGAATGGCAAAACCTGTCTCCTTCAAAATGCCCGGTGCGCCAGTGACATCTTG
GCTGACATTGATCTTTTTGGCGGGCGTTTTGGTGATGATGGCCTTTGACTATCCAAATGGCACCTGGACCATCGCTAGCA
TCCCCGTGCTCACACTGCTACTGATCGCCGGGTGGTTCAGTCTGCGTAAACGCGCCAATGAGGTAGCGGCCGCACCGATA
GATGTCTGGTCACAAGAAATATTGTTCGAAGAACCAGATGCTCAAAATGTATCGCCTAAAGAGTTATATGAGCAAAAATC
AGTAGGTTAA

Upstream 100 bases:

>100_bases
CTGAAGGCGCTAAGACGCTATTTATGCATTAACCTTTAGCAATCATTTGCTGTAGTACATTCACAATGATTGCCGACAGA
CAAGAATATAGGGAAAGTTT

Downstream 100 bases:

>100_bases
TACGGTTGTCATGCTGTAGCAGCCTGTAGGCCAGTTATTACACCTACAGGCTGGATTGATTTTTATAATTTATACTCGTT
ATACTTCAAGCTGCATGTGC

Product: amino acid permease-associated protein

Products: Proton [Cytoplasm]; L-asparagine [Cytoplasm] [C]

Alternate protein names: L-asparagine transport protein [H]

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MMSGKHSAETHHAAKKRWLDSHDTGYHKSMGLRHIQMIAIGGSIGTGLFLGTGARLQMAGPALALVYLVCGIFSFFILRA
LGELVLHRPTSGSFVSYAREFLGEKASYVAGWMYFLNWAMTGIVDITAVALYMHYWGTFSDVPQWLFALGALSIVATMNM
IGVRWFAEMEFWFALIKVAAIALFLIVGVIFLGTGQSVAGHTTGIHLITDNGGFFPHGLLPALIMVQGVIFAFAGIELIG
TAAGECKDPEKMLPKAINSVIWRIGLFYVGSVVLLVCLLPWHAYQAGQSPFVTFFSNLGVPYIGTIMNIVVLSAALSSLN
SGLYSTGRILRSLSMGGSAPKFMSKMSPQSVPYAGILVTVGIYVLGVLLNYLVPSQVFEIVLNIASLGIISSWAFIIICQ
MKLRQAIKRGMAKPVSFKMPGAPVTSWLTLIFLAGVLVMMAFDYPNGTWTIASIPVLTLLLIAGWFSLRKRANEVAAAPI
DVWSQEILFEEPDAQNVSPKELYEQKSVG

Sequences:

>Translated_509_residues
MMSGKHSAETHHAAKKRWLDSHDTGYHKSMGLRHIQMIAIGGSIGTGLFLGTGARLQMAGPALALVYLVCGIFSFFILRA
LGELVLHRPTSGSFVSYAREFLGEKASYVAGWMYFLNWAMTGIVDITAVALYMHYWGTFSDVPQWLFALGALSIVATMNM
IGVRWFAEMEFWFALIKVAAIALFLIVGVIFLGTGQSVAGHTTGIHLITDNGGFFPHGLLPALIMVQGVIFAFAGIELIG
TAAGECKDPEKMLPKAINSVIWRIGLFYVGSVVLLVCLLPWHAYQAGQSPFVTFFSNLGVPYIGTIMNIVVLSAALSSLN
SGLYSTGRILRSLSMGGSAPKFMSKMSPQSVPYAGILVTVGIYVLGVLLNYLVPSQVFEIVLNIASLGIISSWAFIIICQ
MKLRQAIKRGMAKPVSFKMPGAPVTSWLTLIFLAGVLVMMAFDYPNGTWTIASIPVLTLLLIAGWFSLRKRANEVAAAPI
DVWSQEILFEEPDAQNVSPKELYEQKSVG
>Mature_509_residues
MMSGKHSAETHHAAKKRWLDSHDTGYHKSMGLRHIQMIAIGGSIGTGLFLGTGARLQMAGPALALVYLVCGIFSFFILRA
LGELVLHRPTSGSFVSYAREFLGEKASYVAGWMYFLNWAMTGIVDITAVALYMHYWGTFSDVPQWLFALGALSIVATMNM
IGVRWFAEMEFWFALIKVAAIALFLIVGVIFLGTGQSVAGHTTGIHLITDNGGFFPHGLLPALIMVQGVIFAFAGIELIG
TAAGECKDPEKMLPKAINSVIWRIGLFYVGSVVLLVCLLPWHAYQAGQSPFVTFFSNLGVPYIGTIMNIVVLSAALSSLN
SGLYSTGRILRSLSMGGSAPKFMSKMSPQSVPYAGILVTVGIYVLGVLLNYLVPSQVFEIVLNIASLGIISSWAFIIICQ
MKLRQAIKRGMAKPVSFKMPGAPVTSWLTLIFLAGVLVMMAFDYPNGTWTIASIPVLTLLLIAGWFSLRKRANEVAAAPI
DVWSQEILFEEPDAQNVSPKELYEQKSVG

Specific function: Unknown

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=427, Percent_Identity=20.3747072599532, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI258645169, Length=420, Percent_Identity=21.1904761904762, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI110347453, Length=354, Percent_Identity=22.8813559322034, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI87081915, Length=497, Percent_Identity=76.6599597585513, Blast_Score=773, Evalue=0.0,
Organism=Escherichia coli, GI1786789, Length=452, Percent_Identity=38.2743362831858, Blast_Score=322, Evalue=5e-89,
Organism=Escherichia coli, GI1786302, Length=460, Percent_Identity=37.1739130434783, Blast_Score=313, Evalue=2e-86,
Organism=Escherichia coli, GI1786602, Length=450, Percent_Identity=37.3333333333333, Blast_Score=308, Evalue=7e-85,
Organism=Escherichia coli, GI1790653, Length=457, Percent_Identity=36.1050328227571, Blast_Score=301, Evalue=7e-83,
Organism=Escherichia coli, GI48994972, Length=421, Percent_Identity=38.9548693586698, Blast_Score=291, Evalue=1e-79,
Organism=Escherichia coli, GI87081708, Length=429, Percent_Identity=34.7319347319347, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI1789017, Length=413, Percent_Identity=35.1089588377724, Blast_Score=244, Evalue=8e-66,
Organism=Escherichia coli, GI1788480, Length=390, Percent_Identity=36.1538461538462, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI87081869, Length=176, Percent_Identity=23.8636363636364, Blast_Score=67, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17531343, Length=442, Percent_Identity=23.3031674208145, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17533459, Length=423, Percent_Identity=21.9858156028369, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=409, Percent_Identity=21.0268948655257, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320772, Length=445, Percent_Identity=31.9101123595506, Blast_Score=206, Evalue=6e-54,
Organism=Saccharomyces cerevisiae, GI6324061, Length=458, Percent_Identity=31.0043668122271, Blast_Score=206, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6322892, Length=426, Percent_Identity=33.3333333333333, Blast_Score=188, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6324990, Length=524, Percent_Identity=28.0534351145038, Blast_Score=179, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6321629, Length=406, Percent_Identity=28.3251231527094, Blast_Score=170, Evalue=5e-43,
Organism=Saccharomyces cerevisiae, GI6324924, Length=454, Percent_Identity=29.295154185022, Blast_Score=168, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6324059, Length=463, Percent_Identity=30.6695464362851, Blast_Score=164, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6322967, Length=419, Percent_Identity=27.9236276849642, Blast_Score=158, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6319824, Length=402, Percent_Identity=29.6019900497512, Blast_Score=154, Evalue=4e-38,
Organism=Saccharomyces cerevisiae, GI6324553, Length=399, Percent_Identity=30.8270676691729, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6324981, Length=414, Percent_Identity=28.9855072463768, Blast_Score=149, Evalue=9e-37,
Organism=Saccharomyces cerevisiae, GI6320717, Length=406, Percent_Identity=28.0788177339901, Blast_Score=146, Evalue=7e-36,
Organism=Saccharomyces cerevisiae, GI6321053, Length=455, Percent_Identity=25.4945054945055, Blast_Score=141, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6320251, Length=446, Percent_Identity=26.2331838565022, Blast_Score=139, Evalue=8e-34,
Organism=Saccharomyces cerevisiae, GI6319543, Length=417, Percent_Identity=27.8177458033573, Blast_Score=138, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6319542, Length=409, Percent_Identity=27.3838630806846, Blast_Score=134, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6319608, Length=454, Percent_Identity=26.2114537444934, Blast_Score=129, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6320364, Length=519, Percent_Identity=21.9653179190751, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI221512776, Length=414, Percent_Identity=22.2222222222222, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24666159, Length=414, Percent_Identity=22.2222222222222, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24668806, Length=431, Percent_Identity=22.5058004640371, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21356285, Length=431, Percent_Identity=22.5058004640371, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24668802, Length=431, Percent_Identity=22.5058004640371, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 55325; Mature: 55325

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSGKHSAETHHAAKKRWLDSHDTGYHKSMGLRHIQMIAIGGSIGTGLFLGTGARLQMAG
CCCCCCCHHHHHHHHHHCCCCCCCCHHHHCCCCEEEEEEECCCCCCCHHCCCCCEEEECC
PALALVYLVCGIFSFFILRALGELVLHRPTSGSFVSYAREFLGEKASYVAGWMYFLNWAM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHH
TGIVDITAVALYMHYWGTFSDVPQWLFALGALSIVATMNMIGVRWFAEMEFWFALIKVAA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IALFLIVGVIFLGTGQSVAGHTTGIHLITDNGGFFPHGLLPALIMVQGVIFAFAGIELIG
HHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TAAGECKDPEKMLPKAINSVIWRIGLFYVGSVVLLVCLLPWHAYQAGQSPFVTFFSNLGV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
PYIGTIMNIVVLSAALSSLNSGLYSTGRILRSLSMGGSAPKFMSKMSPQSVPYAGILVTV
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCHHHHHHHH
GIYVLGVLLNYLVPSQVFEIVLNIASLGIISSWAFIIICQMKLRQAIKRGMAKPVSFKMP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCC
GAPVTSWLTLIFLAGVLVMMAFDYPNGTWTIASIPVLTLLLIAGWFSLRKRANEVAAAPI
CCCHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
DVWSQEILFEEPDAQNVSPKELYEQKSVG
HHHHHHHHCCCCCCCCCCHHHHHHHCCCC
>Mature Secondary Structure
MMSGKHSAETHHAAKKRWLDSHDTGYHKSMGLRHIQMIAIGGSIGTGLFLGTGARLQMAG
CCCCCCCHHHHHHHHHHCCCCCCCCHHHHCCCCEEEEEEECCCCCCCHHCCCCCEEEECC
PALALVYLVCGIFSFFILRALGELVLHRPTSGSFVSYAREFLGEKASYVAGWMYFLNWAM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHH
TGIVDITAVALYMHYWGTFSDVPQWLFALGALSIVATMNMIGVRWFAEMEFWFALIKVAA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IALFLIVGVIFLGTGQSVAGHTTGIHLITDNGGFFPHGLLPALIMVQGVIFAFAGIELIG
HHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TAAGECKDPEKMLPKAINSVIWRIGLFYVGSVVLLVCLLPWHAYQAGQSPFVTFFSNLGV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
PYIGTIMNIVVLSAALSSLNSGLYSTGRILRSLSMGGSAPKFMSKMSPQSVPYAGILVTV
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCHHHHHHHH
GIYVLGVLLNYLVPSQVFEIVLNIASLGIISSWAFIIICQMKLRQAIKRGMAKPVSFKMP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCC
GAPVTSWLTLIFLAGVLVMMAFDYPNGTWTIASIPVLTLLLIAGWFSLRKRANEVAAAPI
CCCHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
DVWSQEILFEEPDAQNVSPKELYEQKSVG
HHHHHHHHCCCCCCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-asparagine [Periplasm]; Proton [Periplasm] [C]

Specific reaction: L-asparagine [Periplasm] + Proton [Periplasm] = Proton [Cytoplasm] + L-asparagine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]