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The map label for this gene is mbtI [H]

Identifier: 170024447

GI number: 170024447

Start: 2457139

End: 2459124

Strand: Direct

Name: mbtI [H]

Synonym: YPK_2218

Alternate gene names: 170024447

Gene position: 2457139-2459124 (Clockwise)

Preceding gene: 170024438

Following gene: 170024450

Centisome position: 52.4

GC content: 46.58

Gene sequence:

>1986_bases
ATGGTCTTAATTAAGTCCACGCCACTAGAACTGACCCGCAGAAAAAACAGACCACCATCCCTATTCACCTACACCTACAC
CTACACATCTCAGGCTATACCTTCCTCATTATCATTTACCCAAGCTATAGAAACTGCCGAAATGGTGAGGCCTCAGCCAT
GGGATAAAAATCATTTATCCCGTTGGCCGTTGTTACATGTAGCGCTCATATTGCCTGATATCCGCCGCTATCAACAACAA
TGTGGAACCCTGCCCAACCTACTCAAACACATCACGGGTTGGCCACTCCCCCCTTTTGGTAGGATAGATAGTCAACATTT
ATCTGCTCAGGCCCGAGAGCCTCTCCCAGAGGGAGTAACATCGCCCATGCCCTGCTCTGGAGAACCGCTTTACTATGCGC
AGTGTCAACAAACGATCTGTGCTCCCCCACTGACAATGGCGACAAAATTAGTCCAGCGTTATCAAGAGGGTGCCCGCAAT
ATCTCTCACAGTAAAAGCGGCTCAGAAGGATATTCGTCACTCACTGACAATGAAGAATGGCAACCTTACGCTATCTATGA
AAAAGACGGTGAGTTCTCGGTCGGTATTGGGCTGGCGGCACTGATAACTGTCTATCCTAATTATGTTCACATACGTTACC
AGCAGCAAAATGCTCATGGCGATAGCTTTAGCGGCGAACAATTTCAAGAGCGTGTTTGGTTATCCTCCGACATCGTCGGT
AATATTTCATCCGCACTGGCAAGTATCCCGATTAAAGAGTGGCGAGCTTATGGTCTCAGCCAATTGGAATTGGTTCATCT
CTTCCATAACCCGGCGTCTCACGCGGCTCCCGGTACCGCACTACTGCAAATTTTCCTTCCACTGCATGAATATAGACTCA
ATCGCGGCAGCGCTATAATACGCAGTTTGCTTCCCTCTCACTTACCCCAACTGCTTACGATGCTGCAGCAATGTGACAGT
GACCAATATGACAACGCCCCCGCTATCAACAACTCATCTATCTATAAATCATCTAGTTGTGAACCATCTATTTATGAGTC
ACCAATTCATGAGCCATCTATTCATGAACAACCTGGCGATGAATATGATGAAAATAATCAACGTGACCATAATCAAGACA
GCCACCTGCAGACACAAGTAGAAAGAAGCGCCATCGAAATGCAGATACGCCAAACTGACCCTACTATTTTCTGTGATCGG
GTAGCAAAAACCGTTAATGAAATCAGGCAAGGTAAATATCAGAAAGCCATTTTATCGCGCCAGATACCGCTGCCAAATAA
TATTAATTTACTCGCAAGCTACCAACGTGGGCGCATAAATAACACCTCGGCACGCTCCTATGCTTTCCGGATGCAAGGAT
TTGAATTAATGGGCTTTAGCTCAAAGACTGCCGTGACTGTCTCAGCCAATGGCTGTCTGAGCACCCAACTTTTAACCGAT
ACACATGCACTGTCGTCAGACCAAACTCAATCGGTGCCACTTCATCATGAATTACGAATTAATACTGAAGATATCACTGA
ACATACCAGCTCAATCCTCTCTGTTGTTGCAACGCTAACACCAATCTGTGTACCAGGCTCAGTTGCCATTGTTCCGTATA
TGAAGGTGCTTACTTGCGGTAAGGTGCAAAATCTGGCCTCCTGTCTGCAAGGCCAGATACAAAAAGGCATCAGCCACTGG
CAAGCTATGCAATCCCTGTATCCTGTAGCTGCCGATATTCCTAAAGATCATCTGATGCAAGCAACTCTTCATGAACTGGG
ATCATGGGAGGCCTATAGCAGCAGCGTGCTAATGGTTGACAGCAATGGTGCATTGGATGCGACGCTAATTTCAGAGAGCC
TTTCCCGTAAGAATAAAAGATTTGGATTACGAGCCGGAACCGAAATCACCCATCAAGCAGACCCCCTACTCAAGCTAGAA
GAGACTCATGAGACGCTGATCGCGATTGCCCGTTATCTGGTGTTGCAAACAGCAATGACCGATTAA

Upstream 100 bases:

>100_bases
ACTAACTGGATTAACATAATAATAGTGATGATAGAAATTATCATTAAAATAAATAGAAAAAAATAATTAATCAAAATAAC
TATTACATAAGGATGATGTC

Downstream 100 bases:

>100_bases
CCCCGCTGCCGCCCATTACTACAAAACCAAACCATTATAAAACAAGAGGTCCATATTCGGTTGATGCTCACAATGCCACT
TTGTGAACATAAGGTTAACT

Product: chorismate binding-like protein

Products: NA

Alternate protein names: Mycobactin synthase protein I; Salicylate synthase mbtI [H]

Number of amino acids: Translated: 661; Mature: 661

Protein sequence:

>661_residues
MVLIKSTPLELTRRKNRPPSLFTYTYTYTSQAIPSSLSFTQAIETAEMVRPQPWDKNHLSRWPLLHVALILPDIRRYQQQ
CGTLPNLLKHITGWPLPPFGRIDSQHLSAQAREPLPEGVTSPMPCSGEPLYYAQCQQTICAPPLTMATKLVQRYQEGARN
ISHSKSGSEGYSSLTDNEEWQPYAIYEKDGEFSVGIGLAALITVYPNYVHIRYQQQNAHGDSFSGEQFQERVWLSSDIVG
NISSALASIPIKEWRAYGLSQLELVHLFHNPASHAAPGTALLQIFLPLHEYRLNRGSAIIRSLLPSHLPQLLTMLQQCDS
DQYDNAPAINNSSIYKSSSCEPSIYESPIHEPSIHEQPGDEYDENNQRDHNQDSHLQTQVERSAIEMQIRQTDPTIFCDR
VAKTVNEIRQGKYQKAILSRQIPLPNNINLLASYQRGRINNTSARSYAFRMQGFELMGFSSKTAVTVSANGCLSTQLLTD
THALSSDQTQSVPLHHELRINTEDITEHTSSILSVVATLTPICVPGSVAIVPYMKVLTCGKVQNLASCLQGQIQKGISHW
QAMQSLYPVAADIPKDHLMQATLHELGSWEAYSSSVLMVDSNGALDATLISESLSRKNKRFGLRAGTEITHQADPLLKLE
ETHETLIAIARYLVLQTAMTD

Sequences:

>Translated_661_residues
MVLIKSTPLELTRRKNRPPSLFTYTYTYTSQAIPSSLSFTQAIETAEMVRPQPWDKNHLSRWPLLHVALILPDIRRYQQQ
CGTLPNLLKHITGWPLPPFGRIDSQHLSAQAREPLPEGVTSPMPCSGEPLYYAQCQQTICAPPLTMATKLVQRYQEGARN
ISHSKSGSEGYSSLTDNEEWQPYAIYEKDGEFSVGIGLAALITVYPNYVHIRYQQQNAHGDSFSGEQFQERVWLSSDIVG
NISSALASIPIKEWRAYGLSQLELVHLFHNPASHAAPGTALLQIFLPLHEYRLNRGSAIIRSLLPSHLPQLLTMLQQCDS
DQYDNAPAINNSSIYKSSSCEPSIYESPIHEPSIHEQPGDEYDENNQRDHNQDSHLQTQVERSAIEMQIRQTDPTIFCDR
VAKTVNEIRQGKYQKAILSRQIPLPNNINLLASYQRGRINNTSARSYAFRMQGFELMGFSSKTAVTVSANGCLSTQLLTD
THALSSDQTQSVPLHHELRINTEDITEHTSSILSVVATLTPICVPGSVAIVPYMKVLTCGKVQNLASCLQGQIQKGISHW
QAMQSLYPVAADIPKDHLMQATLHELGSWEAYSSSVLMVDSNGALDATLISESLSRKNKRFGLRAGTEITHQADPLLKLE
ETHETLIAIARYLVLQTAMTD
>Mature_661_residues
MVLIKSTPLELTRRKNRPPSLFTYTYTYTSQAIPSSLSFTQAIETAEMVRPQPWDKNHLSRWPLLHVALILPDIRRYQQQ
CGTLPNLLKHITGWPLPPFGRIDSQHLSAQAREPLPEGVTSPMPCSGEPLYYAQCQQTICAPPLTMATKLVQRYQEGARN
ISHSKSGSEGYSSLTDNEEWQPYAIYEKDGEFSVGIGLAALITVYPNYVHIRYQQQNAHGDSFSGEQFQERVWLSSDIVG
NISSALASIPIKEWRAYGLSQLELVHLFHNPASHAAPGTALLQIFLPLHEYRLNRGSAIIRSLLPSHLPQLLTMLQQCDS
DQYDNAPAINNSSIYKSSSCEPSIYESPIHEPSIHEQPGDEYDENNQRDHNQDSHLQTQVERSAIEMQIRQTDPTIFCDR
VAKTVNEIRQGKYQKAILSRQIPLPNNINLLASYQRGRINNTSARSYAFRMQGFELMGFSSKTAVTVSANGCLSTQLLTD
THALSSDQTQSVPLHHELRINTEDITEHTSSILSVVATLTPICVPGSVAIVPYMKVLTCGKVQNLASCLQGQIQKGISHW
QAMQSLYPVAADIPKDHLMQATLHELGSWEAYSSSVLMVDSNGALDATLISESLSRKNKRFGLRAGTEITHQADPLLKLE
ETHETLIAIARYLVLQTAMTD

Specific function: Mediates the production of salicylate from chorismate via an isochorismate intermediate. Presents both isochorismate synthase and isochorismate-pyruvate lyase activities. Salycilate is the starter unit in the production of the virulence-conferring salicyl

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family. Salicylate synthase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: 700 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR015890
- InterPro:   IPR019996 [H]

Pfam domain/function: PF00425 Chorismate_bind [H]

EC number: =5.4.4.2 [H]

Molecular weight: Translated: 73851; Mature: 73851

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLIKSTPLELTRRKNRPPSLFTYTYTYTSQAIPSSLSFTQAIETAEMVRPQPWDKNHLS
CEEECCCCHHHHHCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
RWPLLHVALILPDIRRYQQQCGTLPNLLKHITGWPLPPFGRIDSQHLSAQAREPLPEGVT
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCC
SPMPCSGEPLYYAQCQQTICAPPLTMATKLVQRYQEGARNISHSKSGSEGYSSLTDNEEW
CCCCCCCCCEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
QPYAIYEKDGEFSVGIGLAALITVYPNYVHIRYQQQNAHGDSFSGEQFQERVWLSSDIVG
CCEEEEECCCCEEEHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
NISSALASIPIKEWRAYGLSQLELVHLFHNPASHAAPGTALLQIFLPLHEYRLNRGSAII
HHHHHHHHCCHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHH
RSLLPSHLPQLLTMLQQCDSDQYDNAPAINNSSIYKSSSCEPSIYESPIHEPSIHEQPGD
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCC
EYDENNQRDHNQDSHLQTQVERSAIEMQIRQTDPTIFCDRVAKTVNEIRQGKYQKAILSR
CCCCCCCCCCCCHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
QIPLPNNINLLASYQRGRINNTSARSYAFRMQGFELMGFSSKTAVTVSANGCLSTQLLTD
CCCCCCCCCEEEECCCCCCCCCCHHHEEHEECCEEEECCCCCEEEEEECCCCEEHHHHHH
THALSSDQTQSVPLHHELRINTEDITEHTSSILSVVATLTPICVPGSVAIVPYMKVLTCG
HHHCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
KVQNLASCLQGQIQKGISHWQAMQSLYPVAADIPKDHLMQATLHELGSWEAYSSSVLMVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEEE
SNGALDATLISESLSRKNKRFGLRAGTEITHQADPLLKLEETHETLIAIARYLVLQTAMT
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
D
C
>Mature Secondary Structure
MVLIKSTPLELTRRKNRPPSLFTYTYTYTSQAIPSSLSFTQAIETAEMVRPQPWDKNHLS
CEEECCCCHHHHHCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
RWPLLHVALILPDIRRYQQQCGTLPNLLKHITGWPLPPFGRIDSQHLSAQAREPLPEGVT
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCC
SPMPCSGEPLYYAQCQQTICAPPLTMATKLVQRYQEGARNISHSKSGSEGYSSLTDNEEW
CCCCCCCCCEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
QPYAIYEKDGEFSVGIGLAALITVYPNYVHIRYQQQNAHGDSFSGEQFQERVWLSSDIVG
CCEEEEECCCCEEEHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
NISSALASIPIKEWRAYGLSQLELVHLFHNPASHAAPGTALLQIFLPLHEYRLNRGSAII
HHHHHHHHCCHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHH
RSLLPSHLPQLLTMLQQCDSDQYDNAPAINNSSIYKSSSCEPSIYESPIHEPSIHEQPGD
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCC
EYDENNQRDHNQDSHLQTQVERSAIEMQIRQTDPTIFCDRVAKTVNEIRQGKYQKAILSR
CCCCCCCCCCCCHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
QIPLPNNINLLASYQRGRINNTSARSYAFRMQGFELMGFSSKTAVTVSANGCLSTQLLTD
CCCCCCCCCEEEECCCCCCCCCCHHHEEHEECCEEEECCCCCEEEEEECCCCEEHHHHHH
THALSSDQTQSVPLHHELRINTEDITEHTSSILSVVATLTPICVPGSVAIVPYMKVLTCG
HHHCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
KVQNLASCLQGQIQKGISHWQAMQSLYPVAADIPKDHLMQATLHELGSWEAYSSSVLMVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEEE
SNGALDATLISESLSRKNKRFGLRAGTEITHQADPLLKLEETHETLIAIARYLVLQTAMT
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
D
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA