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The map label for this gene is engD [H]

Identifier: 170024418

GI number: 170024418

Start: 2424807

End: 2425898

Strand: Direct

Name: engD [H]

Synonym: YPK_2187

Alternate gene names: 170024418

Gene position: 2424807-2425898 (Clockwise)

Preceding gene: 170024417

Following gene: 170024419

Centisome position: 51.71

GC content: 49.73

Gene sequence:

>1092_bases
ATGGGATTCAAATGCGGTATTGTGGGCCTGCCTAACGTCGGTAAATCCACCCTGTTCAACGCGTTGACACAAGCGGGTAT
TGAAGCAGCTAACTTCCCGTTCTGCACCATCGAGCCCAACACCGGTGTCGTGCCAATGCCGGACCCGCGTCTGGACCAAT
TGGCTGAGATTGTTAAGCCGCAACGTATCTTGCCAACAACCATGGAATTCGTGGATATCGCAGGGCTGGTAAAAGGGGCT
TCCAAAGGCGAAGGCTTGGGTAACCAGTTCCTGACCAATATCCGTGAAACCGAAGCAATTGGTCACGTGGTGCGTTGTTT
TGAAAATGACAACATCATCCATGTCGCCGGGAAAGTTGATCCAGCGGATGACATCGAAACAATCAATACCGAACTTGCCC
TCTCCGATTTAGAAACCTGCGAACGTGCCATTCATCGTGTCCAGAAAAAAGCCAAAGGCGGTGATAAAGACGCTAAAGCT
GAACTGGAAGCACTGGAGAAATGCCTGCCACATTTAGAGAATGCAGGCATGTTGCGCGCCTTGGATCTGACGGCTGAAGA
TAAAGCCGCTATCCGCTACCTGAGTTTTCTGACGCTGAAACCGACTATGTACATTGCCAACGTCAATGAAGATGGTTTCG
AAAACAACCCGTATCTGGATCAGGTGCGCGCTATTGCGGCGGCGGAAGGTTCGGTTGTCGTTGCGGTTTGTGCTGCGGTT
GAGTCTGATATTGCAGAAATGGAAGATGAAGATCGTGCTGAATTTATGGCCGAACTGGGCATTGAAGAGCCGGGGCTGAA
CCGTGTTATCCGTGCTGGTTATGAATTACTGAATCTACAAACCTACTTCACCGCGGGTGTCAAAGAAGTCCGTGCCTGGA
CCATCCCCGTGGGTGCCACGGCACCACAGGCCGCAGGTAAGATTCATACCGACTTCGAGAAAGGCTTTATCCGTGCACAA
ACTATCGCGTTTGATGACTTTATCACCTACAAAGGTGAACAAGGCGCGAAAGAAGCCGGAAAGATGCGTTCAGAAGGTAA
AGAATACATTGTTAAAGATGGTGATGTGATGAACTTCCTATTTAACGTCTAA

Upstream 100 bases:

>100_bases
ATAAATCATCATTATGTGTATAATGGCGGCATAAATTTTGATTACATCAATTCGCTAAACTTAACGGGTTGATTTTTAAG
TTATTTAAGGTGATATAAAC

Downstream 100 bases:

>100_bases
ATAAAATTTGTTGTCTCATGGGGTTTCGCTGAATCTCATGAGAATTGAAAAATGCTATAAAATCCACGCAATTGCGTGGA
TTTTTGTTTTCATATAAGGA

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MGFKCGIVGLPNVGKSTLFNALTQAGIEAANFPFCTIEPNTGVVPMPDPRLDQLAEIVKPQRILPTTMEFVDIAGLVKGA
SKGEGLGNQFLTNIRETEAIGHVVRCFENDNIIHVAGKVDPADDIETINTELALSDLETCERAIHRVQKKAKGGDKDAKA
ELEALEKCLPHLENAGMLRALDLTAEDKAAIRYLSFLTLKPTMYIANVNEDGFENNPYLDQVRAIAAAEGSVVVAVCAAV
ESDIAEMEDEDRAEFMAELGIEEPGLNRVIRAGYELLNLQTYFTAGVKEVRAWTIPVGATAPQAAGKIHTDFEKGFIRAQ
TIAFDDFITYKGEQGAKEAGKMRSEGKEYIVKDGDVMNFLFNV

Sequences:

>Translated_363_residues
MGFKCGIVGLPNVGKSTLFNALTQAGIEAANFPFCTIEPNTGVVPMPDPRLDQLAEIVKPQRILPTTMEFVDIAGLVKGA
SKGEGLGNQFLTNIRETEAIGHVVRCFENDNIIHVAGKVDPADDIETINTELALSDLETCERAIHRVQKKAKGGDKDAKA
ELEALEKCLPHLENAGMLRALDLTAEDKAAIRYLSFLTLKPTMYIANVNEDGFENNPYLDQVRAIAAAEGSVVVAVCAAV
ESDIAEMEDEDRAEFMAELGIEEPGLNRVIRAGYELLNLQTYFTAGVKEVRAWTIPVGATAPQAAGKIHTDFEKGFIRAQ
TIAFDDFITYKGEQGAKEAGKMRSEGKEYIVKDGDVMNFLFNV
>Mature_362_residues
GFKCGIVGLPNVGKSTLFNALTQAGIEAANFPFCTIEPNTGVVPMPDPRLDQLAEIVKPQRILPTTMEFVDIAGLVKGAS
KGEGLGNQFLTNIRETEAIGHVVRCFENDNIIHVAGKVDPADDIETINTELALSDLETCERAIHRVQKKAKGGDKDAKAE
LEALEKCLPHLENAGMLRALDLTAEDKAAIRYLSFLTLKPTMYIANVNEDGFENNPYLDQVRAIAAAEGSVVVAVCAAVE
SDIAEMEDEDRAEFMAELGIEEPGLNRVIRAGYELLNLQTYFTAGVKEVRAWTIPVGATAPQAAGKIHTDFEKGFIRAQT
IAFDDFITYKGEQGAKEAGKMRSEGKEYIVKDGDVMNFLFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=367, Percent_Identity=43.5967302452316, Blast_Score=296, Evalue=2e-80,
Organism=Homo sapiens, GI58761502, Length=226, Percent_Identity=36.7256637168142, Blast_Score=144, Evalue=2e-34,
Organism=Escherichia coli, GI1787454, Length=363, Percent_Identity=92.5619834710744, Blast_Score=697, Evalue=0.0,
Organism=Escherichia coli, GI1789574, Length=134, Percent_Identity=30.5970149253731, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17509631, Length=365, Percent_Identity=40.8219178082192, Blast_Score=285, Evalue=2e-77,
Organism=Saccharomyces cerevisiae, GI6319499, Length=368, Percent_Identity=39.4021739130435, Blast_Score=254, Evalue=1e-68,
Organism=Saccharomyces cerevisiae, GI6321773, Length=381, Percent_Identity=34.9081364829396, Blast_Score=201, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6321649, Length=145, Percent_Identity=38.6206896551724, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24640873, Length=366, Percent_Identity=43.4426229508197, Blast_Score=300, Evalue=8e-82,
Organism=Drosophila melanogaster, GI24640877, Length=366, Percent_Identity=43.4426229508197, Blast_Score=300, Evalue=8e-82,
Organism=Drosophila melanogaster, GI24640875, Length=366, Percent_Identity=43.4426229508197, Blast_Score=300, Evalue=8e-82,
Organism=Drosophila melanogaster, GI24640879, Length=328, Percent_Identity=40.8536585365854, Blast_Score=244, Evalue=8e-65,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39528; Mature: 39397

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFKCGIVGLPNVGKSTLFNALTQAGIEAANFPFCTIEPNTGVVPMPDPRLDQLAEIVKP
CCEEECEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHCC
QRILPTTMEFVDIAGLVKGASKGEGLGNQFLTNIRETEAIGHVVRCFENDNIIHVAGKVD
CCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
PADDIETINTELALSDLETCERAIHRVQKKAKGGDKDAKAELEALEKCLPHLENAGMLRA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEE
LDLTAEDKAAIRYLSFLTLKPTMYIANVNEDGFENNPYLDQVRAIAAAEGSVVVAVCAAV
EECCCCHHHHHHHHHHHEECCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEHHHHHH
ESDIAEMEDEDRAEFMAELGIEEPGLNRVIRAGYELLNLQTYFTAGVKEVRAWTIPVGAT
HHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCC
APQAAGKIHTDFEKGFIRAQTIAFDDFITYKGEQGAKEAGKMRSEGKEYIVKDGDVMNFL
CCHHCCCCCCHHHHCCEEEEEEEEHHHHEECCCCCHHHHHHHHHCCCCEEECCCHHHHHH
FNV
HCC
>Mature Secondary Structure 
GFKCGIVGLPNVGKSTLFNALTQAGIEAANFPFCTIEPNTGVVPMPDPRLDQLAEIVKP
CEEECEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHCC
QRILPTTMEFVDIAGLVKGASKGEGLGNQFLTNIRETEAIGHVVRCFENDNIIHVAGKVD
CCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
PADDIETINTELALSDLETCERAIHRVQKKAKGGDKDAKAELEALEKCLPHLENAGMLRA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEE
LDLTAEDKAAIRYLSFLTLKPTMYIANVNEDGFENNPYLDQVRAIAAAEGSVVVAVCAAV
EECCCCHHHHHHHHHHHEECCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEHHHHHH
ESDIAEMEDEDRAEFMAELGIEEPGLNRVIRAGYELLNLQTYFTAGVKEVRAWTIPVGAT
HHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCC
APQAAGKIHTDFEKGFIRAQTIAFDDFITYKGEQGAKEAGKMRSEGKEYIVKDGDVMNFL
CCHHCCCCCCHHHHCCEEEEEEEEHHHHEECCCCCHHHHHHHHHCCCCEEECCCHHHHHH
FNV
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]