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The map label for this gene is minC [H]

Identifier: 170024355

GI number: 170024355

Start: 2351965

End: 2352651

Strand: Direct

Name: minC [H]

Synonym: YPK_2121

Alternate gene names: 170024355

Gene position: 2351965-2352651 (Clockwise)

Preceding gene: 170024350

Following gene: 170024356

Centisome position: 50.15

GC content: 47.6

Gene sequence:

>687_bases
ATGTCACAATCGCCAATCGAGTTAAAAGGCAGTAGTTTTACCCTATCGGTCGTTCATTTACATGATTCGCGGCCAGAGGT
AATCCGTCAGGCATTGCAGGAAAAGGTGGATCAAGCCCCCGCATTTCTGAAAAACGCCCCTGTTGTGATTAACGTTGCAA
CGTTACCTAACGGTGCTAACTGGAAAGATCTTCAACAGGCTGTCACTTCAGCAGGTCTGCGTATTGTCGGCATTAGCGGT
TGTCAGGATGAGCGTCAGAAACGAGCAATTGCACGTGCAGGGTTGCCATTATTGAGTGAGGGTAAAGGCCAAAAACTGGC
TCCAGAGCCGGTCATCAGTCCGCCGGAAAACGTTCCCACCCAAACGCGTATCATCAACACCCCGGTCCGCTCAGGCCAAC
AGATTTATGCCCGTAATTGCGATTTGATTGTTATTAGCAGTGTCAGTGCCGGTGCTGAATTAATTGCCGATGGTAATATC
CATATTTATGGAATGATGCGAGGCCGAGCACTAGCAGGAGCATCCGGTGATGCTAAGTGCCAGATTTTTTGTACACATCT
GGGTGCTGAACTTGTCTCTATCGCCGGGCAGTACTGGTTGAGTGATCAGATACCGCTTGAGTATTTTGGTCAAGCTGCAC
GTCTGTATCTGCAGGATAATACATTAACTATACAACCTTTAAATTAA

Upstream 100 bases:

>100_bases
TTTCTTTTTATATTCCCTATAACATGCTTAGGAACATCCGAATATGGTTCCCCGCATGGTATTCTGGGGATTAAACGTAG
CTGAAACTGAGTCAGGATAG

Downstream 100 bases:

>100_bases
GCCCTTTGACAAGGAATCCATTTCATGGCACGCATTATTGTTGTTACATCGGGTAAAGGGGGCGTTGGCAAGACCACATC
AAGCGCGGCTATTGCTACCG

Product: septum formation inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MSQSPIELKGSSFTLSVVHLHDSRPEVIRQALQEKVDQAPAFLKNAPVVINVATLPNGANWKDLQQAVTSAGLRIVGISG
CQDERQKRAIARAGLPLLSEGKGQKLAPEPVISPPENVPTQTRIINTPVRSGQQIYARNCDLIVISSVSAGAELIADGNI
HIYGMMRGRALAGASGDAKCQIFCTHLGAELVSIAGQYWLSDQIPLEYFGQAARLYLQDNTLTIQPLN

Sequences:

>Translated_228_residues
MSQSPIELKGSSFTLSVVHLHDSRPEVIRQALQEKVDQAPAFLKNAPVVINVATLPNGANWKDLQQAVTSAGLRIVGISG
CQDERQKRAIARAGLPLLSEGKGQKLAPEPVISPPENVPTQTRIINTPVRSGQQIYARNCDLIVISSVSAGAELIADGNI
HIYGMMRGRALAGASGDAKCQIFCTHLGAELVSIAGQYWLSDQIPLEYFGQAARLYLQDNTLTIQPLN
>Mature_227_residues
SQSPIELKGSSFTLSVVHLHDSRPEVIRQALQEKVDQAPAFLKNAPVVINVATLPNGANWKDLQQAVTSAGLRIVGISGC
QDERQKRAIARAGLPLLSEGKGQKLAPEPVISPPENVPTQTRIINTPVRSGQQIYARNCDLIVISSVSAGAELIADGNIH
IYGMMRGRALAGASGDAKCQIFCTHLGAELVSIAGQYWLSDQIPLEYFGQAARLYLQDNTLTIQPLN

Specific function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize ftsZ filaments that have formed before they mature into polar Z rings. Prevents ftsZ polymerization [H]

COG id: COG0850

COG function: function code D; Septum formation inhibitor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minC family [H]

Homologues:

Organism=Escherichia coli, GI1787424, Length=231, Percent_Identity=64.9350649350649, Blast_Score=313, Evalue=4e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016098
- InterPro:   IPR013033
- InterPro:   IPR007874
- InterPro:   IPR005526 [H]

Pfam domain/function: PF03775 MinC_C; PF05209 MinC_N [H]

EC number: NA

Molecular weight: Translated: 24546; Mature: 24415

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSPIELKGSSFTLSVVHLHDSRPEVIRQALQEKVDQAPAFLKNAPVVINVATLPNGAN
CCCCCCEECCCEEEEEEEEEECCCHHHHHHHHHHHHHHCHHHHCCCCEEEEEEECCCCCC
WKDLQQAVTSAGLRIVGISGCQDERQKRAIARAGLPLLSEGKGQKLAPEPVISPPENVPT
HHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
QTRIINTPVRSGQQIYARNCDLIVISSVSAGAELIADGNIHIYGMMRGRALAGASGDAKC
CEEEEECCCCCCCEEEECCCCEEEEECCCCCCEEEECCCEEEEEEEECCEEECCCCCCEE
QIFCTHLGAELVSIAGQYWLSDQIPLEYFGQAARLYLQDNTLTIQPLN
EEEEEHHHHHHHHHHHHHHCCCCCCHHHCCCEEEEEEECCEEEEEECC
>Mature Secondary Structure 
SQSPIELKGSSFTLSVVHLHDSRPEVIRQALQEKVDQAPAFLKNAPVVINVATLPNGAN
CCCCCEECCCEEEEEEEEEECCCHHHHHHHHHHHHHHCHHHHCCCCEEEEEEECCCCCC
WKDLQQAVTSAGLRIVGISGCQDERQKRAIARAGLPLLSEGKGQKLAPEPVISPPENVPT
HHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
QTRIINTPVRSGQQIYARNCDLIVISSVSAGAELIADGNIHIYGMMRGRALAGASGDAKC
CEEEEECCCCCCCEEEECCCCEEEEECCCCCCEEEECCCEEEEEEEECCEEECCCCCCEE
QIFCTHLGAELVSIAGQYWLSDQIPLEYFGQAARLYLQDNTLTIQPLN
EEEEEHHHHHHHHHHHHHHCCCCCCHHHCCCEEEEEEECCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA