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The map label for this gene is acoR [H]

Identifier: 170024212

GI number: 170024212

Start: 2194759

End: 2196603

Strand: Direct

Name: acoR [H]

Synonym: YPK_1975

Alternate gene names: 170024212

Gene position: 2194759-2196603 (Clockwise)

Preceding gene: 170024210

Following gene: 170024213

Centisome position: 46.8

GC content: 51.22

Gene sequence:

>1845_bases
ATGTGTAGCGAAGGTGTGAAATTACCAATGCAGGGAAATTTATCAGCCGTCAGCACGCCCACTACGGCGTGCAATCAACG
ACTCCGTGACTCTTGGCTGCGTAGCCAACTCTACGGTTTAGATCGCATGTCCGACGATGTTCCCCGTATTGAGCAGGGAG
AACTGGCCGACTTGCTGGTCAGTCACGCCGTATTACAGCAATTTTCTCAGCCAACAGTGAAAGCGCTGGCTGAGAAAATT
GCCGATAAGCAATCGGTAGTGGTCCTCGCCGATGCCAGTGGGTTGGTATTGAATACCTTCGGCGATATACAGGCTCTACA
AAAAGCACAACAGTTTGCCCTGACGCCCGGTAATCTATGGAGTGAATGCAGCCGAGGAACGAATGCCATTGGTACTGCCC
TGGCGATTGATGATAGCTGCGAAATCTATGGACATCAGCATTATCTTATTAACAATCAGGGGCTTTACTGCGCGGCTATG
CCACTGCAAGCGCCTAACGGACAGATTGCCGGTGTGCTGGATATATCGGGTCCGGCGTATCACTCCCATCCCCACACACT
GGCATGGATAAAAAACGCGGCGAAACAAATTGAGTATTTATGGGTGAAACAGAGCCTGCATCCAGATCAGTGGCTGATGA
GTCTGCATCCACAAATACAAGGCATTGATAATATTGAAGAGCTACTACTGGTGTTCTCTGATAACACTCTGATGGCAGCT
AACCGTCTGGCGATGCACGAGTTGGCGTTGGGGGCCGACCAGTTTGGTGCCCTAACCTTCCAGCAACTTTTTCCGCAAAG
TAAGCAAGTTGCCAATCAGGTGCCGCACCCTTTAATGGCTCGCAATCAACAACGTTATTTCTTTCGCCTACGGGCGCCAG
CACGAAGCCACTTCCCTGCAATAATACACGTTCCCACAACACACGTTCCCACAACATCGGTAACTTCGCCTGACTTATCC
TTCTCACTGCGCGATGACGATAAGAAAATGGTGCGATTACTCAATGCTGGCGTCTCGCTTTGTATAAATGGTGAGACTGG
CAGTGGTAAGGAGTATGTTAGCCGGGCTTTACATCAGCAGAGCCGGTGGCGGCAAGGTAAGTTTGTTGTTATCAACTGCG
CTGCCATACCAGAGTCTCTGATTGAATCAGAACTCTTCGGATACCAACCGGGTGCATTTACGGGGGCCAGCAAAAATGGC
TATATTGGCAAAATTCGGGAGGCCGACGGTGGCGTACTGTTTCTGGATGAAATAGGCGATATGCCGTTATCGCTACAAAC
CCGCTTACTCCGAGTATTGCAAGAAAAAGAGGTGACGCCGCTGGGCTCTAGCCGTAGTTGGCCAGTCAATTTTGCGGTGG
TCTGTGCTACGCATCGGGATCTTCCCCAGTTGGTCGCGGAGGGCGGGTTCCGTGAAGACCTCCTCTACCGATTGCAAGAG
TTCTCTCTAACCATTCCGCCACTGCGTGAATGGCCCGCGCTGCCCGCCTTTATTTTACAGCTATGGAGGGCGTTGGGCGG
TGAGCAACGGGGCATTCTCTTTACGCCAGCACTGCTTGATACGCTGGCGAAGCATCCTTGGCCGGGTAATGTGCGTCAAC
TGCAAAGTTTACTGAAGGTATTATTCGCCCTGGCGGATGACGATGAGGTTCTTGATTGCGAGACACTGCCTGACAACTTC
CGAGGTGAGAATAGTGAACCGTACCCCGCGCTGCAACAGCATGACAAGCAGTTTATTGAGAAAACACTGCAATATTTTAA
CGGTAACATCAGTAAAACTGCCAAGGCTTTGGGCATAGCACGCAGTACGCTATACCGCCGTGCCGCGCGAGAAAAACGCC
AGTAA

Upstream 100 bases:

>100_bases
TGATAAATTAATTTTGTTTTTAGAGATAAATAGAGAAGGGGTTAATATTTGCGTTGCAAATCGCAACATTAAAATCATTA
TTGAGCCACAATAATGATAC

Downstream 100 bases:

>100_bases
AATAGTATATTCCCTAGCGGCAAGCCGATACCTAAGTGATGGATTCCACTCTGACTCAGAATATGTTAATGATATCAATT
AGATTATTGGTAACAACAAA

Product: Fis family GAF modulated sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 614; Mature: 614

Protein sequence:

>614_residues
MCSEGVKLPMQGNLSAVSTPTTACNQRLRDSWLRSQLYGLDRMSDDVPRIEQGELADLLVSHAVLQQFSQPTVKALAEKI
ADKQSVVVLADASGLVLNTFGDIQALQKAQQFALTPGNLWSECSRGTNAIGTALAIDDSCEIYGHQHYLINNQGLYCAAM
PLQAPNGQIAGVLDISGPAYHSHPHTLAWIKNAAKQIEYLWVKQSLHPDQWLMSLHPQIQGIDNIEELLLVFSDNTLMAA
NRLAMHELALGADQFGALTFQQLFPQSKQVANQVPHPLMARNQQRYFFRLRAPARSHFPAIIHVPTTHVPTTSVTSPDLS
FSLRDDDKKMVRLLNAGVSLCINGETGSGKEYVSRALHQQSRWRQGKFVVINCAAIPESLIESELFGYQPGAFTGASKNG
YIGKIREADGGVLFLDEIGDMPLSLQTRLLRVLQEKEVTPLGSSRSWPVNFAVVCATHRDLPQLVAEGGFREDLLYRLQE
FSLTIPPLREWPALPAFILQLWRALGGEQRGILFTPALLDTLAKHPWPGNVRQLQSLLKVLFALADDDEVLDCETLPDNF
RGENSEPYPALQQHDKQFIEKTLQYFNGNISKTAKALGIARSTLYRRAAREKRQ

Sequences:

>Translated_614_residues
MCSEGVKLPMQGNLSAVSTPTTACNQRLRDSWLRSQLYGLDRMSDDVPRIEQGELADLLVSHAVLQQFSQPTVKALAEKI
ADKQSVVVLADASGLVLNTFGDIQALQKAQQFALTPGNLWSECSRGTNAIGTALAIDDSCEIYGHQHYLINNQGLYCAAM
PLQAPNGQIAGVLDISGPAYHSHPHTLAWIKNAAKQIEYLWVKQSLHPDQWLMSLHPQIQGIDNIEELLLVFSDNTLMAA
NRLAMHELALGADQFGALTFQQLFPQSKQVANQVPHPLMARNQQRYFFRLRAPARSHFPAIIHVPTTHVPTTSVTSPDLS
FSLRDDDKKMVRLLNAGVSLCINGETGSGKEYVSRALHQQSRWRQGKFVVINCAAIPESLIESELFGYQPGAFTGASKNG
YIGKIREADGGVLFLDEIGDMPLSLQTRLLRVLQEKEVTPLGSSRSWPVNFAVVCATHRDLPQLVAEGGFREDLLYRLQE
FSLTIPPLREWPALPAFILQLWRALGGEQRGILFTPALLDTLAKHPWPGNVRQLQSLLKVLFALADDDEVLDCETLPDNF
RGENSEPYPALQQHDKQFIEKTLQYFNGNISKTAKALGIARSTLYRRAAREKRQ
>Mature_614_residues
MCSEGVKLPMQGNLSAVSTPTTACNQRLRDSWLRSQLYGLDRMSDDVPRIEQGELADLLVSHAVLQQFSQPTVKALAEKI
ADKQSVVVLADASGLVLNTFGDIQALQKAQQFALTPGNLWSECSRGTNAIGTALAIDDSCEIYGHQHYLINNQGLYCAAM
PLQAPNGQIAGVLDISGPAYHSHPHTLAWIKNAAKQIEYLWVKQSLHPDQWLMSLHPQIQGIDNIEELLLVFSDNTLMAA
NRLAMHELALGADQFGALTFQQLFPQSKQVANQVPHPLMARNQQRYFFRLRAPARSHFPAIIHVPTTHVPTTSVTSPDLS
FSLRDDDKKMVRLLNAGVSLCINGETGSGKEYVSRALHQQSRWRQGKFVVINCAAIPESLIESELFGYQPGAFTGASKNG
YIGKIREADGGVLFLDEIGDMPLSLQTRLLRVLQEKEVTPLGSSRSWPVNFAVVCATHRDLPQLVAEGGFREDLLYRLQE
FSLTIPPLREWPALPAFILQLWRALGGEQRGILFTPALLDTLAKHPWPGNVRQLQSLLKVLFALADDDEVLDCETLPDNF
RGENSEPYPALQQHDKQFIEKTLQYFNGNISKTAKALGIARSTLYRRAAREKRQ

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=311, Percent_Identity=42.1221864951768, Blast_Score=229, Evalue=4e-61,
Organism=Escherichia coli, GI1788905, Length=296, Percent_Identity=40.8783783783784, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI87082117, Length=293, Percent_Identity=41.9795221843003, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1790437, Length=289, Percent_Identity=39.7923875432526, Blast_Score=192, Evalue=6e-50,
Organism=Escherichia coli, GI1786524, Length=298, Percent_Identity=39.9328859060403, Blast_Score=192, Evalue=6e-50,
Organism=Escherichia coli, GI1789087, Length=286, Percent_Identity=43.006993006993, Blast_Score=192, Evalue=8e-50,
Organism=Escherichia coli, GI1788550, Length=301, Percent_Identity=37.8737541528239, Blast_Score=190, Evalue=3e-49,
Organism=Escherichia coli, GI1790299, Length=332, Percent_Identity=36.7469879518072, Blast_Score=189, Evalue=4e-49,
Organism=Escherichia coli, GI87082152, Length=233, Percent_Identity=41.6309012875536, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI87081872, Length=290, Percent_Identity=36.2068965517241, Blast_Score=158, Evalue=8e-40,
Organism=Escherichia coli, GI1787583, Length=200, Percent_Identity=38.5, Blast_Score=143, Evalue=4e-35,
Organism=Escherichia coli, GI87081858, Length=640, Percent_Identity=25, Blast_Score=140, Evalue=3e-34,
Organism=Escherichia coli, GI1789828, Length=154, Percent_Identity=42.8571428571429, Blast_Score=124, Evalue=2e-29,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 68254; Mature: 68254

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCSEGVKLPMQGNLSAVSTPTTACNQRLRDSWLRSQLYGLDRMSDDVPRIEQGELADLLV
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHH
SHAVLQQFSQPTVKALAEKIADKQSVVVLADASGLVLNTFGDIQALQKAQQFALTPGNLW
HHHHHHHHCCHHHHHHHHHHCCCCCEEEEECCCCEEEECHHHHHHHHHHHHHCCCCCHHH
SECSRGTNAIGTALAIDDSCEIYGHQHYLINNQGLYCAAMPLQAPNGQIAGVLDISGPAY
HHHHCCCCHHCEEEEECCCCEEEECEEEEECCCCEEEEEECCCCCCCCEEEEEECCCCCC
HSHPHTLAWIKNAAKQIEYLWVKQSLHPDQWLMSLHPQIQGIDNIEELLLVFSDNTLMAA
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHEEECCCCEEHH
NRLAMHELALGADQFGALTFQQLFPQSKQVANQVPHPLMARNQQRYFFRLRAPARSHFPA
HHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHCCCHHHHCCCCEEEEEEECCCCCCCCE
IIHVPTTHVPTTSVTSPDLSFSLRDDDKKMVRLLNAGVSLCINGETGSGKEYVSRALHQQ
EEECCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHH
SRWRQGKFVVINCAAIPESLIESELFGYQPGAFTGASKNGYIGKIREADGGVLFLDEIGD
HHCCCCCEEEEECHHCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCC
MPLSLQTRLLRVLQEKEVTPLGSSRSWPVNFAVVCATHRDLPQLVAEGGFREDLLYRLQE
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHCCCCHHHHHHHHHH
FSLTIPPLREWPALPAFILQLWRALGGEQRGILFTPALLDTLAKHPWPGNVRQLQSLLKV
HCCCCCCHHHCCCCHHHHHHHHHHHCCCCCCEEECHHHHHHHHCCCCCCCHHHHHHHHHH
LFALADDDEVLDCETLPDNFRGENSEPYPALQQHDKQFIEKTLQYFNGNISKTAKALGIA
HHHHCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
RSTLYRRAAREKRQ
HHHHHHHHHHHHCC
>Mature Secondary Structure
MCSEGVKLPMQGNLSAVSTPTTACNQRLRDSWLRSQLYGLDRMSDDVPRIEQGELADLLV
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHH
SHAVLQQFSQPTVKALAEKIADKQSVVVLADASGLVLNTFGDIQALQKAQQFALTPGNLW
HHHHHHHHCCHHHHHHHHHHCCCCCEEEEECCCCEEEECHHHHHHHHHHHHHCCCCCHHH
SECSRGTNAIGTALAIDDSCEIYGHQHYLINNQGLYCAAMPLQAPNGQIAGVLDISGPAY
HHHHCCCCHHCEEEEECCCCEEEECEEEEECCCCEEEEEECCCCCCCCEEEEEECCCCCC
HSHPHTLAWIKNAAKQIEYLWVKQSLHPDQWLMSLHPQIQGIDNIEELLLVFSDNTLMAA
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHEEECCCCEEHH
NRLAMHELALGADQFGALTFQQLFPQSKQVANQVPHPLMARNQQRYFFRLRAPARSHFPA
HHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHCCCHHHHCCCCEEEEEEECCCCCCCCE
IIHVPTTHVPTTSVTSPDLSFSLRDDDKKMVRLLNAGVSLCINGETGSGKEYVSRALHQQ
EEECCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHH
SRWRQGKFVVINCAAIPESLIESELFGYQPGAFTGASKNGYIGKIREADGGVLFLDEIGD
HHCCCCCEEEEECHHCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCC
MPLSLQTRLLRVLQEKEVTPLGSSRSWPVNFAVVCATHRDLPQLVAEGGFREDLLYRLQE
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHCCCCHHHHHHHHHH
FSLTIPPLREWPALPAFILQLWRALGGEQRGILFTPALLDTLAKHPWPGNVRQLQSLLKV
HCCCCCCHHHCCCCHHHHHHHHHHHCCCCCCEEECHHHHHHHHCCCCCCCHHHHHHHHHH
LFALADDDEVLDCETLPDNFRGENSEPYPALQQHDKQFIEKTLQYFNGNISKTAKALGIA
HHHHCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
RSTLYRRAAREKRQ
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]