Click here to switch to the map view.

The map label for this gene is pdxH [H]

Identifier: 170024119

GI number: 170024119

Start: 2085488

End: 2086210

Strand: Direct

Name: pdxH [H]

Synonym: YPK_1880

Alternate gene names: 170024119

Gene position: 2085488-2086210 (Clockwise)

Preceding gene: 170024118

Following gene: 170024120

Centisome position: 44.47

GC content: 48.69

Gene sequence:

>723_bases
ATGATTGTGATTCTGTGGCGGCGAGGGCAGAATGATAACCACAGCTTTCCTGCGCGTTACAGAGTTTATATGACTGAGAA
TAATGAGTTTGATGTTGCAGACTTGCGTCGTGAGTATATTCGGGGTGGTCTGCGCCGCAGTGATTTAACTGAAAACCCTT
TAGAATTATTCGAGCGCTGGTTAAAACAGGCATGTGAAGCTCGCTTGCCCGATCCGACCGCAATGTGTGTGGCTACCGTT
GATATCAATGGTCAGCCCTACCAGCGTATCGTGCTCTTGAAACATTATGATGATCAGGGCTTAGTGTTTTACACTAATTT
AGGTAGCCGCAAAGCACAACAATTGGCTGAGAACCCGCATATCAGCCTATTGTTTCCCTGGCATATGCTGGATCGGCAAG
TGATTTTCCTCGGCAAGGCGGAGCGCCTCTCCACATTGGAAGTCCTGAAGTATTTCCATTCCCGTCCGAAAGACAGTCAA
ATTGGTGCTTGGGTTTCCCAGCAATCCTCACGTATTTCTGCTCGTGGTGTCCTGGAAAGCAAATTTCTTGAGCTGAAACA
AAAATTCCAGCAGGGTGACGTACCGCTGCCCAGTTTTTGGGGCGGGTTTCGCGTCAAATTCGATTCCGTTGAGTTTTGGC
AGGGGGGGGAACATCGCCTTCATGACCGTTTTATCTATCAACGGGAAGCCGACGCGTGGAAAATTGACCGTTTAGCCCCT
TAG

Upstream 100 bases:

>100_bases
TTTCTGGTCGAAGGGTGATAGCGCATTTATTGAGCGCGAGGAGAAAGTCATCATTAATGATTGTGTTTTGATCAAGTAAT
CTCGTCGTCGTAGGCTCTGG

Downstream 100 bases:

>100_bases
GACGATGAAATATTGTGGTTAAACTGTAACGGGCGCTTTATTCTATATGCCGATTAAACGCCTATGCTGATTAAAAGCCT
ATGCCGATTGAAAATATATG

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase [H]

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MIVILWRRGQNDNHSFPARYRVYMTENNEFDVADLRREYIRGGLRRSDLTENPLELFERWLKQACEARLPDPTAMCVATV
DINGQPYQRIVLLKHYDDQGLVFYTNLGSRKAQQLAENPHISLLFPWHMLDRQVIFLGKAERLSTLEVLKYFHSRPKDSQ
IGAWVSQQSSRISARGVLESKFLELKQKFQQGDVPLPSFWGGFRVKFDSVEFWQGGEHRLHDRFIYQREADAWKIDRLAP

Sequences:

>Translated_240_residues
MIVILWRRGQNDNHSFPARYRVYMTENNEFDVADLRREYIRGGLRRSDLTENPLELFERWLKQACEARLPDPTAMCVATV
DINGQPYQRIVLLKHYDDQGLVFYTNLGSRKAQQLAENPHISLLFPWHMLDRQVIFLGKAERLSTLEVLKYFHSRPKDSQ
IGAWVSQQSSRISARGVLESKFLELKQKFQQGDVPLPSFWGGFRVKFDSVEFWQGGEHRLHDRFIYQREADAWKIDRLAP
>Mature_240_residues
MIVILWRRGQNDNHSFPARYRVYMTENNEFDVADLRREYIRGGLRRSDLTENPLELFERWLKQACEARLPDPTAMCVATV
DINGQPYQRIVLLKHYDDQGLVFYTNLGSRKAQQLAENPHISLLFPWHMLDRQVIFLGKAERLSTLEVLKYFHSRPKDSQ
IGAWVSQQSSRISARGVLESKFLELKQKFQQGDVPLPSFWGGFRVKFDSVEFWQGGEHRLHDRFIYQREADAWKIDRLAP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) [H]

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922498, Length=234, Percent_Identity=38.4615384615385, Blast_Score=157, Evalue=6e-39,
Organism=Escherichia coli, GI1787926, Length=218, Percent_Identity=78.4403669724771, Blast_Score=367, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI17553712, Length=230, Percent_Identity=36.0869565217391, Blast_Score=142, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6319509, Length=209, Percent_Identity=39.2344497607655, Blast_Score=150, Evalue=2e-37,
Organism=Drosophila melanogaster, GI45551845, Length=208, Percent_Identity=40.3846153846154, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24644901, Length=208, Percent_Identity=40.3846153846154, Blast_Score=149, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24644903, Length=178, Percent_Identity=30.8988764044944, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase [H]

EC number: =1.4.3.5 [H]

Molecular weight: Translated: 28270; Mature: 28270

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: PS01064 PYRIDOX_OXIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVILWRRGQNDNHSFPARYRVYMTENNEFDVADLRREYIRGGLRRSDLTENPLELFERW
CEEEEEECCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
LKQACEARLPDPTAMCVATVDINGQPYQRIVLLKHYDDQGLVFYTNLGSRKAQQLAENPH
HHHHHHCCCCCCCEEEEEEEECCCCCCEEEEEEEEECCCCEEEEECCCCHHHHHHHCCCC
ISLLFPWHMLDRQVIFLGKAERLSTLEVLKYFHSRPKDSQIGAWVSQQSSRISARGVLES
EEEEECHHHHCCEEEEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHH
KFLELKQKFQQGDVPLPSFWGGFRVKFDSVEFWQGGEHRLHDRFIYQREADAWKIDRLAP
HHHHHHHHHHHCCCCCCCCCCCEEEEECCEEECCCCCHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MIVILWRRGQNDNHSFPARYRVYMTENNEFDVADLRREYIRGGLRRSDLTENPLELFERW
CEEEEEECCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
LKQACEARLPDPTAMCVATVDINGQPYQRIVLLKHYDDQGLVFYTNLGSRKAQQLAENPH
HHHHHHCCCCCCCEEEEEEEECCCCCCEEEEEEEEECCCCEEEEECCCCHHHHHHHCCCC
ISLLFPWHMLDRQVIFLGKAERLSTLEVLKYFHSRPKDSQIGAWVSQQSSRISARGVLES
EEEEECHHHHCCEEEEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHH
KFLELKQKFQQGDVPLPSFWGGFRVKFDSVEFWQGGEHRLHDRFIYQREADAWKIDRLAP
HHHHHHHHHHHCCCCCCCCCCCEEEEECCEEECCCCCHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA