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The map label for this gene is iscR [H]

Identifier: 170023521

GI number: 170023521

Start: 1403105

End: 1403662

Strand: Direct

Name: iscR [H]

Synonym: YPK_1275

Alternate gene names: 170023521

Gene position: 1403105-1403662 (Clockwise)

Preceding gene: 170023520

Following gene: 170023522

Centisome position: 29.92

GC content: 50.36

Gene sequence:

>558_bases
TTGACTAAAACACTCAAGAATGTCAAAATTCTGTTTCGTGTTCACCAACAGGTAACTTTAGCTATGAGACTGACATCCAA
AGGCCGCTATGCCGTAACCGCCATGCTTGATGTGGCATTACATTCCCAGGACGGGCCCGTTCCTCTGGCAGATATTTCGG
AACGTCAGGGGATCTCGTTATCCTATCTGGAACAACTTTTTTCACGCCTACGTAAAAATGGCTTAGTCGCCAGCGTACGC
GGCCCAGGCGGTGGTTATCTGCTGGGCAAAGATGCATCAGCAATCGCGGTTGGCGCGGTTATCACTGCCGTTGACGAATC
CGTTGATGCAACCCGTTGTCAGGGTAAAGAAGGCTGTCAGGGCGGAAATCGCTGCCTGACACATACCCTGTGGCGTGATT
TGAGCGAGCGTATCAGCAGCTTCCTCAACAATATTACATTGGCAGAACTGGTTAATAACCAAGATATCCTAGAGGTAGCG
GATCGTCAGAATAACGATACGCGCCGCACGGCTAATGGCCGACCGCAAGAGACGATTAACGTCAATCTGCGCGCATAA

Upstream 100 bases:

>100_bases
AGGATTAATGTCTTATATCAATTGGTTATAATTAATTCTAATTGATACTATCGAGCGTAAGTATGGTGATAATAGTTGAG
TGAATTACTAGGTTAAATAG

Downstream 100 bases:

>100_bases
GCAGAATTTGCGGAATTTTACGTTTTGGAAGTGATGTACGGAGCATAAGAGCAATGACCGAATCAAAAGTAAAGACACCG
ATCTATCTGGATTATGCAGC

Product: DNA-binding transcriptional regulator IscR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MTKTLKNVKILFRVHQQVTLAMRLTSKGRYAVTAMLDVALHSQDGPVPLADISERQGISLSYLEQLFSRLRKNGLVASVR
GPGGGYLLGKDASAIAVGAVITAVDESVDATRCQGKEGCQGGNRCLTHTLWRDLSERISSFLNNITLAELVNNQDILEVA
DRQNNDTRRTANGRPQETINVNLRA

Sequences:

>Translated_185_residues
MTKTLKNVKILFRVHQQVTLAMRLTSKGRYAVTAMLDVALHSQDGPVPLADISERQGISLSYLEQLFSRLRKNGLVASVR
GPGGGYLLGKDASAIAVGAVITAVDESVDATRCQGKEGCQGGNRCLTHTLWRDLSERISSFLNNITLAELVNNQDILEVA
DRQNNDTRRTANGRPQETINVNLRA
>Mature_184_residues
TKTLKNVKILFRVHQQVTLAMRLTSKGRYAVTAMLDVALHSQDGPVPLADISERQGISLSYLEQLFSRLRKNGLVASVRG
PGGGYLLGKDASAIAVGAVITAVDESVDATRCQGKEGCQGGNRCLTHTLWRDLSERISSFLNNITLAELVNNQDILEVAD
RQNNDTRRTANGRPQETINVNLRA

Specific function: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins [H]

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=165, Percent_Identity=79.3939393939394, Blast_Score=237, Evalue=3e-64,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010242
- InterPro:   IPR000944
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 20216; Mature: 20085

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: PS01332 UPF0074

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTLKNVKILFRVHQQVTLAMRLTSKGRYAVTAMLDVALHSQDGPVPLADISERQGISL
CCCCHHHHHHHHHHHHHHHEEEEECCCCCEEHHHHHHHHHCCCCCCCCHHCCCCCCCCCH
SYLEQLFSRLRKNGLVASVRGPGGGYLLGKDASAIAVGAVITAVDESVDATRCQGKEGCQ
HHHHHHHHHHHHCCCEEEEECCCCCEEECCCCCHHHHHHHHHHHHCCCCHHHCCCCCCCC
GGNRCLTHTLWRDLSERISSFLNNITLAELVNNQDILEVADRQNNDTRRTANGRPQETIN
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCEEE
VNLRA
EEEEC
>Mature Secondary Structure 
TKTLKNVKILFRVHQQVTLAMRLTSKGRYAVTAMLDVALHSQDGPVPLADISERQGISL
CCCHHHHHHHHHHHHHHHEEEEECCCCCEEHHHHHHHHHCCCCCCCCHHCCCCCCCCCH
SYLEQLFSRLRKNGLVASVRGPGGGYLLGKDASAIAVGAVITAVDESVDATRCQGKEGCQ
HHHHHHHHHHHHCCCEEEEECCCCCEEECCCCCHHHHHHHHHHHHCCCCHHHCCCCCCCC
GGNRCLTHTLWRDLSERISSFLNNITLAELVNNQDILEVADRQNNDTRRTANGRPQETIN
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCEEE
VNLRA
EEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA