Click here to switch to the map view.

The map label for this gene is recD [H]

Identifier: 170023293

GI number: 170023293

Start: 1178934

End: 1180907

Strand: Direct

Name: recD [H]

Synonym: YPK_1044

Alternate gene names: 170023293

Gene position: 1178934-1180907 (Clockwise)

Preceding gene: 170023292

Following gene: 170023295

Centisome position: 25.14

GC content: 49.44

Gene sequence:

>1974_bases
ATGATGACGCTATTGGCTCAGGCTGCTCGAGACCGCTTATTGCGCCCACTGGATGTGCAGTTTTCACGAATGATTGCCGG
CGATGATGACCCGCGGTTACAACTGGCCGCAGCGATCCTTAGTGCAGAAGTAGGGGCCGGTCATGTTTGCCTGCCATTAC
GCTATTTACAGCCAGAACTGCTATTCGGTGGGCGGCAACCCGATTTATCACTGGCGCTATGGCAGGCGGCGGGCTCGCCA
GATAAAGCACAGTGGCTACAGGCATTACAAAACGCCCCAGTAGTCAGTGATGGCTCTCAACCAACACCATTAGTGCTACA
GCAGGAACGTTTATATCTGCAACGAATGTGGCAGTACGAAGGAGATGTCGTCCAATTTATTGCCAGTGACTCTGTTTTTA
TAAACAGAGATAGTGATTTTATGACCAGTAAAGGTATTGCCACTTCTGTTGATGAATCGCTATTACGGGAGACGCTAGAC
GCTTTGTTTGGTTGTGCTGGTAGTGAGGTTGATTGGCAAAAAGTGGCGGCAGCGGTTGCGGCTACCCGTAGAATTTCAGT
TATTTCCGGCGGGCCGGGCACGGGGAAAACCACCACAGTAGCCAAACTTTTGACAGCATTGATACGGCTTAGCCAGGGGC
AACGTTTACGTATTCAACTTGCGGCCCCAACCGGTAAAGCCGCTGCACGCCTTACTGAATCACTGGGCAAAGCGATTCGG
CAATTCTTTCTTACTGATGATGAACGTAAATTATTCCCTGATCAGGCTTCGACCTTGCACCGTTTACTGGGTGTTCAGCC
CAATAGCCAGCGCCTGCGTTACCACCGTGGTAATCCATTAAATCTTGATGTACTGGTCGTTGATGAAGCATCAATGGTTG
ATTTACCTATGATGGCGCGCTTAATTGCGGCATTACCTGCCAAGGCCAAGGTGATATTCCTTGGTGACCGTGACCAACTG
GCCTCGGTTGAGGCGGGGGCGGTTCTGGGGGATATCTGCCGTTTTGCCGAATTAGGTTACAGCGAGCAACGGGCACAGCA
ATTAACTCAGTTAACGGGCTATTTATTAACTAATAATGCATTAACCAGCAATGTACTAGCCAGCAATGTACTAACCAATA
AGGCATTAGCCAATAAAGCGCAGCCAGATGAAACCTATTCTGATTCAGCGAATGTACGCGATAGCCTGTGTTTACTGCGT
AAAAGTTACCGCTTCGATGAAAAGTCAGGGATTGGGCAGCTTGCTCTGGCCGTTAATGCAGGGGAGTATCGGCAGGCTTT
ATCCGTATTAAACAGTGCGTATTCTGATGTTGAACGCTTCCCGCTGGCCGATGAGGAAGATTATCAGGTACTGCTAGAGG
CTTGTGCTGTGGGGTATCAGCATTACCTCGAACGGGTGGCTGCGTTAGCCCCTGCGGCAGAGGTATTGGCAGCATTTGGC
CGCTACCAACTGCTGTGTGCATTACGTTCCGGGCCATTCGGTGTCAGTGGCTTAAACGAACGCATTGAACAGGTTTTACA
TCGTAAAGGATTCATTATCCGTCCATCAGGGCCTTCTGGCCGTTGGTATGTTGGGCGGCCAGTGATGATAGAACTTAATG
ATAGCGCACTTGGCTTATTCAACGGGGATATTGGTATTGCCTTACATGATAATGAAGGCGAGCTGCGGGTATATTTTCAA
TTGCCCGATGGCAATATAAAGTCAGTACAACCTAGTCGCCTTCCCAGCCATGAAACCGCTTATGCTATGACGGTTCATAA
ATCGCAGGGTTCAGAGTTTGAACACACAGCATTGGTATTACCTAACACGTTCATGCCCGTGTTAACTCGTGAATTGGTCT
ATACCGCCATTACCCGCGCCCGTCAGCATCTGACGCTTTATTGCAGCGATGCCGTGCTAAGTCATGCCATACGTACACCG
ACTCTCCGGCTTAGCGGGCTAGTTGATCGCTTGAATACATTAAATCGCCAATAA

Upstream 100 bases:

>100_bases
AAGAAATGGATCGCTTATTCAGTGGCACAATTGGCAGTAACGCAACCGCGAGTGACAAAAGCGGTAGCAATGTCATTCAC
AGCGGCGAGAGGGCATCACG

Downstream 100 bases:

>100_bases
TCTCAGGGCATAAGCGCCCTGAGTTATCTGTTTCAAATAAGTATTTCAAATAAGTGTTTCAAATAAGTACTTCCAATAAG
TGATTCGAGTGCGTGAGCGT

Product: exonuclease V subunit alpha

Products: NA

Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]

Number of amino acids: Translated: 657; Mature: 657

Protein sequence:

>657_residues
MMTLLAQAARDRLLRPLDVQFSRMIAGDDDPRLQLAAAILSAEVGAGHVCLPLRYLQPELLFGGRQPDLSLALWQAAGSP
DKAQWLQALQNAPVVSDGSQPTPLVLQQERLYLQRMWQYEGDVVQFIASDSVFINRDSDFMTSKGIATSVDESLLRETLD
ALFGCAGSEVDWQKVAAAVAATRRISVISGGPGTGKTTTVAKLLTALIRLSQGQRLRIQLAAPTGKAAARLTESLGKAIR
QFFLTDDERKLFPDQASTLHRLLGVQPNSQRLRYHRGNPLNLDVLVVDEASMVDLPMMARLIAALPAKAKVIFLGDRDQL
ASVEAGAVLGDICRFAELGYSEQRAQQLTQLTGYLLTNNALTSNVLASNVLTNKALANKAQPDETYSDSANVRDSLCLLR
KSYRFDEKSGIGQLALAVNAGEYRQALSVLNSAYSDVERFPLADEEDYQVLLEACAVGYQHYLERVAALAPAAEVLAAFG
RYQLLCALRSGPFGVSGLNERIEQVLHRKGFIIRPSGPSGRWYVGRPVMIELNDSALGLFNGDIGIALHDNEGELRVYFQ
LPDGNIKSVQPSRLPSHETAYAMTVHKSQGSEFEHTALVLPNTFMPVLTRELVYTAITRARQHLTLYCSDAVLSHAIRTP
TLRLSGLVDRLNTLNRQ

Sequences:

>Translated_657_residues
MMTLLAQAARDRLLRPLDVQFSRMIAGDDDPRLQLAAAILSAEVGAGHVCLPLRYLQPELLFGGRQPDLSLALWQAAGSP
DKAQWLQALQNAPVVSDGSQPTPLVLQQERLYLQRMWQYEGDVVQFIASDSVFINRDSDFMTSKGIATSVDESLLRETLD
ALFGCAGSEVDWQKVAAAVAATRRISVISGGPGTGKTTTVAKLLTALIRLSQGQRLRIQLAAPTGKAAARLTESLGKAIR
QFFLTDDERKLFPDQASTLHRLLGVQPNSQRLRYHRGNPLNLDVLVVDEASMVDLPMMARLIAALPAKAKVIFLGDRDQL
ASVEAGAVLGDICRFAELGYSEQRAQQLTQLTGYLLTNNALTSNVLASNVLTNKALANKAQPDETYSDSANVRDSLCLLR
KSYRFDEKSGIGQLALAVNAGEYRQALSVLNSAYSDVERFPLADEEDYQVLLEACAVGYQHYLERVAALAPAAEVLAAFG
RYQLLCALRSGPFGVSGLNERIEQVLHRKGFIIRPSGPSGRWYVGRPVMIELNDSALGLFNGDIGIALHDNEGELRVYFQ
LPDGNIKSVQPSRLPSHETAYAMTVHKSQGSEFEHTALVLPNTFMPVLTRELVYTAITRARQHLTLYCSDAVLSHAIRTP
TLRLSGLVDRLNTLNRQ
>Mature_657_residues
MMTLLAQAARDRLLRPLDVQFSRMIAGDDDPRLQLAAAILSAEVGAGHVCLPLRYLQPELLFGGRQPDLSLALWQAAGSP
DKAQWLQALQNAPVVSDGSQPTPLVLQQERLYLQRMWQYEGDVVQFIASDSVFINRDSDFMTSKGIATSVDESLLRETLD
ALFGCAGSEVDWQKVAAAVAATRRISVISGGPGTGKTTTVAKLLTALIRLSQGQRLRIQLAAPTGKAAARLTESLGKAIR
QFFLTDDERKLFPDQASTLHRLLGVQPNSQRLRYHRGNPLNLDVLVVDEASMVDLPMMARLIAALPAKAKVIFLGDRDQL
ASVEAGAVLGDICRFAELGYSEQRAQQLTQLTGYLLTNNALTSNVLASNVLTNKALANKAQPDETYSDSANVRDSLCLLR
KSYRFDEKSGIGQLALAVNAGEYRQALSVLNSAYSDVERFPLADEEDYQVLLEACAVGYQHYLERVAALAPAAEVLAAFG
RYQLLCALRSGPFGVSGLNERIEQVLHRKGFIIRPSGPSGRWYVGRPVMIELNDSALGLFNGDIGIALHDNEGELRVYFQ
LPDGNIKSVQPSRLPSHETAYAMTVHKSQGSEFEHTALVLPNTFMPVLTRELVYTAITRARQHLTLYCSDAVLSHAIRTP
TLRLSGLVDRLNTLNRQ

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=643, Percent_Identity=56.1430793157076, Blast_Score=642, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 72021; Mature: 72021

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTLLAQAARDRLLRPLDVQFSRMIAGDDDPRLQLAAAILSAEVGAGHVCLPLRYLQPEL
CHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEHHHCCHHH
LFGGRQPDLSLALWQAAGSPDKAQWLQALQNAPVVSDGSQPTPLVLQQERLYLQRMWQYE
HCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEHHHHHHHHHHHHCC
GDVVQFIASDSVFINRDSDFMTSKGIATSVDESLLRETLDALFGCAGSEVDWQKVAAAVA
CCCEEEEECCCEEEECCCCCHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
ATRRISVISGGPGTGKTTTVAKLLTALIRLSQGQRLRIQLAAPTGKAAARLTESLGKAIR
HHHEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHH
QFFLTDDERKLFPDQASTLHRLLGVQPNSQRLRYHRGNPLNLDVLVVDEASMVDLPMMAR
HHHCCCCCHHCCCCHHHHHHHHHCCCCCCCHHHEECCCCCEEEEEEECCCCCCCHHHHHH
LIAALPAKAKVIFLGDRDQLASVEAGAVLGDICRFAELGYSEQRAQQLTQLTGYLLTNNA
HHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEECCC
LTSNVLASNVLTNKALANKAQPDETYSDSANVRDSLCLLRKSYRFDEKSGIGQLALAVNA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECC
GEYRQALSVLNSAYSDVERFPLADEEDYQVLLEACAVGYQHYLERVAALAPAAEVLAAFG
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
RYQLLCALRSGPFGVSGLNERIEQVLHRKGFIIRPSGPSGRWYVGRPVMIELNDSALGLF
HHHEEEEECCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCEEECCEEEEEECCCEEEEE
NGDIGIALHDNEGELRVYFQLPDGNIKSVQPSRLPSHETAYAMTVHKSQGSEFEHTALVL
ECCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEC
PNTFMPVLTRELVYTAITRARQHLTLYCSDAVLSHAIRTPTLRLSGLVDRLNTLNRQ
CCCHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMTLLAQAARDRLLRPLDVQFSRMIAGDDDPRLQLAAAILSAEVGAGHVCLPLRYLQPEL
CHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEHHHCCHHH
LFGGRQPDLSLALWQAAGSPDKAQWLQALQNAPVVSDGSQPTPLVLQQERLYLQRMWQYE
HCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEHHHHHHHHHHHHCC
GDVVQFIASDSVFINRDSDFMTSKGIATSVDESLLRETLDALFGCAGSEVDWQKVAAAVA
CCCEEEEECCCEEEECCCCCHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
ATRRISVISGGPGTGKTTTVAKLLTALIRLSQGQRLRIQLAAPTGKAAARLTESLGKAIR
HHHEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHH
QFFLTDDERKLFPDQASTLHRLLGVQPNSQRLRYHRGNPLNLDVLVVDEASMVDLPMMAR
HHHCCCCCHHCCCCHHHHHHHHHCCCCCCCHHHEECCCCCEEEEEEECCCCCCCHHHHHH
LIAALPAKAKVIFLGDRDQLASVEAGAVLGDICRFAELGYSEQRAQQLTQLTGYLLTNNA
HHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEECCC
LTSNVLASNVLTNKALANKAQPDETYSDSANVRDSLCLLRKSYRFDEKSGIGQLALAVNA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECC
GEYRQALSVLNSAYSDVERFPLADEEDYQVLLEACAVGYQHYLERVAALAPAAEVLAAFG
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
RYQLLCALRSGPFGVSGLNERIEQVLHRKGFIIRPSGPSGRWYVGRPVMIELNDSALGLF
HHHEEEEECCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCEEECCEEEEEECCCEEEEE
NGDIGIALHDNEGELRVYFQLPDGNIKSVQPSRLPSHETAYAMTVHKSQGSEFEHTALVL
ECCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEC
PNTFMPVLTRELVYTAITRARQHLTLYCSDAVLSHAIRTPTLRLSGLVDRLNTLNRQ
CCCHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3537961; 9278503; 3537960 [H]