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The map label for this gene is yafC [H]

Identifier: 170022911

GI number: 170022911

Start: 720697

End: 721608

Strand: Direct

Name: yafC [H]

Synonym: YPK_0660

Alternate gene names: 170022911

Gene position: 720697-721608 (Clockwise)

Preceding gene: 170022910

Following gene: 170022913

Centisome position: 15.37

GC content: 53.51

Gene sequence:

>912_bases
ATGAAAGTCACGTTGGAAGAGTTGCAGGCATTTACCTCGGTAGTGGACTGCGGCTCTATCACGGCTGCGGCAGAGCAGCG
CAGCCAAACGACATCGGGGATTAGCCGGGCATTGAGTCGGCTAGAGCAGAAGCTGGCGACAACGTTGCTACGCCGTACGA
CTCGGCGTCTGGCGCTGACAGAAGAGGGGGCGCTGTTCCTCAGTCATGCGCGGCAGATTATCGGCGCAGTCGATGATGCT
GAAGAGCAAATTGCCCTGAGGCGGTTGAAGCCTGCTGGCCGGTTACGAGTTAATGCGGCAGCTCCTTTTATGCAACATGT
CATTGTGCCGATGATCACCGGTTTCCGTGCGTTGTATCCGCAAATCACGTTGGAATTGAATACCGACGATCTCAATATCG
ATCTGCTTGAGCAGCGCACTGACATTGCTATCCGTATCGGTGCGTTGAGGGATTCGACGATCCATGCCCGGCTGCTTGGT
GCCAGCCGGGTGCGTCTGCTTGCCAGCCCTAACTACCTACAACGTCACGGTACGCCTCACACCATTGAGGCACTGGCAGA
TCACAGCCTGCTGGGCTTTACTCAGCCCGAATTTCTTAATCAGTGGTCATTACCCCATTTACCCGGCGGGCGTTCGTCAA
TTATCCCCAACTTGGCGGCTTCCAGCGGTGAGACTCTGCGTTTACTGGCTTTACAGGGCGAAGGGATTGCCGAACTCTCT
GATTTCATGACCCGCGAGGATCAATTAGCCGGGCGCTTAGTCGAGGTTCTGGCTGATCAAATTCTAGAGACTTGGCAACC
GATCAACGCCGTTTATTACCGTAATACTCAGCTTGCTGCGCGCATTACCTGTTTTCTTGATTATGTTAGTGAACAGATTA
AGTTACAGGGGAGTCACTGGCTAAGAATATAA

Upstream 100 bases:

>100_bases
TCTGGCCGTTATGGATATGTTGTTGGCAAAGAAACGCTCGGAAGATCGCCGCAACTGGCTACAAGAGAAAGGGGATACTG
CTGAGATCGAGGTCTGATCG

Downstream 100 bases:

>100_bases
ATGAGGGAGGGGTAACGTATAAAACGGCCCTCCCCAGAGAGAGGAGGGCCGAACCGCTTAGCTGTTAACGTTTTCGGCTA
AGTGCTGACGATAGCGGGCA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MKVTLEELQAFTSVVDCGSITAAAEQRSQTTSGISRALSRLEQKLATTLLRRTTRRLALTEEGALFLSHARQIIGAVDDA
EEQIALRRLKPAGRLRVNAAAPFMQHVIVPMITGFRALYPQITLELNTDDLNIDLLEQRTDIAIRIGALRDSTIHARLLG
ASRVRLLASPNYLQRHGTPHTIEALADHSLLGFTQPEFLNQWSLPHLPGGRSSIIPNLAASSGETLRLLALQGEGIAELS
DFMTREDQLAGRLVEVLADQILETWQPINAVYYRNTQLAARITCFLDYVSEQIKLQGSHWLRI

Sequences:

>Translated_303_residues
MKVTLEELQAFTSVVDCGSITAAAEQRSQTTSGISRALSRLEQKLATTLLRRTTRRLALTEEGALFLSHARQIIGAVDDA
EEQIALRRLKPAGRLRVNAAAPFMQHVIVPMITGFRALYPQITLELNTDDLNIDLLEQRTDIAIRIGALRDSTIHARLLG
ASRVRLLASPNYLQRHGTPHTIEALADHSLLGFTQPEFLNQWSLPHLPGGRSSIIPNLAASSGETLRLLALQGEGIAELS
DFMTREDQLAGRLVEVLADQILETWQPINAVYYRNTQLAARITCFLDYVSEQIKLQGSHWLRI
>Mature_303_residues
MKVTLEELQAFTSVVDCGSITAAAEQRSQTTSGISRALSRLEQKLATTLLRRTTRRLALTEEGALFLSHARQIIGAVDDA
EEQIALRRLKPAGRLRVNAAAPFMQHVIVPMITGFRALYPQITLELNTDDLNIDLLEQRTDIAIRIGALRDSTIHARLLG
ASRVRLLASPNYLQRHGTPHTIEALADHSLLGFTQPEFLNQWSLPHLPGGRSSIIPNLAASSGETLRLLALQGEGIAELS
DFMTREDQLAGRLVEVLADQILETWQPINAVYYRNTQLAARITCFLDYVSEQIKLQGSHWLRI

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=294, Percent_Identity=43.8775510204082, Blast_Score=255, Evalue=3e-69,
Organism=Escherichia coli, GI1789639, Length=298, Percent_Identity=30.5369127516779, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI145693193, Length=303, Percent_Identity=29.042904290429, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1789440, Length=277, Percent_Identity=29.6028880866426, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI87081978, Length=291, Percent_Identity=28.8659793814433, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1787128, Length=295, Percent_Identity=28.4745762711864, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787589, Length=304, Percent_Identity=25, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1789173, Length=272, Percent_Identity=27.9411764705882, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788481, Length=302, Percent_Identity=27.1523178807947, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788706, Length=304, Percent_Identity=23.3552631578947, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787879, Length=162, Percent_Identity=32.0987654320988, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1786448, Length=184, Percent_Identity=27.1739130434783, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790262, Length=258, Percent_Identity=26.3565891472868, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI87082132, Length=161, Percent_Identity=26.7080745341615, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33673; Mature: 33673

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVTLEELQAFTSVVDCGSITAAAEQRSQTTSGISRALSRLEQKLATTLLRRTTRRLALT
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EEGALFLSHARQIIGAVDDAEEQIALRRLKPAGRLRVNAAAPFMQHVIVPMITGFRALYP
CCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHCC
QITLELNTDDLNIDLLEQRTDIAIRIGALRDSTIHARLLGASRVRLLASPNYLQRHGTPH
EEEEEECCCCCCEEHHHCCCCEEEEEECCCCCCHHHHHHCHHHEEEEECCCHHHHCCCCH
TIEALADHSLLGFTQPEFLNQWSLPHLPGGRSSIIPNLAASSGETLRLLALQGEGIAELS
HHHHHHCCCCCCCCCHHHHCCCCCCCCCCCCHHHCCCHHCCCCCEEEEEEECCCCHHHHH
DFMTREDQLAGRLVEVLADQILETWQPINAVYYRNTQLAARITCFLDYVSEQIKLQGSHW
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHEECCCCE
LRI
ECC
>Mature Secondary Structure
MKVTLEELQAFTSVVDCGSITAAAEQRSQTTSGISRALSRLEQKLATTLLRRTTRRLALT
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EEGALFLSHARQIIGAVDDAEEQIALRRLKPAGRLRVNAAAPFMQHVIVPMITGFRALYP
CCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHCC
QITLELNTDDLNIDLLEQRTDIAIRIGALRDSTIHARLLGASRVRLLASPNYLQRHGTPH
EEEEEECCCCCCEEHHHCCCCEEEEEECCCCCCHHHHHHCHHHEEEEECCCHHHHCCCCH
TIEALADHSLLGFTQPEFLNQWSLPHLPGGRSSIIPNLAASSGETLRLLALQGEGIAELS
HHHHHHCCCCCCCCCHHHHCCCCCCCCCCCCHHHCCCHHCCCCCEEEEEEECCCCHHHHH
DFMTREDQLAGRLVEVLADQILETWQPINAVYYRNTQLAARITCFLDYVSEQIKLQGSHW
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHEECCCCE
LRI
ECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]