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The map label for this gene is kdsD [H]

Identifier: 170022761

GI number: 170022761

Start: 560789

End: 561862

Strand: Reverse

Name: kdsD [H]

Synonym: YPK_0510

Alternate gene names: 170022761

Gene position: 561862-560789 (Counterclockwise)

Preceding gene: 170022762

Following gene: 170022760

Centisome position: 11.98

GC content: 50.65

Gene sequence:

>1074_bases
ATGCTCAGGAAGGCTTGGAGCGAAAGCAACCAACACACCTACAGCGTGAAAGATGACGGTAATACCAACATTGGGCGGAT
ATTAAGTATGTCTACTTTTGATTTACAGCCGGGCGTGGATTTCCAGCAGGCAGGTAAGCAGGTACTTCAGATTGAACGCG
AAGGGCTGGCTCAACTCGATCAATACATAAACGAGGATTTCTCCAGAGCCTGTGAGGCCATTTTTCGTTGCCACGGCAAA
GTCGTCGTGATGGGAATGGGCAAATCTGGTCATATTGGCTGCAAAATTGCAGCCACATTCGCCAGCACGGGCACACCTGC
ATTTTTTGTCCATCCTGGTGAAGCCAGCCATGGCGATTTGGGCATGATCACGCCACAAGATATTGTATTAGCTATCTCTA
ACTCTGGGGAATCCAACGAAATCCTCACGTTGATCCCCGTGCTTAAGCGCCAGAAAATTCTGTTGATTTGCATGAGCAGT
AACCCTGAGAGCACCATGGGTAAAGCGGCCGATATTCACTTGTGCATTAATGTGCCACAAGAGGCCTGTCCGCTGGGGCT
AGCGCCAACCACCAGTACGACTGCAACACTGGTTATGGGGGATGCGTTGGCGGTAGCCTTGCTCAAAGCACGGGGTTTCA
CGCAGGAAGATTTCGCACTCTCTCACCCAGGTGGCGCGCTGGGGCGTAAGTTGCTGCTGCGGATCAGCGATATTATGCAT
ACGGGTACGGAGATCCCCACCGTCAGCCCTGATGCATCATTACGTGATGCCTTGCTAGAAATTACTCGGAAAAGTCTGGG
TTTGACCGTTATTTGTGACGATTCAATGAGGATTAAAGGTATCTTTACCGACGGTGACTTGCGCCGGGTATTTGATATGG
GCATTGATCTGAATAATGCAAAAATTGCTGACGTCATGACTCGCGGGGGTATTCGAGTCCCTCCGAACATATTGGCGGTG
GACGCGCTCAATCTGATGGAGTCACGCCATATCACTGCGTTGCTCGTCGCTGATGGTGACCAATTACTGGGTGTCGTACA
TATGCACGATATGCTGAGAGCCGGTGTTGTCTGA

Upstream 100 bases:

>100_bases
TGGCAGGCGCTCTGTTATTATGTGGGTTTATCACTTATCTTGCGGTGTTGTTTTTTGCTCCCATAAGTGCGCTGTAAAAT
ACATTTCCCTATAAATTTCA

Downstream 100 bases:

>100_bases
CAGTTTAGTTGAGTCAATGAGCGCCGCGAACAATGCTATCAGTCAGTGATTCGGGTGAGTGAGTGAGTGCCGCTACCAAT
GTTGTAACTTCAACAACGTT

Product: D-arabinose 5-phosphate isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MLRKAWSESNQHTYSVKDDGNTNIGRILSMSTFDLQPGVDFQQAGKQVLQIEREGLAQLDQYINEDFSRACEAIFRCHGK
VVVMGMGKSGHIGCKIAATFASTGTPAFFVHPGEASHGDLGMITPQDIVLAISNSGESNEILTLIPVLKRQKILLICMSS
NPESTMGKAADIHLCINVPQEACPLGLAPTTSTTATLVMGDALAVALLKARGFTQEDFALSHPGGALGRKLLLRISDIMH
TGTEIPTVSPDASLRDALLEITRKSLGLTVICDDSMRIKGIFTDGDLRRVFDMGIDLNNAKIADVMTRGGIRVPPNILAV
DALNLMESRHITALLVADGDQLLGVVHMHDMLRAGVV

Sequences:

>Translated_357_residues
MLRKAWSESNQHTYSVKDDGNTNIGRILSMSTFDLQPGVDFQQAGKQVLQIEREGLAQLDQYINEDFSRACEAIFRCHGK
VVVMGMGKSGHIGCKIAATFASTGTPAFFVHPGEASHGDLGMITPQDIVLAISNSGESNEILTLIPVLKRQKILLICMSS
NPESTMGKAADIHLCINVPQEACPLGLAPTTSTTATLVMGDALAVALLKARGFTQEDFALSHPGGALGRKLLLRISDIMH
TGTEIPTVSPDASLRDALLEITRKSLGLTVICDDSMRIKGIFTDGDLRRVFDMGIDLNNAKIADVMTRGGIRVPPNILAV
DALNLMESRHITALLVADGDQLLGVVHMHDMLRAGVV
>Mature_357_residues
MLRKAWSESNQHTYSVKDDGNTNIGRILSMSTFDLQPGVDFQQAGKQVLQIEREGLAQLDQYINEDFSRACEAIFRCHGK
VVVMGMGKSGHIGCKIAATFASTGTPAFFVHPGEASHGDLGMITPQDIVLAISNSGESNEILTLIPVLKRQKILLICMSS
NPESTMGKAADIHLCINVPQEACPLGLAPTTSTTATLVMGDALAVALLKARGFTQEDFALSHPGGALGRKLLLRISDIMH
TGTEIPTVSPDASLRDALLEITRKSLGLTVICDDSMRIKGIFTDGDLRRVFDMGIDLNNAKIADVMTRGGIRVPPNILAV
DALNLMESRHITALLVADGDQLLGVVHMHDMLRAGVV

Specific function: Catalyzes the interconversion of D-arabinose 5-phosphate and D-ribulose 5-phosphate [H]

COG id: COG0794

COG function: function code M; Predicted sugar phosphate isomerase involved in capsule formation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1789588, Length=328, Percent_Identity=77.4390243902439, Blast_Score=530, Evalue=1e-152,
Organism=Escherichia coli, GI87082151, Length=315, Percent_Identity=48.5714285714286, Blast_Score=291, Evalue=4e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000644
- InterPro:   IPR004800
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00571 CBS; PF01380 SIS [H]

EC number: =5.3.1.13 [H]

Molecular weight: Translated: 38366; Mature: 38366

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRKAWSESNQHTYSVKDDGNTNIGRILSMSTFDLQPGVDFQQAGKQVLQIEREGLAQLD
CCCCCCCCCCCEEEEECCCCCCCHHHEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
QYINEDFSRACEAIFRCHGKVVVMGMGKSGHIGCKIAATFASTGTPAFFVHPGEASHGDL
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEEEEECCCCCEEEEECCCCCCCCE
GMITPQDIVLAISNSGESNEILTLIPVLKRQKILLICMSSNPESTMGKAADIHLCINVPQ
ECCCCCEEEEEEECCCCCCCEEEEEEHHCCCEEEEEEECCCCCHHCCCCEEEEEEEECCH
EACPLGLAPTTSTTATLVMGDALAVALLKARGFTQEDFALSHPGGALGRKLLLRISDIMH
HHCCCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHHHHHH
TGTEIPTVSPDASLRDALLEITRKSLGLTVICDDSMRIKGIFTDGDLRRVFDMGIDLNNA
CCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCEEEEEEECCCHHHHHHHCCCCCCCC
KIADVMTRGGIRVPPNILAVDALNLMESRHITALLVADGDQLLGVVHMHDMLRAGVV
CHHHHHHCCCCCCCCCEEEEHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLRKAWSESNQHTYSVKDDGNTNIGRILSMSTFDLQPGVDFQQAGKQVLQIEREGLAQLD
CCCCCCCCCCCEEEEECCCCCCCHHHEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
QYINEDFSRACEAIFRCHGKVVVMGMGKSGHIGCKIAATFASTGTPAFFVHPGEASHGDL
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEEEEECCCCCEEEEECCCCCCCCE
GMITPQDIVLAISNSGESNEILTLIPVLKRQKILLICMSSNPESTMGKAADIHLCINVPQ
ECCCCCEEEEEEECCCCCCCEEEEEEHHCCCEEEEEEECCCCCHHCCCCEEEEEEEECCH
EACPLGLAPTTSTTATLVMGDALAVALLKARGFTQEDFALSHPGGALGRKLLLRISDIMH
HHCCCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHHHHHH
TGTEIPTVSPDASLRDALLEITRKSLGLTVICDDSMRIKGIFTDGDLRRVFDMGIDLNNA
CCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCEEEEEEECCCHHHHHHHCCCCCCCC
KIADVMTRGGIRVPPNILAVDALNLMESRHITALLVADGDQLLGVVHMHDMLRAGVV
CHHHHHHCCCCCCCCCEEEEHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]